Latest Advances in Understanding Preeclampsia

MHC class I molecules and kirs in human history, health and survival

Parham, P. (2005) · Nature Reviews Immunology · doi:10.1038/nri1570 · Cited by 1,203 · see citing works

Placental oxidative stress: from miscarriage to preeclampsia

Burton, G. J., & Jauniaux, E. (2004) · Journal of the Society for Gynecologic Investigation · doi:10.1016/j.jsgi.2004.03.003 · Cited by 673 · see citing works

Gestational Hypertension and Preeclampsia

(2020) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000003891 · Cited by 2,949 · see citing works

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Rana (2019) · doi:10.1161/circresaha.118.313276 · Cited by 2,095 · see citing works

Soluble endoglin contributes to the pathogenesis of preeclampsia

Venkatesha, S., Toporsian, M., Lam, C., Hanai, J.-I., Mammoto, T., Kim, Y. M., Bdolah, Y., Lim, K.-H., Yuan, H.-T., Libermann, T. A., et al. (2006) · Nature Medicine · doi:10.1038/nm1429 · Cited by 1,855 · see citing works

Practice Bulletin No. 183: postpartum hemorrhage

(2017) · Obstetrics & Gynecology · doi:10.1097/aog.0000000000002351 · Cited by 1,406 · see citing works

Endothelial cells and VEGF in vascular development

Coultas, L., Chawengsaksophak, K., & Rossant, J. (2005) · Nature · doi:10.1038/nature04479 · Cited by 1,016 · see citing works

Pre-eclampsia part 1: current understanding of its pathophysiology

Chaiworapongsa, T., Chaemsaithong, P., Yeo, L., & Romero, R. (2014) · Nature Reviews Nephrology · doi:10.1038/nrneph.2014.102 · Cited by 956 · see citing works

Beneficial suicide: why neutrophils die to make NETs

Brinkmann, V., & Zychlinsky, A. (2007) · Nature Reviews Microbiology · doi:10.1038/nrmicro1710 · Cited by 937 · see citing works

Malaria in pregnancy: pathogenesis and immunity

Rogerson, S. J., Hviid, L., Duffy, P. E., Leke, R. F., & Taylor, D. W. (2007) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(07)70022-1 · Cited by 628 · see citing works

Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence

Thangaratinam, S., Tan, A., Knox, E., Kilby, M. D., Franklyn, J., & Coomarasamy, A. (2011) · BMJ · doi:10.1136/bmj.d2616 · Cited by 604 · see citing works

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

Kell, D. B. (2009) · BMC Medical Genomics · doi:10.1186/1755-8794-2-2 · Cited by 554 · see citing works

Placental endoplasmic reticulum stress and oxidative stress in the pathophysiology of unexplained intrauterine growth restriction and early onset preeclampsia

Burton, G. J., Yung, H.-W., Cindrova-Davies, T., & Charnock-Jones, D. S. (2009) · Placenta · doi:10.1016/j.placenta.2008.11.003 · Cited by 502 · see citing works

Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia

Kanasaki, K., Palmsten, K., Sugimoto, H., Ahmad, S., Hamano, Y., Xie, L., Parry, S., Augustin, H. G., Gattone, V. H., Folkman, J., et al. (2008) · Nature · doi:10.1038/nature06951 · Cited by 381 · see citing works

Preeclampsia, Placental Insufficiency, and Autism Spectrum Disorder or Developmental Delay

Walker, C. K., Krakowiak, P., Baker, A., Hansen, R. L., Ozonoff, S., & Hertz-Picciotto, I. (2015) · JAMA Pediatrics · doi:10.1001/jamapediatrics.2014.2645 · Cited by 292 · see citing works

Oxidative stress, placental ageing-related pathologies and adverse pregnancy outcomes

Sultana, Z., Maiti, K., Aitken, J., Morris, J., Dedman, L., & Smith, R. (2017) · American Journal of Reproductive Immunology · doi:10.1111/aji.12653 · Cited by 288 · see citing works

Metformin as a prevention and treatment for preeclampsia: effects on soluble fms-like tyrosine kinase 1 and soluble endoglin secretion and endothelial dysfunction

Brownfoot, F. C., Hastie, R., Hannan, N. J., Cannon, P., Tuohey, L., Parry, L. J., Senadheera, S., Illanes, S. E., Kaitu’u-Lino, T. J., & Tong, S. (2016) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2015.12.019 · Cited by 222 · see citing works

If we know so much about preeclampsia, why haven’t we cured the disease?

Roberts, J. M., & Bell, M. J. (2013) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2013.05.003 · Cited by 189 · see citing works

Maternal and umbilical serum levels of interleukin-6, interleukin-8, and tumor necrosis factor-α in normal pregnancies and in pregnancies complicated by preeclampsia

Tosun, M., Celik, H., Avci, B., Yavuz, E., Alper, T., & Malatyalioğlu, E. (2010) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767051003774942 · Cited by 185 · see citing works

A role for menstruation in preconditioning the uterus for successful pregnancy

Brosens, J. J., Parker, M. G., McIndoe, A., Pijnenborg, R., & Brosens, I. A. (2009) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2008.11.037 · Cited by 166 · see citing works

Angiogenic Factors in Preeclampsia: From Diagnosis to Therapy

Karumanchi, S. A. (2016) · Hypertension · doi:10.1161/hypertensionaha.116.06421 · Cited by 163 · see citing works

Etiology, clinical manifestations, and prediction of placental abruption

TIKKANEN, M. (2010) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016341003686081 · Cited by 158 · see citing works

Reduced Cystathionine γ-Lyase and Increased miR-21 Expression Are Associated with Increased Vascular Resistance in Growth-Restricted Pregnancies

Cindrova-Davies, T., Herrera, E. A., Niu, Y., Kingdom, J., Giussani, D. A., & Burton, G. J. (2013) · The American Journal of Pathology · doi:10.1016/j.ajpath.2013.01.001 · Cited by 135 · see citing works

Association between placental lesions, cytokines and angiogenic factors in pregnant women with preeclampsia

Weel, I. C., Baergen, R. N., Romão-Veiga, M., Borges, V. T., Ribeiro, V. R., Witkin, S. S., Bannwart-Castro, C., Peraçoli, J. C., De Oliveira, L., & Peraçoli, M. T. (2016) · PLoS ONE · doi:10.1371/journal.pone.0157584 · Cited by 131 · see citing works

Oxygen delivery and fetal-placental growth: Beyond a question of supply and demand?

Murray, A. J. (2012) · Placenta · doi:10.1016/j.placenta.2012.06.006 · Cited by 129 · see citing works

Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition

Colleoni, F., Padmanabhan, N., Yung, H.-W., Watson, E. D., Cetin, I., Tissot van Patot, M. C., Burton, G. J., & Murray, A. J. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055194 · Cited by 128 · see citing works

Clinical pharmacology and therapeutic use of antioxidant vitamins

Rodrigo, R., Guichard, C., & Charles, R. (2007) · Fundamental & Clinical Pharmacology · doi:10.1111/j.1472-8206.2006.00466.x · Cited by 124 · see citing works

Comparative proteomics analysis suggests that placental mitochondria are involved in the development of pre-eclampsia

Shi, Z., Long, W., Zhao, C., Guo, X., Shen, R., & Ding, H. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064351 · Cited by 118 · see citing works

Congenital Heart Defects and Indices of Placental and Fetal Growth in a Nationwide Study of 924 422 Liveborn Infants

Matthiesen, N. B., Henriksen, T. B., Agergaard, P., Gaynor, J. W., Bach, C. C., Hjortdal, V. E., & Østergaard, J. R. (2016) · Circulation · doi:10.1161/circulationaha.116.021793 · Cited by 112 · see citing works

Abnormalities in Oxygen Sensing Define Early and Late Onset Preeclampsia as Distinct Pathologies

Rolfo, A., Many, A., Racano, A., Tal, R., Tagliaferro, A., Ietta, F., Wang, J., Post, M., & Caniggia, I. (2010) · PLoS ONE · doi:10.1371/journal.pone.0013288 · Cited by 112 · see citing works

Associations between ambient air pollution and Hypertensive Disorders of Pregnancy

Mobasher, Z., Salam, M. T., Goodwin, T. M., Lurmann, F., Ingles, S. A., & Wilson, M. L. (2013) · Environmental Research · doi:10.1016/j.envres.2013.01.006 · Cited by 81 · see citing works

The novel inflammatory cytokine high mobility group box protein 1 (HMGB1) is expressed by human term placenta

Holmlund, U., Wähämaa, H., Bachmayer, N., Bremme, K., Sverremark‐Ekström, E., & Palmblad, K. (2007) · Immunology · doi:10.1111/j.1365-2567.2007.02662.x · Cited by 83 · see citing works

Maternal prepregnancy overweight and obesity and the risk of preeclampsia: A meta-analysis of cohort studies

He, X.-J., Dai, R.-X., & Hu, C.-L. (2020) · Obesity Research & Clinical Practice · doi:10.1016/j.orcp.2020.01.004 · Cited by 84 · see citing works

Oxidative Stress and the Induction of Cyclooxygenase Enzymes and Apoptosis in the Murine Placenta

Burdon, C., Mann, C., Cindrova-Davies, T., Ferguson-Smith, A. C., & Burton, G. J. (2007) · Placenta · doi:10.1016/j.placenta.2006.12.001 · Cited by 71 · see citing works

Environmental contaminants and preeclampsia: a systematic literature review

Rosen, E. M., Muñoz, M. I., McElrath, T., Cantonwine, D. E., & Ferguson, K. K. (2018) · Journal of Toxicology and Environmental Health, Part B · doi:10.1080/10937404.2018.1554515 · Cited by 74 · see citing works

Decreased expression of the angiogenic regulators CYR61 (CCN1) and NOV (CCN3) in human placenta is associatedwith pre-eclampsia

Gellhaus, A. (2006) · Molecular Human Reproduction · doi:10.1093/molehr/gal044 · Cited by 72 · see citing works

Fetal-derived adrenomedullin mediates the innate immune milieu of the placenta

Li, M., Schwerbrock, N. M. J., Lenhart, P. M., Fritz-Six, K. L., Kadmiel, M., Christine, K. S., Kraus, D. M., Espenschied, S. T., Willcockson, H. H., Mack, C. P., et al. (2013) · Journal of Clinical Investigation · doi:10.1172/jci67039 · Cited by 65 · see citing works

miR-34a expression, epigenetic regulation, and function in human placental diseases

Doridot, L., Houry, D., Gaillard, H., Chelbi, S. T., Barbaux, S., & Vaiman, D. (2014) · Epigenetics · doi:10.4161/epi.26196 · Cited by 65 · see citing works

Endometrial secretions: creating a stimulatory microenvironment within the human early placenta and implications for the aetiopathogenesis of preeclampsia

Burton, G. J., Scioscia, M., & Rademacher, T. W. (2011) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2011.02.005 · Cited by 64 · see citing works

Placental invasion, preeclampsia risk and adaptive molecular evolution at the origin of the great apes: Evidence from genome-wide analyses

Crosley, E. J., Elliot, M. G., Christians, J. K., & Crespi, B. J. (2013) · Placenta · doi:10.1016/j.placenta.2012.12.001 · Cited by 62 · see citing works

A review of inter- and intraspecific variation in the eutherian placenta

Gundling, W. E., & Wildman, D. E. (2015) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2014.0072 · Cited by 58 · see citing works

Full-length human placental sFlt-1-e15a isoform induces distinct maternal phenotypes of preeclampsia in mice

Szalai, G., Romero, R., Chaiworapongsa, T., Xu, Y., Wang, B., Ahn, H., Xu, Z., Chiang, P. J., Sundell, B., Wang, R., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0119547 · Cited by 46 · see citing works

Activation of villous trophoblastic p38 and ERK1/2 signaling pathways in preterm preeclampsia and HELLP syndrome

Szabo, S., Mody, M., Romero, R., Xu, Y., Karaszi, K., Mihalik, N., Xu, Z., Bhatti, G., Fule, T., Hupuczi, P., et al. (2015) · Pathology & Oncology Research · doi:10.1007/s12253-014-9872-9 · Cited by 45 · see citing works

Fully Automated 3-D Ultrasound Segmentation of the Placenta, Amniotic Fluid, and Fetus for Early Pregnancy Assessment

Looney, P., Yin, Y., Collins, S. L., Nicolaides, K. H., Plasencia, W., Molloholli, M., Natsis, S., & Stevenson, G. N. (2021) · IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control · doi:10.1109/tuffc.2021.3052143 · Cited by 40 · see citing works

The Circulating Proangiogenic Factors CYR61 (CCN1) and NOV (CCN3) Are Significantly Decreased in Placentae and Sera of Preeclamptic Patients

Gellhaus, A., Schmidt, M., Dunk, C., Lye, S. J., & Winterhager, E. (2007) · Reproductive Sciences · doi:10.1177/1933719107309816 · Cited by 37 · see citing works

Genome-wide expression profiling of placentas in the p57Kip2 model of pre-eclampsia

Knox, K. S., & Baker, J. C. (2007) · MHR: Basic science of reproductive medicine · doi:10.1093/molehr/gal116 · Cited by 33 · see citing works

Automated Placenta Segmentation with a Convolutional Neural Network Weighted by Acoustic Shadow Detection

Hu, R., Singla, R., Yan, R., Mayer, C., & Rohling, R. N. (2019) · 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2019.8857448 · Cited by 27 · see citing works

MIR146A rs2910164 (G/C) Polymorphism is Associated with Incidence of Preeclampsia in Gestational Diabetes Patients

Abo-Elmatty, D. M., & Mehanna, E. T. (2019) · Biochemical Genetics · doi:10.1007/s10528-018-9886-1 · Cited by 18 · see citing works