Bcl11a is essential for normal lymphoid development

Notch Signaling: Cell Fate Control and Signal Integration in Development

Artavanis-Tsakonas, S., Rand, M. D., & Lake, R. J. (1999) · Science · doi:10.1126/science.284.5415.770 · Cited by 5,909

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

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Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow

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AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis.

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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

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Requirement of transcription factor PU.1 in the development of multiple hematopoietic lineages

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Deficient T Cell Fate Specification in Mice with an Induced Inactivation of Notch1

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B Cell Development Pathways

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Commitment to the B-lymphoid lineage depends on the transcription factor Pax5

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Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities

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Genetic polymorphisms in gynecologic cancers

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RNA-seq analysis reveals candidate genes associated with proliferation, invasion, and migration in BCL11A knockdown B-NHL cell lines

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Fetal Hemoglobin Research and Clinical Relevance in Sickle Cell Disease

Gudmundsdóttir, B. K., & Tisdale, J. F. (2025) · Physiology · doi:10.1152/physiol.00024.2025 · Cited by 1

New Gene Therapy Strategy for β-Thalassemia

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Autoinhibitory feedback preserves intestinal stem cell maintenance and fate commitment

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Reactivation of Fetal Hemoglobin in Thalassemia and Sickle Cell Disease

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B-Cell Repertoire Changes in Mouse Models of Aging

Scholz, J. L., Quinn, W. J., & Cancro, M. P. (2009) · Springer eBooks · doi:10.1007/978-1-4020-9063-9_20 · Cited by 1

BCL11B upregulates the expression of RelA in T cells stimulated with staphylococcal enterotoxin A

Yan, Y., Wang, S., & Lin, C. (2022) · Bulletin of Experimental Biology and Medicine · doi:10.47056/0365-9615-2022-174-8-228-234 · Cited by 1

Chronic Lymphocytic Leukemia with Translocation (2;14)(p16;q32): A Case Report and Review of the Literature

Socola, F. A., Insuasti‐Beltran, G., Lobo, R. H., Atrash, S., & Sasapu, A. (2016) · Case Reports in Oncological Medicine · doi:10.1155/2016/9037436 · Cited by 1

From DNA Topology to Pubertal Onset: Using Integrative Genomic Approaches to Study Transcriptional Regulation

Hou, H. (2019) · TSpace (University of Toronto) · Cited by 1

The generation of a Bcl11a lineage tracing mouse modelPreprint

Pensa, S., Liu, P., & Khaled, W. T. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.26.453822 · Cited by 1

Functional characterization of the B-cell lymphoma/leukemia 11A (BCL11A) transcription factor

Lee, B.-S. (2007) · Texas ScholarWorks (Texas Digital Library)

Studies on Genetic Aberrations in Acute Myeloid Leukemia

Abbas, S. (2011) · EUR Research Repository (Erasmus University Rotterdam)

ELUCIDATING REGULATORY NETWORKS PROMOTING B-CELL DEVELOPMENT

Welinder, E. (2012) · Lund University Publications (Lund University)

Role of Pre-B Cell Receptor Signaling Molecules in B Cell Differentiation and Tumor Suppression

Tạ, T. B. (2005) · RePub (Erasmus University Rotterdam)

Computational Biology-Driven Genomic and Epigenomic Delineation of Acute Myeloid Leukemia

Sanders, M. A. (2015) · EUR Research Repository (Erasmus University Rotterdam)

Progress on genes related to fetal hemoglobin quantitative trait

Guo, X. (2010) · Hereditas (Beijing) · doi:10.3724/sp.j.1005.2010.00295

Differential effects of mutant TAp63γ on transactivation of p53 and/or p63 responsive genes and their effects on global gene expression

Khokhar, S. (2007) · CORE Scholar (Wright State University)

Elucidation of Mechanisms of Fetal Hemoglobin Regulation by CRISPR/Cas9 Mediated Genome Editing

Canver, M. C. (2016) · Digital Access to Scholarship at Harvard (DASH) (Harvard University)

Partners in crime

Buckland, J. (2003) · Nature reviews. Immunology · doi:10.1038/nri1119

Development and application of bioinformatic methods to analyze genome-wide expression and survival data from cancer patients

Bueno-Fortes, S. (2019) · doi:10.14201/gredos.140370

Molecular mechanisms in lymphoid restriction : securing the B lineage fate

Åhsberg, J. (2014) · Linköping University medical dissertations · doi:10.3384/diss.diva-114273

The Adaptive Immune Response

Hesslein, D. G. T., Aguila, H. L., & Horowitz, M. C. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-375670-1.10003-2 · Cited by 1

B Cell Repertoire Changes in Mouse Models of Aging

Scholz, J. L., Hao, Y., Quinn, W. J., & Cancro, M. P. (2017) · Springer eBooks · doi:10.1007/978-3-319-64597-1_20-1

B Cell Repertoire Changes in Mouse Models of Aging

Scholz, J. L., Hao, Y., Quinn, W. J., & Cancro, M. P. (2019) · Springer eBooks · doi:10.1007/978-3-319-99375-1_20

Faculty Opinions recommendation of Runx1-Cbfβ facilitates early B lymphocyte development by regulating expression of Ebf1.

Bassing, C. H. (2012) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.717952224.793457633

Faculty Opinions recommendation of Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks.

Yip, K. Y.-L. (2019) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.734659860.793556264

The Role of Sp1 and Sp3 Transcription Factors in Hematopoiesis

Kulu, D. (2013) · RePub (Erasmus University Rotterdam)

Effects of Quantitative Trait Loci (QTLs) of BCL11A and HBS1L-MYB genes on clinical-biological variability of sickle cell disease in a Senegalese pediatric population

Tall, F. G., Ndour, E. H. M., Djité, M., Barry, O. K., Kandji, P. M., Guéye, P. M., Cissé, A., & Sall, P. L. (2022) · African Journal of Biochemistry Research · doi:10.5897/ajbr2022.1154

Progress and development of CRISPR-Cas tool in the treatment of thalassemia

Lu, F. J., Xu, Z., & Feng, W. (2023) · Theoretical and Natural Science · doi:10.54254/2753-8818/8/20240425

Reactivate expression of fetal hemoglobin In CD34+ primary adult erythroid cells by gene therapy

Leela-adisorn, N. (2016) · doi:10.58837/chula.the.2016.1712

Differential Gene Expression Profiling during Avian Immune Organ Development: Insights from Thymus and Bursa of Fabricius Transcriptome Analysis

Goher, M. N. E. H., Moghaieb, R. E. A., Elmenawey, M. A., & Stino, F. K. R. (2024) · Journal of World s Poultry Research · doi:10.36380/jwpr.2024.4

Lymphoid origin of intrinsically activated plasmacytoid dendritic cells in micePreprint

Araujo, A. M., Dekker, J. D., Garrison, K., Su, Z., Rhee, C., Hu, Z., Lee, B., Osorio, D., Lee, J., Iyer, V. R., et al. (2024) · eLife · doi:10.7554/elife.96394.2

Proliferation and differentiation of intestinal stem cells depends on the zinc finger transcription factor BCL11/ChronophagePreprint

Redhai, S., Hirschmüller, N., Wang, T., Bahuguna, S., Leible, S., Peidli, S., Valentani, E., Kharuk, S., Holzem, M., Bräckow, L., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.09.08.611891

T and NK cell functionality in a patient harboring heterozygous novel BCL11B p.Asp632fsAla∗91 and STX11 p.R129P mutations

Erra, L., Colado, A., Brunello, F. G., Prieto, E., Goris, V., Villa, M., Oleastro, M., Marti, M. A., Pozner, R. G., Borge, M., et al. (2025) · Heliyon · doi:10.1016/j.heliyon.2025.e42636

Additional file 1 of Mild dyserythropoiesis and β-like globin gene expression imbalance due to the loss of histone chaperone ASF1B

Papadopoulos, P., Kafasi, A., Cuyper, I. M. D., Barroca, V., Lewandowski, D., Kadri, Z., Veldthuis, M., Berghuis, J., Gillemans, N., Benavente Cuesta, C. M., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13106165

Pioneer Transcription Factors Differentially Co-opt Bcl11a and Bcl11b to orchestrate ReprogrammingPreprint

Trajkova, A., Zakiev, E., Mendoza-Ferri, M. G., Messahli, I., Ruel, M., Krossa, I., Tapponnier, Y., Dejonckere, E., Hunter, E., Claret, L., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.19.694617

LDB1 represses fetal hemoglobin expression by enhancing BCL11A transcription

Park, S.-W., Choi, C., Park, I.-B., Kang, S. J., Lee, H. J., Kim, J.-I., Bae, J., Geum, D., Cheon, Y. P., & Chun, T. (2026) · Redox Biology · doi:10.1016/j.redox.2026.104070

Le suppresseur de tumeur HIC1 est une nouvelle cible directe de la kinase ATM et un acteur multifonctionnel de la réponse cellulaire aux cassures double brin (DSBs) de l’ADN

Paget, S. (2016) · theses.fr (ABES) · doi:10.70675/c8f66407zb588z4e3bzb8e5zd6af8af14d35

Nouveau mécanisme d’activation d’un oncogène impliquant RUNX1 et FUBP1 dans les leucémies aiguës lymphoblastiques

Debaize, L. (2018) · theses.fr (ABES) · doi:10.70675/d12109c7z87ccz4616zb424zdbc443e9962d

Molecular characterization and functional analysis of poor-prognosis B-cell leukemias

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Base editing approaches for the treatment of β-hemoglobinopathies

Antoniou, P. (2021) · theses.fr (ABES) · doi:10.70675/c4dddb32zf8aez4bc3z8cf8zce9a4e808265

Circadian misalignment underlies immune escape in breast cancerPreprint

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Signaling and transcriptional control of thymocyte differentiation

Taniuchi, I. (2026) · International Immunology · doi:10.1093/intimm/dxag030

Controlling Hemoglobin F Expression in Sickle Cell Disease and β-thalassemia

Popp, N. A. (2026) · Transfusion Medicine Reviews · doi:10.1016/j.tmrv.2026.150993

The Bcl11–Cxxc1 axis regulates stage-specific chromatin accessibility during lymphocyte developmentPreprint

Okuyama, K., Seo, W., Takahashi, H., Muroi, S., Hou, N., Ito, S., Sawasaki, T., Koseki, H., Wu, Y., & Taniuchi, I. (2026) · Genes & Development · doi:10.1101/gad.353082.125

Preclinical evaluation of entecavir as a fetal hemoglobin inducer using in vitro, in vivo, network pharmacology, and molecular docking approaches

Ullah, J., & Musharraf, S. G. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119901

Multiomics profiling identifies molecular and cellular signatures of regular exercise in human peripheral blood

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BCL11A-dependent redox regulation in a splenic B cell subpopulation supports erythroid recovery from anemic stress

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Bcl11a preserves hematopoietic stem cell function in culture by restraining Ncf1-dependent ROS

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The characterisation of a functional interaction between Ikaros and Foxp1 in pre-B-cells and acute lymphoblastic leukaemia

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Deletion of Bcl11a Gene Reveals Roles in Lymphoid, Myeloid, and Leukemic Cell Development.

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Bcl11a is essential for lymphoid development and negatively regulates p53

Yu, Y., Wang, J., Khaled, W. T., Burke, S., Li, P., Chen, X., Yang, W., Jenkins, N. A., Copeland, N. G., Zhang, S., et al. (2012) · The Journal of Experimental Medicine · doi:10.1084/jem.20121846 · Cited by 223

Role of the transcription factor Bcl11b in development and lymphomagenesis

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Partners in crime

Buckland, J. (2003) · Nature reviews. Immunology · doi:10.1038/nri1119

Haploinsufficiency of Bcl11b suppresses the progression of ATM-deficient T cell lymphomas

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