The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin
Open accessAbstract
In a rat model of context-induced relapse to heroin, we identified sparsely distributed ventral medial prefrontal cortex (mPFC) neurons that were activated by the heroin-associated context. Selective pharmacogenetic inactivation of these neurons inhibited context-induced drug relapse. A small subset of ventral mPFC neurons formed neuronal ensembles that encode the learned associations between heroin reward and heroin-associated contexts; re-activation of these neuronal ensembles by drug-associated contexts during abstinence provoked drug relapse.
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Cites
Hebb, D. O. (2005) · doi:10.4324/9781410612403 · Cited by 9,825
Extinction circuits for fear and addiction overlap in prefrontal cortex
Peters, J., Kalivas, P. W., & Quirk, G. J. (2009) · Learning & Memory · doi:10.1101/lm.1041309 · Cited by 736
Heroin and cocaine intravenous self-administration in rats: Mediation by separate neural systems
Ettenberg, A., Pettit, H. O., Bloom, F. E., & Koob, G. F. (1982) · Psychopharmacology · doi:10.1007/bf00428151 · Cited by 563
Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking
Van den Oever, M. C., Goriounova, N. A., Wan Li, K., Van der Schors, R. C., Binnekade, R., Schoffelmeer, A. N. M., Mansvelder, H. D., Smit, A. B., Spijker, S., & De Vries, T. J. (2008) · Nature Neuroscience · doi:10.1038/nn.2165 · Cited by 206
Cited by
The nucleus accumbens: a comprehensive review
Salgado, S., & Kaplitt, M. G. (2015) · Stereotactic and Functional Neurosurgery · doi:10.1159/000368279 · Cited by 489
Stress-induced reinstatement of drug seeking: 20 years of progress
Mantsch, J. R., Baker, D. A., Funk, D., Lê, A. D., & Shaham, Y. (2016) · Neuropsychopharmacology · doi:10.1038/npp.2015.142 · Cited by 438
Self-citationBossert, J. M., Marchant, N. J., Calu, D. J., & Shaham, Y. (2013) · Psychopharmacology · doi:10.1007/s00213-013-3120-y · Cited by 453
Self-citationMa, Y.-Y., Lee, B. R., Wang, X., Guo, C., Liu, L., Cui, R., Lan, Y., Balcita-Pedicino, J. J., Wolf, M. E., Sesack, S. R., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.08.023 · Cited by 344
Self-citationGoing and stopping: dichotomies in behavioral control by the prefrontal cortex
Gourley, S. L., & Taylor, J. R. (2016) · Nature Neuroscience · doi:10.1038/nn.4275 · Cited by 195
Metadata
- Authors
- Bossert, J. M., Stern, A. L., Theberge, F. R. M., Cifani, C., Koya, E., Hope, B. T., & Shaham, Y.
- Venue
- Nature Neuroscience
- Published
- 2011-02-20
- Volume
- 14
- Issue
- 4
- Pages
- 420-422
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W2026145070
- Cited by
- 306
- References
- 4
- FWCI
- 8.10
- Type
- journal article
- Language
- en
- Open access
- green
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- Bossert, J. M., Stern, A. L., Theberge, F. R. M., Cifani, C., Koya, E., Hope, B. T., & Shaham, Y. (2011). Ventral medial prefrontal cortex neuronal ensembles mediate context-induced relapse to heroin. Nature Neuroscience. https://doi.org/10.1038/nn.2758
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