The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1and results in apoptosis and tumor suppression
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“p53 can transcriptionally inhibit the activity of PS1.215,216”
From p53: from understanding its structure to advances in therapeutic targeting (2026) · cites this paper as [216]
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Citations
Cites
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
Sherrington, R., Rogaev, E. I., Liang, Y., Rogaeva, E. A., Levesque, G., Ikeda, M., Chi, H., Lin, C., Li, G., Holman, K., et al. (1995) · Nature · doi:10.1038/375754a0 · Cited by 4,051
Candidate gene for the chromosome 1 familial Alzheimer’s disease locus
Levy-Lahad, E., Wasco, W., Poorkaj, P., Romano, D. M., Oshima, J., Pettingell, W. H., Yu, C.-E., Jondro, P. D., Schmidt, S. D., Wang, K., et al. (1995) · Science · doi:10.1126/science.7638622 · Cited by 2,577
Research works printed but not linked: 18
- Amson, R.B. et al. Isolation of 10 differentially expressed cDNAs in p53-induced apoptosis: Activation of the vertebrate homologue of the Drosophila seven in absentia gene. Proc. Natl. Acad. Sci. USA 93, 3953–3957 (1996). · DOI · Paper page
- Haass, C., Presenilins:Genes for life and death. Neuron 18, 687–690 (1997). · DOI
- Israeli, D. et al. A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis. EMBO J. 16, 4384–4392 (1997). · DOI · Paper page
- Yonish-Rouach, E. et al. Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature 352, 345–347 (1991). · DOI · Paper page
- Telerman, A. et al. A model for tumor suppression using H-1 parvovirus. Proc. Natl. Acad. Sci. USA 90, 8702–8706 (1993). · doi:10.1073/pnas.90.18.8702
- Nemani, M. et al. Activation of the human homologue of the Drosophila sina gene in apoptosis and tumor suppression. Proc. Natl. Acad. Sci. USA 93, 9039–9042 (1996). · doi:10.1073/pnas.93.17.9039
- El-Deiry, W.S. et al. WAF 1 a potential mediator of p53 tumor suppression. Cell 75, 817–825 (1993). · DOI · Paper page
- Michieli, P. et al. Induction of Waf1-CIP1 by a p53-independent pathway. Cancer Res. 54, 3391–3395 (1994).
- Parker, S.B. et al. p53-independent expression of p21 cip in muscle and other terminally differentiating cells. Science 267, 1724–1727 (1995). · DOI · Paper page
- Linares-Cruz, G. et al. p21Waf1 reorganizes the nucleus in tumor suppression. Proc. Natl. Acad. Sci. USA 95, 1131–1135 (1998). · DOI
- Kovacs, D.M. et al. Alzheimer-associated Presenilin 1 and 2: Neuronal expression in brain and localization to intracellular membranes in mammalian cells. Nature Med. 2, 224–229 (1996). · DOI · Paper page
- Thinakaran, G. et al. Endoproteolysis of Presenilin 1 and Accumulation of Processed derivatives in vivo. Neuron 17, 181–190 (1996). · DOI · Paper page
- Jinhe, L., Min, X., Hui, Z., Jianyi, M. & Huntington, P. Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation. Cell 90, 917–927 (1997). · DOI · Paper page
- Vito, P., Lacana, E. & D'Adiamo, L. Interfering with apoptosis: Ca2+-binding protein ALG-2 and Alzheimer's disease gene ALG-3. Science 271, 521–524 (1996). · DOI · Paper page
- Wolozin, B. et al. Participation of Presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation. Science 274, 1710–1713 (1996). · DOI · Paper page
- Kim, T.-W., Pettingell, W.H., Jung, Y.-K., Kovacs, D.M. & Tanzi, R.E. Alternative cleavage of Alzheimer-associated Presenilins during apoptosis by a caspase-3 family protease. Science 277, 373–376 (1997). · DOI · Paper page
- Shen, J. et al. Skeletal and CNS defects in Presenilin-1-deficient mice. Cell 89, 629–639 (1997). · DOI · Paper page
- Wong, Ph. C. et al. Presenilin 1 is required for Notch 1 and DII1 expression in the paraxial mesoderm. Nature 387, 288–291 (1997). · DOI · Paper page
Cited by
The Role of Oxidative Stress in Noise-Induced Hearing Loss
Henderson, D., Bielefeld, E. C., Harris, K. C., & Hu, B. H. (2006) · Ear & Hearing · doi:10.1097/01.aud.0000191942.36672.f3 · Cited by 879
The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease
Brothers, H. M., Gosztyla, M. L., & Robinson, S. R. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00118 · Cited by 314
Intracellular Aβ42 activates p53 promoter: a pathway to neurodegeneration in Alzheimer's disease
Ohyagi, Y., Asahara, H., Chui, D.-H., Tsuruta, Y., Sakae, N., Miyoshi, K., Yamada, T., Kikuchi, H., Taniwaki, T., Murai, H., et al. (2005) · The FASEB Journal · doi:10.1096/fj.04-2637fje · Cited by 281
Presenilin-1 regulates neuronal differentiation during neurogenesis
Handler, M., Yang, X., & Shent, J. (2000) · Development · doi:10.1242/dev.127.12.2593 · Cited by 225
Reciprocal down-regulation of p53 and SOD2 gene expression-implication in p53 mediated apoptosis
Drane, P., Bravard, A., Bouvard, V., & May, E. (2001) · Oncogene · doi:10.1038/sj.onc.1204101 · Cited by 180
Metadata
- Authors
- Roperch, J.-P., Alvaro, V., Prieur, S., Tuynder, M., Nemani, M., Lethrosne, F., Piouffre, L., Gendron, M.-C., Israeli, D., Dausset, J., Oren, M., Amson, R., & Telerman, A.
- Venue
- Nature Medicine
- Published
- 1998-07
- Volume
- 4
- Issue
- 7
- Pages
- 835-838
- ISSN
- 1078-8956
- 1546-170X
- Cited by
- 152
- References
- 2
- Language
- en
- Licence
- www.springer.com/tdm (tdm)
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
