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A Growing Link between Circadian Rhythms, Type 2 Diabetes Mellitus and Alzheimer’s Disease

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Role of Receptors in Relation to Plaques and Tangles in Alzheimer’s Disease Pathology

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sc2GWAS: a comprehensive platform linking single cell and GWAS traits of human

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Multi-omic analysis of Huntington’s disease reveals a compensatory astrocyte state

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Microglia in Alzheimer's Disease: a Key Player in the Transition Between Homeostasis and Pathogenesis

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Blood Astrocyte Biomarkers in Alzheimer Disease

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Neuroinflammatory Proteins in Huntington’s Disease: Insights into Mechanisms, Diagnosis, and Therapeutic Implications

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Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer’s disease

Xie, Z., Meng, J., Kong, W., Wu, Z., Lan, F., Narengaowa, Hayashi, Y., Yang, Q., Bai, Z., Nakanishi, H., et al. (2022) · Aging Cell · doi:10.1111/acel.13565 · Cited by 31 · see citing works

Deciphering clock genes as emerging targets against aging

Zhu, Y., Liu, Y., Escames, G., Yang, Z. Z., Zhao, H., Lu, Q., Xue, C., Xu, D., Acuña-Castroviejo, D., & Yang, Y. (2022) · Ageing Research Reviews · doi:10.1016/j.arr.2022.101725 · Cited by 31 · see citing works

Advances in the Understanding of the Correlation Between Neuroinflammation and Microglia in Alzheimer’s Disease

Yan, H., Wang, W., Cui, T., Shao, Y., Li, M., Fang, L., & Feng, L. (2024) · ImmunoTargets and Therapy · doi:10.2147/itt.s455881 · Cited by 30 · see citing works

A glial circadian gene expression atlas reveals cell-type and disease-specific reprogramming in response to amyloid pathology or aging

Sheehan, P. W., Fass, S. B., Sapkota, D., Kang, S., Hollis, H. C., Lawrence, J. H., Park, S., Sharma, A., Schafer, D. P., Anafi, R. C., et al. (2025) · Nature Neuroscience · doi:10.1038/s41593-025-02067-1 · Cited by 30 · see citing works

Potential Roles and Future Perspectives of Chitinase 3-like 1 in Macrophage Polarization and the Development of Diseases

Zhao, H., Huang, M., & Jiang, L. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242216149 · Cited by 30 · see citing works

Association of Plasma YKL-40 With MRI, CSF, and Cognitive Markers of Brain Health and Dementia

Pase, M. P., Himali, J. J., Puerta, R., Beiser, A., Gonzales, M. M., Satizábal, C. L., Yang, Q., Aparicio, H. J., Kojis, D. J., DeCarli, C. S., et al. (2024) · Neurology · doi:10.1212/wnl.0000000000208075 · Cited by 29 · see citing works

Circadian Clock-Controlled Checkpoints in the Pathogenesis of Complex Disease

Li, M., Xin, H., Yuan, Y., Yang, X., Li, H., Tian, D., Zhang, H., Zhang, Z., Han, T.-L., Chen, Q., et al. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.721231 · Cited by 29 · see citing works

Gut microbiota–astrocyte axis: new insights into age-related cognitive decline

Zhang, L., Wei, J., Liu, X., Li, D., Pang, X., Chen, F., Cao, H., & Lei, P. (2024) · Neural Regeneration Research · doi:10.4103/nrr.nrr-d-23-01776 · Cited by 28 · see citing works

Astrocyte-specific knockout of YKL-40/Chi3l1 reduces Aβ burden and restores memory functions in 5xFAD mice

Zeng, X., Cheung, S. K. K., Shi, M., Or, P. M. Y., Li, Z., Liu, J. Y. H., Ho, W. L.-H., Liu, T., Lu, K., Rudd, J. A., et al. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02970-z · Cited by 27 · see citing works

TREM2, Driving the Microglial Polarization, Has a TLR4 Sensitivity Profile After Subarachnoid Hemorrhage

Hu, Y., Li, C., Wang, X., Chen, W., Yu, Q., & Dai, X. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.693342 · Cited by 27 · see citing works

Identification of hub proteins in cerebrospinal fluid as potential biomarkers of Alzheimer’s disease by integrated bioinformatics

Li, Y., Chen, Z., Wang, Q., Lv, X., Cheng, Z., Wu, Y., Tang, F., Shen, Y., & Gao, F. (2022) · Journal of Neurology · doi:10.1007/s00415-022-11476-2 · Cited by 27 · see citing works

Myeloid-specific deletion of chitinase-3-like 1 protein ameliorates murine diet-induced steatohepatitis progression

Kim, A. D., Kui, L., Kaufmann, B. K., Kim, S. E., Leszczynska, A., & Feldstein, A. E. (2023) · Journal of Molecular Medicine · doi:10.1007/s00109-023-02325-4 · Cited by 27 · see citing works

Pterostilbene participates in TLR4- mediated inflammatory response and autophagy-dependent Aβ1–42 endocytosis in Alzheimer's disease

Xu, J., Liu, J., Li, Q., Li, G., Zhang, G., Mi, Y., Zhao, T., Mu, D., Wang, D., Zeng, K., et al. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.155011 · Cited by 26 · see citing works

Molecules of senescent glial cells differentiate Alzheimer’s disease from ageing

Dai, L., Gao, F., Wang, Q., Lv, X., Cheng, Z., Wu, Y., Chai, X., Zetterberg, H., Blennow, K., Levey, A. I., et al. (2023) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2022-330743 · Cited by 25 · see citing works

Peripheral Blood and Cerebrospinal Fluid Levels of YKL-40 in Alzheimer’s Disease: A Systematic Review and Meta-Analysis

Zhang, Y., Tian, J., Ni, J., Wei, M., Li, T., & Shi, J. (2023) · Brain Sciences · doi:10.3390/brainsci13101364 · Cited by 25 · see citing works

The challenges of anti-tau therapeutics in Alzheimer disease

Panza, F., & Lozupone, M. (2022) · Nature Reviews Neurology · doi:10.1038/s41582-022-00702-0 · Cited by 23 · see citing works

Recently Updated Role of Chitinase 3-like 1 on Various Cell Types as a Major Influencer of Chronic Inflammation

Mizoguchi, E., Sadanaga, T., Nanni, L., Wang, S., & Mizoguchi, A. (2024) · Cells · doi:10.3390/cells13080678 · Cited by 23 · see citing works

Clinical development of passive tau-based immunotherapeutics for treating primary and secondary tauopathies

Panza, F., Dibello, V., Sardone, R., Castellana, F., Zupo, R., Lampignano, L., Bortone, I., Stallone, R., Cirillo, N., Damiani, C., et al. (2023) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2023.2233892 · Cited by 22 · see citing works

Spatial transcriptomics at the brain-electrode interface in rat motor cortex and the relationship to recording quality

Whitsitt, Q. A., Saxena, A., Patel, B., Evans, B. M., Hunt, B., & Purcell, E. K. (2024) · Journal of Neural Engineering · doi:10.1088/1741-2552/ad5936 · Cited by 22 · see citing works

Innate and adaptive immunity in neurodegenerative disease

Huang, Y., Zhang, G., Li, S., Feng, J., & Zhang, Z. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05533-4 · Cited by 21 · see citing works

Neuronal and glial vulnerability of the suprachiasmatic nucleus in tauopathies: evidence from human studies and animal models

Son, G., Neylan, T. C., & Grinberg, L. T. (2024) · Molecular Neurodegeneration · doi:10.1186/s13024-023-00695-4 · Cited by 21 · see citing works

Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease

Nordengen, K., Kirsebom, B., Richter, G., Pålhaugen, L., Gísladóttir, B., Siafarikas, N., Nakling, A. E., Rongve, A., Bråthen, G., Grøntvedt, G. R., et al. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02973-w · Cited by 20 · see citing works

Circadian regulation of microglia function: Potential targets for treatment of Parkinson’s Disease

Kou, L., Chi, X., Sun, Y., Yin, S., Wu, J., Zou, W., Wang, Y., Jin, Z., Huang, J., Xiong, N., et al. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102232 · Cited by 20 · see citing works

Inflammatory Effects and Regulatory Mechanisms of Chitinase-3-like-1 in Multiple Human Body Systems: A Comprehensive Review

Liu, D., Hu, X., Ding, X., Li, M., & Ding, L. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252413437 · Cited by 20 · see citing works

Near-infrared light reduces glia activation and modulates neuroinflammation in the brains of diet-induced obese mice

Saieva, S., & Taglialatela, G. (2022) · Scientific Reports · doi:10.1038/s41598-022-14812-8 · Cited by 19 · see citing works

Therapeutic Implications of Probiotics in the Gut Microbe-Modulated Neuroinflammation and Progression of Alzheimer’s Disease

Murai, T., & Matsuda, S. (2023) · Life · doi:10.3390/life13071466 · Cited by 19 · see citing works

Dietary emulsifier polysorbate 80 exposure accelerates age-related cognitive decline

Zhang, L., Yin, Z., Liu, X., Jin, G., Wang, Y., He, L., Li, M., Pang, X., Yan, B., Jia, Z.-X., et al. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.03.052 · Cited by 19 · see citing works

Adenosine A2A Receptor Suppressed Astrocyte-Mediated Inflammation Through the Inhibition of STAT3/YKL-40 Axis in Mice With Chronic Cerebral Hypoperfusion-induced White Matter Lesions

Yuan, J., Chen, L., Wang, J., Xia, S., Huang, J., Zhou, L., Feng, C., Hu, X., Zhou, Z., & Ran, H. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.841290 · Cited by 19 · see citing works

Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways

Ibanez, K. R., McFarland, K. N., Phillips, J., Allen, M., Lessard, C. B., Zobel, L., De La Cruz, E. G., Shah, S., Vo, Q., Wang, X., et al. (2022) · Alzheimer's Research &amp; Therapy · doi:10.1186/s13195-022-01044-1 · Cited by 18 · see citing works

Associations between accelerometer‐measured circadian rest‐activity rhythm, brain structural and genetic mechanisms, and dementia

Liu, Y., Feng, H., Du, J., Yang, L., Xue, H., Zhang, J., Liang, Y. Y., & Liu, Y. (2024) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13671 · Cited by 18 · see citing works

Targeting and reprogramming microglial phagocytosis of neutrophils by ginsenoside Rg1 nanovesicles promotes stroke recovery

Hu, K., Ye, J.-R., Fan, P., Zheng, R., Wang, S., Peng, Y., Ruan, Y., Xu, Y., Zhang, Z., Chu, S., et al. (2025) · Bioactive Materials · doi:10.1016/j.bioactmat.2025.01.017 · Cited by 18 · see citing works

The role of astrocytes in generating circadian rhythmicity in health and disease

Costa, R., & Montagnese, S. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15312 · Cited by 18 · see citing works

Prevention and Treatment of Alzheimer's Disease Via the Regulation of the Gut Microbiota With Traditional Chinese Medicine

Long, J., Zhang, J., Zeng, X., Wang, M., & Wang, N. (2024) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.70101 · Cited by 17 · see citing works

Passive tau-based immunotherapy for tauopathies

Panza, F., Solfrizzi, V., Daniele, A., & Lozupone, M. (2023) · Handbook of clinical neurology · doi:10.1016/b978-0-323-98817-9.00029-6 · Cited by 17 · see citing works

Neurosyphilis is characterized by a compartmentalized and robust neuroimmune response but not by neuronal injury

Catalano, A. A., Yoon, J., Fertuzinhos, S., Reisert, H. D., Walsh, H. L., Kosana, P., Wilson, M. R., Gisslén, M., Zetterberg, H., Marra, C. M., et al. (2024) · Med · doi:10.1016/j.medj.2024.02.005 · Cited by 17 · see citing works

CHI3L1/YKL-40 signaling inhibits neurogenesis in models of Alzheimer’s disease

Yang, X., Jiang, W., Li, Y., Lee, C. G., Elias, J. A., Tang, C., & Huang, Y. A. (2025) · Science Advances · doi:10.1126/sciadv.adv1492 · Cited by 16 · see citing works

Single-cell transcriptome reveals Staphylococcus aureus modulating fibroblast differentiation in the bone-implant interface

Yu, J., Wang, B., Zhang, F., Ren, Z., Jiang, F., Hamushan, M., Li, M., Guo, G., & Shen, H. (2023) · Molecular Medicine · doi:10.1186/s10020-023-00632-7 · Cited by 16 · see citing works

Exploring Astrocyte-Mediated Mechanisms in Sleep Disorders and Comorbidity

Li, Y., Que, M., Wang, X., Zhan, G., Zhou, Z., Luo, X., & Li, S. (2023) · Biomedicines · doi:10.3390/biomedicines11092476 · Cited by 16 · see citing works

Activity and Heterogeneity of Astrocytes in Neurological Diseases: Molecular Mechanisms and Therapeutic Targets

Mao, S., Qiao, R., Wang, Q., Shen, L., Li, D., Huo, X., Wang, J., Liu, K., Chen, W., Zhu, T., et al. (2025) · MedComm · doi:10.1002/mco2.70329 · Cited by 15 · see citing works

Perivascular glial reactivity is a feature of phosphorylated tau lesions in chronic traumatic encephalopathy

Osterman, C., Hamlin, D., Suter, C. M., Affleck, A. J., Gloss, B., Turner, C. P., Faull, R. L. M., Stein, T. D., McKee, A. C., Buckland, M. E., et al. (2025) · Acta Neuropathologica · doi:10.1007/s00401-025-02854-x · Cited by 15 · see citing works

YKL-40 changes are not detected in post-mortem brain of patients with Alzheimer’s disease and frontotemporal lobar degeneration

Hok‐A‐Hin, Y. S., Hoozemans, J. J. M., Hu, W. T., Wouters, D., Howell, J. C., Rábano, A., van der Flier, W. M., Pijnenburg, Y. A. L., Teunissen, C. E., & del Campo, M. (2022) · Alzheimer s Research & Therapy · doi:10.1186/s13195-022-01039-y · Cited by 15 · see citing works

Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid

Hou, X., Qiu, Y., Li, H., Yan, Y., Zhao, D., Ji, S., Ni, J., Zhang, J., Liu, K., Qing, H., et al. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01789-5 · Cited by 14 · see citing works

The transcriptional repressor Rev-erbα regulates circadian expression of the astrocyte Fabp7 mRNA

Vanderheyden, W. M., Fang, B., Flores, C. C., Jager, J., & Gerstner, J. R. (2021) · Current Research in Neurobiology · doi:10.1016/j.crneur.2021.100009 · Cited by 14 · see citing works

Role of circadian rhythms in pathogenesis of acute CNS injuries: Insights from experimental studies

Hetman, M., Słomnicki, Ł. P., Hodges, E. R., Ohri, S. S., & Whittemore, S. R. (2022) · Experimental Neurology · doi:10.1016/j.expneurol.2022.114080 · Cited by 14 · see citing works

The Relationships between Cerebrospinal Fluid Glial (CXCL12, CX3CL, YKL-40) and Synaptic Biomarkers (Ng, NPTXR) in Early Alzheimer’s Disease

Kulczyńska‐Przybik, A., Dulewicz, M., Doroszkiewicz, J., Borawska, R., Słowik, A., Zetterberg, H., Hanrieder, J., Blennow, K., & Mroczko, B. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713166 · Cited by 14 · see citing works

Neuroinflammation-mediated YKL-40 correlates with tau pathology and predicts longitudinal cognitive impairment and brain atrophy in Alzheimer’s disease, with hypertensive dependency

Wang, Y., Zhang, M., Chen, S.-J., Miao, W., Wang, Z., Zhou, Y., Yu, S., Sun, Z., Zhou, X., Yu, X., et al. (2025) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2025.1630022 · Cited by 13 · see citing works

The Role of Mesenchymal Stem Cells in Regulating Astrocytes-Related Synapse Dysfunction in Early Alzheimer’s Disease

Liu, C. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.927256 · Cited by 13 · see citing works

Potential of astrocytes in targeting therapy for Alzheimer’s disease

Bi, W., Lei, T., Cai, S., Zhang, X., Yang, Y., Xiao, Z., Wang, L., & Du, H. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109368 · Cited by 13 · see citing works

Astrocyte Circadian Timekeeping in Brain Health and Neurodegeneration

Brancaccio, M., Wolfes, A. C., & Ness, N. (2021) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-81147-1_6 · Cited by 12 · see citing works

E3 ubiquitin ligase UBR5 modulates circadian rhythm by facilitating the ubiquitination and degradation of the key clock transcription factor BMAL1

Duan, C.-Y., Li, Y., Zhi, H.-Y., Tian, Y., Huang, Z., Chen, S., Zhang, Y., Liu, Q. L., Zhou, L., Jiang, X., et al. (2024) · Acta Pharmacologica Sinica · doi:10.1038/s41401-024-01290-z · Cited by 11 · see citing works

Ticking Brain: Circadian Rhythm as a New Target for Cerebroprotection

Xu, S., Jia, M., Guo, J., He, J., Chen, X., Xu, Y., Hu, W., Wu, D., Wu, C., & Ji, X. (2024) · Stroke · doi:10.1161/strokeaha.124.046684 · Cited by 11 · see citing works

Functional Specificity of Astrocyte Subtypes in Alzheimer’s Disease: Decoding Disease Mechanisms Through Network-based Analysis of Integrated Single-Nuclei Multi-Omic Data

İlgün, A., & Çakır, T. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04965-8 · Cited by 11 · see citing works

A sex-stratified analysis of neuroimmune gene expression signatures in Alzheimer’s disease brains

Sanfilippo, C., Castrogiovanni, P., Vinciguerra, M., Imbesi, R., Ulivieri, M., Fazio, F., Blennow, K., Zetterberg, H., & Rosa, M. D. (2022) · GeroScience · doi:10.1007/s11357-022-00664-7 · Cited by 11 · see citing works

Conserved YKL-40 changes in mice and humans after postoperative delirium

David‐Bercholz, J., Acker, L., Caceres, A. I., Wu, P. Y., Goenka, S., Franklin, N. O., Rodriguiz, R. M., Wetsel, W. C., Devinney, M. J., Cooter, M. L., et al. (2022) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2022.100555 · Cited by 11 · see citing works

Chromatin target of protein arginine methyltransferases alleviates cerebral ischemia/reperfusion-induced injury by regulating RNA alternative splicing

Cui, Y., Zhang, Z., Lv, M., Duan, Z., Liu, W., Gao, J., Xu, R., & Wan, Q. (2023) · iScience · doi:10.1016/j.isci.2023.108688 · Cited by 11 · see citing works

Astrocyte Reactivity in Alzheimer’s Disease: Therapeutic Opportunities to Promote Repair

Mirzaei, N., Davis, N., Chau, T. W., & Sastre, M. (2021) · Current Alzheimer Research · doi:10.2174/1567205018666211029164106 · Cited by 11 · see citing works

Exploring SERPINA3 as a neuroinflammatory modulator in Alzheimer’s disease with sex and regional brain variations

Sanfilippo, C., Castrogiovanni, P., Imbesi, R., Vecchio, M. M., Sortino, M., Musumeci, G., Vinciguerra, M., & Rosa, M. D. (2025) · Metabolic Brain Disease · doi:10.1007/s11011-024-01523-4 · Cited by 10 · see citing works

Research progress on the role and mechanism of circadian clock gene PER1 in the occurrence and development of multiple diseases

Zhao, Y., Li, Y., Lu, T., Huang, X., Chen, K., Tan, L., & Gao, L. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1715457 · Cited by 10 · see citing works

Astrocytic circadian clock control of energy expenditure by transcriptional stress responses in the ventromedial hypothalamus

Mendoza-Viveros, L., Marmolejo‐Gutierrez, C., Cid‐Castro, C., Escalante‐Covarrubias, Q., Montellier, E., Carreño‐Vázquez, E., Noriega, L. G., Velázquez‐Villegas, L. A., Tovar, A. R., Sassone‐Corsi, P., et al. (2023) · Glia · doi:10.1002/glia.24360 · Cited by 10 · see citing works

Targeted ASO-mediated Atp1a2 knockdown in astrocytes reduces SOD1 aggregation and accelerates disease onset in mutant SOD1 mice

Iyer, A. K., Schoch, K. M., Verbeck, A. C., Galasso, G., Chen, H., Smith, S. E., Oldenborg, A., Miller, T. M., Karch, C. M. M., & Bonni, A. (2023) · PLoS ONE · doi:10.1371/journal.pone.0294731 · Cited by 9 · see citing works

Excitatory Neurons Derived from Human-Induced Pluripotent Stem Cells Show Transcriptomic Differences in Alzheimer’s Patients from Controls

Sagar, R., Azoidis, I., Zivko, C., Xydia, A., Oh, E. S., Rosenberg, P. B., Lyketsos, C. G., Mahairaki, V., & Avramopoulos, D. (2023) · Cells · doi:10.3390/cells12151990 · Cited by 9 · see citing works

Astrocytic Ephrin-B1 Regulates Oligodendrocyte Development and Myelination

Sutley-Koury, S. N., Anderson, A., Taitano-Johnson, C., Ajayi, M. T., Kulinich, A. O., Contreras, K., Regalado, J., Tiwari-Woodruff, S. K., & Ethell, I. M. (2024) · ASN NEURO · doi:10.1080/17590914.2024.2401753 · Cited by 8 · see citing works

Advances of therapeutic strategies for Alzheimer’s disease

Guo, X., Yue, R.-Z., Cui, Z., Wang, S., Jia, T., Li, W., Zhang, W., Shan, L., & Li, C. (2025) · Journal of Neurology · doi:10.1007/s00415-025-13456-8 · Cited by 8 · see citing works

Sexually dimorphic role of circadian clock genes in alcohol drinking behavior

de Zavalía, N., Ferraro, S., & Amir, S. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06247-w · Cited by 8 · see citing works

The signaling function of CHI3L1/YKL‐40 in neuroinflammation and Alzheimer’s disease

Huang, Y. A. (2024) · Alzheimer s & Dementia · doi:10.1002/alz.085972

The Degenerating Star Clock: Circadian Clock Regulation of Astrogliosis and Implications for Alzheimer’s Disease

Lananna, B. V. (2019) · Open Scholarship Institutional Repository (Washington University in St. Louis) · doi:10.7936/eds6-a918

Potential role of chitinase‐3‐like protein 1 (CHI3L1/YKL‐40) in neurodegeneration and Alzheimer's disease

Connolly, K., Lehoux, M., O’Rourke, R., Assetta, B., Erdemir, G. A., Elias, J. A., Lee, C. G., & Huang, Y. A. (2022) · Alzheimer s & Dementia · doi:10.1002/alz.12612 · Cited by 142 · see citing works

Astrocyte-specific knockout of YKL-40/Chi3l1 reduces Aβ burden and restores memory functions in 5xFAD mice

Zeng, X., Cheung, S. K. K., Shi, M., Or, P. M. Y., Li, Z., Liu, J. Y. H., Ho, W. L.-H., Liu, T., Lu, K., Rudd, J. A., et al. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02970-z · Cited by 27 · see citing works

YKL-40 (Chitinase 3-like I) is expressed in a subset of astrocytes in Alzheimer’s disease and other tauopathies

Querol‐Vilaseca, M., Colom‐Cadena, M., Pegueroles, J., Martín-Paniello, C. S., Clarimón, J., Belbin, O., Fortea, J., & Lleó, A. (2017) · Figshare · doi:10.6084/m9.figshare.c.3800161