Delivery materials for siRNA therapeutics

Cited by (1,002)

Items 801–900 of 1,002

1. Pharmaceutical applications of framework nucleic acids
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2. RNA Silencing in the Management of Dyslipidemias
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5. A fluorinated peptide with high serum- and lipid-tolerence for the delivery of siRNA drugs to treat obesity and metabolic dysfunction
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6. A Systematic Study of Unsaturation in Lipid Nanoparticles Leads to Improved mRNA Transfection In Vivo
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7. Bioinspired Spatiotemporal Management toward RNA Therapies
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8. Intracellular Delivery of Bioactive Cargos to Hard‐to‐Transfect Cells Using Carbon Nanosyringe Arrays under an Applied Centrifugal g‐Force
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9. Dendritic peptide bolaamphiphiles for siRNA delivery to primary adipocytes
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10. Peptide-based vectors: recent developments
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11. Polymers in the Co-delivery of siRNA and Anticancer Drugs for the Treatment of Drug-resistant Cancers
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12. Aptamer–siRNA Chimeras for HIV
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13. Engineered Histidine-Enriched Facial Lipopeptides for Enhanced Intracellular Delivery of Functional siRNA to Triple Negative Breast Cancer Cells
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14. Nanoharvesting of bioactive materials from living plant cultures using engineered silica nanoparticles
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16. Magnetic nanoparticles: A new diagnostic and treatment platform for rheumatoid arthritis
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17. Use, exposure and omics characterisation of potential hazard in nanomaterials
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18. Preparation of Inert Polystyrene Latex Particles as MicroRNA Delivery Vectors by Surfactant-Free RAFT Emulsion Polymerization
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19. Angiogenesis regulation by nanocarriers bearing RNA interference
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20. Synergistic anti-tumor effects of bevacizumab and tumor targeted polymerized VEGF siRNA nanoparticles
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21. Light-triggerable formulations for the intracellular controlled release of biomolecules
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22. Aqueous-Soluble, Acid-Transforming Chitosan for Efficient and Stimuli-Responsive Gene Silencing
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23. Y-Shaped Circular Aptamer–DNAzyme Conjugates for Highly Efficient in Vivo Gene Silencing
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24. Targeting activation of cGAS-STING signaling pathway by engineered biomaterials for enhancing cancer immunotherapy
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25. Nucleic acid combinations: A new frontier for cancer treatment
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26. Selective RNA interference and gene silencing using reactive oxygen species-responsive lipid nanoparticles
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27. Nonviral Nanoparticles for CRISPR-Based Genome Editing: Is It Just a Simple Adaption of What Have Been Developed for Nucleic Acid Delivery?
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28. Delivery of RNAi-Based Therapeutics for Bone Regeneration
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29. Ugi Reaction of Amino Acids: From Facile Synthesis of Polypeptoids to Sequence‐Defined Macromolecules
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30. Bottom-up strategies for the synthesis of peptide-based polymers
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31. Tetrahedral-Framework Nucleic Acids Carry Small Interfering RNA to Downregulate Toll-Like Receptor 2 Gene Expression for the Treatment of Sepsis
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32. Reprogrammed siTNFα/neutrophil cytopharmaceuticals targeting inflamed joints for rheumatoid arthritis therapy
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33. Nucleic acid-based artificial nanocarriers for gene therapy
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34. miR-29b defines the pro-/anti-proliferative effects of S100A7 in breast cancer
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35. Dual-functional lipid-like nanoparticles for delivery of mRNA and MRI contrast agents
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36. Targeting MUC 1 and JNK by RNA interference and inhibitor inhibit the development of hepatocellular carcinoma
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37. Negative regulation of cationic nanoparticle-induced inflammatory toxicity through the increased production of prostaglandin E2 via mitochondrial DNA-activated Ly6C+ monocytes
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38. Highly efficient gene release in spatiotemporal precision approached by light and pH dual responsive copolymers
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39. Proof of concept studies for siRNA delivery by nonionic surfactant vesicles: in vitro and in vivo evaluation of protein knockdown
    Mohammad A. Obeid, Christine Dufès, Sukrut Somani, Alexander Balfour Mullen, Rothwelle J. Tate, Valerie Anne Ferro · 2018 · Journal of Liposome Research
40. Stereoselective pH Responsive Peptide Dendrimers for siRNA Transfection
    Marc Heitz, Sacha Javor, Tamis Darbre, Jean‐Louis Reymond · 2019 · Bioconjugate Chemistry
41. Zwitterionic Polymer-Decorated Lipid Nanoparticles for mRNA Delivery in Mammalian Cells
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42. Peptide-Hydrogel Nanocomposites for Anti-Cancer Drug Delivery
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43. Enhancing cancer immunotherapy: Exploring strategies to target the PD-1/PD-L1 axis and analyzing the associated patent, regulatory, and clinical trial landscape
    Shilpa Devi, S. D. Singh, Ramesh Joga, Sharvari Y. Patil, Vakalapudi Meghana Devi, Sabnis Chetan Dushantrao, Falguni Dwivedi, Deepak Kumar Jindal, Deepak Kumar Jindal, Charan Singh et al. · 2024 · European Journal of Pharmaceutics and Biopharmaceutics
44. Nanomaterials-assisted gene editing and synthetic biology for optimizing the treatment of pulmonary diseases
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45. Mechanotransduction for therapeutic approaches: Cellular aging and rejuvenation
    Hye-Min Han, Su-Yeon Kim, Dong‐Hwee Kim · 2025 · APL Bioengineering
46. Oral delivery of shRNA based on amino acid modified chitosan for improved antitumor efficacy
    Hao Zheng, Cui Tang, Chunhua Yin · 2015 · Biomaterials
47. Inhibition of hypoxia-induced proliferation of pulmonary arterial smooth muscle cells by a mTOR siRNA-loaded cyclodextrin nanovector
    Xueping Liu, Guansong Wang, Zaichun You, Pin Qian, Huaping Chen, Yin Dou, Zhenghua Wei, Yan Xiang Chen, Chengde Mao, Jianxiang Zhang · 2014 · Biomaterials
48. The potential and advances in RNAi therapy: Chemical and structural modifications of siRNA molecules and use of biocompatible nanocarriers
    Min Kyung Joo, Ji Young Yhee, Sun Hwa Kim, Kwangmeyung Kim · 2014 · Journal of Controlled Release
49. Vitamin E-Labeled Polyethylenimine for in vitro and in vivo Gene Delivery
    Jin‐Xing Liu, Mengke Feng, Duanwei Liang, Jiali Yang, Xinjing Tang · 2016 · Biomacromolecules
50. Efficient Transfection of siRNA by Peptide Dendrimer–Lipid Conjugates
    Albert Kwok, Gabriela A. Eggimann, Marc Heitz, Jean‐Louis Reymond, Florian Hollfelder, Tamis Darbre · 2016 · ChemBioChem
51. Nucleic acid delivery and nanoparticle design for COVID vaccines
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52. Nanoparticle-Based RNAi Therapeutics Targeting Cancer Stem Cells: Update and Prospective
    Yongquan Tang, Yan Chen, Zhe Zhang, Bo Tang, Zong‐Guang Zhou, Hai‐Ning Chen · 2021 · Pharmaceutics
53. Bioinspired Core–Shell Nanoparticles for Hydrophobic Drug Delivery
    Guangze Yang, Yun Liu, Haofei Wang, Russell J. Wilson, Yue Hui, Lei Yu, David Wibowo, Cheng Zhang, Andrew K. Whittaker, Anton P. J. Middelberg et al. · 2019 · Angewandte Chemie
54. Therapeutic potential of targeting galectins – A biomaterials-focused perspective
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55. Emerging concepts in designing next-generation multifunctional nanomedicine for cancer treatment
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56. Engineering polyphenol-based carriers for nucleic acid delivery
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57. Peptide- and Amine-Modified Glucan Particles for the Delivery of Therapeutic siRNA
    Jessica L. Cohen, Yuefei Shen, Myriam Aouadi, Pranitha Vangala, Michaela Tencerová, Shinya U. Amano, Sarah M. C. Nicoloro, Joseph C. Yawe, Michael Czech · 2016 · Molecular Pharmaceutics
58. Aerosol Delivery of siRNA to the Lungs. Part 2: Nanocarrier-based Delivery Systems
    Susanne R. Youngren-Ortiz, Nishant S. Gandhi, Laura España‐Serrano, Mahavir Bhupal Chougule · 2016 · KONA Powder and Particle Journal
59. Viral/Nonviral Chimeric Nanoparticles To Synergistically Suppress Leukemia Proliferation via Simultaneous Gene Transduction and Silencing
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60. In vitro 3D model and miRNA drug delivery to target calcific aortic valve disease
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61. Selenium‐Containing Nanocomplexes Achieve Dual Immune Checkpoint Blockade for NK Cell Reinvigoration
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62. LncOCMRL1 promotes oral squamous cell carcinoma growth and metastasis via the RRM2/EMT pathway
    Nan Lü, Qiming Jiang, Tianshu Xu, Qiyuan Gao, Yuepeng Wang, Zixian Huang, Zhiquan Huang, Xiaoding Xu · 2024 · Journal of Experimental & Clinical Cancer Research
63. Supramolecular Aggregate as a High-Efficiency Gene Carrier Mediated with Optimized Assembly Structure
    Yi Zhang, Junkun Duan, Lingguang Cai, Dong Ma, Wei Xue · 2016 · ACS Applied Materials & Interfaces
64. Hierarchical Assembly of siRNA with Tetraamino Fullerene in Physiological Conditions for Efficient Internalization into Cells and Knockdown
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65. Double Click-Functionalized siRNA Polyplexes for Gene Silencing in Epidermal Growth Factor Receptor-Positive Tumor Cells
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66. Applications of nanomaterials in COVID‐19 pandemic
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67. The effective function of circular RNA in colorectal cancer
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68. Erythrocyte membrane camouflaged siRNA/chemodrug nanoassemblies for cancer combination therapy
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69. In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy
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70. Recycling Gene Carrier with High Efficiency and Low Toxicity Mediated by L-Cystine-Bridged Bis(β-cyclodextrin)s
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71. Small Players Ruling the Hard Game: siRNA in Bone Regeneration
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72. Computational prediction of potential siRNA and human miRNA sequences to silence orf1ab associated genes for future therapeutics against SARS-CoV-2
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73. Receptor for advanced glycation end‐products: Biological significance and imaging applications
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74. M1-polarized macrophage-derived cellular nanovesicle-coated lipid nanoparticles for enhanced cancer treatment through hybridization of gene therapy and cancer immunotherapy
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75. Recent Progress in Nucleic Acid Pulmonary Delivery toward Overcoming Physiological Barriers and Improving Transfection Efficiency
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76. The Yin and Yang of nucleic acid-based therapy in the brain
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77. An artificial cationic oligosaccharide combined with phosphorothioate linkages strongly improves siRNA stability
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78. Delivery of siRNA to Endothelial Cells In Vivo Using Lysine/Histidine Oligopeptide-Modified Poly(β-amino ester) Nanoparticles
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79. A Review of pH‐Responsive Organic–Inorganic Hybrid Nanoparticles for RNAi‐Based Therapeutics
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80. Antitumor therapy for breast cancer: Focus on tumor‐associated macrophages and nanosized drug delivery systems
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81. Ionizable drug delivery systems for efficient and selective gene therapy
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82. Application of nanotechnology in the treatment of glomerulonephritis: current status and future perspectives
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83. SOCS3: A common target for neuronal protection and axon regeneration after spinal cord injury
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84. Cell Growth Inhibition Effect of DsiRNA Vectorised by Pectin-Coated Chitosan-Graphene Oxide Nanocomposites as Potential Therapy for Colon Cancer
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85. Multi‐Functional Peptide–MicroRNA Nanocomplex for Targeted MicroRNA Delivery and Function Imaging
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86. Polyester based nanovehicles for siRNA delivery
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87. Antibody‐drug therapeutic conjugates: Potential of antibody‐siRNAs in cancer therapy
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88. New Considerations in the Preparation of Nucleic Acid-Loaded Extracellular Vesicles
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89. Targeting ST8SIA6-AS1 counteracts KRASG12C inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling
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90. Targeted delivery of polo-like kinase 1 siRNA nanoparticles using an EGFR-PEG bispecific antibody inhibits proliferation of high-risk neuroblastoma.
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91. Advances in nucleic acid therapeutics: structures, delivery systems, and future perspectives in cancer treatment
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92. Lectin-Based Approaches to Analyze the Role of Glycans and Their Clinical Application in Disease
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93. Zwitterionic Polymer Lipid Nanoparticles Enabling Selective Organ Targeting Delivery of Small Interfering RNA for the Treatment of Hepatic and Pulmonary Inflammation
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94. Complexity in the therapeutic delivery of RNAi medicines: an analytical challenge
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95. Splicing factor mutations in the myelodysplastic syndromes: target genes and therapeutic approaches
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96. Dextran-Conjugated Caged siRNA Nanoparticles for Photochemical Regulation of RNAi-Induced Gene Silencing in Cells and Mice
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97. Are we creating a new phenotype? Physiological barriers and ethical considerations in the treatment of hereditary transthyretin-amyloidosis
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98. DNA Nanogel for Cancer Therapy
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99. RNA interference technology for anti-VEGF treatment
    Shun Chen, Jia Feng, Liuqing Ma, Zhenguo Liu, Weien Yuan · 2014 · Expert Opinion on Drug Delivery
100. Polyurea dendrimer for efficient cytosolic siRNA delivery
     Rita B. Restani, João Conde, Pedro Viana Baptista, Maria Teresa Cidade, Ana M. Bragança, Jorge Morgado, Ilídio Joaquim Correia, Ana Aguiar‐Ricardo, Vasco D. B. Bonifácio · 2014 · RSC Advances