Cited by 55Olfactory and Sensory Function StudiesNeurobiology and Insect Physiology ResearchNeurogenesis and neuroplasticity mechanisms

Topographical representation of odor hedonics in the olfactory bulb

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Kermen, Florence, Midroit, Maëllie, Kuczewski, Nicola, Forest, Jérémy, Thévenet, Marc, Sacquet, Joëlle, Benetollo, Claire, Richard, Marion +2 more·2016·Nature Neuroscience

Abstract

Hedonic value is a dominant aspect of olfactory perception. Using optogenetic manipulation in freely behaving mice paired with immediate early gene mapping, we demonstrate that hedonic information is represented along the antero-posterior axis of the ventral olfactory bulb. Using this representation, we show that the degree of attractiveness of odors can be bidirectionally modulated by local manipulation of the olfactory bulb's neural networks in freely behaving mice.

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Crossref · 10.1038/nn.4317

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Authors
Kermen, F., Midroit, M., Kuczewski, N., Forest, J., Thévenet, M., Sacquet, J., Benetollo, C., Richard, M., Didier, A., & Mandairon, N.
Affiliations
Lyon 1 Université (FR)
Corresponding author
Mandairon, Nathalie
Venue
Nature Neuroscience
Published
2016-06-06
Volume
19
Issue
7
Pages
876-878
ISSN
  • 1097-6256 (ISSN-L)
  • 1546-1726
OpenAlex
W2409294965
Cited by
55
References
25
Citations by year
2026: 7 · 2025: 6 · 2024: 3 · 2023: 4 · 2022: 2 · 2021: 9 · 2020: 9 · 2019: 6 · 2018: 5 · 2017: 2 · 2016: 2
FWCI
3.70
Type
journal article
Language
en
Open access
Locations
  • Nature Neuroscience (publishedVersion)
  • PubMed (publishedVersion)
  • Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
  • HAL (submittedVersion)
Topics
  • Life Sciences › Neuroscience › Sensory Systems › Olfactory and Sensory Function Studies
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
  • Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Keywords
olfactory bulb, anterior-posterior axis, immediate early genes, optogenetics, olfactory perception, odor-guided behavior
MeSH terms
Animals, Behavior, Animal, Male, Mice, Inbred C57BL, Nerve Net, Odorants, Olfactory Bulb, Smell, Olfactory Perception

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