Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

McGowan, Patrick O, Sasaki, Aya, D'Alessio, Ana C, Dymov, Sergiy, Labonté, Benoit, Szyf, Moshe, Turecki, Gustavo, Meaney, Michael J·2009·Nature Neuroscience
DOI 10.1038/nn.2270

Cited by (1,057)

Items 301–400 of 1,057

  1. DNA methylation: conducting the orchestra from exposure to phenotype?
    Fleur A. D. Leenen, Claude P. Muller, Jonathan D. Turner · 2016 · Clinical Epigenetics
  2. Child Maltreatment and Developmental Psychopathology: A Multilevel Perspective
    Dante Cicchetti, Sheree L. Toth · 2016 · Wiley eBooks
  3. Epigenetic mechanisms of major depression: Targeting neuronal plasticity
    Uchida, Shusaku, Yamagata, Hirotaka, Seki, Tomoe, Watanabe, Yoshifumi · 2018 · Psychiatry and Clinical Neurosciences
  4. Epigenetic programming by early‐life stress: Evidence from human populations
    Alexander M. Vaiserman · 2014 · Developmental Dynamics
  5. How Biology Became Social, and What it Means for Social Theory
    Maurizio Meloni · 2014 · The Sociological Review
  6. Developmental programming of early brain and behaviour development and mental health: a conceptual framework
    Bea R.H. Van den Bergh · 2011 · Developmental Medicine & Child Neurology
  7. Interpersonal Stress Regulation and the Development of Anxiety Disorders: An Attachment-Based Developmental Framework
    Tobias Nolte, Jo Guiney, Peter Fonagy, Linda C. Mayes, Patrick Luyten · 2011 · Frontiers in Behavioral Neuroscience
  8. Early life adversity shapes neural circuit function during sensitive postnatal developmental periods
    Malave, Lauren, van Dijk, Milenna T., Anacker, Christoph · 2022 · Translational Psychiatry
  9. Wheel running and environmental enrichment differentially modify exon‐specific BDNF expression in the hippocampus of wild‐type and pre‐motor symptomatic male and female Huntington's disease mice
    Michelle S. Zajac, Terence Y. Pang, Nicholas C. Wong, Blaise Weinrich, L Leang, Jeffrey Mark Craig, Richard Saffery, Anthony John Hannan · 2009 · Hippocampus
  10. Situating local biologies: Anthropological perspectives on environment/human entanglements
    Jörg Niewöhner, Margaret M. Lock · 2018 · BioSocieties
  11. Epigenetics and the Biological Basis of Gene × Environment Interactions
    Bagot, Rosemary C., Meaney, Michael J. · 2010 · Journal of the American Academy of Child & Adolescent Psychiatry
  12. DNA methylation of the serotonin transporter gene in peripheral cells and stress-related changes in hippocampal volume: a study in depressed patients and healthy controls
    Booij, Linda, Szyf, Moshe, Carballedo, Angela, Frey, Eva-Maria, Morris, Derek, Dymov, Sergiy, Vaisheva, Farida, Ly, Victoria, Fahey, Ciara, Meaney, James et al. · 2015 · PLOS ONE
  13. Impact of early adversity on glucocorticoid regulation and later mental disorders
    Strüber, Nicole, Strüber, Daniel, Roth, Gerhard · 2014 · Neuroscience & Biobehavioral Reviews
  14. Oxytocin receptor genetic and epigenetic variations: Association with child abuse and adult psychiatric symptoms
    Smearman, Erica L, Almli, Lynn M, Conneely, Karen N, Brody, Gene H, Sales, Jessica M, Bradley, Bekh, Ressler, Kerry J, Smith, Alicia K · 2016 · Child Development
  15. An epigenetic mechanism links socioeconomic status to changes in depression-related brain function in high-risk adolescents
    Johnna R. Swartz, Ahmad R. Hariri, Douglas E. Williamson · 2016 · Molecular Psychiatry
  16. The Involvement of Hypothalamus–Pituitary–Adrenal (HPA) Axis in Suicide Risk
    Isabella Berardelli, Gianluca Serafini, Natalia Cortese, Federica Fiaschè, Rory C. O’Connor, Maurizio Pompili · 2020 · Brain Sciences
  17. Epigenetics and the Transition from Acute to Chronic Pain
    Thomas Edward Buchheit, Thomas Van de Ven, Andrew Shaw · 2012 · Pain Medicine
  18. Epigenetic Inheritance of Disease and Disease Risk
    Johannes Bohacek, Isabelle M. Mansuy · 2012 · Neuropsychopharmacology
  19. Making room for oxytocin in understanding depression
    Robyn Jane McQuaid, Opal Arilla McInnis, Alfonso B. Abizaid, Hymie Anisman · 2014 · Neuroscience & Biobehavioral Reviews
  20. Glucocorticoid-Mediated Phenotypes in Vertebrates
    Michaela Hau, Stefania Casagrande, Jenny Q. Ouyang, Alexander T. Baugh · 2016 · Advances in the study of behavior
  21. Epigenetic modification of the glucocorticoid receptor gene is linked to traumatic memory and post-traumatic stress disorder risk in genocide survivors
    Vukojevic, V., Kolassa, I.-T., Fastenrath, M., Gschwind, L., Spalek, K., Milnik, A., Heck, A., Vogler, C., Wilker, S., Demougin, P. et al. · 2014 · Journal of Neuroscience
  22. Epigenetic signaling in psychiatric disorders: stress and depression
    Bagot, Rosemary C., Labonté, Benoit, Peña, Catherine J., Nestler, Eric J. · 2014 · Dialogues in Clinical Neuroscience
  23. Perinatal programming of adult hippocampal structure and function; emerging roles of stress, nutrition and epigenetics
    Paul John Lucassen, Eva F. G. Naninck, Johannes B. van Goudoever, Carlos Patricio Fitzsimons, Marian Joëls, Anikó Kőrösi · 2013 · Trends in Neurosciences
  24. A systematic review of childhood maltreatment and DNA methylation: candidate gene and epigenome-wide approaches
    Stephanie Hart Parade, Lindsay P. Huffhines, Teresa E. Daniels, Laura R. Stroud, Nicole R. Nugent, Audrey R. Tyrka · 2021 · Translational Psychiatry
  25. Analysis of DNA methylation in young people: limited evidence for an association between victimization stress and epigenetic variation in blood
    Marzi, Sarah J., Sugden, Karen, Arseneault, Louise, Belsky, Daniel W., Burrage, Joe, Corcoran, David L., Danese, Andrea, Fisher, Helen L., Hannon, Eilis, Moffitt, Terrie E. et al. · 2018 · American Journal of Psychiatry
  26. Genome-wide DNA methylation in neonates exposed to maternal depression, anxiety, or SSRI medication during pregnancy
    Amy L. Non, Alexandra M. Binder, Laura Diane Kubzansky, Karin B. Michels · 2014 · Epigenetics
  27. Biomarkers of PTSD: Neuropeptides and immune signaling
    Dewleen G. Baker, Caroline M. Nievergelt, Daniel T. O’Connor · 2011 · Neuropharmacology
  28. Glucocorticoid receptor gene (NR3C1) methylation following stressful events between birth and adolescence. The TRAILS study
    van der Knaap, L J, Riese, H, Hudziak, J J, Verbiest, M M P J, Verhulst, F C, Oldehinkel, A J, van Oort, F V A · 2014 · Translational Psychiatry
  29. Sex-Specific and Strain-Dependent Effects of Early Life Adversity on Behavioral and Epigenetic Outcomes
    Marija Kundaković, Sean C. Lim, Kathryn M. Gudsnuk, Frances A. Champagne · 2013 · Frontiers in Psychiatry
  30. Borderline personality disorder and childhood trauma: exploring the affected biological systems and mechanisms
    Nadia Cattane, Roberta Rossi, Mariangela Lanfredi, Annamaria Cattaneo · 2017 · BMC Psychiatry
  31. Childhood maltreatment and DNA methylation: A systematic review
    Charlotte A. M. Cecil, Yuning Zhang, Tobias Nolte · 2020 · Neuroscience & Biobehavioral Reviews
  32. Epigenetic mechanisms in schizophrenia
    Tania L. Roth, Farah D. Lubin, Monsheel Sodhi, Joel E. Kleinman · 2009 · Biochimica et Biophysica Acta (BBA) - General Subjects
  33. Effects of prenatal and postnatal depression, and maternal stroking, at the glucocorticoid receptor gene
    Chris Murgatroyd, John Peter Quinn, Helen M. Sharp, Andrew R. Pickles, J Hill · 2015 · Translational Psychiatry
  34. Neighborhood characteristics influence DNA methylation of genes involved in stress response and inflammation: The Multi-Ethnic Study of Atherosclerosis
    Jennifer A. Smith, Wei Zhao, Xu Wang, Scott M. Ratliff, Bhramar Mukherjee, Sharon L. R. Kardia, Yongmei Liu, Ana Victoria Diez Roux, Belinda L. Needham · 2017 · Epigenetics
  35. Developmental origins of the human hypothalamic-pituitary-adrenal axis
    Mariann A. Howland, Curt A. Sandman, Laura M. Glynn · 2017 · Expert Review of Endocrinology & Metabolism
  36. Epigenetic modulation of glucocorticoid receptors in posttraumatic stress disorder
    Labonté, B, Azoulay, N, Yerko, V, Turecki, G, Brunet, A · 2014 · Translational Psychiatry
  37. Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior
    Alec Roy, Colin A. Hodgkinson, Vincenzo De Luca, David A Goldman, Mary‐Anne Enoch · 2011 · Journal of Psychiatric Research
  38. Effects of early life stress on amygdala and striatal development
    Dominic S. Fareri, Nim Tottenham · 2016 · Developmental Cognitive Neuroscience
  39. Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions
    Bojan Mirkovic, Claudine Laurent‐Levinson, Marc-Antoine Podlipski, Thierry Frébourg, David Cohen, Priscille Gérardin · 2016 · Frontiers in Psychiatry
  40. In my end is my beginning: developmental trajectories of adverse childhood experiences to late-life suicide
    Natalie Sachs‐Ericsson, Nicole Collins Rushing, Ian H. Stanley, Julia Sheffler · 2015 · Aging & Mental Health
  41. Epigenetic alterations in depression and antidepressant treatment
    Menke, Andreas, Binder, Elisabeth B. · 2014 · Dialogues in Clinical Neuroscience
  42. Pathogenesis and pathophysiology of functional (psychogenic) movement disorders
    Baizabal-Carvallo, José Fidel, Hallett, Mark, Jankovic, Joseph · 2019 · Neurobiology of Disease
  43. Birth practices: Maternal‐neonate separation as a source of toxic stress
    Nils Bergman · 2019 · Birth Defects Research
  44. Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering
    Margarethe M Bosma-den Boer, Marie-Louise van Wetten, Leo Pruimboom · 2012 · Nutrition & Metabolism
  45. Home Visiting and the Biology of Toxic Stress: Opportunities to Address Early Childhood Adversity
    Andrew S. Garner · 2013 · PEDIATRICS
  46. Epigenetic alterations following early postnatal stress: a review on novel aetiological mechanisms of common psychiatric disorders
    Magdalene C. Jawahar, Chris Murgatroyd, Emma L. Harrison, Bernhard Theodor Baune · 2015 · Clinical Epigenetics
  47. Epigenetic Signaling in Psychiatric Disorders
    Peña, Catherine J., Bagot, Rosemary C., Labonté, Benoit, Nestler, Eric J. · 2014 · Journal of Molecular Biology
  48. Birthweight is associated with DNA promoter methylation of the glucocorticoid receptor in human placenta
    Amanda C. Filiberto, Matthew Alan Maccani, Devin C. Koestler, Charlotte S. Wilhelm-Benartzi, Michele Avissar-Whiting, Carolyn E. Banister, Luc A. Gagne, Carmen J. Marsit · 2011 · Epigenetics
  49. Beyond the ACE score: Examining relationships between timing of developmental adversity, relational health and developmental outcomes in children
    Erin P. Hambrick, Thomas W. Brawner, Bruce D. Perry, Kristie A. Brandt, Christine Hofmeister, Jen O. Collins · 2018 · Archives of Psychiatric Nursing
  50. Epigenetic programming by stress and glucocorticoids along the human lifespan
    Zannas, A S, Chrousos, G P · 2017 · Molecular Psychiatry
  51. Maternal separation with early weaning: A novel mouse model of early life neglect
    George, Elizabeth D, Bordner, Kelly A, Elwafi, Hani M, Simen, Arthur A · 2010 · BMC Neuroscience
  52. Psychiatric resilience: longitudinal twin study
    Ananda B. Amstadter, John Myers, Kenneth S. Kendler · 2014 · The British Journal of Psychiatry
  53. Effects of Adverse Early‐Life Events on Aggression and Anti‐Social Behaviours in Animals and Humans
    József Haller, Gordon T. Harold, Carmen Sandi, Inga D. Neumann · 2014 · Journal of Neuroendocrinology
  54. Neuropathology of suicide: Recent findings and future directions
    Lutz, P-E, Mechawar, N, Turecki, G · 2017 · Molecular Psychiatry
  55. The early life social environment and DNA methylation: DNA methylation mediating the long-term impact of social environments early in life
    Szyf, Moshe · 2011 · Epigenetics
  56. Parenting begets parenting: A neurobiological perspective on early adversity and the transmission of parenting styles across generations
    Lomanowska, A.M., Boivin, M., Hertzman, C., Fleming, A.S. · 2017 · Neuroscience
  57. Gene–Environment Interaction in Major Depression: Focus on Experience-Dependent Biological Systems
    Nicola Lopizzo, Luisella Bocchio‐Chiavetto, Nadia Cattane, Giona Plazzotta, Frank I. Tarazi, Carmine Maria Pariante, Marco Andrea Riva, Annamaria Cattaneo · 2015 · Frontiers in Psychiatry
  58. Epigenetic malprogramming of the insulin receptor promoter due to developmental overfeeding
    Andreas Plagemann, Katharina Roepke, Thomas Harder, Matthias Brunn, Anja Harder, Manon Josephine Wittrock-Staar, Thomas Ziska, Karen Schellong, Elke Rodekamp, Kerstin Melchior et al. · 2010 · Journal of Perinatal Medicine
  59. The social brain meets the reactive genome: neuroscience, epigenetics and the new social biology
    Maurizio Meloni · 2014 · Frontiers in Human Neuroscience
  60. Suicide neurobiology
    Carl Ernst, Naguib Mechawar, Gustavo Turecki · 2009 · Progress in Neurobiology
  61. Prenatal synthetic glucocorticoid treatment changes DNA methylation states in male organ systems: multigenerational effects
    Crudo, Ariann, Petropoulos, Sophie, Moisiadis, Vasilis G., Iqbal, Majid, Kostaki, Alisa, Machnes, Ziv, Szyf, Moshe, Matthews, Stephen G. · 2012 · Endocrinology
  62. Epigenetic regulation of serotonin transporter expression and behavior in infant rhesus macaques
    Kinnally, E. L., Capitanio, J. P., Leibel, R., Deng, L., LeDuc, C., Haghighi, F., Mann, J. J. · 2010 · Genes, Brain and Behavior
  63. The CREB1-BDNF-NTRK2 Pathway in Depression: Multiple Gene-Cognition-Environment Interactions
    Gabriella Juhász, Jason S. Dunham, Shane McKie, Emma Thomas, Darragh Downey, Diana S. Chase, Kathryn Lloyd-Williams, Zoltan G. Toth, Hazel Platt, Krisztina Mekli et al. · 2011 · Biological Psychiatry
  64. The applied implications of epigenetics in anxiety, affective and stress-related disorders - A review and synthesis on psychosocial stress, psychotherapy and prevention
    Schiele, Miriam A., Gottschalk, Michael G., Domschke, Katharina · 2020 · Clinical Psychology Review
  65. Translating basic research knowledge on the biological embedding of early-life stress into novel approaches for the developmental programming of lifelong health
    Heim, Christine M., Entringer, Sonja, Buss, Claudia · 2019 · Psychoneuroendocrinology
  66. Stress and the psyche–brain–immune network in psychiatric diseases based on psychoneuroendocrineimmunology: a concise review
    Anna Giulia Bottaccioli, Francesco Bottaccioli, Andrea Minelli · 2018 · Annals of the New York Academy of Sciences
  67. Population neuroscience: Why and how
    Tomáš Paus · 2010 · Human Brain Mapping
  68. Biological pathways for historical trauma to affect health: A conceptual model focusing on epigenetic modifications
    Andie Conching, Zaneta M. Thayer · 2019 · Social Science & Medicine
  69. Suicidal behaviour and memory: A systematic review and meta-analysis
    Richard-Devantoy, Stephane, Berlim, Marcelo T., Jollant, Fabrice · 2015 · The World Journal of Biological Psychiatry
  70. Heritability of children's prosocial behavior and differential susceptibility to parenting by variation in the dopamine receptor D4 gene
    Knafo, Ariel, Israel, Salomon, Ebstein, Richard P. · 2011 · Development and Psychopathology
  71. Genetics of anxiety disorders: Genetic epidemiological and molecular studies in humans
    Mihoko Shimada‐Sugimoto, Takeshi Otowa, John M. Hettema · 2015 · Psychiatry and Clinical Neurosciences
  72. The Neurobiology and Psychology of Pedophilia: Recent Advances and Challenges
    Gilian Tenbergen, Matthias Wittfoth, Helge Frieling, Jorge Ponseti, Martin Walter, Henrik Walter, Klaus Michael Beier, Boris Schiffer, Tillmann H. C. Krüger · 2015 · Frontiers in Human Neuroscience
  73. Depression as a risk factor for Alzheimer’s disease: Genes, steroids, cytokines and neurogenesis – What do we need to know?
    Herbert, Joe, Lucassen, Paul J. · 2016 · Frontiers in Neuroendocrinology
  74. Developmental programming and epigenetics
    Anne Gabory, Linda Attig, Claudine Junien · 2011 · American Journal of Clinical Nutrition
  75. Consequences of adolescent use of alcohol and other drugs: Studies using rodent models
    LINDA PATIA SPEAR · 2016 · Neuroscience & Biobehavioral Reviews
  76. Early Life Stress, Mood, and Anxiety Disorders
    Shariful A. Syed, Charles B. Nemeroff · 2017 · Chronic Stress
  77. Neuroinflammation in suicide: Toward a comprehensive model
    Courtet, Philippe, Giner, Lucas, Seneque, Maude, Guillaume, Sebastien, Olie, Emilie, Ducasse, Deborah · 2016 · The World Journal of Biological Psychiatry
  78. Inflammation and neuronal plasticity: a link between childhood trauma and depression pathogenesis
    Cattaneo, Annamaria, Macchi, Flavia, Plazzotta, Giona, Veronica, Begni, Bocchio-Chiavetto, Luisella, Riva, Marco Andrea, Pariante, Carmine Maria · 2015 · Frontiers in Cellular Neuroscience
  79. Timescales of Human Adaptation: The Role of Epigenetic Processes
    Christopher W. Kuzawa, Zaneta M. Thayer · 2011 · Epigenomics
  80. Individual differences in stress susceptibility and stress inhibitory mechanisms
    Karl Ebner, Nicolas Singewald · 2016 · Current Opinion in Behavioral Sciences
  81. Medical comorbidity in bipolar disorder: The link with metabolic-inflammatory systems
    Ana SayuriYamagata, Elisa Macedo Brietzke, Joshua Daniel Rosenblat, Ron Kakar, Roger S. McIntyre · 2017 · Journal of Affective Disorders
  82. Child Maltreatment and Long-Term Physical and Mental Health Outcomes: An Exploration of Biopsychosocial Determinants and Implications for Prevention
    Divya Mehta, Adrian B. Kelly, Kristin R. Laurens, Divna M. Haslam, Kate E Williams, Kerryann Walsh, Philip Baker, Hannah Elizabeth Carter, Nigar Gohar Khawaja, Oksana Zelenko et al. · 2021 · Child Psychiatry & Human Development
  83. Memory, autonoetic consciousness, and the self
    Hans Joachim Markowitsch, Angelica Staniloiu · 2010 · Consciousness and Cognition
  84. Development and the epigenome: the ‘synapse’ of gene–environment interplay
    William Thomas Boyce, Michael Steffen Kobor · 2014 · Developmental Science
  85. Preventive Interventions for ADHD: A Neurodevelopmental Perspective
    Jeffrey M. Halperin, Anne‐Claude Bedard, Jocelyn T. Curchack · 2012 · Neurotherapeutics
  86. Behavioral, emotional and neurobiological determinants of coronary heart disease risk in women
    Viola Vaccarino, J. Douglas Bremner · 2016 · Neuroscience & Biobehavioral Reviews
  87. Epigenetics and parental effects
    Laurent Kappeler, Michael Joseph Meaney · 2010 · BioEssays
  88. The Biological Underpinnings of Peer Victimization: Understanding Why and How the Effects of Bullying Can Last a Lifetime
    Tracy Vaillancourt, Shelley Claire Hymel, Patricia McDougall · 2013 · Theory Into Practice
  89. Epigenetic effects of stress and corticosteroids in the brain
    Richard G Hunter · 2012 · Frontiers in Cellular Neuroscience
  90. Early life adversity, genomic plasticity, and psychopathology
    Gustavo Turecki, Vanessa Ota, Sintia Iole Belangero, Andrea Parolin Jackowski, Joan Kaufman · 2014 · The Lancet Psychiatry
  91. Antidepressant‐like effect induced by systemic and intra‐hippocampal administration of DNA methylation inhibitors
    Sales, Amanda J, Biojone, Caroline, Terceti, Mateus S, Guimarães, Francisco S, Gomes, Marcus VM, Joca, Sâmia RL · 2011 · British Journal of Pharmacology
  92. Epigenetics of Stress, Addiction, and Resilience: Therapeutic Implications
    Jean Lud Cadet · 2014 · Molecular Neurobiology
  93. Peripheral Nerve Injury Is Associated with Chronic, Reversible Changes in Global DNA Methylation in the Mouse Prefrontal Cortex
    Maral Tajerian, Sebastian Gaston Alvarado, Magali Millecamps, Pascal Vachon, Cecilia Crosby, Mary Catherine Bushnell, Moshe Szyf A, Laura S. Stone · 2013 · PLoS ONE
  94. A meta-analytical evaluation of the dual-hormone hypothesis: Does cortisol moderate the relationship between testosterone and status, dominance, risk taking, aggression, and psychopathy?
    Tycho J. Dekkers, Joost A. Agelink van Rentergem, Bren Meijer, Arne Popma, Eline Wagemaker, Hilde M. Huizenga · 2018 · Neuroscience & Biobehavioral Reviews
  95. DNA methylation differences at the glucocorticoid receptor gene in depression are related to functional alterations in hypothalamic-pituitary-adrenal axis activity and to early life emotional abuse
    Farrell, Chloё, Doolin, Kelly, O’ Leary, Niamh, Jairaj, Chaitra, Roddy, Darren, Tozzi, Leonardo, Morris, Derek, Harkin, Andrew, Frodl, Thomas, Nemoda, Zsófia et al. · 2018 · Psychiatry Research
  96. DNA methylation, early life environment, and health outcomes
    Mitchell, Colter, Schneper, Lisa M., Notterman, Daniel A. · 2016 · Pediatric Research
  97. Transcriptional control of the glucocorticoid receptor: CpG islands, epigenetics and more
    Jonathan D. Turner, Simone R. Alt, Lei Cao, Sara Vernocchi, Slavena T. Trifonova, Nadia Battello, Claude P. Muller · 2010 · Biochemical Pharmacology
  98. The neurobiological correlates of childhood adversity and implications for treatment
    Tyrka, A. R., Burgers, D. E., Philip, N. S., Price, L. H., Carpenter, L. L. · 2013 · Acta Psychiatrica Scandinavica
  99. Blunted endocrine and cardiovascular reactivity in young healthy women reporting a history of childhood adversity
    Voellmin, Annette, Winzeler, Katja, Hug, Evelin, Wilhelm, Frank H., Schaefer, Valérie, Gaab, Jens, La Marca, Roberto, Pruessner, Jens C., Bader, Klaus · 2015 · Psychoneuroendocrinology
  100. Inflammatory biomarker profiles of mental disorders and their relation to clinical, social and lifestyle factors
    Baumeister, David, Russell, Alice, Pariante, Carmine M., Mondelli, Valeria · 2014 · Social Psychiatry and Psychiatric Epidemiology