Bcl11a is essential for normal lymphoid development

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BCL11A +58/+55 enhancer-editing facilitates HSPC engraftment and HbF induction in rhesus macaques conditioned with a CD45 antibody-drug conjugate

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miR-146a induces apoptosis in neuroblastoma cells by targeting BCL11A

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Load and lock: the molecular mechanisms of B‐lymphocyte commitment

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The Unsolved Puzzle of c-Rel in B Cell Lymphoma

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BCL11A Is Oncogenic and Predicts Poor Outcomes in Natural Killer/T-Cell Lymphoma

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Expression of zinc finger transcription factor Bcl11A/Evi9/CTIP1 in rat brain

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Transcriptional control of natural killer cell differentiation and function

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CRISPR/Cas9 system and its applications in human hematopoietic cells

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Advances in genome editing: the technology of choice for precise and efficient β-thalassemia treatment

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A Small Key for a Heavy Door: Genetic Therapies for the Treatment of Hemoglobinopathies

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Genomic Alterations in Hodgkin's Lymphoma

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Therapeutic gene editing strategies using CRISPR-Cas9 for the β-hemoglobinopathies

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Dendritic cell functions in vivo: A user's guide to current and next‐ generation mutant mouse models

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Molecular resolution of the B cell landscape

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Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin

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Impact of ZBTB7A hypomethylation and expression patterns on treatment response to hydroxyurea

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BCL11A Down-Regulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells

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Expression of essential B cell development genes in horses with common variable immunodeficiency

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BRAFV600E induces key features of LCH in iPSCs with cell type–specific phenotypes and drug responses

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Recent advances in globin research using genome‐wide association studies and gene editing

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The Fetal-to-Adult Hemoglobin Switch — Mechanism and Therapy

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The Role of Bcl11 Transcription Factors in Neurodevelopmental Disorders

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Immunoglobulin gene translocations in chronic lymphocytic leukemia: A report of 35 patients and review of the literature

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Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency

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Tumor-Specific Genetic Lesions and Their Influence on Therapy in Pediatric Acute Lymphoblastic Leukemia

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Treating Sickle Cell Disease: Gene Therapy Approaches

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Genome Editing Therapy for the Blood: Ex Vivo Success and In Vivo Prospects

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Genetic and Epigenetic Control of Early Lymphocyte Development

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Hoxa13 regulates expression of common Hox target genes involved in cartilage development to coordinate the expansion of the autopodal anlage

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Multi-modular structure of the gene regulatory network for specification and commitment of murine T cells

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Potential DNA markers as a rapid tracing tool for animal adulterants in vegetarian food

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Gene Regulatory Networks Orchestrating B Cell Fate Specification, Commitment, and Differentiation

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GWAS to Therapy by Genome Edits?

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The BCL11A-XL expression predicts relapse in squamous cell carcinoma and large cell carcinoma.

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Genome-Wide Association Study of Susceptibility Loci for TCF3-PBX1 Acute Lymphoblastic Leukemia in Children

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Analysis of the expression of PHTF1 and related genes in acute lymphoblastic leukemia

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Transcriptional Repressor BCL11A in Erythroid Cells

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The expression pattern of Bcl11a, Mdm2 and Pten genes in B‐cell acute lymphoblastic leukemia

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BCL11A is a SUMOylated protein and recruits SUMO‐conjugation enzymes in its nuclear body

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Acute mixed lineage leukemia and a t(6;14)(q25;q32) in two adults

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Establishment and Maintenance of B Cell IdentityPreprint

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Physiological and Aberrant γ-Globin Transcription During Development

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The DNA repair function of BCL11A suppresses senescence and promotes continued proliferation of triple-negative breast cancer cells

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C2H2 Zinc Finger Transcription Factors Associated with Hemoglobinopathies

Zhang, X., Xia, F., Zhang, X., Blumenthal, R., & Cheng, X. (2023) · Journal of Molecular Biology · doi:10.1016/j.jmb.2023.168343 · Cited by 12

Combination of BCL11A siRNA with vincristine increases the apoptosis of SUDHL6 cells

He, D., Wu, H., Li, D., & Li, Y. (2014) · European journal of medical research · doi:10.1186/2047-783x-19-34 · Cited by 12

A mutant BCL11B-N440K protein interferes with BCL11A function during T lymphocyte and neuronal development

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Cross-species single-cell analysis reveals divergence and conservation of peripheral blood mononuclear cells

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Redirecting E3 ubiquitin ligases for targeted protein degradation with heterologous recognition domains

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Down-regulation of the transcriptional repressor ZNF802 (JAZF1) reactivates fetal hemoglobin in β0-thalassemia/HbE

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Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression

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Gene Editing-Based Technologies for Beta-hemoglobinopathies Treatment

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Proviral integration of an Abelson-murine leukemia virus deregulates BKLF-expression in the hypermutating pre-B cell line 18-81

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Influences of Genetic Variation on Fetal Hemoglobin

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Efficient Correction of the Sickle Mutation in Human Hematopoietic Stem Cells Using a Cas9 Ribonucleoprotein ComplexPreprint

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A common signaling pathway is activated in erythroid cells expressing high levels of fetal hemoglobin: a potential role for cAMP-elevating agents in β-globin disorders

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p53-Dependent Transcriptional Responses to Interleukin-3 Signaling

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Effects of Prednisolone on Specifically Expressed Genes in Pediatric Acute B-lymphoblastic Leukemia

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A transcriptome-based approach to identify functional modules within and across primary human immune cells

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Innovative Therapies for Hemoglobin Disorders

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Lymphoid origin of intrinsically activated plasmacytoid dendritic cells in micePreprint

Araujo, A. M., Dekker, J. D., Garrison, K., Su, Z., Rhee, C., Hu, Z., Lee, B., Osorio, D., Lee, J., Iyer, V. R., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/310680 · Cited by 10

Multiplex base editing of BCL11A regulatory elements to treat sickle cell disease

Fontana, L., Martinucci, P., Amistadi, S., Félix, T., Mombled, M., Tachtsidi, A., Corre, G., Chalumeau, A., Hardouin, G., Martin, J., et al. (2025) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.102376 · Cited by 9

Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B

Papadopoulos, P., Kafasi, A., Cuyper, I. M. D., Barroca, V., Lewandowski, D., Kadri, Z., Veldthuis, M., Berghuis, J., Gillemans, N., Cuesta, C. B., et al. (2020) · Human Genomics · doi:10.1186/s40246-020-00283-3 · Cited by 9

Comparative analysis of hepatocellular carcinoma and cirrhosis gene expression profiles

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Gene expression profile analysis of SUDHL6 cells with siRNA‐mediated BCL11A downregulation

Wu, H., Gao, Y., Ding, L., He, D., & Li, Y. (2014) · Cell Biology International · doi:10.1002/cbin.10332 · Cited by 9

Dual role of BCL11B in T-cell malignancies

Przybylski, G. K., Przybylska, J., & Li, Y. (2024) · Blood Science · doi:10.1097/bs9.0000000000000204 · Cited by 8

Expression of the B-cell lymphoma/leukemia 11A gene in malignant hematological cell lines through quantitative reverse transcription polymerase chain reaction

Gao, Y., He, D., Chen, S., Yan, X., Hu, X., & Li, Y. (2011) · Clinical Oncology and Cancer Research · doi:10.1007/s11805-011-0588-2 · Cited by 7

CRISPR Editing Enables Consequential Tag-Activated MicroRNA-Mediated Endogene Deactivation

Papasavva, P. L., Patsali, P., Loucari, C. C., Kurita, R., Nakamura, Y., Kleanthous, M., & Lederer, C. W. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23031082 · Cited by 7

BCL11A Expression in Breast Cancer

Kątnik, E., Gomułkiewicz, A., Piotrowska, A., Grzegrzółka, J., Rusak, A., Kmiecik, A. M., Ratajczak‐Wielgomas, K., & Dzięgiel, P. (2023) · Current Issues in Molecular Biology · doi:10.3390/cimb45040175 · Cited by 7

ZNF16 (HZF1) promotes erythropoiesis and megakaryocytopoiesis via regulation of the c-KIT gene

Chen, J., Li, X., Su, R. J., Song, L., Wang, F., & Zhang, J. (2013) · Biochemical Journal · doi:10.1042/bj20130628 · Cited by 8

Transcriptional repressors, corepressors and chromatin modifying enzymes in T cell development

Shapiro, M. J., & Shapiro, V. S. (2010) · Cytokine · doi:10.1016/j.cyto.2010.11.013 · Cited by 7

Curing Sickle Cell Disease by Allogeneic Hematopoietic Stem Cell (HSC) Transplantation Toward In Vivo HSC Gene Therapy

Kansal, R. (2025) · Genes · doi:10.3390/genes16111367 · Cited by 6

Lymphoid origin of intrinsically activated plasmacytoid dendritic cells in mice

Araujo, A. M., Dekker, J. D., Garrison, K., Su, Z., Rhee, C., Hu, Z., Lee, B., Osorio, D., Lee, J., Iyer, V. R., et al. (2024) · eLife · doi:10.7554/elife.96394 · Cited by 6

Identification of a genomic DNA sequence that quantitatively modulates KLF1 transcription factor expression in differentiating human hematopoietic cells

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Clinical Significance of the Transcription Factor SOX11, Cell-Cell Adhesion Protein E-cadherin and Zinc Finger Protein BCL11A in the Diagnosis of Breast Cancer

Salama, S., Hamdy, N. Μ., Elshimy, R. A. A., & EL-Mesallamy, H. O. (2021) · Archives of Pharmaceutical Sciences Ain Shams University · doi:10.21608/aps.2021.75847.1058 · Cited by 6

Chromatin landscape and epigenetic heterogeneity of acute myeloid leukaemia

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APEX1 Nuclease and Redox Functions are Both Essential for Adult Mouse Hematopoietic Stem and Progenitor Cells

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Transcriptional regulation in the development and dysfunction of neocortical projection neurons

Wang, N., Wan, R., & Tang, K. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.379039 · Cited by 6

Programmed differentiated natural killer cells kill leukemia cells by engaging SLAM family receptors

Wu, Y., Li, Y., Fu, B., Jin, L., Zheng, X., Zhang, A., Sun, R., Zhigang, T., & Wei, H. (2017) · Oncotarget · doi:10.18632/oncotarget.18659 · Cited by 5

The transcription factor Bcl11a is essential for B-1a cell maintenance during aging

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Gene Therapy for Sickle Cell Anemia in India - Current Status and Challenges

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Abnormalities of the structure and synthesis of hemoglobin

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A Bcl11bN797K variant isolated from an immunodeficient patient inhibits early thymocyte development in mice

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