Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions

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    Fengjiao Sun, Yun Lei, Jingjing You, Chen Li, Linshan Sun, Jacob C. Garza, Di Zhang, Ming Guo, Philipp E. Scherer, Daniel J. Lodge et al. · 2018 · Molecular Psychiatry
  2. Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by upregulating AdipoRs/PPARα signaling in ob/ob and db/db transgenic mouse models
    Ahmad, Ashfaq, Ali, Tahir, Kim, Min Woo, Khan, Amjad, Jo, Myeung Hoon, Rehman, Shafiq Ur, Khan, Muhammad Sohail, Abid, Noman Bin, Khan, Mehtab, Ullah, Rahat et al. · 2019 · Metabolism
  3. Yerba mate extract (Ilex paraguariensis) attenuates both central and peripheral inflammatory effects of diet-induced obesity in rats
    Gustavo D. Pimentel, Fábio Santos Lira, José Cesar Rosa Neto, Aline Venticinque Caris, Fernanda Pinheiro, Eliane B. Ribeiro, Cláudia Maria Oller do Nascimento, Lila Missae Oyama · 2012 · The Journal of Nutritional Biochemistry
  4. Activation of Peroxisome Proliferator-Activated Receptor Gamma by Rosiglitazone Increases Sirt6 Expression and Ameliorates Hepatic Steatosis in Rats
    Soo Jin Yang, Jung Mook Choi, Seoung Wan Chae, Won Jun Kim, Se Eun Park, Eun‐Jung Rhee, Won‐Young Lee, Ki Won Oh, Sung Woo Park, Sun Woo Kim et al. · 2011 · PLoS ONE
  5. Protective effects of adiponectin against renal ischemia‐reperfusion injury via prostacyclin‐PPARα‐Heme oxygenase‐1 signaling pathway
    Ching‐Feng Cheng, Wei‐Shiung Lian, Sung‐Ho Chen, Pei‐Fen Lai, Hsiao‐Fen Li, Yi‐Fan Lan, Winston Teng‐Kuei Cheng, Heng Lin · 2011 · Journal of Cellular Physiology
  6. Developmental Programming: Effect of Prenatal Steroid Excess on Intraovarian Components of Insulin Signaling Pathway and Related Proteins in Sheep1
    Hugo H. Ortega, Florencia Rey, M.M.L. Velázquez, Vasantha Padmanabhan · 2010 · Biology of Reproduction
  7. The immunopathogenesis of alcoholic and nonalcoholic steatohepatitis: two triggers for one disease?
    Luca V. C. Valenti, Anna Ludovica Fracanzani, Silvia Rossana Fargion · 2009 · Seminars in Immunopathology
  8. Molecular Mechanisms in Skeletal Muscle Underlying Insulin Resistance in Women Who Are Lean With Polycystic Ovary Syndrome.
    Solvejg Hansen, P. Svendsen, J. Jeppesen, Louise D. Høeg, N. R. Andersen, J. M. Kristensen, L. Nilas, Annemarie Lundsgaard, J. Wojtaszewski, S. Madsbad et al. · 2018 · Journal of Clinical Endocrinology and Metabolism
  9. Adiponectin gene polymorphisms associated with diabetes mellitus: A descriptive review
    Mithu Howlader, Mst Irin Sultana, Farzana Akter, Md. Murad Hossain · 2021 · Heliyon
  10. Crosstalk between EET and HO-1 downregulates Bach1 and adipogenic marker expression in mesenchymal stem cell derived adipocytes
    Luca Vanella, Dong‐Hyun Kim, Komal Sodhi, Ignazio Alberto Barbagallo, Angela Burgess, John Russell Falck, Michal Laniado Schwartzman, Nader G. Abraham · 2011 · Prostaglandins & Other Lipid Mediators
  11. Beyond Fat Mass: Exploring the Role of Adipokines in Rheumatic Diseases
    Morena Scotece, Javier Conde, Rodolfo Gómez, Veronica López, Francisca Lago, Juan Jesús Gómez-Reino, Oreste Gualillo · 2011 · The Scientific World JOURNAL
  12. Daidzein regulates proinflammatory adipokines thereby improving obesity‐related inflammation through PPARγ
    Yuri Saho Sakamoto, A. Naka, Nozomi Ohara, Kazuo N. Kondo, Kaoruko Iida · 2013 · Molecular Nutrition & Food Research
  13. Adiponectin-stimulated CXCL8 release in primary human hepatocytes is regulated by ERK1/ERK2, p38 MAPK, NF-κB, and STAT3 signaling pathways
    Josef Wanninger, Markus Neumeier, Johanna Weigert, Sabrina Bauer, Thomas S. Weiß, Andréas Schäffler, Corinna Krempl, Cornelia Bleyl, Charalampos Aslanidis, Jürgen Schölmerich et al. · 2009 · American Journal of Physiology-Gastrointestinal and Liver Physiology
  14. Adiponectin and Its Mimics on Skeletal Muscle: Insulin Sensitizers, Fat Burners, Exercise Mimickers, Muscling Pills … or Everything Together?
    Abou-Samra, Michel, Selvais, Camille M., Dubuisson, Nicolas, Brichard, Sonia M. · 2020 · International Journal of Molecular Sciences
  15. Non-alcoholic fatty liver disease: An overview of risk factors, pathophysiological mechanisms, diagnostic procedures, and therapeutic interventions
    Samar H. Gerges, Sara A. Wahdan, Doaa A. Elsherbiny, Ebtehal El‐Demerdash · 2021 · Life Sciences
  16. Association of Adipose Tissue and Adipokines with Development of Obesity-Induced Liver Cancer
    Yetirajam Rajesh, Devanand Sarkar · 2021 · International Journal of Molecular Sciences
  17. New Insights into AMPK, as a Potential Therapeutic Target in Metabolic Dysfunction-Associated Steatotic Liver Disease and Hepatic Fibrosis
    Hoon An, Yerin Jang, Jung-In Choi, Juhee Hur, Seojeong Kim, Youngjoo Kwon · 2024 · Biomolecules & Therapeutics
  18. Involvement of Endothelial Apoptosis Underlying Chronic Obstructive Pulmonary Disease–like Phenotype in Adiponectin-null Mice: Implications for Therapy
    Kaori Nakanishi, Yoshito Takeda, Satoshi Tetsumoto, Takeo Iwasaki, Kazuyuki Tsujino, Hanako Kuhara, Yingji Jin, Izumi Nagatomo, Hiroshi Kida, Sho Goya et al. · 2011 · American Journal of Respiratory and Critical Care Medicine
  19. CNS-targets in control of energy and glucose homeostasis
    André Kleinridders, A. Christine Könner, Jens C. Brüning · 2009 · Current Opinion in Pharmacology
  20. Control of glycogen synthase through ADIPOR1-AMPK pathway in renal distal tubules of normal and diabetic rats
    Philippe Cammisotto, Irene Londoño, Diane Gingras, Moı̈se Bendayan · 2008 · American Journal of Physiology-Renal Physiology
  21. Suppression of adiponectin receptor 1 promotes memory dysfunction and Alzheimer’s disease-like pathologies
    Min Woo Kim, Noman Bin Abid, Min Gi Jo, Min Gi Jo, Gwang Ho Yoon, Myeong Ok Kim · 2017 · Scientific Reports
  22. Adipokines and Aging: Findings From Centenarians and the Very Old
    Arai, Yasumichi, Kamide, Kei, Hirose, Nobuyoshi · 2019 · Frontiers in Endocrinology
  23. Physiological role of adiponectin in different tissues: a review
    Saeed Esmaili, Mina Hemmati, Mehdi Karamian · 2018 · Archives of Physiology and Biochemistry
  24. Adiponectin Alleviates Diet-Induced Inflammation in the Liver by Suppressing MCP-1 Expression and Macrophage Infiltration
    Jiyoon Ryu, Jason T. Hadley, Zhi Li, Feng Dong, Huan Ying Xu, Xiaoban Xin, Ye Zhang, Cang Chen, Senlin Li, Xiaoning Guo et al. · 2021 · Diabetes
  25. Adiponectin and Adiponectin Receptors in Atherosclerosis
    Ioanna Gianopoulos, Christos Socrates Mantzoros, Stella Styliani Daskalopoulou · 2024 · Endocrine Reviews
  26. Stimulated release of a hyperpolarizing factor ( ADHF ) from mesenteric artery perivascular adipose tissue: involvement of myocyte BKCa channels and adiponectin
    A.H. Weston, Iris Egner, Y Dong, E. L. Porter, Anthony Michael Heagerty, G. Edwards · 2013 · British Journal of Pharmacology
  27. Milk-Derived Peptides, Val-Pro-Pro and Ile-Pro-Pro, Attenuate Atherosclerosis Development in Apolipoprotein E–Deficient Mice: A Preliminary Study
    Teppei Nakamura, Tatsuhiko Hirota, Katsura Mizushima, Kohji Ohki, Yuji Naito, Naoyuki Yamamoto, Toshikazu Yoshikawa · 2013 · Journal of Medicinal Food
  28. Globular adiponectin induces differentiation and fusion of skeletal muscle cells
    Fiaschi, Tania, Cirelli, Domenico, Comito, Giuseppina, Gelmini, Stefania, Ramponi, Giampietro, Serio, Mario, Chiarugi, Paola · 2009 · Cell Research
  29. The adipose tissue production of adiponectin is increased in end-stage renal disease
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  30. Myosteatosis: Diagnosis, pathophysiology and consequences in metabolic dysfunction-associated steatotic liver disease
    Guillaume Hénin, Audrey Loumaye, Isabelle Anne Leclercq, Nicolas Lanthier · 2023 · JHEP Reports
  31. Adiponectin Receptors Form Homomers and Heteromers Exhibiting Distinct Ligand Binding and Intracellular Signaling Properties
    Farid Almabouada, Alberto Díaz‐Ruiz, Yoana Rabanal‐Ruiz, Juan R. Peinado, Rafael Vázquez‐Martínez, Marı́a M. Malagón · 2012 · Journal of Biological Chemistry
  32. Patterns of Adiponectin Expression in Term Pregnancy: Impact of Obesity
    Maricela Haghiac, Subhabrata Basu, Larraine Huston Presley, David Serre, Patrick M. Catalano, Sylvie Hauguel‐de Mouzon · 2014 · The Journal of Clinical Endocrinology & Metabolism
  33. Examining the Potential of Developing and Implementing Use of Adiponectin-Targeted Therapeutics for Metabolic and Cardiovascular Diseases
    Liu, Ying, Vu, Vivian, Sweeney, Gary · 2019 · Frontiers in Endocrinology
  34. AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin
    Mario Ruiz, Marcus Ståhlman, Jan Borén, Marc Pilon · 2019 · Journal of Lipid Research
  35. 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) Effect on Glucose Production, but Not Energy Metabolism, Is Independent of Hepatic AMPK in Vivo
    Clinton M. Hasenour, D. Emerson Ridley, Curtis C. Hughey, Freyja D. James, E. Patrick Donahue, Jane Shearer, Benoı̂t Viollet, Marc Foretz, David H. Wasserman · 2014 · Journal of Biological Chemistry
  36. Adiponectin oligomerization state and adiponectin receptors airway expression in chronic obstructive pulmonary disease
    Aurora Daniele, Anna De Rosa, Ersilia Nigro, Olga Scudiero, Mario Capasso, Mariorosario Masullo, Guglielmo de Laurentiis, Giovannangelo Oriani, Matteo Sofia, Andrea Bianco · 2012 · The International Journal of Biochemistry & Cell Biology
  37. Roles of leptin, adiponectin and resistin in the transcriptional regulation of steroidogenic genes contributing to decreased Leydig cells function in obesity
    Pauline Roumaud, Luc J. Martin · 2015 · Hormone Molecular Biology and Clinical Investigation
  38. Circulating adipokines and mRNA expression in adipose tissue and the placenta in women with gestational diabetes mellitus
    Panayoula C. Tsiotra, Panagiotis Halvatsiotis, Konstantinos Patsouras, Eirini Maratou, George Salamalekis, S. Raptis, George Dimitriadis, Eleni I. Boutati · 2018 · Peptides
  39. Adiponectin as an Anti-fibrotic and Anti-inflammatory Adipokine in the Liver
    Pil‐Hoon Park, Carlos Sanz‐García, Laura E. Nagy · 2015 · Current Pathobiology Reports
  40. Adiponectin receptor agonist ameliorates cardiac lipotoxicity via enhancing ceramide metabolism in type 2 diabetic mice
    Yaeni Kim, Ji Hee Lim, Eun Nim Kim, Yu Ah Hong, Hun‐Jun Park, Sungjin Chung, Bum Soon Choi, Yong‐Soo Kim, Ji Yong Park, Hye Won Kim et al. · 2022 · Cell Death and Disease
  41. Adiponectin: friend or foe in obesity and inflammation
    Liping Luo, Meilian Liu · 2022 · Medical Review
  42. Adiponectin stimulates phosphorylation of AMP-activated protein kinase α in renal glomeruli
    Philippe Cammisotto, Moı̈se Bendayan · 2008 · Journal of Molecular Histology
  43. Adiponectin stimulates prostaglandin E 2 production in rheumatoid arthritis synovial fibroblasts
    Natsuko Kusunoki, Kanako Kitahara, Fumiaki Kojima, Nahoko Tanaka, Kaichi Kaneko, Hirahito Endo, Toru Suguro, Shinichi Kawai · 2010 · Arthritis & Rheumatism
  44. Adipokines as drug targets in joint and bone disease
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  46. Adiponectin alleviates exacerbation of airway inflammation and oxidative stress in obesity-related asthma mice partly through AMPK signaling pathway
    Lili Zhu, Xiuzhen Chen, Lei Chong, Ludan Kong, Shunhang Wen, Hailin Zhang, Weixi Zhang, Changchong Li · 2018 · International Immunopharmacology
  47. Adipocytokines and obesity-linked disorders.
    Noriyuki Ouchi, Koji Ohashi, Rei Shibata, Toyoaki Murohara · 2012 · PubMed Central
  48. Cross-Talk between Adiponectin and IGF-IR in Breast Cancer
    Loredana Mauro, Giuseppina Daniela Naimo, Emilia Ricchio, Maria Luisa Panno, Sebastiano Andò · 2015 · Frontiers in Oncology
  49. Globular Adiponectin Limits Microglia Pro-Inflammatory Phenotype through an AdipoR1/NF-κB Signaling Pathway
    Sarah Nicolas, Julie Cazareth, Hadi Zarif, Alice Guyon, Catherine Heurteaux, Joëlle Chabry, Agnès Petit-Paitel · 2017 · Frontiers in Cellular Neuroscience
  50. AdipoRon improves cognitive dysfunction of Alzheimer's disease and rescues impaired neural stem cell proliferation through AdipoR1/AMPK pathway.
    Bin Liu, Jing Liu, Jian-Gong Wang, Cuilan Liu, Hai-jing Yan · 2020 · Experimental Neurology
  51. Overexpression of the Adiponectin Receptor AdipoR1 in Rat Skeletal Muscle Amplifies Local Insulin Sensitivity
    S. A. Patel, Kyle L. Hoehn, Robert Lawrence, L. Sawbridge, N. A. Talbot, Jose Luis Tomsig, Nigel A. Turner, Gregory James Cooney, Jonathan P. Whitehead, Edward W. Kraegen et al. · 2012 · Endocrinology
  52. ERp46 binds to AdipoR1, but not AdipoR2, and modulates adiponectin signalling
    Hayley K. Charlton, Julie A. Webster, Sarah Krüger, Fiona Simpson, Ayanthi A. Richards, Jonathan P. Whitehead · 2010 · Biochemical and Biophysical Research Communications
  53. Obesity: Scope, Lifestyle Interventions, and Medical Management
    Benjamin J. McCafferty, James O. Hill, Andrew John Gunn · 2020 · Techniques in vascular and interventional radiology
  54. Adiponectin Receptor Signaling: A New Layer to the Current Model
    Takashi Kadowaki, Toshimasa Yamauchi · 2011 · Cell Metabolism
  55. Adiponectin increases macrophages cholesterol efflux and suppresses foam cell formation in patients with type 2 diabetes mellitus
    Min Wang, Duan Wang, Yuhua Zhang, Xiaoming Wang, Yan Liu, Min Xia · 2013 · Atherosclerosis
  56. Peripheral signalling involved in energy homeostasis control
    Andoni Lancha, Gema Frühbeck, Javier Gómez‐Ambrosi · 2012 · Nutrition Research Reviews
  57. Effects of nicotine on homeostatic and hedonic components of food intake
    Andrea Stojakovic, Enma Verónica Paez Espinosa, Osman T Farhad, Kabirullah Lutfy · 2017 · Journal of Endocrinology
  58. Adipokines in rheumatoid arthritis
    Elis Carolina de Souza Fatel, Flávia Troncon Rosa, Andréa Name Colado Simão, Isaías Dichi · 2018 · Revista Brasileira de Reumatologia
  59. Cardiometabolic effects of adiponectin
    Jennifer Parker, Kenneth X. Walsh · 2013 · Best Practice & Research Clinical Endocrinology & Metabolism
  60. Promotion of adiponectin multimerization by emodin: A novel AMPK activator with PPARγ‐agonist activity
    Zhifen Chen, Lu Zhang, Junyang Yi, Zhuanbo Yang, Zhijie Zhang, Zhen Li · 2012 · Journal of Cellular Biochemistry
  61. Adiponectin: An Attractive Marker for Metabolic Disorders in Chronic Obstructive Pulmonary Disease (COPD)
    Andrea Bianco, Gennaro Mazzarella, Viviana Turchiarelli, Ersilia Nigro, Graziamaria Corbi, Olga Scudiero, Matteo Sofia, Aurora Daniele · 2013 · Nutrients
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  63. Adiponectin Expression Protects against Angiotensin II-Mediated Inflammation and Accelerated Atherosclerosis
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  64. Insulin-sensitizing properties of adiponectin
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  65. Skeletal muscle as a therapeutic target for delaying type 1 diabetic complications
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  66. Role of Adipokines in Atherosclerosis: Interferences with Cardiovascular Complications in Rheumatic Diseases
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  69. Circulating adiponectin and adiponectin receptor expression in skeletal muscle: effects of exercise
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  70. Low plasma adiponectin concentration is associated with myocardial infarction in young individuals
    Jonas Persson, Kenneth A. Lindberg, Thomas P. Gustafsson, Per Olof Eriksson, Gabrielle Paulsson‐Berne, Pia Lundman · 2010 · Journal of Internal Medicine
  71. Adiponectin-derived active peptide ADP355 exerts anti-inflammatory and anti-fibrotic activities in thioacetamide-induced liver injury
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  72. Expression of lipid metabolism genes provides new insights into intramuscular fat deposition in Laiwu pigs
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  73. Recent advances in the measurement of adiponectin isoform distribution
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  74. Adipokines and Hepatic Insulin Resistance
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  75. Adiponectin potentiates the acute effects of leptin in arcuate Pomc neurons
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  76. The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids
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  82. Glucose level determines excitatory or inhibitory effects of adiponectin on arcuate POMC neuron activity and feeding
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  88. Identification of Adiponectin Receptor Agonist Utilizing a Fluorescence Polarization Based High Throughput Assay
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  89. Insights into the Role of PPARβ/δ in NAFLD
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  90. Adipokines and Redox Signaling: Impact on Fatty Liver Disease
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  91. Impact of Small-Molecule Glucokinase Activator on Glucose Metabolism and β-Cell Mass
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  93. Insulin decreases myocardial adiponectin receptor 1 expression via PI3K/Akt and FoxO1 pathway
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