Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
McGowan, Patrick O, Sasaki, Aya, D'Alessio, Ana C, Dymov, Sergiy, Labonté, Benoit, Szyf, Moshe, Turecki, Gustavo, Meaney, Michael J·2009·Nature Neuroscience
DOI 10.1038/nn.2270
Cited by (1,057)
Items 501–600 of 1,057
- Development of individual differences in stress responsiveness: an overview of factors mediating the outcome of early life experiencesSanne E.F. Claessens, Nikolaos P. Daskalakis, Rixt van der Veen, Melly Silvana Oitzl, E. R. de Kloet, Danielle L. Champagne · 2010 · Psychopharmacology
- Gestational stress induces depressive-like and anxiety-like phenotypes through epigenetic regulation of BDNF expression in offspring hippocampusZheng, Yu, Fan, Weidong, Zhang, Xianquan, Dong, Erbo · 2016 · Epigenetics
- The international society for developmental psychobiology Sackler symposium: early adversity and the maturation of emotion circuits-a cross-species analysisCallaghan, Bridget L., Sullivan, Regina M., Howell, Brittany, Tottenham, Nim · 2014 · Developmental Psychobiology
- Parenting and Beyond: Common Neurocircuits Underlying Parental and Altruistic CaregivingJames E. Swain, Sara Konrath, Stephanie L. Brown, Eric D. Finegood, L. Akce, Carolyn Joy Dayton, Shao-Hsuan Shaun Ho · 2012 · Parenting
- DNA methylation-based variation between human populationsFarzeen Kader, Meenu Ghai · 2016 · Molecular Genetics and Genomics
- Histone Deacetylases and Mood Disorders: Epigenetic Programming in Gene‐Environment InteractionsRodrigo Machado‐Vieira, Lobna A. Ibrahim, Carlos A. Zarate · 2010 · CNS Neuroscience & Therapeutics
- Developmental origins of cardiovascular disease: Impact of early life stress in humans and rodentsMurphy, M.O., Cohn, D.M., Loria, A.S. · 2017 · Neuroscience & Biobehavioral Reviews
- Shaping adult phenotypes through early life environmentsIan C.G. Weaver · 2009 · Birth Defects Research Part C Embryo Today Reviews
- Childhood Maltreatment and Migraine (Part III). Association With Comorbid Pain ConditionsGretchen E. Tietjen, Jan Lewis Brandes, Barbara Lee Peterlin, Arnolda Eloff, Rima M. Dafer, Michael R. Stein, Ellen D. Drexler, Vincent T. Martin, Susan L. Hutchinson, Sheena K. Aurora et al. · 2009 · Headache The Journal of Head and Face Pain
- Methylation at the CpG island shore region upregulates Nr3c1 promoter activity after early-life stressYvonne Bockmühl, Alexandre V. Patchev, Arleta Madejska, Anke Hoffmann, João Carlos Sousa, Nuno Sousa, Florian Holsboer, Osborne F. X. Almeida, Dietmar Spengler · 2015 · Epigenetics
- Neurotrophic-priming of glucocorticoid receptor signaling is essential for neuronal plasticity to stress and antidepressant treatmentMargarita Arango-Lievano, W. Marcus Lambert, Kevin G. Bath, Michael J. Garabedian, Moses V. Chao, Freddy D. Jeanneteau · 2015 · Proceedings of the National Academy of Sciences
- Epigenetic Programming by Maternal Behavior in the Human InfantBarry M. Lester, Elisabeth D. Conradt, Linda L. LaGasse, Edward Z. Tronick, James F. Padbury, Carmen J. Marsit · 2018 · PEDIATRICS
- How adversity gets under the skinHyman, Steven E · 2009 · Nature Neuroscience
- Chronic stress and
<scp>A</scp>
lzheimer's disease: the interplay between the hypothalamic–pituitary–adrenal axis, genetics and microgliaMilligan Armstrong, Ayeisha, Porter, Tenielle, Quek, Hazel, White, Anthony, Haynes, John, Jackaman, Connie, Villemagne, Victor, Munyard, Kylie, Laws, Simon M., Verdile, Giuseppe et al. · 2021 · Biological Reviews
- Resilience Is Associated With Larger Dentate Gyrus, While Suicide Decedents With Major Depressive Disorder Have Fewer Granule NeuronsBoldrini, Maura, Galfalvy, Hanga, Dwork, Andrew J., Rosoklija, Gorazd B., Trencevska-Ivanovska, Iskra, Pavlovski, Goran, Hen, René, Arango, Victoria, Mann, J. John · 2019 · Biological Psychiatry
- Genetic and epigenetic variation of the glucocorticoid receptor (NR3C1) in placenta and infant neurobehaviorCailey Bromer, Carmen J. Marsit, David A. Armstrong, James F. Padbury, Barry M. Lester · 2012 · Developmental Psychobiology
- Coping in old age with extreme childhood trauma: Aging Holocaust survivors and their offspring facing new challengesAyala Fridman, Marian J. Bakermans‐Kranenburg, Abraham Sagi‐Schwartz, Marinus H. van IJzendoorn · 2010 · Aging & Mental Health
- Genome-wide conserved consensus transcription factor binding motifs are hyper-methylatedMun‐Kit Choy, Mehregan Movassagh, Hock Guan Goh, Martin R. Bennett, Thomas A. Down, Roger Foo · 2010 · BMC Genomics
- The urban environment and mental disordersSandro Galea, Monica Uddin, Karestan Chase Koenen · 2011 · Epigenetics
- Looking beyond the DNA sequence: the relevance of DNA methylation processes for the stress–diathesis model of depressionLinda Booij, Dongsha Wang, Mélissa L. Lévesque, Richard Ernest Tremblay, Moshe Szyf · 2013 · Philosophical Transactions of the Royal Society B Biological Sciences
- Brain-derived neurotrophic factor and suicide pathogenesisYogesh Dwivedi · 2010 · Annals of Medicine
- Borderline personality disorder and childhood maltreatment: A genome-wide methylation analysisPrados, J., Stenz, L., Courtet, P., Prada, P., Nicastro, R., Adouan, W., Guillaume, S., Olié, E., Aubry, J.‐M., Dayer, A. et al. · 2015 · Genes, Brain and Behavior
- Early Onset Pre-Eclampsia Is Associated with Altered DNA Methylation of Cortisol-Signalling and Steroidogenic Genes in the PlacentaKirsten Hogg, John D. Blair, Deborah E. McFadden, Peter von Dadelszen, Wendy P. Robinson · 2013 · PLoS ONE
- Does intranasal oxytocin promote prosocial behavior to an excluded fellow player? A randomized-controlled trial with CyberballMadelon M. E. Riem, Marian J. Bakermans‐Kranenburg, Renske Huffmeijer, Marinus H. van IJzendoorn · 2013 · Psychoneuroendocrinology
- The role of stress in drug addiction. An integrative reviewPablo Ruisoto, Israel Contador · 2019 · Physiology & Behavior
- HPA Axis Alterations in Mental Disorders: Impact on Memory and its Relevance for Therapeutic InterventionsKatja Wingenfeld, Oliver Tobias Wolf · 2010 · CNS Neuroscience & Therapeutics
- Perinatal stress and early life programming of lung structure and functionRosalind J. Wright · 2010 · Biological Psychology
- The Molecular Stress ResponseErin Faught, Neel Aluru, Mathilakath M. Vijayan · 2016 · Fish physiology
- Oxytocin pathways in the intergenerational transmission of maternal early life stressPhilipp Töpfer, Christine C. Heim, Sonja Entringer, Elisabeth B. Binder, Pathik D. Wadhwa, Claudia Buß · 2016 · Neuroscience & Biobehavioral Reviews
- Environmental Stress Affects DNA Methylation of a CpG Rich Promoter Region of Serotonin Transporter Gene in a Nurse CohortJ. Alasaari, Markus Lagus, Hanna Maria Ollila, Auli Toivola, Mika Kivimaki B, Jussi Vahtera, Erkki Kronholm, Mikko Härmä, Sampsa Puttonen, Tiina Paunio · 2012 · PLoS ONE
- Traumatic stress and human DNA methylation: A critical reviewVinkers, Christiaan H, Kalafateli, Aimilia Lydia, Rutten, Bart PF, Kas, Martien J, Kaminsky, Zachary, Turner, Jonathan D, Boks, Marco PM · 2015 · Epigenomics
- Psychological Stress, Intestinal Barrier Dysfunctions, and Autoimmune Disorders: An OverviewHanna Ilchmann-Diounou, Sandrine Ménard · 2020 · Frontiers in Immunology
- Gene—Environment Interactions in Major Depressive DisorderTorsten Klengel, Elisabeth B. Binder · 2013 · The Canadian Journal of Psychiatry
- Neuroepigenetics of stressBrian B. Griffiths, Richard G Hunter · 2014 · Neuroscience
- Parental psychological distress during pregnancy and wheezing in preschool children: The Generation R StudyMònica Guxens, Agnes M.M. Sonnenschein–van der Voort, Henning W. Tiemeier, Albert Hofman D, Jordi Sunyer, Johan C. de Jongste, Vincent W. V. Jaddoe, Liesbeth Duijts · 2013 · Journal of Allergy and Clinical Immunology
- Methylation of the Glucocorticoid Receptor Gene Promoter in Preschoolers: Links With Internalizing Behavior ProblemsStephanie Hart Parade, Kathryn K. Ridout, Ronald Seifer, David A Armstrong, Carmen J. Marsit, Melissa A. McWilliams, Audrey R. Tyrka · 2016 · Child Development
- Early Adversity and Developmental Outcomes: Interaction Between Genetics, Epigenetics, and Social Experiences Across the Life SpanChampagne, Frances A. · 2010 · Perspectives on Psychological Science
- Maternal depression is associated with DNA methylation changes in cord blood T lymphocytes and adult hippocampiZsófia Nemoda, Renaud Massart, Matthew J Suderman, Michael T. Hallett, T. Li, Michelle L. Coote, Neal A. L. Cody, Zhong Sheng Sun, Cláudio N. Soares, Gustavo Turecki et al. · 2015 · Translational Psychiatry
- Neonatal pain and reduced maternal care: Early-life stressors interacting to impact brain and behavioral developmentSean M. Mooney‐Leber, Susanne Brummelte · 2016 · Neuroscience
- Early life adversity is associated with brain changes in subjects at family risk for depressionCarballedo, Angela, Lisiecka, Danutia, Fagan, Andrew, Saleh, Karim, Ferguson, Yolande, Connolly, Gerard, Meaney, James, Frodl, Thomas · 2012 · The World Journal of Biological Psychiatry
- The Next Generation of Psychological Autopsy Studies: Part I. Interview ContentConner, Kenneth R., Beautrais, Annette L., Brent, David A., Conwell, Yeates, Phillips, Michael R., Schneider, Barbara · 2011 · Suicide and Life-Threatening Behavior
- DNA demethylation and invasive cancer: implications for therapeuticsDavid Cheishvili, Lisa Boureau, Moshe Szyf · 2014 · British Journal of Pharmacology
- Microtrial Methods for Translating Gene-environment Dynamics into Preventive InterventionsGeorge W. Howe, Steven R. H. Beach, Gene H. Brody · 2010 · Prevention Science
- Neurosteroids and GABAA Receptor Interactions: A Focus on StressBenjamin G. Gunn, Adam R. Brown, Jeremy J. Lambert, Delia Belelli · 2011 · Frontiers in Neuroscience
- Childhood trauma and suicide risk in a sample of young individuals aged 14–35 years in southern BrazilLuana Porto Barbosa, Luciana de Ávila Quevedo, Giovanna Del Grande da Silva, Karen Jansen, Ricardo Tavares Pinheiro, Jerônimo Costa Branco, Diogo Rizzato Lara, Jean Pierre Oses, Ricardo Azevedo da Silva · 2014 · Child Abuse & Neglect
- Site-specific methylation changes in the glucocorticoid receptor exon 1F promoter in relation to life adversity: Systematic review of contributing factorsDaskalakis, Nikolaos P., Yehuda, Rachel · 2014 · Frontiers in Neuroscience
- Future Directions in Vulnerability to Depression Among Youth: Integrating Risk Factors and Processes Across Multiple Levels of AnalysisBenjamin L. Hankin · 2012 · Journal of Clinical Child & Adolescent Psychology
- Twin studies of posttraumatic stress disorder: Differentiating vulnerability factors from sequelaeWilliam S. Kremen, Karestan Chase Koenen, Niloofar Afari, Michael J. Lyons · 2011 · Neuropharmacology
- CDKL5 is a brain MeCP2 target gene regulated by DNA methylationDelphine Carouge, Lionel Host, Dominique Aunis, Jean Zwiller, Patrick Anglard · 2010 · Neurobiology of Disease
- Individual vulnerability to addictionJoel David Swendsen, Michel Le Moal · 2011 · Annals of the New York Academy of Sciences
- Developmental plasticityAmanda J. Lea, Jenny Tung, Elizabeth A. Archie, Susan C. Alberts · 2017 · Evolution Medicine and Public Health
- Hpa axis related genes and response to psychological therapies: Genetics and epigeneticsRoberts, Susanna, Keers, Robert, Lester, Kathryn J, Coleman, Jonathan R. I., Breen, Gerome, Arendt, Kristian, Blatter‐Meunier, Judith, Cooper, Peter, Creswell, Cathy, Fjermestad, Krister et al. · 2015 · Depression and Anxiety
- Contrasting effects of acute and chronic stress on the transcriptome, epigenome, and immune response of Atlantic salmonTamsyn M. Uren Webster, Deiene Rodríguez‐Barreto, Samuel Martín, Cock van Oosterhout, Pablo Orozco‐terWengel, Jo Cable, Alastair Hamilton, Carlos García de Leániz, Sofía Consuegra · 2018 · Epigenetics
- Intergenerational transmission of depression: clinical observations and molecular mechanismsKristi M. Sawyer, Patricia A. Zunszain, Paola Dazzan, Carmine Maria Pariante · 2018 · Molecular Psychiatry
- The neurobiology of depression—revisiting the serotonin hypothesis. II. Genetic, epigenetic and clinical studiesPaul R. Albert, Chawki Benkelfat · 2013 · Philosophical Transactions of the Royal Society B Biological Sciences
- Stress, cortisol and suicide risk2020 · International Review of Neurobiology
- Anxiogenic effects of developmental bisphenol A exposure are associated with gene expression changes in the juvenile rat amygdala and mitigated by soyPatisaul, Heather B., Sullivan, Alana W., Radford, Meghan E., Walker, Deena M., Adewale, Heather B., Winnik, Bozena, Coughlin, Janis L., Buckley, Brian, Gore, Andrea C. · 2012 · PLoS ONE
- DNA methylation profiles at birth and child ADHD symptoms.N. V. van Mil, R. Steegers-Theunissen, M. Bouwland-Both, M. Verbiest, J. Rijlaarsdam, A. Hofman, E. Steegers, B. Heijmans, V. Jaddoe, F. Verhulst et al. · 2014 · Journal of Psychiatric Research
- The dynamics of the stress neuromatrixNuno Sousa · 2016 · Molecular Psychiatry
- Epigenetics in Personality Disorders: Today's InsightsDorothee Maria Gescher, Kai G. Kahl, Thomas Hillemacher, Helge Frieling, Jens Kuhn, Thomas Frodl · 2018 · Frontiers in Psychiatry
- The impact of poverty on the development of brain networksSebastián Javier Lipina, Michael I. Posner · 2012 · Frontiers in Human Neuroscience
- Association of Intrauterine and Early-Life Exposures with Diagnosis of Uterine Leiomyomata by 35 Years of Age in the Sister StudyAimee A. D’Aloisio, Donna D. Baird, Lisa A. DeRoo, Dale P. Sandler · 2009 · Environmental Health Perspectives
- Glucocorticoid receptor DNA methylation, childhood maltreatment and major depressionBustamante, Angela C., Aiello, Allison E., Galea, Sandro, Ratanatharathorn, Andrew, Noronha, Carol, Wildman, Derek E., Uddin, Monica · 2016 · Journal of Affective Disorders
- The interface of stress and the HPA axis in behavioural phenotypes of mental illnessBaumeister, David, Lightman, Stafford L., Pariante, Carmine M. · 2014 · Current topics in behavioral neurosciences
- Neurobiology of emotional traumaOrestis Giotakos · 2020 · Psychiatriki
- Glucocorticoids, their uses, sexual dimorphisms, and diseases: new concepts, mechanisms, and discoveriesGenesee J. Martinez, Malik Appleton, Zachary A. Kipp, Analia Silvina Loria, Booki Min, Terry D. Hinds · 2023 · Physiological Reviews
- Glucocorticoid Sensitivity in Mood DisordersAnnet T. Spijker, Elisabeth F. C. van Rossum · 2011 · Neuroendocrinology
- Long-term effects of early life stress exposure: Role of epigenetic mechanismsDafne Magalı́ Silberman, Gabriela B. Acosta, María A. Zorrilla Zubilete · 2016 · Pharmacological Research
- Epigenetic mechanisms in schizophreniaKimberly R. Shorter, Brooke H. Miller · 2015 · Progress in Biophysics and Molecular Biology
- An epigenome-wide DNA methylation study of PTSD and depression in World Trade Center respondersKuan, P-F, Waszczuk, M A, Kotov, R, Marsit, C J, Guffanti, G, Gonzalez, A, Yang, X, Koenen, K, Bromet, E, Luft, B J · 2017 · Translational Psychiatry
- How Stress Gets Under the Skin: Early Life Adversity and Glucocorticoid Receptor Epigenetic RegulationPatrick Z. Liu, Robin Nusslock · 2017 · Current Genomics
- Depressed suicide attempters have smaller hippocampus than depressed patients without suicide attemptsColle, Romain, Chupin, Marie, Cury, Claire, Vandendrie, Christophe, Gressier, Florence, Hardy, Patrick, Falissard, Bruno, Colliot, Olivier, Ducreux, Denis, Corruble, Emmanuelle · 2015 · Journal of Psychiatric Research
- Programming of stress-related behavior and epigenetic neural gene regulation in mice offspring through maternal exposure to predator odorSt-Cyr, Sophie, McGowan, Patrick O. · 2015 · Frontiers in Behavioral Neuroscience
- Atypical Lateralization in Neurodevelopmental and Psychiatric Disorders: What Is the Role of Stress?Berretz, Gesa, Wolf, Oliver T., Güntürkün, Onur, Ocklenburg, Sebastian · 2020 · Cortex
- Neuroimmune mechanisms of stress: sex differences, developmental plasticity, and implications for pharmacotherapy of stress-related diseaseTerrence Deak, Matt Quinn, John Anthony Cidlowski, Nicole C. Victoria, Anne Z. Murphy, John F. Sheridan · 2015 · Stress
- Understanding risk for psychopathology through imaging gene–environment interactionsLuke Williamson Hyde, Ryan Bogdan, Ahmad R. Hariri · 2011 · Trends in Cognitive Sciences
- Associations among oxytocin receptor gene (OXTR) DNA methylation in adulthood, exposure to early life adversity, and childhood trajectories of anxiousnessJean-Philippe Gouin, Q. Q. Zhou, Linda Booij, Michel Boivin, Sylvana M. Côté, Martine Hébert, Isabelle Ouellet‐Morin, Moshe Szyf A, Richard Ernest Tremblay, Gustavo Turecki et al. · 2017 · Scientific Reports
- SKA2 methylation is associated with decreased prefrontal cortical thickness and greater PTSD severity among trauma-exposed veteransNaomi Sadeh, Jeffrey M. Spielberg, Mark W. Logue, Erika J. Wolf, Alicia K. Smith, Joanna Lusk, Jasmeet Pannu Hayes, Emily Sperbeck, William Milberg, Regina E. McGlinchey et al. · 2015 · Molecular Psychiatry
- Increased DNA methylation in the suicide brainHaghighi, Fatemeh, Xin, Yurong, Chanrion, Benjamin, O'Donnell, Anne H., Ge, Yongchao, Dwork, Andrew J., Arango, Victoria, Mann, J. John · 2014 · Dialogues in Clinical Neuroscience
- Intergenerational transmission of DNA methylation signatures associated with early life stressStenz, Ludwig, Schechter, Daniel S., Serpa, Sandra Rusconi, Paoloni-Giacobino, Ariane · 2018 · Current Genomics
- Early life stress in epilepsy: A seizure precipitant and risk factor for epileptogenesisJolien S. van Campen, Floor E. Jansen, Pierre N. E. De Graan, Kees P. J. Braun, Marian Joëls · 2013 · Epilepsy & Behavior
- Epigenetic mechanisms in stress and adaptationMifsud, Karen R., Gutièrrez-Mecinas, María, Trollope, Alexandra F., Collins, Andrew, Saunderson, Emily A., Reul, Johannes M.H.M. · 2011 · Brain, Behavior, and Immunity
- Serotonin transporter allelic variation in mothers predicts maternal sensitivity, behavior and attitudes toward 6-month-old infantsViara R. Mileva‐Seitz, James L. Kennedy, Leslie R. Atkinson, M. Steiner, Robert D. Levitan, Stephen G. Matthews, M. J. Meaney, Marla B. Sokolowski, A. S. Fleming · 2011 · Genes Brain & Behavior
- Childhood Sexual Abuse and Early Timing of PubertyJennie G. Noll, Penelope K. Trickett, Jeffrey D. Long, Sonya L. Negriff, Elizabeth J. Susman, Idan Shalev, Jacinda C. Li, Frank W. Putnam · 2016 · Journal of Adolescent Health
- Abnormal Epigenetic Regulation of Immune System during AgingMiriam Galvonas Jasiulionis · 2018 · Frontiers in Immunology
- Adverse Childhood Experiences Are Associated With Migraine and Vascular BiomarkersGretchen E. Tietjen, Jagdish Khubchandani, Nabeel A. Herial, Kavit B Shah · 2012 · Headache The Journal of Head and Face Pain
- Potential programming of dopaminergic circuits by early life stressRodrigues, Ana-João, Leão, Pedro, Carvalho, Miguel, Almeida, Osborne F. X., Sousa, Nuno · 2011 · Psychopharmacology
- Glucocorticoids as mediators of developmental programming effectsBatbayar Khulan, Amanda Jane Drake · 2012 · Best Practice & Research Clinical Endocrinology & Metabolism
- Childhood Abuse and Migraine: Epidemiology, Sex Differences, and Potential MechanismsGretchen E. Tietjen, Barbara Lee Peterlin · 2011 · Headache The Journal of Head and Face Pain
- Lasting effects of early exposure to temperature on the gonadal transcriptome at the time of sex differentiation in the European sea bass, a fish with mixed genetic and environmental sex determinationNoèlia Díaz, Francesc Piferrer · 2015 · BMC Genomics
- Relationship of prenatal maternal obesity and diabetes to offspring neurodevelopmental and psychiatric disorders: a narrative reviewLinghua Kong, Xinxia Chen, Mika Gissler, Catharina Lavebratt · 2020 · International Journal of Obesity
- The role of epigenetics in personalized medicine: challenges and opportunitiesMahmood Rasool, Arif Malik, Muhammad Imran Naseer, Abdul Manan, Shakeel Ahmed Ansari, Irshad Begum, Mahmood Husain Qazi, Peter Natesan Pushparaj, Adel Mohammed Abuzenadah, Mohammed Hussein Al-Qahtani et al. · 2015 · BMC Medical Genomics
- MicroRNAs in Mental Health: From Biological Underpinnings to Potential TherapiesJoshua G. Hunsberger, Daniel R. Austin, Guang Chen, Husseini K. Manji · 2009 · NeuroMolecular Medicine
- The prefrontal–limbic network in depression: Modulation by hypothalamus, basal ganglia and midbrainMaxwell R. Bennett · 2011 · Progress in Neurobiology
- Youth and young adult suicide: A study of life trajectoryMonique Séguin, Johanne Renaud, ALAIN D. LESAGE, Marie Robert, Gustavo Turecki · 2011 · Journal of Psychiatric Research
- A Framework to Examine the Role of Epigenetics in Health Disparities among Native AmericansTeresa Brockie, Morgan Michelle Heinzelmann, Jessica Gill · 2013 · Nursing Research and Practice
- Methylation matters in child development: toward developmental behavioral epigeneticsvan IJzendoorn, Marinus H, Bakermans-Kranenburg, Marian J, Ebstein, Richard P · 2011 · Child Development Perspectives
- Role of DNA methylation and the DNA methyltransferases in learning and memoryMichael J. Morris, Lisa M. Monteggia · 2014 · Dialogues in Clinical Neuroscience
- Biology, Genes, and ResilienceLucy Bowes, Sara R. Jaffee · 2013 · Trauma Violence & Abuse
- Lifetime experiences, the brain and personalized medicine: An integrative perspectiveBruce S. McEwen, Linn Getz · 2012 · Metabolism