Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides

Koistinaho, Milla, Lin, Suizhen, Wu, Xin, Esterman, Michail, Koger, Deanna, Hanson, Jeffrey, Higgs, Richard, Liu, Feng +3 more·2004·Nature Medicine

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Items 101–200 of 569

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  2. Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: Involvement of oxidative stress and mitogen-activated protein kinase cascades
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  8. Neuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's disease
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  9. Metabolism of amyloid-β peptide and Alzheimer's disease
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  13. Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins
    Huynh, Tien-Phat V., Davis, Albert A., Ulrich, Jason D., Holtzman, David M. · 2017 · Journal of Lipid Research
  14. Gene delivery of human apolipoprotein E alters brain Aβ burden in a mouse model of Alzheimer's disease
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  16. Apolipoproteins in the brain: implications for neurological and psychiatric disorders
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  17. Low-density Lipoprotein Receptor Represents an Apolipoprotein E-independent Pathway of Aβ Uptake and Degradation by Astrocytes
    Basak, Jacob M., Verghese, Philip B., Yoon, Hyejin, Kim, Jungsu, Holtzman, David M. · 2012 · Journal of Biological Chemistry
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    Cody M. Wolfe, Nicholas Francis Fitz, Kyong Nyon Nam, Iliya M. Lefterov, Radosveta P. Koldamova · 2018 · International Journal of Molecular Sciences
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    Chua, Jason P., De Calbiac, Hortense, Kabashi, Edor, Barmada, Sami J. · 2022 · Autophagy
  20. Microarray analysis of the astrocyte transcriptome in the aging brain: relationship to Alzheimer’s pathology and APOE genotype
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    Giulia Paroni, Paola Bisceglia, Davide Seripa · 2019 · Journal of Alzheimer s Disease
  22. Apolipoprotein E4, inhibitory network dysfunction, and Alzheimer’s disease
    Najm, Ramsey, Jones, Emily A., Huang, Yadong · 2019 · Molecular Neurodegeneration
  23. Apolipoprotein E Modulates Clearance of Apoptotic Bodies In Vitro and In Vivo, Resulting in a Systemic Proinflammatory State in Apolipoprotein E-Deficient Mice
    Grainger, David J, Reckless, Jill, McKilligin, Elaine · 2004 · The Journal of Immunology
  24. Lipid homeostasis and apolipoprotein E in the development and progression of Alzheimer's disease
    Roger M. Lane, Martin Rhys Farlow · 2005 · Journal of Lipid Research
  25. Protein aggregate spreading in neurodegenerative diseases: Problems and perspectives
    Seung‐Jae Lee, Hee-Sun Lim, Eliezer Masliah, He-Jin Lee · 2011 · Neuroscience Research
  26. Neprilysin-sensitive Synapse-associated Amyloid-β Peptide Oligomers Impair Neuronal Plasticity and Cognitive Function
    Shu-Ming Huang, Akihiro Mouri, Hideko Kokubo, Ryuichi Nakajima, Takahiro Suemoto, Makoto Higuchi, Matthias Staufenbiel, Yukihiro Noda, Haruyasu Yamaguchi, Toshitaka Nabeshima et al. · 2006 · Journal of Biological Chemistry
  27. Astrocyte physiopathology: At the crossroads of intercellular networking, inflammation and cell death
    Daniela Rossi · 2015 · Progress in Neurobiology
  28. Reducing Human Apolipoprotein E Levels Attenuates Age-Dependent Aβ Accumulation in Mutant Human Amyloid Precursor Protein Transgenic Mice
    Bien-Ly, Nga, Gillespie, Anna K., Walker, David, Yoon, Seo Yeon, Huang, Yadong · 2012 · The Journal of Neuroscience
  29. Amyloid Deposition and Inflammation in APPswe/PS1dE9 Mouse Model of Alzheimers Disease
    Lingfei Ruan, Zhoujun Kang, Gang Pei, Yingying Le · 2009 · Current Alzheimer Research
  30. Levels of Soluble Apolipoprotein E/Amyloid-β (Aβ) Complex Are Reduced and Oligomeric Aβ Increased with APOE4 and Alzheimer Disease in a Transgenic Mouse Model and Human Samples*
    Tai, Leon M., Bilousova, Tina, Jungbauer, Lisa, Roeske, Stephen K., Youmans, Katherine L., Yu, Chunjiang, Poon, Wayne W., Cornwell, Lindsey B., Miller, Carol A., Vinters, Harry V. et al. · 2013 · Journal of Biological Chemistry
  31. The roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer disease
    Naoyuki Sato, Ryuichi Morishita · 2015 · Frontiers in Aging Neuroscience
  32. Astrocytic Aβ1‐42 uptake is determined by Aβ‐aggregation state and the presence of amyloid‐associated proteins
    Henrietta M. Nielsen, Sandra D. Mulder, Jeroen A.M. Beliën, René J.P. Musters, Piet Eikelenboom, Robert Veerhuis · 2010 · Glia
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    Benjamin Troutwine, Laylan Hamid, Colton R Lysaker, Taylor A. Strope, Heather Wilkins · 2021 · Acta Pharmaceutica Sinica B
  34. Transplanted astrocytes internalize deposited β‐amyloid peptides in a transgenic mouse model of Alzheimer's disease
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    Lee, Jee Hoon, Park, Sang Myun, Kim, Ohn Soon, Lee, Chang Seok, Woo, Joo Hong, Park, Soo Jung, Joe, Eun-hye, Jou, Ilo · 2009 · Molecular Cell
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    Alexei Verkhratsky, Vladimir Parpura, Marcela Pekna, Milos Pekny, Michael V. Sofroniew · 2014 · Biochemical Society Transactions
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    S. Vesce, D. Rossi, L. Brambilla, A. Volterra · 2007 · International review of neurobiology
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    Zhao, Ruohe, Hu, Wanling, Tsai, Julia, Li, Wei, Gan, Wen-Biao · 2017 · Molecular Neurodegeneration
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    Angela R. Filous, Jerry Silver · 2016 · Progress in Neurobiology
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    Md. Sahab Uddin, Lee Wei Lim · 2022 · Ageing Research Reviews
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    Milla Koistinaho, Jari Koıstınaho · 2005 · Brain Research Reviews
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    Marius Krauthausen, Markus P. Kummer, Julian Zimmermann, Elisabet Reyes-Irisarri, Dick Terwel, Bruno Bulic, Michael Thomas Heneka, Marcus Müller · 2014 · Journal of Clinical Investigation
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    Abhay P. Sagare, Robert D. Bell, Berislav V. Zloković · 2012 · Journal of Alzheimer s Disease
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    Abhay P. Sagare, Rashid Deane, Berislav V. Zloković · 2012 · Pharmacology & Therapeutics
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    Hervé Rhinn, Ryousuke Fujita, Liang Qiang, Rong Cheng, Joseph Hyungwoo Lee, Asa Abeliovich · 2013 · Nature · Retracted
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    Dietmar Rudolf Thal · 2012 · Experimental Neurology
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    Lauren M. Billings, Kim N. Green, James Lafayette McGaugh, Frank M. LaFerla · 2007 · Journal of Neuroscience
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    Masayuki Morikawa, John Denis Fryer, Patrick M. Sullivan, Erin Christopher, Suzanne E. Schindler, Ronald Bradley Demattos, Mark Odell, Anne M. Fagan, Hilal Ahmed Lashuel, Thomas Walz et al. · 2005 · Neurobiology of Disease
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    Liu, Cai-Yun, Yang, Yu, Ju, Wei-Na, Wang, Xu, Zhang, Hong-Liang · 2018 · Frontiers in Cellular Neuroscience
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  80. The impact of glial activation in the aging brain.
    Aileen M. Lynch, Kevin J Murphy, Brian F. Deighan, Julie-Ann O’Reilly, Yurii K. Gun’ko, Thelma R. Cowley, Rodrigo E. González-Reyes, Marina A. Lynch · 2010 · Europe PMC (PubMed Central)
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  87. Apolipoprotein E, amyloid-beta, and neuroinflammation in Alzheimer’s disease
    Evan Dorey, Nina Chang, Qing Yan Liu, Ze Yang, Wandong Zhang · 2014 · Neuroscience Bulletin
  88. Human intravenous immunoglobulin provides protection against Aβ toxicity by multiple mechanisms in a mouse model of Alzheimer's disease
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  92. Binding and uptake of Aβ1‐42 by primary human astrocytes <i>in vitro</i>
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  95. Lipid metabolism and neuroinflammation in Alzheimer’s disease: a role for liver X receptors
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  98. Amyloids: Friend or Foe?
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