Soluble endoglin contributes to the pathogenesis of preeclampsia

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

Maynard, S. E., Min, J.-Y., Merchan, J., Lim, K.-H., Li, J., Mondal, S., Libermann, T. A., Morgan, J. P., Sellke, F. W., Stillman, I. E., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci17189 · Cited by 4,101 · see citing works

Circulating angiogenic factors and the risk of preeclampsia

Levine, R. J., Maynard, S. E., Qian, C., Lim, K.-H., England, L. J., Yu, K. F., Schisterman, E. F., Thadhani, R., Sachs, B. P., Epstein, F. H., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa031884 · Cited by 3,720 · see citing works

Circulating angiogenic factors and the risk of preeclampsia*

(2004) · Obstetrics and Gynecology · doi:10.1097/00006250-200405000-00028 · Cited by 2,623 · see citing works

Latest Advances in Understanding Preeclampsia

Redman, C. W., & Sargent, I. L. (2005) · Science · doi:10.1126/science.1111726 · Cited by 2,607 · see citing works

Preeclampsia: an endothelial cell disorder

Roberts, J. M., Taylor, R. N., Musci, T. J., Rodgers, G. M., Hubel, C. A., & McLaughlin, M. K. (1989) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(89)90665-0 · Cited by 1,859 · see citing works

VEGF-Trap: A VEGF blocker with potent antitumor effects

Holash, J., Davis, S., Papadopoulos, N., Croll, S. D., Ho, L., Russell, M., Boland, P., Leidich, R., Hylton, D., Burova, E., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.172398299 · Cited by 1,691 · see citing works

Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

McAllister, K. A., Grogg, K. M., Johnson, D. W., Gallione, C. J., Baldwin, M. A., Jackson, C. E., Helmbold, E. A., Markel, D. S., McKinnon, W. C., Murrel, J., et al. (1994) · Nature Genetics · doi:10.1038/ng1294-345 · Cited by 1,475 · see citing works

Syndrome of hemolysis, elevated liver enzymes, and low platelet count: a severe consequence of hypertension in pregnancy

Weinstein, L. (1982) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(16)32330-4 · Cited by 1,252 · see citing works

Nitric oxide production contributes to the angiogenic properties of vascular endothelial growth factor in human endothelial cells.

Papapetropoulos, A., García‐Cardeña, G., Madri, J. A., & Sessa, W. C. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119868 · Cited by 1,192 · see citing works

Pre-eclampsia

Sibai, B. M., Dekker, G. A., & Kupferminc, M. J. (2005) · The Lancet · doi:10.1016/s0140-6736(05)71003-5 · Cited by 1,089 · see citing works

Dynamic activation of endothelial nitric oxide synthase by Hsp90

García‐Cardeña, G., Fan, R., Shah, V. H., Sorrentino, R., Cirino, G., Papapetropoulos, A., & Sessa, W. C. (1998) · Nature · doi:10.1038/33934 · Cited by 1,029 · see citing works

Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?

Zhou, Y., Fisher, S. J., Janatpour, M. J., Genbačev, O., Dejana, E., Wheelock, M., & Damsky, C. H. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119387 · Cited by 957 · see citing works

Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome?

Zhou, Y., Damsky, C. H., & Fisher, S. J. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119388 · Cited by 937 · see citing works

Elevated blood pressures in mice lacking endothelial nitric oxide synthase

Shesely, E. G., Maeda, N., Kim, H.-S., Desai, K. M., Krege, J. H., Laubach, V. E., Sherman, P. A., Sessa, W. C., & Smithies, O. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.23.13176 · Cited by 914 · see citing works

Defective Angiogenesis in Mice Lacking Endoglin

Li, D. Y., Sorensen, L. K., Brooke, B. S., Urness, L. D., Davis, E. C., Taylor, D. G., Boak, B. B., & Wendel, D. P. (1999) · Science · doi:10.1126/science.284.5419.1534 · Cited by 853 · see citing works

Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells.

Cheifetz, S., Bellón, T., Calés, C., Vera, S., Bernabéu, C., Massagué, J., & Letarte, M. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)41732-2 · Cited by 836 · see citing works

Phosphorylation of Thr ⁴⁹⁵ Regulates Ca ²⁺ /Calmodulin-Dependent Endothelial Nitric Oxide Synthase Activity

Fleming, I., Fisslthaler, B., Dimmeler, S., Kemp, B. E., & Busse, R. (2001) · Circulation Research · doi:10.1161/hh1101.092677 · Cited by 770 · cited 1× · see citing works

Vascular Endothelial Growth Factor Ligands and Receptors That Regulate Human Cytotrophoblast Survival Are Dysregulated in Severe Preeclampsia and Hemolysis, Elevated Liver Enzymes, and Low Platelets Syndrome

Zhou, Y., McMaster, M., Woo, K., Janatpour, M. J., Perry, J., Kärpänen, T., Alitalo, K. K., Damsky, C. H., & Fisher, S. J. (2002) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)62567-9 · Cited by 639 · see citing works

Endoglin Is an Accessory Protein That Interacts with the Signaling Receptor Complex of Multiple Members of the Transforming Growth Factor-β Superfamily

Pece-Barbara, N., Wrana, J. L., & Letarte, M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.2.584 · Cited by 564 · see citing works

Elevated Placental Soluble Vascular Endothelial Growth Factor Receptor-1 Inhibits Angiogenesis in Preeclampsia

Ahmad, S., & Ahmed, A. (2004) · Circulation Research · doi:10.1161/01.res.0000147365.86159.f5 · Cited by 516 · see citing works

Vascular Endothelial Growth Factor Signals Endothelial Cell Production of Nitric Oxide and Prostacyclin through Flk-1/KDR Activation of c-Src

He, H., Venema, V. J., Gu, X., Venema, R. C., Marrero, M. B., & Caldwell, R. B. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.35.25130 · Cited by 488 · see citing works

A murine model of hereditary hemorrhagic telangiectasia

Bourdeau, A., Dumont, D., & Letarte, M. (1999) · Journal of Clinical Investigation · doi:10.1172/jci8088 · Cited by 471 · see citing works

Longitudinal serum concentrations of placental growth factor: Evidence for abnormal placental angiogenesis in pathologic pregnancies

Taylor, R. N., Grimwood, J., Taylor, R. S., McMaster, M., Fisher, S. J., & North, R. A. (2003) · American Journal of Obstetrics and Gynecology · doi:10.1067/mob.2003.111 · Cited by 410 · see citing works

Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival

Darland, D. C., Massingham, L. J., Smith, S. R., Piek, E., Saint‐Geniez, M., & D'Amore, P. A. (2003) · Developmental Biology · doi:10.1016/j.ydbio.2003.08.015 · Cited by 383 · see citing works

c-Ski Acts as a Transcriptional Co-repressor in Transforming Growth Factor-β Signaling through Interaction with Smads

Akiyoshi, S., Inoue, H., Hanai, J., Kusanagi, K., Nemoto, N., Miyazono, K., & Kawabata, M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.49.35269 · Cited by 373 · see citing works

Evidence supporting a role for blockade of the vascular endothelial growth factor system in the pathophysiology of preeclampsia

Chaiworapongsa, T., Romero, R., Espinoza, J., Bujold, E., Mee Kim, Y., Gonçalves, L. F., Gomez, R., & Edwin, S. (2004) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2004.03.043 · Cited by 368 · see citing works

Phosphorylation of the endothelial nitric oxide synthase at Ser‐1177 is required for VEGF‐induced endothelial cell migration

Dimmeler, S., Dernbach, E., & Zeiher, A. M. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01657-4 · Cited by 366 · see citing works

Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia

Chaiworapongsa, T., Romero, R., Kim, Y. M., Kim, G. J., Kim, M. R., Espinoza, J., Bujold, E., Gonçalves, L., Gomez, R., Edwin, S., et al. (2005) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767050400028816 · Cited by 359 · see citing works

Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer

Kuo, C. J., Farnebo, F. A., Yu, E. Y., Christofferson, R. H. B., Swearingen, R. A., Carter, R., von Recum, H. A., Yuan, J., Kamihara, J., Flynn, E. A., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.081615298 · Cited by 268 · see citing works

A Role for Endoglin in Coupling eNOS Activity and Regulating Vascular Tone Revealed in Hereditary Hemorrhagic Telangiectasia

Toporsian, M., Gros, R., Kabir, M. G., Vera, S., Govindaraju, K., Eidelman, D. H., Husain, M., & Letarte, M. (2005) · Circulation Research · doi:10.1161/01.res.0000159936.38601.22 · Cited by 249 · see citing works

Endoglin Regulates Trophoblast Differentiation along the Invasive Pathway in Human Placental Villous Explants

Caniggia, I., Taylor, C. V. L., Ritchie, J. W. K., Lye, S. J., & Letarte, M. (1997) · Endocrinology · doi:10.1210/endo.138.11.5475 · Cited by 200 · see citing works

Molecular Regulation of the Bovine Endothelial Cell Nitric Oxide Synthase by Transforming Growth Factor–β 1

Inoue, N., Venema, R. C., Sayegh, H. S., Ohara, Y., Murphy, T. J., & Harrison, D. G. (1995) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.15.8.1255 · Cited by 192 · see citing works

Maternal Serum sFlt1 Concentration Is an Early and Reliable Predictive Marker of Preeclampsia

Hertig, A., Berkane, N. B., Lefèvre, G., Toumi, K., Marti, H., Capeau, J., Uzan, S., & Rondeau, É. (2004) · Clinical Chemistry · doi:10.1373/clinchem.2004.036715 · Cited by 186 · see citing works

Identification of distinct epitopes of endoglin, an RGD-containing glycoprotein of endothelial cells, leukemic cells, and syncytiotrophoblasts

Gougos, A., St‐Jacques, S., Greaves, A., O'Connell, P., d’Apice, A. J. F., Bühring, H.-J., Bernabéu, C., van MOURIK, J. A., & Letarte, M. (1992) · International Immunology · doi:10.1093/intimm/4.1.83 · Cited by 185 · see citing works

Prostacyclin and Thromboxane Changes Predating Clinical Onset of Preeclampsia

Mills, J. L., DerSimonian, R., Raymond, E. G., Morrow, J. D., Roberts, L. J., Clemens, J. D., Hauth, J. C., Catalano, P. M., Sibai, B. M., Curet, L. B., et al. (1999) · JAMA · doi:10.1001/jama.282.4.356 · Cited by 178 · see citing works

Nitric Oxide Dysfunction in the Pathophysiology of Preeclampsia

Lowe, D. T. (2000) · Nitric Oxide · doi:10.1006/niox.2000.0296 · Cited by 174 · see citing works

The Shedding of Betaglycan Is Regulated by Pervanadate and Mediated by Membrane Type Matrix Metalloprotease-1

Velasco-Loyden, G., Arribas, J., & López‐Casillas, F. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m306499200 · Cited by 144 · see citing works

Constitutive eNOS-derived nitric oxide is a determinant of endothelial junctional integrity

Predescu, D. N., Predescu, S. A., Shimizu, J., Miyawaki-Shimizu, K., & Malik, A. B. (2005) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00175.2004 · Cited by 143 · see citing works

Localization of Endoglin, a Transforming Growth Factor-β Binding Protein, and of CD44 and Integrins in Placenta during the First Trimester of Pregnancy1

St‐Jacques, S., Forte, M., Lye, S. J., & Letarte, M. (1994) · Biology of Reproduction · doi:10.1095/biolreprod51.3.405 · Cited by 128 · see citing works

Capillary Permeability and Extracellular Fluid Volumes in Pregnancy-Induced Hypertension

Brown, M. A., Zammit, V. C., & Lowe, S. A. (1989) · Clinical Science · doi:10.1042/cs0770599 · Cited by 121 · see citing works

Angiogenic imbalance in the pathophysiology of preeclampsia: Newer insights

Bdolah, Y., Sukhatme, V. P., & Karumanchi, S. A. (2004) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2004.07.003 · Cited by 113 · see citing works

DNA-adduct levels as a predictor of outcome for NSCLC patients receiving daily cisplatin and radiotherapy

van de Vaart, P. J. M., Belderbos, J. S. A., de Jong, D., Sneeuw, K. C. A., Majoor, D. M., Bartelink, H. G. M. M., & Begg, A. C. (2000) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(20000320)89:2 · Cited by 102 · see citing works

Angiogenic imbalance in the pathophysiology of preeclampsia: Newer insights

Bdolah, Y., Sukhatme, V. P., & Karumanchi, S. A. (2004) · Seminars in Nephrology · doi:10.1016/s0270-9295(04)00125-1 · Cited by 90 · see citing works

Clinical Significance, Prevalence, and Natural History of Thrombocytopenia in Pregnancy-Induced Hypertension

Romero, R. J., Mazor, M., Lockwood, C. J., Emamian, M., Belanger, K., Hobbins, J. C., & Duffy, T. P. (1989) · American Journal of Perinatology · doi:10.1055/s-2007-999540 · Cited by 88 · see citing works

Plasma and Placental Levels of Interleukin-10, Transforming Growth Factor-β1, and Epithelial-Cadherin in Preeclampsia

Benian, A., Madazl, R., Aksu, F., Uzun, H., & Aydn, S. (2002) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(02)02077-x · Cited by 78 · see citing works

Smad2 Mediates Transforming Growth Factor-β Induction of Endothelial Nitric Oxide Synthase Expression

Saura, M., Zaragoza, C., Cao, W., Bao, C., Rodrı́guez-Puyol, M., Rodrı́guez-Puyol, D., & Lowenstein, C. J. (2002) · Circulation Research · doi:10.1161/01.res.0000040397.23817.e5 · Cited by 72 · see citing works

Endoglin (CD105): A Target for Anti-angiogenetic Cancer Therapy

Fonsatti, E., Altomonte, M., Arslan, P., & Maio, M. (2003) · Current Drug Targets · doi:10.2174/1389450033491073 · Cited by 58 · see citing works

Transforming growth factor-β1 (TGF-β1) in plasma is associated with preeclampsia risk in Peruvian women with systemic inflammation

Muy-Rivera, M. (2004) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2003.12.010 · Cited by 43 · see citing works

Effect of growth factors on human vascular endothelial cell prostacyclin production.

Ristimaki, A. P., Ylikorkala, O., & Viinikka, L. U. (1990) · Arteriosclerosis An Official Journal of the American Heart Association Inc · doi:10.1161/01.atv.10.4.653 · Cited by 37 · see citing works

Transforming growth factor‐β1 does not relate to hypertension in pre‐eclampsia

Hennessy, A., Orange, S., Willis, N. S., Painter, D., Child, A., & HORVATH, J. S. (2002) · Clinical and Experimental Pharmacology and Physiology · doi:10.1046/j.1440-1681.2002.03763.x · Cited by 24 · see citing works

Transforming Growth Factor-β1 Restores Antiplatelet Function of Endothelial Cells Exposed to Anoxia-Reoxygenation Injury

Tatsumi, M., Kishi, Y., Miyata, T., & Numano, F. (2000) · Thrombosis Research · doi:10.1016/s0049-3848(00)00190-0 · Cited by 9 · see citing works

Untitled work

Rana (2019) · doi:10.1161/circresaha.118.313276 · Cited by 2,095 · see citing works

Soluble Endoglin and Other Circulating Antiangiogenic Factors in Preeclampsia

Levine, R. J., Lam, C., Qian, C., Yu, K. F., Maynard, S. E., Sachs, B. P., Sibai, B. M., Epstein, F. H., Romero, R. J., Thadhani, R., et al. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa055352 · Cited by 1,804 · see citing works

Pre-eclampsia

Mol, B. W., Roberts, C. T., Thangaratinam, S., Magee, L. A., de Groot, C. J. M., & Hofmeyr, G. J. (2015) · The Lancet · doi:10.1016/s0140-6736(15)00070-7 · Cited by 1,619 · see citing works

The “Great Obstetrical Syndromes” are associated with disorders of deep placentation

Brosens, I., Pijnenborg, R., Vercruysse, L., & Romero, R. (2011) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2010.08.009 · Cited by 1,568 · see citing works

Inflammatory cytokines in vascular dysfunction and vascular disease

Sprague, A. H., & Khalil, R. A. (2009) · Biochemical Pharmacology · doi:10.1016/j.bcp.2009.04.029 · Cited by 1,347 · see citing works

Pre-eclampsia: pathogenesis, novel diagnostics and therapies

Phipps, E. A., Thadhani, R., Benzing, T. R., & Karumanchi, S. A. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-019-0119-6 · Cited by 1,255 · see citing works

Stem cell-based therapy for human diseases

Hoang, D. M., Pham, P. T., Bach, T. Q., Ngo, A. T. L., Nguyen, Q. T., Phan, T. T. K., Nguyen, G. H., Le, P. T. T., Hoang, V. T., Forsyth, N. R., et al. (2022) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-022-01134-4 · Cited by 1,074 · see citing works

Pre-eclampsia

Dimitriadis, E., Rolnik, D. L., Zhou, W., Estrada‐Gutiérrez, G., Koga, K., Francisco, R. P. V., Whitehead, C. L., Hyett, J. A., Costa, F. D. S., Nicolaides, K. H., et al. (2023) · Nature Reviews Disease Primers · doi:10.1038/s41572-023-00417-6 · Cited by 1,006 · see citing works

Preeclampsia, a Disease of the Maternal Endothelium

Powe, C. E., Levine, R. J., & Karumanchi, S. A. (2011) · Circulation · doi:10.1161/circulationaha.109.853127 · Cited by 972 · see citing works

Pre-eclampsia part 1: current understanding of its pathophysiology

Chaiworapongsa, T., Chaemsaithong, P., Yeo, L., & Romero, R. (2014) · Nature Reviews Nephrology · doi:10.1038/nrneph.2014.102 · Cited by 956 · see citing works

TGF-β Signaling

Tzavlaki, K., & Moustakas, A. (2020) · Biomolecules · doi:10.3390/biom10030487 · Cited by 816 · see citing works

Extracellular control of TGFβ signalling in vascular development and disease

ten Dijke, P., & Arthur, H. M. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2262 · Cited by 777 · see citing works

Pathogenesis of Preeclampsia

Young, B. C., Levine, R. J., & Karumanchi, S. A. (2010) · Annual Review of Pathology Mechanisms of Disease · doi:10.1146/annurev-pathol-121808-102149 · Cited by 722 · see citing works

A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate

Romero, R. J., Nien, J. K., Espinoza, J., Todem, D., Fu, W., Chung, H., Kusanovic, J. P., Gotsch, F., Erez, O., Mazaki‐Tovi, S., et al. (2008) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767050701830480 · Cited by 675 · see citing works

Role of transforming growth factor-β superfamily signaling pathways in human disease

Gordon, K. J., & Blobe, G. C. (2008) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2008.01.006 · Cited by 644 · see citing works

Preeclampsia: Updates in Pathogenesis, Definitions, and Guidelines

Phipps, E., Prasanna, D., Brima, W., & Jim, B. (2016) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.12081115 · Cited by 633 · see citing works

Why is placentation abnormal in preeclampsia?

Fisher, S. J. (2015) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.08.042 · Cited by 632 · see citing works

Endogenous VEGF Is Required for Visual Function: Evidence for a Survival Role on Müller Cells and Photoreceptors

Saint‐Geniez, M., Maharaj, A. S. R., Walshe, T. E., Tucker, B. A., Sekiyama, E., Kurihara, T., Darland, D. C., Young, M. J., & D'Amore, P. A. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003554 · Cited by 615 · see citing works

TGF-β signaling in vascular biology and dysfunction

Goumans, M., Liu, Z., & ten Dijke, P. (2008) · Cell Research · doi:10.1038/cr.2008.326 · Cited by 606 · see citing works

Placental Stress and Pre-eclampsia: A Revised View

Redman, C. W. G., & Sargent, I. L. (2009) · Placenta · doi:10.1016/j.placenta.2008.11.021 · Cited by 601 · see citing works

Cardiac angiogenic imbalance leads to peripartum cardiomyopathy

Patten, I. S., Rana, S., Shahul, S. S., Rowe, G. C., Jang, C., Liu, L., Hacker, M. R., Rhee, J. S., Mitchell, J., Mahmood, F. U., et al. (2012) · Nature · doi:10.1038/nature11040 · Cited by 570 · see citing works

Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction

Gilbert, J. S., Ryan, M. J., LaMarca, B. B., Sedeek, M. H., Murphy, S., & Granger, J. P. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01113.2007 · Cited by 553 · see citing works

Preeclampsia: The Role of Angiogenic Factors in Its Pathogenesis

Wang, A., Rana, S., & Karumanchi, S. A. (2009) · Physiology · doi:10.1152/physiol.00043.2008 · Cited by 552 · see citing works

Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array

Szarka, A., Rigó, J., Lázár, L., Bekő, G., & Molvarec, A. (2010) · BMC Immunology · doi:10.1186/1471-2172-11-59 · Cited by 516 · see citing works

Endothelium structure and function in kidney health and disease

Jourde‐Chiche, N., Fakhouri, F., Dou, L., Bellien, J., Burtey, S., Frimat, M., Jarrot, P., Kaplanski, G., Quintrec, M. L., Pernin, V., et al. (2019) · Nature Reviews Nephrology · doi:10.1038/s41581-018-0098-z · Cited by 499 · see citing works

Angiogenic Factors and Preeclampsia

Maynard, S. E., & Karumanchi, S. A. (2011) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2010.10.004 · Cited by 482 · see citing works

Hereditary haemorrhagic telangiectasia: a clinical and scientific review

Govani, F. S., & Shovlin, C. L. (2009) · European Journal of Human Genetics · doi:10.1038/ejhg.2009.35 · Cited by 481 · see citing works

Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice

Zhou, C. C., Zhang, Y., Irani, R. A., Zhang, H., Mi, T., Popek, E. J., Hicks, J. M., Ramin, S. M., Kellems, R. E., & Xia, Y. (2008) · Nature Medicine · doi:10.1038/nm.1856 · Cited by 470 · see citing works

Systemic Increase in the Ratio between Foxp3+ and IL-17-Producing CD4+ T Cells in Healthy Pregnancy but Not in Preeclampsia

Santner‐Nanan, B., Peek, M. J., Khanam, R., Richarts, L., Zhu, E., Groth, B. F. D. S., & Nanan, R. K. H. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901154 · Cited by 465 · see citing works

Pathological aspects of lipid peroxidation

Nègre‐Salvayre, A., Augè, N., Ayala, V., Başağa, H., Boada, J., Brenke, R., Chapple, S. J., Cohen, G., Fehér, J., Grune, T., et al. (2010) · Free Radical Research · doi:10.3109/10715762.2010.498478 · Cited by 451 · see citing works

Placental Productions and Expressions of Soluble Endoglin, Soluble fms-Like Tyrosine Kinase Receptor-1, and Placental Growth Factor in Normal and Preeclamptic Pregnancies

Gu, Y., Lewis, D. F., & Wang, Y. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1550 · Cited by 434 · see citing works

Pre-eclampsia: its pathogenesis and pathophysiolgy

Gathiram, P., & Moodley, J. (2016) · Cardiovascular journal of South Africa/Cardiovascular journal of Southern Africa · doi:10.5830/cvja-2016-009 · Cited by 433 · see citing works

Bioactive factors in uteroplacental and systemic circulation link placental ischemia to generalized vascular dysfunction in hypertensive pregnancy and preeclampsia

Shah, D. A., & Khalil, R. A. (2015) · Biochemical Pharmacology · doi:10.1016/j.bcp.2015.04.012 · Cited by 421 · see citing works

Negative Regulation of Soluble Flt-1 and Soluble Endoglin Release by Heme Oxygenase-1

Cudmore, M., Ahmad, S., Al‐Ani, B., Fujisawa, T., Coxall, H., Chudasama, K., Devey, L. R., Wigmore, S. J., Abbas‐Hanif, A., Hewett, P. W., et al. (2007) · Circulation · doi:10.1161/circulationaha.106.660134 · Cited by 421 · see citing works

Syncytiotrophoblast stress in preeclampsia: the convergence point for multiple pathways

Redman, C. W. G., Staff, A. C., & Roberts, J. M. (2021) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.09.047 · Cited by 411 · see citing works

Signaling by members of the TGF-β family in vascular morphogenesis and disease

Pardali, E., Goumans, M., & ten Dijke, P. (2010) · Trends in Cell Biology · doi:10.1016/j.tcb.2010.06.006 · Cited by 402 · see citing works

Oxidative stress: Normal pregnancy versus preeclampsia

Chiarello, D. I., Abad, C., Rojas, D., Toledo, F., Vázquez, C. M., Mate, A., Sobrevía, L., & Marı́n, R. (2018) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2018.12.005 · Cited by 394 · see citing works

Placental trophoblast cell differentiation: Physiological regulation and pathological relevance to preeclampsia

Ji, L., Brkić, J., Liu, M., Fu, G., Peng, C., & Wang, Y. (2012) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2012.12.008 · Cited by 386 · see citing works

Redefining Preeclampsia Using Placenta-Derived Biomarkers

Staff, A. C., Benton, S. J., von Dadelszen, P., Roberts, J. M., Taylor, R. N., Powers, R. W., Jones, D. S., & Redman, C. W. G. (2013) · Hypertension · doi:10.1161/hypertensionaha.111.00250 · Cited by 375 · see citing works

Pravastatin induces placental growth factor (PGF) and ameliorates preeclampsia in a mouse model

Kumasawa, K., Ikawa, M., Kidoya, H., Hasuwa, H., Saito‐Fujita, T., Morioka, Y., Takakura, N., Kimura, T., & Okabe, M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1011293108 · Cited by 366 · see citing works

Preeclampsia and Diabetes

Weissgerber, T. L., & Mudd, L. M. (2015) · Current Diabetes Reports · doi:10.1007/s11892-015-0579-4 · Cited by 364 · see citing works

Prospective Study of Placental Angiogenic Factors and Maternal Vascular Function Before and After Preeclampsia and Gestational Hypertension

Noori, M., Donald, A. E., Angelakopoulou, A., Hingorani, A. D., & Williams, D. J. (2010) · Circulation · doi:10.1161/circulationaha.109.895458 · Cited by 361 · see citing works

The role of the immune system in preeclampsia

Saito, S., Shiozaki, A., Nakashima, A., Sakai, M., & Sasaki, Y. (2007) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2007.02.006 · Cited by 352 · see citing works

Imbalances in circulating angiogenic factors in the pathophysiology of preeclampsia and related disorders

Rana, S., Burke, S. D., & Karumanchi, S. A. (2020) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2020.10.022 · Cited by 351 · see citing works

Manufacturing of primed mesenchymal stromal cells for therapy

Yin, J. Q., Zhu, J., & Ankrum, J. A. (2019) · Nature Biomedical Engineering · doi:10.1038/s41551-018-0325-8 · Cited by 345 · see citing works

Activated vitamin D attenuates left ventricular abnormalities induced by dietary sodium in Dahl salt-sensitive animals

Bodyak, N. D., Ayus, J. C., Achinger, S. G., Venkatesha, S., Ke, Q., Chen, Y.-S., Rigor, D. L., Stillman, I. E., Tamez, H. E., Kroeger, P. E., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611202104 · Cited by 332 · see citing works

Preeclampsia and Angiogenic Imbalance

Maynard, S. E., Epstein, F. H., & Karumanchi, S. A. (2007) · Annual Review of Medicine · doi:10.1146/annurev.med.59.110106.214058 · Cited by 331 · see citing works

Uteroplacental ischemia results in proteinuric hypertension and elevated sFLT-1

Makris, A., Thornton, C. E., Thompson, J., Thomson, S. E., Martin, R., Ogle, R. F., Waugh, R., McKenzie, P. R., Kirwan, P., & Hennessy, A. (2007) · Kidney International · doi:10.1038/sj.ki.5002175 · Cited by 330 · see citing works

Critical growth factors and signalling pathways controlling human trophoblast invasion

Knfler, M. (2009) · The International Journal of Developmental Biology · doi:10.1387/ijdb.082769mk · Cited by 330 · see citing works

Endoglin in angiogenesis and vascular diseases

ten Dijke, P., Goumans, M., & Pardali, E. (2008) · Angiogenesis · doi:10.1007/s10456-008-9101-9 · Cited by 329 · see citing works

The Glomerular Injury of Preeclampsia

Stillman, I. E., & Karumanchi, S. A. (2007) · Journal of the American Society of Nephrology · doi:10.1681/asn.2007020255 · Cited by 329 · see citing works

Pathogenesis of the syndrome of hemolysis, elevated liver enzymes, and low platelet count (HELLP): a review

Abildgaard, U., & Heimdal, K. (2013) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2012.09.026 · Cited by 325 · see citing works

Defective decidualization during and after severe preeclampsia reveals a possible maternal contribution to the etiology

Garrido‐Gómez, T., Domı́nguez, F., Quiñonero, A., Díaz-Gimeno, P., Kapidzic, M., Gormley, M. J., Ona, K., Padilla-Iserte, P., McMaster, M., Genbačev, O., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1706546114 · Cited by 322 · see citing works

Molecular mechanisms of preeclampsia

Mutter, W. P., & Karumanchi, S. A. (2007) · Microvascular Research · doi:10.1016/j.mvr.2007.04.009 · Cited by 314 · see citing works

Preeclampsia and eclampsia: the conceptual evolution of a syndrome

Erez, O., Romero, R. J., Jung, E., Chaemsaithong, P., Bosco, M., Suksai, M., Gallo, D. M., & Gotsch, F. (2022) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2021.12.001 · Cited by 311 · see citing works

Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia

Guerby, P., Tasta, O., Swiader, A., Pont, F., Bujold, E., Parant, O., Vayssière, C., Salvayre, R., & Nègre‐Salvayre, A. (2021) · Redox Biology · doi:10.1016/j.redox.2021.101861 · Cited by 309 · see citing works

Heme Oxygenase-1 and Carbon Monoxide in Vascular Pathobiology

Dulak, J., Deshane, J. S., Józkowicz, A., & Agarwal, A. (2008) · Circulation · doi:10.1161/circulationaha.107.698316 · Cited by 303 · see citing works

Role of corin in trophoblast invasion and uterine spiral artery remodelling in pregnancy

Cui, Y., Wang, W., Dong, N., Lou, J., Srinivasan, D. K., Cheng, W., Huang, X., Liu, M., Fang, C., Peng, J., et al. (2012) · Nature · doi:10.1038/nature10897 · Cited by 301 · see citing works

Analysis of microarray experiments of gene expression profiling

Tarca, A. L., Romero, R. J., & Drăghici, S. (2006) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2006.07.001 · Cited by 301 · see citing works

<scp>SOMANZ</scp>guidelines for the management of hypertensive disorders of pregnancy 2014

Lowe, S. A., Bowyer, L., Lust, K., McMahon, L. P., Morton, M., North, R. A., Paech, M., & Said, J. M. (2015) · Australian and New Zealand Journal of Obstetrics and Gynaecology · doi:10.1111/ajo.12399 · Cited by 299 · see citing works

Placental lesions associated with maternal underperfusion are more frequent in early-onset than in late-onset preeclampsia

Oggè, G., Chaiworapongsa, T., Romero, R. J., Hussein, Y., Kusanovic, J. P., Yeo, L., Kim, C. J., & Hassan, S. S. (2011) · Journal of Perinatal Medicine · doi:10.1515/jpm.2011.098 · Cited by 298 · see citing works

The placenta: transcriptional, epigenetic, and physiological integration during development

Maltepe, E., Bakardjiev, A. I., & Fisher, S. J. (2010) · Journal of Clinical Investigation · doi:10.1172/jci41211 · Cited by 298 · see citing works

Potential markers of preeclampsia – a review

Grill, S., Rusterholz, C., Zanetti‐Dällenbach, R., Tercanli, S., Holzgreve, W., Hahn, S., & Lapaire, O. (2009) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-7-70 · Cited by 294 · see citing works

Vascular biology of preeclampsia

Myatt, L., & Webster, R. P. (2009) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2008.03259.x · Cited by 292 · see citing works

Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development

Ilekis, J. V., Tsilou, E. T., Fisher, S. J., Abrahams, V. M., Soares, M. J., Cross, J. C., Zamudio, S., Illsley, N. P., Myatt, L., Colvis, C. M., et al. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2016.03.001 · Cited by 291 · see citing works

Short-term costs of preeclampsia to the United States health care system

Stevens, W., Shih, T. M., Incerti, D., Ton, T. G. N., Lee, H. C., Peneva, D., Macones, G. A., Sibai, B. M., & Jena, A. B. (2017) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2017.04.032 · Cited by 290 · see citing works

The placenta in pre-eclampsia and intrauterine growth restriction

Roberts, D. J., & Post, M. D. (2008) · Journal of Clinical Pathology · doi:10.1136/jcp.2008.055236 · Cited by 288 · see citing works

The change in concentrations of angiogenic and anti-angiogenic factors in maternal plasma between the first and second trimesters in risk assessment for the subsequent development of preeclampsia and small-for-gestational age

Erez, O., Romero, R., Espinoza, J., Fu, W., Todem, D., Kusanovic, J. P., Gotsch, F., Edwin, S., Nien, J. K., Chaiworapongsa, T., et al. (2008) · The Journal of Maternal-Fetal &amp; Neonatal Medicine · doi:10.1080/14767050802034545 · Cited by 287 · see citing works

Preeclampsia: multiple approaches for a multifactorial disease

Pennington, K. A., Schlitt, J. M., Jackson, D. L., Schulz, L. C., & Schust, D. J. (2012) · Disease Models & Mechanisms · doi:10.1242/dmm.008516 · Cited by 286 · see citing works

Sequential Changes in Antiangiogenic Factors in Early Pregnancy and Risk of Developing Preeclampsia

Rana, S., Karumanchi, S. A., Levine, R. J., Venkatesha, S., Rauh‐Hain, J. A., Tamez, H. E., & Thadhani, R. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.087700 · Cited by 286 · see citing works

Preeclampsia: Maternal Systemic Vascular Disorder Caused by Generalized Endothelial Dysfunction Due to Placental Antiangiogenic Factors

Tomimatsu, T., Mimura, K., Matsuzaki, S., Endo, M., Kumasawa, K., & Kimura, T. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20174246 · Cited by 282 · see citing works

Emerging role of bone morphogenetic proteins in angiogenesis

David, L., Feige, J., & Bailly, S. (2009) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2009.05.001 · Cited by 281 · see citing works

Matrix Metalloproteinases in Normal Pregnancy and Preeclampsia

Chen, J., & Khalil, R. A. (2017) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2017.04.001 · Cited by 280 · see citing works

A prospective cohort study of the value of maternal plasma concentrations of angiogenic and anti-angiogenic factors in early pregnancy and midtrimester in the identification of patients destined to develop preeclampsia

Kusanovic, J. P., Romero, R. J., Chaiworapongsa, T., Erez, O., Mittal, P., Vaisbuch, E., Mazaki‐Tovi, S., Gotsch, F., Edwin, S. S., Gómez, R., et al. (2009) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767050902994754 · Cited by 277 · see citing works

Matrix Metalloproteinase-14 (MT1-MMP)–Mediated Endoglin Shedding Inhibits Tumor Angiogenesis

Hawinkels, L. J. A. C., Kuiper, P., Wiercinska, E., Verspaget, H. W., Liu, Z., Pardali, E., Sier, C. F. M., & ten Dijke, P. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-4466 · Cited by 270 · see citing works

Pathophysiology of the Clinical Manifestations of Preeclampsia

Hladunewich, M., Karumanchi, S. A., & Lafayette, R. A. (2007) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.03761106 · Cited by 268 · see citing works

Vascular Dysfunction in Preeclampsia

Opichka, M. A., Rappelt, M. W., Gutterman, D. D., Grobe, J. L., & McIntosh, J. J. (2021) · Cells · doi:10.3390/cells10113055 · Cited by 268 · see citing works

Recombinant Vascular Endothelial Growth Factor 121 Attenuates Hypertension and Improves Kidney Damage in a Rat Model of Preeclampsia

Li, Z., Zhang, Y., Jing, Y., Kapoun, A. M., Shao, Q., Kerr, I., Lam, A., O’Young, G., Sannajust, F. J., Stathis, P., et al. (2007) · Hypertension · doi:10.1161/hypertensionaha.107.092098 · Cited by 258 · see citing works

Pathogenesis of preeclampsia

Sircar, M., Thadhani, R., & Karumanchi, S. A. (2015) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0000000000000105 · Cited by 256 · see citing works

The glomerular filtration barrier: a structural target for novel kidney therapies

Daehn, I. S., & Duffield, J. S. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-021-00242-0 · Cited by 255 · see citing works

The emerging role of TGF-β superfamily coreceptors in cancer

Bernabéu, C., López-Novoa, J. M., & Quintanilla, M. (2009) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2009.07.003 · Cited by 254 · see citing works

Metformin, the Aspirin of the 21st Century: Its Role in Gestational Diabetes Mellitus, Prevention of Preeclampsia and Cancer, and the Promotion of Longevity

Romero, R., Erez, O., Hüttemann, M., Maymon, E., Panaitescu, B., Conde-Agudelo, A., Pacora, P., Yoon, B. H., & Grossman, L. I. (2017) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2017.06.003 · Cited by 253 · see citing works

Preeclampsia: Pathogenesis, Prevention, and Long-Term Complications

Jim, B., & Karumanchi, S. A. (2017) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2017.05.011 · Cited by 250 · see citing works

Mechanisms of Endothelial Dysfunction in Hypertensive Pregnancy and Preeclampsia

Possomato‐Vieira, J. S., & Khalil, R. A. (2016) · Advances in pharmacology · doi:10.1016/bs.apha.2016.04.008 · Cited by 244 · see citing works

Dysregulation of the Circulating and Tissue-Based Renin-Angiotensin System in Preeclampsia

Herse, F., Dechend, R., Harsem, N. K., Wallukat, G., Janke, J., Qadri, F., Hering, L., Müller, D. N., Luft, F. C., & Staff, A. C. (2007) · Hypertension · doi:10.1161/01.hyp.0000257797.49289.71 · Cited by 243 · see citing works

A Brief Overview of Preeclampsia

Al-Jameil (2013) · Journal of Clinical Medicine Research · doi:10.4021/jocmr1682w · Cited by 241 · see citing works

Twin pregnancy and the risk of preeclampsia: bigger placenta or relative ischemia?

Bdolah, Y., Lam, C., Rajakumar, A., Venkatesha, S., Mutter, W. P., Sachs, B. P., Lim, K. H., Bdolah‐Abram, T., Epstein, F. H., & Karumanchi, S. A. (2008) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2007.10.783 · Cited by 240 · see citing works

Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors

Cheng, S., Nakashima, A., Huber, W. J., Davis, S., Banerjee, S., Huang, Z., Saito, S., Sadovsky, Y., & Sharma, S. (2019) · Cell Death and Disease · doi:10.1038/s41419-019-2162-4 · Cited by 238 · see citing works

The role of hypoxia and hypoxia-inducible factor-1alpha in preeclampsia pathogenesis

Tal, R. (2012) · Biology of Reproduction · doi:10.1095/biolreprod.112.102723 · Cited by 235 · see citing works

Learning From the Placenta

Staff, A. C., Dechend, R., & Pijnenborg, R. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.157743 · Cited by 231 · see citing works

Maternal Preeclampsia Predicts the Development of Bronchopulmonary Dysplasia

Hansen, A. R., Barnés, C. M., Folkman, J., & McElrath, T. F. (2009) · The Journal of Pediatrics · doi:10.1016/j.jpeds.2009.10.018 · Cited by 229 · see citing works

Vascular Dysfunction in Women With a History of Preeclampsia and Intrauterine Growth Restriction

Yinon, Y., Kingdom, J. C., Odutayo, A., Moineddin, R., Drewlo, S., LAI, V. S., Cherney, D. Z. I., & Hladunewich, M. (2010) · Circulation · doi:10.1161/circulationaha.110.948455 · Cited by 229 · see citing works

A model of preeclampsia in rats: the reduced uterine perfusion pressure (RUPP) model

Li, J., LaMarca, B. B., & Reckelhoff, J. F. (2012) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00117.2012 · Cited by 226 · see citing works

Vascular mechanisms and molecular targets in hypertensive pregnancy and preeclampsia

Qu, H., & Khalil, R. A. (2020) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00202.2020 · Cited by 226 · see citing works

Targeting BMP signalling in cardiovascular disease and anaemia

Morrell, N. W., Bloch, D. B., ten Dijke, P., Goumans, M., Hata, A., Smith, J., Yu, P. B., & Bloch, K. D. (2015) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2015.156 · Cited by 223 · see citing works

Metformin as a prevention and treatment for preeclampsia: effects on soluble fms-like tyrosine kinase 1 and soluble endoglin secretion and endothelial dysfunction

Brownfoot, F. C., Hastie, R., Hannan, N. J., Cannon, P., Tuohey, L., Parry, L. J., Senadheera, S., Illanes, S. E., Kaitu’u-Lino, T. J., & Tong, S. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.12.019 · Cited by 222 · see citing works

Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth

Castonguay, R., Werner, E. D., Matthews, R. G., Presman, E., Mulivor, A. W., Solban, N., Sako, D., Pearsall, R. S., Underwood, K. W., Seehra, J. S., et al. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m111.260133 · Cited by 221 · see citing works

ELABELA deficiency promotes preeclampsia and cardiovascular malformations in mice

Ho, L., van Dijk, M., Chye, S. T. J., Messerschmidt, D. M., Chng, S. C., Ong, S. L. M., Yi, L. K., Boussata, S., Goh, G. H.-Y., Afink, G., et al. (2017) · Science · doi:10.1126/science.aam6607 · Cited by 221 · see citing works

The physiological role of endoglin in the cardiovascular system

López-Novoa, J. M., & Bernabéu, C. (2010) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01251.2009 · Cited by 220 · see citing works

Impaired autophagy by soluble endoglin, under physiological hypoxia in early pregnant period, is involved in poor placentation in preeclampsia

Nakashima, A., Tatematsu, M., Fujita, N., Koizumi, K., Shima, T., Yoshida, T., Nikaido, T., Okamoto, A., Yoshimori, T., & Saito, S. (2013) · Autophagy · doi:10.4161/auto.22927 · Cited by 217 · see citing works

The role of endoglin and its soluble form in pathogenesis of preeclampsia

Margioula‐Siarkou, G., Margioula‐Siarkou, C., Petousis, S., Margaritis, K., Vavoulidis, Ε., Gullo, G., Alexandratou, M., Dinas, K. D., Sotiriadis, A., & Mavromatidis, G. (2021) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-021-04294-z · Cited by 82 · see citing works

Soluble Endoglin and Preeclampsia

He, Y., & Dong, M.-Y. (2009) · Journal of International Obstetrics and Gynecology

Soluble fms-like tyrosine kinase 1 and soluble endoglin are elevated circulating anti-angiogenic factors in pre-eclampsia

Liu, Z., Afink, G., & ten Dijke, P. (2012) · Pregnancy Hypertension · doi:10.1016/j.preghy.2012.06.003 · Cited by 27 · see citing works

Structural and Functional Characteristics of a Soluble Form of Endoglin in the Context of Preeclampsia

Gregory, A. (2011) · TSpace (University of Toronto) · Cited by 2 · see citing works

Membrane and Soluble Forms of Endoglin in Preeclampsia

Oujo, B., Pérez‐Barriocanal, F., Bernabéu, C., & López-Novoa, J. M. (2013) · Current Molecular Medicine · doi:10.2174/15665240113139990058 · Cited by 37 · see citing works