Delivery materials for siRNA therapeutics

Kanasty, Rosemary, Dorkin, Joseph Robert, Vegas, Arturo, Anderson, Daniel·2013·Nature Materials

DOI 10.1038/nmat3765

Cited by (1,002)

Items 501–600 of 1,002

Targeted degradation of extracellular secreted and membrane proteins
Xuankun Chen, Yaxian Zhou, Yuan Zhao, Weiping Tang · 2023 · Trends in Pharmacological Sciences
Principles of lipid nanoparticle design for mRNA delivery
Yiran Zhang, Xinyue Zhang, Yongsheng Gao, Shuai Liu · 2024 · BMEMat
Nanomedicine in the development of anti-HIV microbicides
José das Neves, Rute Nunes, Francisca Rodrigues, Bruno Filipe Carmelino Cardoso Sarmento · 2016 · Advanced Drug Delivery Reviews
Formation and characterization of β-cyclodextrin (β-CD) – polyethyleneglycol (PEG) – polyethyleneimine (PEI) coated Fe3O4 nanoparticles for loading and releasing 5-Fluorouracil drug
G. Prabha, Vairamuthu Raj · 2016 · Biomedicine & Pharmacotherapy
siRNA-Loaded Polyion Complex Micelle Decorated with Charge-Conversional Polymer Tuned to Undergo Stepwise Response to Intra-Tumoral and Intra-Endosomal pHs for Exerting Enhanced RNAi Efficacy
Montira Tangsangasaksri, Hiroyasu Takemoto, Mitsuru Naito, Yoshinori Maeda, Daiki Sueyoshi, Hyun Jin Kim, Yutaka Miura, Jooyeon Ahn, Ryota Azuma, Nobuhiro Nishiyama et al. · 2015 · Biomacromolecules
Lipid-Based Liquid Crystalline Nanoparticles Facilitate Cytosolic Delivery of siRNA via Structural Transformation
Shufang He, Weiwei Fan, Na Wu, Jingjing Zhu, Yunqiu Miao, Xiaran Miao, Feifei Li, Xinxin Zhang, Yong Gan · 2018 · Nano Letters
DNA nanoclew templated spherical nucleic acids for siRNA delivery
Weimin Ruan, Meng Zheng, Yang An, Yuanyuan Liu, David B. Lovejoy, Mingcong Hao, Yan Zou, Albert Lee, Shu Yang, Yiqing Lu et al. · 2018 · Chemical Communications
Engineered nanoparticles for systemic siRNA delivery to malignant brain tumours
Johan E. Karlsson, Yuan Rui, Kristen Kozielski, Amanda L. Placone, Olivia Choi, Stephany Y. Tzeng, Jayoung Kim, Jamal J. Keyes, Max I. Bogorad, Kathleen L. Gabrielson et al. · 2019 · Nanoscale
Small interfering RNA from the lab discovery to patients' recovery
Marie Caillaud, Mévidette El Madani, Liliane Massaad-Massade · 2020 · Journal of Controlled Release
Intraventricular Delivery of siRNA Nanoparticles to the Central Nervous System
Shyam, Rishab, Ren, Yong, Lee, Jason, Braunstein, Kerstin E, Mao, Hai-Quan, Wong, Philip C · 2015 · Molecular Therapy - Nucleic Acids
The Application of Nanoparticles in Diagnosis and Treatment of Kidney Diseases
Patrycja Paluszkiewicz, Adrian Martuszewski, Natalia Zaręba, Kamila Wala, Mirosław Banasik, Marta Kepinská · 2021 · International Journal of Molecular Sciences
Overcoming Pharmaceutical Bottlenecks for Nucleic Acid Drug Development
Mei Lu, Haonan Xing, Aiping Zheng, Yuanyu Huang, Xing‐Jie Liang · 2023 · Accounts of Chemical Research
Nanobiomaterial vectors for improving gene editing and gene therapy
Shao Wei Hu, Tao Ding, Honghai Tang, Huiping Guo, Wenguo Cui, Yilai Shu · 2023 · Materials Today
Multifunctional nanocomposites modulating the tumor microenvironment for enhanced cancer immunotherapy
Prashant Sharma, Mario Otto · 2023 · Bioactive Materials
mRNA vaccines: a new era in vaccine development
Shubhra Chandra, Jennifer C Wilson, David M. Good, Ming Qian Wei · 2024 · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics
Nanoparticle-Mediated Delivery of SiRNA for Effective Lung Cancer Therapy
Young‐Dong Kim, Tae‐Eun Park, Bijay Singh, Sushila Maharjan, Yun‐Jaie Choi, Pill‐Hoon Choung, Rohidas B. Arote, Chong‐Su Cho · 2015 · Nanomedicine
Advances in an active and passive targeting to tumor and adipose tissues
Yu Sakurai, Kazuaki Kajimoto, Hiroto Hatakeyama, Hideyoshi Harashima · 2014 · Expert Opinion on Drug Delivery
Photoluminescent F-doped carbon dots prepared by ring-opening reaction for gene delivery and cell imaging
Tianying Luo, Xi He, Ji Zhang, Pïng Chen, Yanhong Liu, Haijiao Wang, Xiao‐Qi Yu · 2018 · RSC Advances
Delivery of small interfering RNA against Nogo-B receptor via tumor-acidity responsive nanoparticles for tumor vessel normalization and metastasis suppression
Bin Wang, Yanping Ding, Xiaozheng Zhao, Xuexiang Han, Na Yang, Yinlong Zhang, Ying Zhao, Xiao Zhao, Mohammad Taleb, Qing Miao et al. · 2018 · Biomaterials
Rescue the retina after the ischemic injury by polymer-mediated intracellular superoxide dismutase delivery
Xujiao Zhou, Jia Lv, Gang� Li, Tingting Qian, Hao Jiang, Jianjiang Xu, Yiyun Cheng, Jiaxu Hong · 2020 · Biomaterials
Lipid Nanoparticles for Nucleic Acid Delivery to Endothelial Cells
Gary W. Liu, Edward B. Guzman, Nandita Menon, Róbert Langer · 2023 · Pharmaceutical Research
Emerging frontiers in drug delivery with special focus on novel techniques for targeted therapies
Ling Yu, Shengmao Liu, Shengnan Jia, Feng Xu · 2023 · Biomedicine & Pharmacotherapy
Smart Manganese Dioxide-Based Lanthanide Nanoprobes for Triple-Negative Breast Cancer Precise Gene Synergistic Chemodynamic Therapy
Liyan Ming, Liang Song, Jixuan Xu, Ruoping Wang, Junpeng Shi, Min Chen, Yun Zhang · 2021 · ACS Applied Materials & Interfaces
Old age as a risk factor for liver diseases: Modern therapeutic approaches
Milena Georgieva, Charilaos Xenodochidis, Natalia A. Krasteva · 2023 · Experimental Gerontology
Therapeutic Applications of an Expanded Genetic Code
Sophie B. Sun, Peter G. Schultz, Chan Hyuk Kim · 2014 · ChemBioChem
Niosomes based on synthetic cationic lipids for gene delivery: the influence of polar head-groups on the transfection efficiency in HEK-293, ARPE-19 and MSC-D1 cells
E. Ojeda, Gustavo Puras, Mireia Agirre, Jon Zárate Sesma, Santiago Grijalvo, Ramón Pons, Ramón Eritja, Gema Martı́nez, Cristina Soto‐Sánchez, Eduardo Fernández et al. · 2014 · Organic & Biomolecular Chemistry
Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis
Pyoung Oh Yoon, Jin Wook Park, Chang‐Min Lee, Sung Hwan Kim, Han‐Na Kim, Youngho Ko, Seon Joo Bae, Sung‐Il Yun, Jun Hong Park, Taewoo Kwon et al. · 2016 · Journal of Biological Chemistry
Systemic delivery of siRNA by actively targeted polyion complex micelles for silencing the E6 and E7 human papillomavirus oncogenes
Haruka Nishida, Yoko Matsumoto, Kei Kawana, R. James Christie, Mitsuru Naito, Beob Soo Kim, Kazuko Toh, Hyun Su Min, Yu Yi, Yu Matsumoto et al. · 2016 · Journal of Controlled Release
Silencing CCR2 in Macrophages Alleviates Adipose Tissue Inflammation and the Associated Metabolic Syndrome in Dietary Obese Mice
Jong-Kil Kim, Kunho Chung, Changseon Choi, Jagadish Beloor, Irfan Ullah, Nahyeon Kim, Kuen Yong Lee, Sang‐Kyung Lee, Priti Kumar · 2016 · Molecular Therapy — Nucleic Acids
The Role of micro RNAs in Breast Cancer Metastasis: Preclinical Validation and Potential Therapeutic Targets
Ulrich H. Weidle, Steffen Dickopf, Corinna Hintermair, Gwendlyn Kollmorgen, Fabian Birzele, Ulrich Brinkmann · 2018 · Cancer Genomics & Proteomics
Lipid-Based Vectors for Therapeutic mRNA-Based Anti-Cancer Vaccines
Maria L. Guevara, Stefano Persano, Francesca Persano · 2019 · Current Pharmaceutical Design
Clinical Translation of Self‐Assembled Cancer Nanomedicines
Peng Mi, Kanjiro Miyata, Kazunori Kataoka, Horacio Cabral · 2020 · Advanced Therapeutics
Hepatocyte targeting via the asialoglycoprotein receptor
Ramírez-Cortés, Fabricio, Ménová, Petra · 2025 · RSC Medicinal Chemistry
Rationale and Application of PEGylated Lipid-Based System for Advanced Target Delivery of siRNA
Xuemei Ge, Lijuan Chen, Bo Zhao, Weien Yuan · 2021 · Frontiers in Pharmacology
Targeted Therapy in Cardiovascular Disease: A Precision Therapy Era
Mengda Xu, Kailun Zhang, Jiangping Song · 2021 · Frontiers in Pharmacology
Molecularly engineered siRNA conjugates for tumor-targeted RNAi therapy
Jong Won Lee, Ji‐Won Choi, Yeonho Choi, Kwangmeyung Kim, Yoosoo Yang, Sun Hwa Kim, Hong Yeol Yoon, Ick Chan Kwon · 2022 · Journal of Controlled Release
Dendrimer–siRNA Conjugates for Targeted Intracellular Delivery in Glioblastoma Animal Models
Wathsala Liyanage, Tony Wu, Sujatha Kannan, Rangaramanujam M. Kannan · 2022 · ACS Applied Materials & Interfaces
Triazine-modified dendrimer for efficient TRAIL gene therapy in osteosarcoma
Yu Wang, Lei Li, Naimin Shao, Zhiqi Hu, Hui Chen, Leqin Xu, Changping Wang, Yiyun Cheng, Jianru Xiao · 2015 · Acta Biomaterialia
Structure–activity relationship of dendrimers engineered with twenty common amino acids in gene delivery
Fei Wang, Ke Hu, Yiyun Cheng · 2015 · Acta Biomaterialia
Blocking Stemness and Metastatic Properties of Ovarian Cancer Cells by Targeting p70S6K with Dendrimer Nanovector-Based siRNA Delivery
Jing Ma, Shashwati Kala, Susan Yung, Tak Mao Chan, Yu Cao, Yifan Jiang, Xiaoxuan Liu, Suzanne Giorgio, Ling Peng, Alice S.T. Wong · 2017 · Molecular Therapy
Micelleplexes as nucleic acid delivery systems for cancer-targeted therapies
Miguel Pereira‐Silva, Ivana Jarak, Carmen Alvarez‐Lorenzo, Ángel Concheiro, Ana Cláudia Paiva‐Santos, Francisco Veiga, Ana Figueiras · 2020 · Journal of Controlled Release
Vaccination with Messenger RNA: A Promising Alternative to DNA Vaccination
István Tombácz, Drew Weissman, Norbert Pardi · 2020 · Methods in molecular biology
Development of EphA2 siRNA-loaded lipid nanoparticles and combination with a small‐molecule histone demethylase inhibitor in prostate cancer cells and tumor spheroids
Ezgi Öner, Mustafa Kotmakçı, Anne‐Marie Baird, Steven G. Gray, Bilge DEBELEÇ BÜTÜNER, Emir Bozkurt, Ayşe Gülten Kantarcı, Stephen P. Finn · 2021 · Journal of Nanobiotechnology
Improving the therapeutic efficiency of noncoding RNAs in cancers using targeted drug delivery systems
Rami M. Alzhrani, Hashem O. Alsaab, Alex Petrovici, Ketki Bhise, Kushal Vanamala, Samaresh Sau, Matthew J. Krinock, Arun K. Iyer · 2019 · Drug Discovery Today
Biomedical applications of nanomaterials in the advancement of nucleic acid therapy: Mechanistic challenges, delivery strategies, and therapeutic applications
Dr Krishna Yadav, Kantrol Kumar Sahu, Sucheta, S. Princely Ebenezer Gnanakani, Pavani Sure, R. Vijayalakshmi, V. D. Sundar, Versha Sharma, Ruchita Antil, Megha Jha et al. · 2023 · International Journal of Biological Macromolecules
Tetrahedral Framework Nucleic Acids Based Small Interfering RNA Targeting Receptor for Advanced Glycation End Products for Diabetic Complications Treatment
Zhengwen Cai, Yong Li, Long Bai, Jiangshan Xu, Zhiqiang Liu, Tianxu Zhang, Shaojingya Gao, Yunfeng Lin · 2023 · ACS Nano
Cancer Nanotherapeutics in Clinical Trials
Abigail K. R. Lytton‐Jean, Kevin J. Kauffman, James C. Kaczmarek, Róbert Langer · 2015 · Cancer treatment and research
Nano‐Self‐Assembly of Nucleic Acids Capable of Transfection without a Gene Carrier
Kwang Suk Lim, Daniel Y. Lee, Gabriel M. Valencia, Young-Wook Won, David A. Bull · 2015 · Advanced Functional Materials
Personalizing Biomaterials for Precision Nanomedicine Considering the Local Tissue Microenvironment
Nuria Oliva, Shimon A. Unterman, Yi Zhang, João Conde, Hyun Seok Song, Natalie Artzi · 2015 · Advanced Healthcare Materials
Synthetic SiRNA Delivery: Progress and Prospects
Thomas C. Roberts, Kariem Ezzat, Samir EL Andaloussi, Marc S. Weinberg · 2015 · Methods in molecular biology
A tumor-targeting cRGD-EGFR siRNA conjugate and its anti-tumor effect on glioblastoma in vitro and in vivo
Shuai He, Bohong Cen, Lumin Liao, Zhen Wang, Yixin Qin, Zhuomin Wu, Wenjie Liao, Zhongyi Zhang, Aimin Ji · 2017 · Drug Delivery
Polymer nanocarriers for MicroRNA delivery
Chintan H. Kapadia, Benjamin Luo, Megan N. Dang, N’Dea S. Irvin-Choy, Danielle M. Valcourt, Emily S. Day · 2019 · Journal of Applied Polymer Science
Efficient drug and gene delivery to liver fibrosis: rationale, recent advances, and perspectives
Somayeh Mahdinloo, Seyed Hossein Kiaie, Ala Amiri, Salar Hemmati, Hadi Valizadeh, Parvin Zakeri‐Milani · 2020 · Acta Pharmaceutica Sinica B
Pre-Clinical and Clinical Applications of Small Interfering RNAs (siRNA) and Co-Delivery Systems for Pancreatic Cancer Therapy
Sepideh Mirzaei, Mohammad Hossein Gholami, Hui Li Ang, Farid Hashemi, Ali Zarrabi, Amirhossein Zabolian, Kiavash Hushmandi, Masoud Delfi, Haroon Zaman Khan, Milad Ashrafizadeh et al. · 2021 · Cells
Cationic cellulose nanocrystals complexed with polymeric siRNA for efficient anticancer drug delivery
Young Min Kim, Lawrence Yoon Suk Lee, Taehyung Kim, Kyungjik Yang, Keonwook Nam, Deokyeong Choe, Young Hoon Roh · 2020 · Carbohydrate Polymers
Suppression of lncRNA Gm47283 attenuates myocardial infarction via miR-706/ Ptgs2/ferroptosis axis
Feng Gao, Yongcheng Zhao, Bin Zhang, Chunwei Xiao, Zhanfa Sun, Yuan Gao, Xueyong Dou · 2022 · Bioengineered
CAR-T-Derived Extracellular Vesicles: A Promising Development of CAR-T Anti-Tumor Therapy
Sara Pagotto, Pasquale Simeone, Davide Brocco, Giulia Catitti, Domenico De Bellis, Simone Vespa, Natalia Di Pietro, Lisa Marinelli, Antonio Di Stefano, Serena Veschi et al. · 2023 · Cancers
Extracellular vesicles and their synthetic analogues in aging and age-associated brain diseases
Jayden A. Smith, Tommaso Leonardi, Bau‐Lin Huang, Nunzio Iraci, Beatriz Vega, Stefano Pluchino · 2014 · Biogerontology
Structure-property relationship for in vitro siRNA delivery performance of cationic 2-hydroxypropyl-β-cyclodextrin: PEG-PPG-PEG polyrotaxane vectors
Vivek D. Badwaik, Emilio Aicart, Yawo A. Mondjinou, Merrell A. Johnson, Valorie D. Bowman, David H. Thompson · 2016 · Biomaterials
Molecular Tuning of a Vitamin E-Scaffold pH-Sensitive and Reductive Cleavable Lipid-like Material for Accelerated in Vivo Hepatic siRNA Delivery
Hidetaka Akita, Yuki Noguchi, Hiroto Hatakeyama, Yusuke Sato, Kota Tange, Yuta Nakai, Hideyoshi Harashima · 2015 · ACS Biomaterials Science & Engineering
RNA Interference: Mechanisms, Technical Challenges, and Therapeutic Opportunities
Mouldy Sioud · 2014 · Methods in molecular biology
Biodegradable nanocarriers for small interfering ribonucleic acid (siRNA) co-delivery strategy increase the chemosensitivity of pancreatic cancer cells to gemcitabine
Chengbin Yang, Kok Ken Chan, Wen-Jen Lin, Alana Mauluidy Soehartono, Guimiao Lin, Hui Ting Toh, Ho Sup Yoon, Chih‐Kuang Chen, Ken‐Tye Yong · 2017 · Nano Research
Inhalable siRNA-loaded nano-embedded microparticles engineered using microfluidics and spray drying
Monica Agnoletti, Adam Bohr, Kaushik Thanki, Feng Wan, Xianghui Zeng, Johan Peter Boetker, Mingshi Yang, Camilla Foged · 2017 · European Journal of Pharmaceutics and Biopharmaceutics
The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy
Yeon‐Soo Seo, Young‐Hoon Kang · 2018 · Frontiers in Molecular Biosciences
Charge‐Conversion Strategies for Nucleic Acid Delivery
Kingshuk Dutta, Ritam Das, Jewel Medeiros, Pintu Kanjilal, S. Thayumanavan · 2021 · Advanced Functional Materials
Oral Delivery of Biologics in Inflammatory Bowel Disease Treatment
Wunan Zhang, Cécilia Bohns Michalowski, Ana Beloqui · 2021 · Frontiers in Bioengineering and Biotechnology
Gene therapy strategies for glaucoma from IOP reduction to retinal neuroprotection: Progress towards non-viral systems
Antoine M. Hakim, Benjamin Guido, Lokesh Narsineni, Ding-Wen Chen, Marianna Földvári · 2023 · Advanced Drug Delivery Reviews
Inverse Cubic and Hexagonal Mesophase Evolution within Ionizable Lipid Nanoparticles Correlates with mRNA Transfection in Macrophages
Haitao Yu, Joshua Iscaro, Brendan Dyett, Yiran Zhang, Susanne Seibt, Natalia P. Martínez, John White, Calum John Drummond, Steven Bozinovski, Jiali Zhai · 2023 · Journal of the American Chemical Society
Macrophage Notch Ligand Delta-Like 4 Promotes Vein Graft Lesion Development
Jun‐ichiro Koga, Toshiaki Nakano, James E. Dahlman, José Luiz de Figueiredo, Hengmin Zhang, Julius L. Decano, Omar F. Khan, Tomiharu Niida, Hiroshi Iwata, Jon Christopher Aster et al. · 2015 · Arteriosclerosis Thrombosis and Vascular Biology
Exploring the pH Sensitivity of Poly(allylamine) Phosphate Supramolecular Nanocarriers for Intracellular siRNA Delivery
Patrizia Andreozzi, Eleftheria Diamanti, Karen Rapp Py-Daniel, Paolin Rocio Cáceres‐Vélez, Chiara Martinelli, Νικόλαος Πολιτάκος, Ane Escobar, Marco Muzi-Falconi, Ricardo Bentes Azevedo, Sergio Enrique Moya · 2017 · ACS Applied Materials & Interfaces
Global MicroRNA Profiling in Human Bone Marrow Skeletal—Stromal or Mesenchymal–Stem Cells Identified Candidates for Bone Regeneration
Chi-Chih Chang, Morten Trillingsgaard Venø, Li Chen, Nicholas Ditzel, Dang Quang Svend Le, Philipp Dillschneider, Moustapha S Kassem, Jørgen Kjems · 2017 · Molecular Therapy
Targeted siRNA delivery using aptamer‐siRNA chimeras and aptamer‐conjugated nanoparticles
Padmanaban Sivakumar, Sumin Kim, Han Chang Kang, Min Suk Shim · 2018 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
A nanogel based oral gene delivery system targeting SUMOylation machinery to combat gut inflammation
Prabhu Srinivas Yavvari, Priyanka Verma, Salman Ahmad Mustfa, Sanjay Pal, Sandeep Kumar, Anand Kumar Awasthi, Vineet Ahuja, Chittur V. Srikanth, Aasheesh Srivastava, Avinash Bajaj · 2019 · Nanoscale
Switching the intracellular pathway and enhancing the therapeutic efficacy of small interfering RNA by auroliposome
Md. Nazir Hossen, Lin Wang, Harisha R. Chinthalapally, J. David Robertson, Kar-Ming A. Fung, Stefan Wilhelm, Magdalena Bieniasz, Resham Bhattacharya, Priyabrata Mukherjee · 2020 · Science Advances
Thiolated-Polymer-Based Nanoparticles as an Avant-Garde Approach for Anticancer Therapies—Reviewing Thiomers from Chitosan and Hyaluronic Acid
Roberto Grosso, M.‐Violante de‐Paz · 2021 · Pharmaceutics
Modulating intracellular pathways to improve non-viral delivery of RNA therapeutics
Thijs Van de Vyver, Stefaan C. De Smedt, Koen Raemdonck · 2021 · Advanced Drug Delivery Reviews
Stepwise responsive carboxymethyl chitosan-based nanoplatform for effective drug-resistant breast cancer suppression
Hui Peng, Lei Qiao, Guisong Shan, Min Gao, Ruijie Zhang, Xiaoqing Yi, Xiaoyan He · 2022 · Carbohydrate Polymers
Microbubble–Nanoparticle Complexes for Ultrasound-Enhanced Cargo Delivery
Rachel Chapla, Katherine T. Huynh, Carolyn E. Schutt · 2022 · Pharmaceutics
High‐Precision Synthesis of RNA‐Loaded Lipid Nanoparticles for Biomedical Applications
Hanjin Seo, Leekang Jeon, Jaeyeong Kwon, Hyomin Lee · 2023 · Advanced Healthcare Materials
Cabazitaxel-loaded human serum albumin nanoparticles combined with TGFβ-1 siRNA lipid nanoparticles for the treatment of paclitaxel-resistant non-small cell lung cancer
Tiantian Tan, Yuxin Feng, Weimin Wang, Rongrong Wang, Liyan Yin, Yiying Zeng, Zhaowu Zeng, Tian Xie · 2023 · Cancer Nanotechnology
Intra‐Articular Injection of Nanomaterials for the Treatment of Osteoarthritis: From Lubrication Function Restoration to Cell and Gene Therapy
Yinuo Yang, Hongyu Zhang · 2024 · Advanced Functional Materials
Structurally plastic peptide capsules for synthetic antimicrobial viruses
Valeria Castelletto, Emiliana De Santis, Hasan Alkassem, Baptiste Lamarre, James E. Noble, Santanu Ray, Angelo Bella, Jonathan R. Burns, Bart W. Hoogenboom, Maxim G. Ryadnov · 2015 · Chemical Science
Fluorinated peptide biomaterials
Janna N. Sloand, Michael A. Miller, Scott H. Medina · 2020 · Peptide Science
Anodic Substitution Reaction of Proline Derivatives Using the 2,4,6-Trimethoxyphenyl Leaving Group
Takao Shoji, Shokaku Kim, Keisuke Yamamoto, Tomomitsu Kawai, Yohei Okada, Kazuhiro Chiba · 2014 · Organic Letters
Polyethylene Glycol-Mediated Fusion of Extracellular Vesicles with Cationic Liposomes for the Design of Hybrid Delivery Systems
Dipanjan Mukherjee, Debashish Paul, Sushmita Sarker, Md. Nur Hasan, Ria Ghosh, Sujanthi Easwara Prasad, Praveen Kumar Vemula, Ranjan Das, Arghya Adhikary, Samir Kumar Pal et al. · 2021 · ACS Applied Bio Materials
Pancreatic cancer gene therapy using an siRNA-functionalized single walled carbon nanotubes (SWNTs) nanoplex
Tommy Anderson, Rui Hu, Chengbin Yang, Ho Sup Yoon, Ken‐Tye Yong · 2014 · Biomaterials Science
Peptide Nanofiber Complexes with siRNA for Deep Brain Gene Silencing by Stereotactic Neurosurgery
Mariarosa Mazza, Marilena Hadjidemetriou, Irene de Lázaro, Cyrill Bussy, Kostas Kostarelos · 2015 · ACS Nano
In Vivo Gene‐Silencing in Fibrotic Liver by siRNA‐Loaded Cationic Nanohydrogel Particles
Leonard Kaps, Lutz Nuhn, Misbah Aslam, Alexander Brose, Friedrich Foerster, Sebastian Rosigkeit, Patricia Renz, Rosario Heck, Yong Ook Kim, Ingo Lieberwirth et al. · 2015 · Advanced Healthcare Materials
The Niemann-Pick C1 Inhibitor NP3.47 Enhances Gene Silencing Potency of Lipid Nanoparticles Containing siRNA
Haitang Wang, Yuen Yi C. Tam, Sam Chen, Josh Zaifman, Roy van der Meel, Marco A. Ciufolini, Pieter R. Cullis · 2016 · Molecular Therapy
Enhanced Intracellular Delivery of siRNA by Controlling ATP‐Responsivity of Phenylboronic Acid‐Functionalized Polyion Complex Micelles
Mitsuru Naito, Naoto Yoshinaga, Takehiko Ishii, Akira Matsumoto, Yuji Miyahara, Kanjiro Miyata, Kazunori Kataoka · 2017 · Macromolecular Bioscience
A siRNA-induced peptide co-assembly system as a peptide-based siRNA nanocarrier for cancer therapy
Wenjun Li, Dongyuan Wang, Xiaodong Shi, Jingxu Li, Yue Ma, Yanding Wang, Tingting Li, Jianing Zhang, Rongtong Zhao, Zhiqiang Yu et al. · 2018 · Materials Horizons
Multiscale Modeling and Simulation of Nano‐Carriers Delivery through Biological Barriers—A Review
Xinghua Shi, Falin Tian · 2018 · Advanced Theory and Simulations
Nanoscopy for endosomal escape quantification
Teodora Andrian, Roger Riera, Sílvia Pujals, Lorenzo Albertazzi · 2020 · Nanoscale Advances
Minimal Physiologically Based Pharmacokinetic-Pharmacodynamic (mPBPK-PD) Model of N-Acetylgalactosamine–Conjugated Small Interfering RNA Disposition and Gene Silencing in Preclinical Species and Humans
Vivaswath S. Ayyar, Dawei Song, Songmao Zheng, Thomas Carpenter, Donald Heald · 2021 · Journal of Pharmacology and Experimental Therapeutics
Modern therapeutic approaches to liver-related disorders
Antoine Gardin, Katharina Remih, Emmanuel M. Gonzales, Emma Rachel Andersson, Pavel Strnad · 2022 · Journal of Hepatology
Smart nanomaterials for multimodal theranostics and tissue regeneration
Hyun Lee, Kyoung Sub Kim, Iman Zare, Seojoon Bang, Hyeong Seok Kang, Chan Ho Moon, Ju Yeong Gwon, Jong Hwa Seo, Hyojin Joo, YounHa Cho et al. · 2025 · Coordination Chemistry Reviews
Immunological and hematological toxicities challenging clinical translation of nucleic acid-based therapeutics
Marina A. Dobrovolskaia, Scott E. McNeil · 2015 · Expert Opinion on Biological Therapy
Theranostical nanosystem‐mediated identification of an oncogene and highly effective therapy in hepatocellular carcinoma
Yu Guo, Jing Wang, Lu Zhang, Shunli Shen, Ruomi Guo, Yang Yang, Wenjie Chen, Yiru Wang, Guihua Chen, Xintao Shuai · 2015 · Hepatology
Improvement of Doxorubicin Efficacy Using Liposomal Anti-Polo-like Kinase 1 siRNA in Human Renal Cell Carcinomas
Yu Sakurai, Hiroto Hatakeyama, Hidetaka Akita, Hideyoshi Harashima · 2014 · Molecular Pharmaceutics
Pre-administration of PepFect6-microRNA-146a nanocomplexes inhibits inflammatory responses in keratinocytes and in a mouse model of irritant contact dermatitis
Egon Urgard, Annely Lorents, Mariliis Klaas, Kärt Padari, Janeli Viil, Toomas Runnel, Kent Langel, Külli Kingo, Eric R. Tkaczyk, Ülo Langel et al. · 2016 · Journal of Controlled Release