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Growing tissues in microgravity
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Cites
Langer, R., & Vacanti, J. P. (1993) · Science · doi:10.1126/science.8493529 · Cited by 9,893
Principles of Tissue Engineering
(2014) · Elsevier eBooks · doi:10.1016/c2011-0-07193-4 · Cited by 1,906
TENSEGRITY: THE ARCHITECTURAL BASIS OF CELLULAR MECHANOTRANSDUCTION
Ingber, D. E. (1997) · Annual Review of Physiology · doi:10.1146/annurev.physiol.59.1.575 · Cited by 1,566
(1985) · Advances in Cancer Research · doi:10.1016/s0065-230x(08)60946-x · Cited by 1,071
Tissue Engineering by Cell Transplantation Using Degradable Polymer Substrates
Cima, L. G., Vacanti, J. P., Vacanti, C., Ingber, D., Mooney, D., & Langer, R. (1991) · Journal of Biomechanical Engineering · doi:10.1115/1.2891228 · Cited by 595
Hemodynamic forces are complex regulators of endothelial gene expression
Resnick, N., & Cimbrone, M. A. (1995) · The FASEB Journal · doi:10.1096/fasebj.9.10.7615157 · Cited by 542
Creation Of Viable Pulmonary Artery Autografts Through Tissue Engineering
Shinoka, T., Shum-Tim, D., Ma, P. X., Tanel, R. E., Isogai, N., Langer, R., Vacanti, J. P., & Mayer, J. E. (1998) · The Journal of Thoracic and Cardiovascular Surgery · doi:10.1016/s0022-5223(98)70315-0 · Cited by 444
Tissue engineering of cartilage in space
Freed, L. E., Langer, R., Martin, I., Pellis, N. R., & Vunjak-Novakovic, G. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.25.13885 · Cited by 435
Chondrogenesis in a Cell-Polymer-Bioreactor System
Freed, L. E., Hollander, A. P., Martin, I., Barry, J. R., Langer, R., & Vunjak-Novakovic, G. (1998) · Experimental Cell Research · doi:10.1006/excr.1998.4010 · Cited by 433
Schwarz, R. P., Goodwin, T. J., & Wolf, D. A. (1992) · Journal of Tissue Culture Methods · doi:10.1007/bf01404744 · Cited by 399
Cultivation of cell‐polymer cartilage implants in bioreactors
Freed, L. E., Vunjak‐Novakovic, G., & Langer, R. (1993) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240510304 · Cited by 297
Effects of Microgravity on Osteoblast Growth Activation
Hughes-Fulford, M., & Lewis, M. L. (1996) · Experimental Cell Research · doi:10.1006/excr.1996.0116 · Cited by 250
Oxygenation and differentiation in multicellular spheroids of human colon carcinoma.
Sutherland, R. M., Sordat, B., Bamat, J., Gabbert, H. E., Bourrat, B., & Mueller‐Klieser, W. (1986) · PubMed · Cited by 237
Ingram, M., Techy, G. B., Saroufeem, R., Yazan, O., Narayan, K. S., Goodwin, T. J., & Spaulding, G. F. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0064-8 · Cited by 225
Advances in tissue engineering of blood vessels and other tissues
E. Niklason, L., & S. Langer, R. (1997) · Transplant Immunology · doi:10.1016/s0966-3274(97)80013-5 · Cited by 209
Microgravity tissue engineering
Freed, L. E., & Vunjak-Novakovic, G. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0009-2 · Cited by 202
Principles of Tissue Engineering
Meesane, J. (2022) · Engineering materials · doi:10.1007/978-981-19-7830-2_2 · Cited by 136
Cell adhesion and drug resistance in cancer
Croix, B. S., & Kerbel, R. S. (1997) · Current Opinion in Oncology · doi:10.1097/00001622-199711000-00010 · Cited by 129
Jessup, J. M., Goodwin, T. J., & Spaulding, G. F. (1993) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240510308 · Cited by 113
To do tissue culture in two or three dimensions? that is the question
Hoffman, R. M. (1993) · Stem Cells · doi:10.1002/stem.5530110205 · Cited by 112
Goodwin, T. J., Schroeder, W. F., Wolf, D. A., & Moyer, M. P. (1993) · Experimental Biology and Medicine · doi:10.3181/00379727-202-43525 · Cited by 106
Tissue engineering a blood vessel: Regulation of vascular biology by mechanical stresses
Ziegler, T., & Nerem, R. M. (1994) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240560215 · Cited by 103
Cooper, D. A., & Pellis, N. R. (1998) · Journal of Leukocyte Biology · doi:10.1002/jlb.63.5.550 · Cited by 97
The distribution of protein kinase C in human leukocytes is altered in microgravity
Schmitt, D., Hatton, J. P., Emond, C., Chaput, D., Paris, H., Levade, T., Cazenave, J., & Schaffar, L. (1996) · The FASEB Journal · doi:10.1096/fasebj.10.14.9002555 · Cited by 96
Becker, J. L., Prewett, T. L., Spaulding, G. F., & Goodwin, T. J. (1993) · Journal of Cellular Biochemistry · doi:10.1002/jcb.240510307 · Cited by 91
The response of single human cells to zero gravity
Montgomery, P. O., Cook, J. E., Reynolds, R. C., Paul, J. S., Hayflick, L., Stock, D., Schulz, W., Kimsey, S., Thirolf, R. G., Rogers, T., et al. (1978) · In Vitro Cellular & Developmental Biology - Plant · doi:10.1007/bf02618218 · Cited by 88
Impact of Altered Gravity on Aspects of
Claassen, D. E., & Spooner, B. S. (1994) · International review of cytology · doi:10.1016/s0074-7696(08)62257-3 · Cited by 86
Zhau, H. E., Goodwin, T. J., Chang, S.-M., Baker, T. L., & Chung, L. W. K. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0008-3 · Cited by 84
Tissue engineering of cardiovascular structures
Mayer, J. E., Shinoka, T., & Shum‐Tim, D. (1997) · Current Opinion in Cardiology · doi:10.1097/00001573-199711000-00005 · Cited by 81
Lelkes, P. I., Galvan, D. L., Hayman, G. T., Goodwin, T. J., Chatman, D. Y., Cherian, S., Garcia, R. M. G., & Unsworth, B. R. (1998) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-998-0008-y · Cited by 80
Self-citationChanges in gravity inhibit lymphocyte locomotion through type I collagen
Pellis, N. R., Goodwin, T. J., Risin, D., McIntyre, B. W., Pizzini, R. P., Cooper, D. A., Baker, T. L., & Spaulding, G. F. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0012-7 · Cited by 79
Advances in space biology and medicine
Cogoli, A. (2002) · Elsevier eBooks · Cited by 77
Gravity Effects on Single Cells: Techniques, Findings, and Theory
Cogoli, A., & Gmünder, F. K. (1991) · Advances in space biology and medicine · doi:10.1016/s1569-2574(08)60125-2 · Cited by 72
Activation signals of T lymphocytes in microgravity
Pippia, P., Sciola, L., Cogoli‐Greuter, M., Meloni, M. A., Spano, A., & Cogoli, A. (1996) · Journal of Biotechnology · doi:10.1016/0168-1656(96)01387-9 · Cited by 71
Neonatal rat heart cells cultured in simulated microgravity
Akins, R. E., Schroedl, N. A., Gonda, S. R., & Hartzell, C. R. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0003-8 · Cited by 67
Skeletal muscle satellite cells cultured in simulated microgravity
Molnar, G., Schroedl, N. A., Gonda, S. R., & Hartzell, C. R. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0010-9 · Cited by 66
Horneck, G., Rettberg, P., Kozubek, S., Baumstark-Khan, C., Rink, H., Schäfer, M., Schmitz, C., & Schafer, M. (1997) · Radiation Research · doi:10.2307/3579347 · Cited by 63
Cell-binding Peptides Conjugated to Poly(ethylene glycol) Promote Neural Cell Aggregation
Dai, W., Belt, J., & Saltzman, W. M. (1994) · Nature Biotechnology · doi:10.1038/nbt0894-797 · Cited by 61
Movements and interactions of leukocytes in microgravity
Cogoli‐Greuter, M., Meloni, M. A., Sciola, L., Spano, A., Pippia, P., Monaco, G., & Cogoli, A. (1996) · Journal of Biotechnology · doi:10.1016/0168-1656(96)01380-6 · Cited by 53
Moreira, J. L., Santana, P. C., Feliciano, A. S., Cruz, P. E., Racher, A. J., Griffiths, J. B., & Carrondo, M. J. T. (1995) · Biotechnology Progress · doi:10.1021/bp00035a012 · Cited by 53
Three-dimensional endothelial-tumor epithelial cell interactions in human cervical cancers
Chopra, V., Dinh, T., & Hannigan, E. V. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0061-y · Cited by 51
Development of a miniature bioreactor for continuous culture in a space laboratory
Walther, I., van der Schoot, B. H., Jeanneret, S., Arquint, P., de Rooij, N. F., Gass, V., Bechler, B., Lorenzi, G., & Cogoli, A. (1994) · Journal of Biotechnology · doi:10.1016/0168-1656(94)90144-9 · Cited by 49
TISSUE ENGINEERING IN UROLOGIC SURGERY
Atala, A. (1998) · Urologic Clinics of North America · doi:10.1016/s0094-0143(05)70431-6 · Cited by 48
Goodwin, T. J., Prewett, T. L., Spaulding, G. F., & Becker, J. L. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0007-4 · Cited by 48
Induction of carcinoembryonic antigen expression in a three-dimensional culture system
Jessup, J. M., Brown, D., Fitzgerald, W., Ford, R., Nachman, A., Goodwin, T. J., & Spaulding, G. F. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0005-6 · Cited by 41
Margolis, L. B., Fitzgerald, W., Glushakova, S. E., Hatfill, S. J., AMICHAY, N., Baibakov, B. A., & Zimmerberg, J. J. (1997) · AIDS Research and Human Retroviruses · doi:10.1089/aid.1997.13.1411 · Cited by 38
Schuster, U., Büttner, R., Hofstädter, F., et al. (1994) · The Journal of Urology · doi:10.1016/s0022-5347(17)35349-1 · Cited by 30
Multicellular tumor spheroids in radiotherapy research (review).
Jh, S. (1990) · PubMed · Cited by 29
The three-dimensional question: can clinically relevant tumor drug resistance be measuredin vitro?
Hoffman, R. M. (1994) · Cancer and Metastasis Reviews · doi:10.1007/bf00689634 · Cited by 28
Rhinovirus replication in HeLa cells cultured under conditions of simulated microgravity.
Long, J. P., Pierson, S., & Jh, H. (1998) · PubMed · Cited by 26
Becker, J. L., Papenhausen, P. R., & Widen, R. H. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0001-x · Cited by 24
O’Connor, K. C., Enmon, R. M., Dotson, R. S., Primavera, A. C., & Clejan, S. (1997) · Tissue Engineering · doi:10.1089/ten.1997.3.161 · Cited by 17
Cultivation of fall armyworm ovary cells in simulated microgravity
Francis, K. M., O’Connor, K. C., & Spaulding, G. F. (1997) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-997-0002-9 · Cited by 16
Krewson, C. E., & Saltzman, W. M. (1996) · Tissue Engineering · doi:10.1089/ten.1996.2.183 · Cited by 14
Weaving cartilage at zero g : the reality of tissue engineering in space
Saltzman, W. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.25.13380 · Cited by 13
Cited by
Recent advances in three‐dimensional multicellular spheroid culture for biomedical research
Lin, R., & Chang, H. (2008) · Biotechnology Journal · doi:10.1002/biot.200700228 · Cited by 1,264
Vinci, M., Gowan, S., Boxall, F., Patterson, L., Zimmermann, M., Court, W., Lomas, C., Mendiola, M., Hardisson, D., & Eccles, S. A. (2012) · BMC Biology · doi:10.1186/1741-7007-10-29 · Cited by 1,024
Three-Dimensional Cell Culture: A Breakthrough in Vivo
Antoni, D., Burckel, H., Josset, E., & Noel, G. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms16035517 · Cited by 990
The use of 3-d cultures for high-throughput screening: the multicellular spheroid model.
Kunz-Schughart, L. A., Freyer, J. P., Hofstaedter, F., & Ebner, R. (2004) · SLAS DISCOVERY · doi:10.1177/1087057104265040 · Cited by 797
Three-dimensional tissue culture models in cancer biology
Kim, J. B. (2005) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2005.05.002 · Cited by 613
Metadata
- Authors
- Unsworth, B. R., & Lelkes, P. I.
- Venue
- Nature Medicine
- Published
- 1998-08
- Volume
- 4
- Issue
- 8
- Pages
- 901-907
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W1999487669
- Cited by
- 393
- References
- 55
- FWCI
- 6.42
- Type
- journal article
- Language
- en
- Open access
- closed
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