The DOI matches its Crossref record; 108 of the 109 references it cites were found in a registry or an index.
The neural basis of puberty and adolescence
Abstract
The pubertal transition to adulthood involves both gonadal and behavioral maturation. A developmental clock, along with permissive signals that provide information on somatic growth, energy balance and season, time the awakening of gonadotropin releasing hormone (GnRH) neurons at the onset of puberty. High-frequency GnRH release results from disinhibition and activation of GnRH neurons at puberty onset, leading to gametogenesis and an increase in gonadal steroid hormone secretion. Steroid hormones, in turn, both remodel and activate neural circuits during adolescent brain development, leading to the development of sexual salience of sensory stimuli, sexual motivation, and expression of copulatory behaviors in specific social contexts. These influences of hormones on reproductive behavior depend in part on changes in the adolescent brain that occur independently of gonadal maturation. Reproductive maturity is therefore the product of developmentally timed, brain-driven and recurrent interactions between steroid hormones and the adolescent nervous system.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“animal studies indicate that increases in reward-seeking are coincident with pubertal maturation”
From A dual systems model of adolescent risk‐taking (2010) · cites this paper as Sisk & Foster, 2004
In the citing paper
“The results for selfreported pubertal changes concur with prior research on pubertal development showing that puberty starts earlier in girls than boys (Carskadon and Acebo, 1993;Sisk and Foster, 2004;Shirtcliff et al., 2009).”
From Longitudinal Changes in Adolescent Risk-Taking: A Comprehensive Study of Neural Responses to Rewards, Pubertal Development, and Risk-Taking Behavior (2015) · cites this paper as Sisk and Foster, 2004
In the citing paper
“that some are indirectly attributable to them (in that the presence of gonadal hormones may catalyze other processes)”
From A behavioral scientist looks at the science of adolescent brain development (2010) · cites this paper as Sisk & Foster, 2004
In the citing paper
“that some are merely coincident with them, perhaps programmed to unfold along a developmental schedule established long before adolescence”
From A behavioral scientist looks at the science of adolescent brain development (2010) · cites this paper as Sisk & Foster, 2004
In the citing paper
“Animal studies suggest that some of the changes in dopaminergic activity are directly attributable to the hormonal changes of puberty”
From A behavioral scientist looks at the science of adolescent brain development (2010) · cites this paper as Sisk & Foster, 2004
In the citing paper
“These processes of restructuring in the pubertal brain are argued to be driven by hormonal changes (Sisk and Foster 2004;Sisk and Zehr 2005;Schulz et al. 2009) and to carry functional consequences on higher order brain functions such as executive functions and social cognition”
From Developmental Changes in Organization of Structural Brain Networks (2013) · cites this paper as Sisk and Foster 2004
In the citing paper
“Sexual behavior develops according to a species-specific, genetically controlled, maturational plan in which the age at first reproduction occurs within a specific age range (87).”
From Emerging Adulthood, a Pre-adult Life-History Stage (2020) · cites this paper as [87]
In the citing paper
“Traditionally, puberty is defined as the process leading to the attainment of sexual maturation [181], beginning with the activation of the HPG axis, and ending with reproductive competency [153, 178].”
From The neuroendocrine control of the circadian system: Adolescent chronotype (2012) · cites this paper as [178]
Citations
Cites
The Physiology of Reproduction
Legendre, M., & Jalabert, B. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-109-2-176_1 · Cited by 7,876
Dynamic mapping of human cortical development during childhood through early adulthood
Gogtay, N., Giedd, J. N., Lusk, L., Hayashi, K. M., Greenstein, D., Vaituzis, A. C., Nugent, T. F., Herman, D. H., Clasen, L. S., Toga, A. W., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402680101 · Cited by 5,604
Brain development during childhood and adolescence: a longitudinal MRI study
Giedd, J. N., Blumenthal, J., Jeffries, N. O., Castellanos, F. X., Liu, H., Zijdenbos, A., Paus, T., Evans, A. C., & Rapoport, J. L. (1999) · Nature Neuroscience · doi:10.1038/13158 · Cited by 5,552
The adolescent brain and age-related behavioral manifestations
Spear, L. P. (2000) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(00)00014-2 · Cited by 5,433
The GPR54 Gene as a Regulator of Puberty
Seminara, S. B., Messager, S., Chatzidaki, E. E., Thresher, R. R., Acierno, J. S., Shagoury, J. K., Bo-Abbas, Y., Kuohung, W., Schwinof, K. M., Hendrick, A. G., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa035322 · Cited by 2,557
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
de Roux, N., Genin, E., Carel, J.-C., Matsuda, F., Chaussain, J.-L., & Milgrom, E. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1834399100 · Cited by 2,431
Trajectories of brain development: point of vulnerability or window of opportunity?
Andersen, S. L. (2003) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(03)00005-8 · Cited by 1,503
In vivo evidence for post-adolescent brain maturation in frontal and striatal regions
Sowell, E. R., Thompson, P. M., Holmes, C. J., Jernigan, T. L., & Toga, A. W. (1999) · Nature Neuroscience · doi:10.1038/13154 · Cited by 1,439
Schizophrenia: Caused by a fault in programmed synaptic elimination during adolescence?
Feinberg, I. (1982) · Journal of Psychiatric Research · doi:10.1016/0022-3956(82)90038-3 · Cited by 1,395
The physiology of male sexual behavior
Meisel, R. (1994) · Medical Entomology and Zoology · Cited by 988
Flagged first, then by citations
1 of the 109 references couldn’t be matched to a known paper.
Research works printed but not linked: 7
- Foster, D.L., Ebling, F.J. & Claypool, L.E. Timing of puberty by photoperiod. Reprod. Nutr. Dev. 28, 349–364 (1988). · DOI
- Wood, R.I., Robinson, J.E., Forsdike, R.A., Padmanabhan, V. & Foster, D.L. Sexual differentiation of the timing of sexual maturation in sheep. in The Onset of Puberty in Perspective (eds. Bourguignon, J.-P. & Plant, T.M.) 269–287 (Elsevier, Amsterdam, 2000).
- Plant, T. Puberty in primates. in The Physiology of Reproduction (eds. Knobil, E. & Neill, J.) 453–485 (Raven Press, New York, 1994).
- Ojeda, S. & Urbanski, H. Puberty in the rat. in The Physiology of Reproduction (eds. Knobil, E. & Neill, J.) 452–485 (Raven Press, New York, 1994).
- Foster, D. Puberty in the sheep. in The Physiology of Reproduction (eds. Knobil, E. & Neill, J.) 411–451 (Raven Press, New York, 1994).
- Petersen, S., McCrone, S., Coy, D., Adelman, J. & Mahan, L. GABAa receptor subunit mRNA in cells of the preoptic area: colocalization with LHRH mRNA using dual-label in situ hybridization histochemistry. Endocr. J. 1, 29–34 (1993).
- Pfaff, D.W., Schwartz-Giblin, S., McCarthy, M.M. & Kow, L.-M. Cellular and molecular mechanisms of female reproductive behaviors. in The Physiology of Reproduction (eds. Knobil, E. & Neill, J. D.) 107–220 (Raven Press, New York, 1994).
Cited by
Sorted by citations
Items 301–400 of 995
Steroid Hormone Entry into the Brain Requires a Membrane Transporter in Drosophila
Okamoto, N., & Yamanaka, N. (2020) · Current Biology · doi:10.1016/j.cub.2019.11.085 · Cited by 54
Constantin, S., Jasoni, C. L., Wadas, B. C., & Herbison, A. E. (2009) · Endocrinology · doi:10.1210/en.2009-0817 · Cited by 49
Metabolic control of puberty: 60 years in the footsteps of Kennedy and Mitra’s seminal work
Anderson, G. M., Hill, J. W., Kaiser, U. B., Navarro, V. M., Ong, K. K., Perry, J. R. B., Prévot, V., Tena‐Sempere, M., & Elias, C. F. (2023) · Nature Reviews Endocrinology · doi:10.1038/s41574-023-00919-z · Cited by 55
“Most of the metabolic and reproductive effects of POMC neurons are mediated by the actions of αmelanocytestimulating hormone (αMSH) on melanocortin receptors 3 and 4 (MC3R and MC4R) 123 .”
The Impact of Puberty and Social Anxiety on Amygdala Activation to Faces in Adolescence
Ferri, J. M., Bress, J. N., Eaton, N. R., & Proudfit, G. H. (2014) · Developmental Neuroscience · doi:10.1159/000363736 · Cited by 49
Sex differences in the adolescent brain and body: Findings from the saguenay youth study
Paus, T., Wong, A. P., Syme, C. A., & Pausová, Z. (2016) · Journal of Neuroscience Research · doi:10.1002/jnr.23825 · Cited by 47
“It is essential to recognize that gonadal (puberty) and social (adolescence) maturation are two distinct, albeit interacting, processes with separate timing (Sisk and Foster, 2004).”
BackgroundClark, A. S., Costine, B. A., Jones, B., Kelton‐Rehkopf, M. C., Meerts, S. H., Nutbrown-Greene, L. L., Penatti, C. A. A., Porter, D. M., Yang, P. G., & Henderson, L. (2006) · Brain Research · doi:10.1016/j.brainres.2006.08.081 · Cited by 48
Spergel, D. J. (2007) · Endocrinology · doi:10.1210/en.2006-1693 · Cited by 48
The neurobehavioral teratology of retinoids: A 50‐year history
Adams, J. (2010) · Birth Defects Research Part A Clinical and Molecular Teratology · doi:10.1002/bdra.20721 · Cited by 48
The secret codes of mammalian scents
Ferrero, D. M., & Liberles, S. D. (2009) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.39 · Cited by 49
Developmental Changes in Adolescence and Risks for Delinquency
Barbot, B., & Hunter, S. R. (2012) · Springer eBooks · doi:10.1007/978-1-4614-0905-2_2 · Cited by 50
Nakata, M., Sano, K., Musatov, S. A., Yamaguchi, N., Sakamoto, T., & Ogawa, S. (2016) · eNeuro · doi:10.1523/eneuro.0155-15.2016 · Cited by 47
“These findings suggest that ER in each site is differently involved in the regulation of sexual and aggressive behaviors, through either organizational action during pubertal period (Schulz et al., 2004; Sisk and Foster, 2004; Sisk, 2015) or activational action at the time of testing in adult.”
BackgroundChen, F. R., & Raine, A. (2017) · Aggressive Behavior · doi:10.1002/ab.21720 · Cited by 51
“…the hormone-activated remodeling of the dopaminergic pathway, early maturing individuals would have a heightened reward-oriented behavioral tendency and lower capacity of emotion regulation than their on-time/late-maturing counterparts (Sisk & Foster, 2004; Sisk & Zehr, 2005; Steinberg, 2008).”
BackgroundDevelopmental Risk I: Depression and the Developing Brain
Weir, J. M., Zakama, A. K., & Rao, U. (2012) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2012.01.004 · Cited by 54
Haj-Mirzaian, A., Amiri, S., Kordjazy, N., Momeny, M., Razmi, A., Rahimi-Balaei, M., Amini-Khoei, H., Haj-Mirzaian, A., Marzban, H., Mehr, S. E., et al. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.12.024 · Cited by 46
“Adolescence is a pivotal period for brain development accompanied with cortico-limbic maturation (Sisk and Foster, 2004).”
BackgroundJoos, C. M., Wodzinski, A., Wadsworth, M. E., & Dorn, L. D. (2018) · Developmental Review · doi:10.1016/j.dr.2018.05.001 · Cited by 47
Liu, J., You, Q.-L., Wei, M.-D., Wang, Q., Luo, Z.-Y., Lin, S., Huang, L., Li, S., Li, X., & Gao, T. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8917-0 · Cited by 45
“Adolescence is a transitional stage of physical and psychological human development that generally occurs from puberty to legal adulthood [5, 6].”
BackgroundThe Variability of Neural Responses to Naturalistic Videos Change with Age and Sex
Petroni, A., Cohen, S. S., Ai, L., Langer, N., Henin, S. E., Vanderwal, T., Milham, M. P., & Parra, L. C. (2018) · eNeuro · doi:10.1523/eneuro.0244-17.2017 · Cited by 49
“The difference in neural variability may also be due to pubertal stage, since it is known that females reach pubertal maturity 2–3 yr before males (Sisk and Foster, 2004).”
BackgroundKlinger, K., Gomes, F. V., Rincón-Cortés, M., & Grace, A. (2019) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2019.07.134 · Cited by 37
“Given that adolescence is a phase during which genetic and environmental dynamics lead to the maturation of the developing brain, the brain is particularly sensitive to disruptive factors which can lead to psychiatric disorders (Sisk and Foster, 2004; Spear, 2000; Thompson et al., 2004).”
BackgroundDevelopment of sex differences in the human brain
Kurth, F., Gaser, C., & Eileen Luders, A. (2020) · Cognitive Neuroscience · doi:10.1080/17588928.2020.1800617 · Cited by 50
“…differences, even though the results from imaging studies remain somewhat conflicting (for reviews see Arnold, 2020; Blakemore et al., 2010; Herting & Sowell, 2017; Giedd et al., 2012; Lenroot & Giedd, 2010; McCarthy & Arnold, 2011; Sisk & Foster, 2004; Sisk & Zehr, 2005; Vijayakumar et al., 2018).”
GABA System Modifications During Periods of Hormonal Flux Across the Female Lifespan
Gilfarb, R. A., & Leuner, B. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.802530 · Cited by 54
Carpenter, R. E., Maruska, K. P., Becker, L., & Fernald, R. D. (2014) · PLoS ONE · doi:10.1371/journal.pone.0096632 · Cited by 43
“istics arising from production of sex-steroids [67,68].”
Physiological Response to Social Evaluative Threat in Adolescents with Autism Spectrum Disorder
Edmiston, E. K., Jones, R. M., & Corbett, B. A. (2016) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-016-2842-1 · Cited by 43
“Pubertal development plays an important role in the physiological response to stress, both in terms of the development and stabilization of biological systems underlying the stress response, but also regarding the increased salience and complexity of social stimuli during adolescence, which is defined by the onset of…”
BackgroundHoffmann, H. M. (2018) · Journal of Visualized Experiments · doi:10.3791/58352 · Cited by 47
White matter alterations at pubertal onset
Genc, S., Seal, M. L., Dhollander, T., Malpas, C. B., Hazell, P., & Silk, T. J. (2017) · NeuroImage · doi:10.1016/j.neuroimage.2017.05.017 · Cited by 46
“…such as activation of the hypothalamic-pituitary-adrenal (HPA) and -gonadal (HPG) axes leads to increased production of adrenal and gonadal steroid hormones, which have been shown to enter the blood brain barrier and initiate remodelling of the brain in animal models (Sisk and Foster, 2004).”
Cardoso, R. C., West, S. M., Maia, T. S., Alves, B. R. C., & Williams, G. L. (2020) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2020.106434 · Cited by 43
Sex-differences in grey–white matter structure in normal-reading and dyslexic adolescents
Sandu, A., Specht, K., Beneventi, H., Lundervold, A., & Hugdahl, K. (2008) · Neuroscience Letters · doi:10.1016/j.neulet.2008.04.022 · Cited by 42
Considerations for imaging the adolescent brain
Galván, A., Leijenhorst, L. V., & McGlennen, K. M. (2012) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2012.02.002 · Cited by 50
Salas-Ramirez, K. Y., Montalto, P. R., & Sisk, C. L. (2007) · Hormones and Behavior · doi:10.1016/j.yhbeh.2007.11.004 · Cited by 42
“Adolescence is the developmental transition from childhood to adulthood and it encompasses reproductive, neural, and behavioral maturation (Andersen, 2003; Casey et al., 2000; Lenroot et al., 2007; Sisk and Foster, 2004; Sisk and Zehr, 2005; Spear, 2000; Yurgelun-Todd, 2007).”
InfluentialSelf-citationAutism as the Early Closure of a Neuroplastic Critical Period Normally Seen in Adolescence
Berger, J. M., Rohn, T. T., & Oxford, J. T. (2012) · Biological Systems Open Access · doi:10.4172/2329-6577.1000118 · Cited by 43
“Hormonal influence during this time of sexual maturation also has long-lasting structural impact on neural plasticity and remodeling of cortical and limbic neural circuits [54-56].”
BackgroundNicholls, A. R., Polman, R. C. J., Morley, D., & Taylor, N. J. (2009) · Journal of Sport and Exercise Psychology · doi:10.1123/jsep.31.3.299 · Cited by 49
“Puberty has been defined as “the activation of the hypothalamic-pituitary-gonadal axis (HPGA) that culminates in gonadal maturation” (Sisk & Foster, 2004, p. 1040).”
BackgroundJoyce, A., Elphick, H., Farquhar, M., Gringras, P., Evans, H. J., Bucks, R. S., Kreppner, J., Kingshott, R. N., Martin, J. K., Reynolds, J., et al. (2019) · Behavioral Sleep Medicine · doi:10.1080/15402002.2019.1641501 · Cited by 44
“Due to the relatively late maturation of the prefrontal cortex throughout childhood and adolescence (Sisk & Foster, 2004), untreated OSA in early childhood could restrict long-term cognitive potential through alteration of prefrontal cortex neuronal integrity.”
BackgroundOtt, L. R., Penhale, S. H., Taylor, B. K., Lew, B. J., Wang, Y., Calhoun, V. D., Stephen, J. M., & Wilson, T. W. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.118552 · Cited by 42
“These changes are especially robust during the onset of puberty (typically from 8 to 16 years old; Blakemore et al., 2010; Giedd et al., 1999; Sisk and Foster, 2004; Stephen et al., 2021).”
Neuroendocrine disruption: Historical roots, current progress, questions for the future
Gore, A. C., & Patisaul, H. B. (2010) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2010.07.003 · Cited by 42
“Later in life at puberty and into adulthood, the developing adrenals and gonads begin to produce increasing levels of steroids, which continue to organize and then activate those pathways formed at birth [11].”
BackgroundPerceived pubertal timing and recent substance use among adolescents: a longitudinal perspective
Cance, J. D., Ennett, S. T., Morgan‐López, A. A., Foshee, V. A., & Talley, A. E. (2013) · Addiction · doi:10.1111/add.12214 · Cited by 42
“One hypothesis is that early developers are the first group to experience the structural brain changes linked to the surge of hormones during puberty, which may be related to early engagement in substance use (64).”
BackgroundDahl, R. E., & Hariri, A. R. (2005) · Journal of Research on Adolescence · doi:10.1111/j.1532-7795.2005.00102.x · Cited by 45
Pubertal shifts in adrenal responsiveness to stress and adrenocorticotropic hormone in male rats
Romeo, R. D., Minhas, S., Svirsky, S. E., Hall, B. S., Savenkova, M. I., & Karatsoreos, I. N. (2014) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2014.01.016 · Cited by 41
“Puberty is marked by many changes in neuroendocrine processes, resulting in significant and extensive influences on an organism’s physiological and neurobehavioral function (Grumbach, 2002; Sisk and Foster, 2004; Romeo, 2005).”
BackgroundEEG–BOLD correlations during (post-)adolescent brain maturation
Lüchinger, R., Michels, L., Martin, E., & Brandeis, D. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.02.050 · Cited by 46
“However, late maturation, during and after adolescence, has attracted increasing attention in recent years (Blakemore and Choudhury, 2006; Sisk and Foster, 2004).”
BackgroundSex Differences Through a Neuroscience Lens: Implications for Business Ethics
Ryan, L. V. (2016) · Journal of Business Ethics · doi:10.1007/s10551-016-3110-1 · Cited by 42
“In utero, fetal development includes exposure to steroids that sexually differentiate and ‘‘organize’’ the brain’s neural structures; at puberty, those structures are ‘‘activated’’ and reorganized by gonadal steroids to prepare for adulthood (Sisk and Foster 2004).”
BackgroundMemmott‐Elison, M. K., Padilla‐Walker, L. M., Yorgason, J. B., & Coyne, S. M. (2020) · Journal of Adolescence · doi:10.1016/j.adolescence.2020.02.001 · Cited by 48
Role of GABA in the Mechanism of the Onset of Puberty in Non‐Human Primates
Terasawa, E. (2005) · International review of neurobiology · doi:10.1016/s0074-7742(05)71005-9 · Cited by 41
“Recently, a concept has been proposed that the maturation of the hypothalamus, responsible for puberty, may occur independently from the maturation of the cortices, but there may be common mechanisms governing the maturation of reproductive function and behaviors (Sisk and Foster, 2004).”
BackgroundPrenatal androgen blockade accelerates pubertal development in male rhesus monkeys
Herman, R. A., Zehr, J. L., & Wallen, K. (2005) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2005.06.004 · Cited by 40
“The neurobiological mechanisms controlling the onset of puberty are still not fully understood (reviewed in Plant, 2001; Terasawa and Fernandez, 2001; Sisk and Foster, 2004).”
BackgroundInterplay between hormones and exercise on hippocampal plasticity across the lifespan
Bettio, L. E. B., Thacker, J. S., Rodgers, S. P., Brocardo, P. S., Christie, B. R., & Gil-Mohapel, J. (2020) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2020.165821 · Cited by 40
Corbett, B. A., Muscatello, R. A., Kim, A., Vandekar, S., Duffus, S. H., Sparks, S., & Tanguturi, Y. C. (2022) · Autism Research · doi:10.1002/aur.2786 · Cited by 44
“The activation of these pubertal hormones facilitates the motivation for social and sexual relationships with peers in both sexes (Forbes & Dahl, 2010; Sisk & Foster, 2004).”
BackgroundSex Difference of Gut Microbiota
Kim, N. (2022) · Springer eBooks · doi:10.1007/978-981-19-0120-1_22 · Cited by 42
Zovkic, I. B., Waters, P., & McCormick, C. M. (2009) · Developmental Psychobiology · doi:10.1002/dev.20381 · Cited by 40
A Biopsychosocial Perspective of Adolescent Health and Disease
Sales, J. M., & Irwin, C. E. (2013) · Springer eBooks · doi:10.1007/978-1-4614-6633-8_2 · Cited by 38
“Hormones are necessary to activate neural circuitry dedicated to sexuality (Shirtcliff, 2009 ; Sisk & Foster, 2004 ) , but are no longer necessary once individuals become sexually experienced (Shirtcliff, 2009 ) .”
BackgroundGrowing Up or Growing Old? Cellular Aging Linked With Testosterone Reactivity to Stress in Youth
Drury, S. S., Shachet, A., Brett, Z. H., Wren, M. E., Esteves, K. C., Shirtcliff, E. A., Phan, J., Mabile, E., & Theall, K. P. (2014) · The American Journal of the Medical Sciences · doi:10.1097/maj.0000000000000299 · Cited by 41
Age at Menarche and First Pregnancy Among Psychosocially At-Risk Adolescents
Dunbar, J., Sheeder, J. L., Lezotte, D. C., Dabelea, D., & Stevens–Simon, C. (2008) · American Journal of Public Health · doi:10.2105/ajph.2007.120444 · Cited by 39
Greimel, E., Bakos, S., Landes, I., Töllner, T., Bartling, J., Kohls, G., & Schulte‐Körne, G. (2018) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-018-0570-z · Cited by 40
“Because females go through puberty earlier than males (Sisk & Foster, 2004), these cortical changes are more advanced in adolescent girls than in boys of the same age.”
BackgroundBorsoï, M., Manduca, A., Bara, A., Lassalle, O., Pélissier‐Alicot, A., & Manzoni, O. J. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00023 · Cited by 39
Emotional development in eating disorders: A qualitative metasynthesis
Henderson, Z. B., Fox, J. R. E., Trayner, P., & Wittkowski, A. (2019) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.2365 · Cited by 39
“…suggests that certain genetic and constitutional risk factors, including puberty changes (see Kaye et al., 2005; Kaye, Frank, Bailer, & Henry, 2005; Sisk & Foster, 2004; Treasure, 2007), make individuals more sensitive to negative emotional cues and that this coupled with a stressful life event;…”
BackgroundPerry, R. E., Rincón‐Cortés, M., Braren, S. H., Brandes-Aitken, A. N., Opendak, M. M., Pollonini, G., Chopra, D., Raver, C. C., Alberini, C. M., Blair, C., et al. (2019) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2019.100716 · Cited by 40
“We assessed if this rodent model of scarcity-adversity would produce altered social behavior and HPA axis activity in peri-adolescence, a transitional time which encompasses the maturation of social behavior (Sisk and Foster, 2004) and is increasingly understood to be a sensitive period for programming of HPA function…”
Urbanicity, biological stress system functioning and mental health in adolescents
Evans, B. E., Huizink, A. C., Greaves‐Lord, K., Tulen, J. H. M., Roelofs, K., & van der Ende, J. (2020) · PLoS ONE · doi:10.1371/journal.pone.0228659 · Cited by 42
The Role of Nutrition in Children's Neurocognitive Development, From Pregnancy Through Childhood
Nyaradi, A., Li, J., Hickling, S., Foster, J. K., & Oddy, W. H. (2015) · Apple Academic Press eBooks · doi:10.1201/b18040-5 · Cited by 38
Ohga, H., Adachi, H., Matsumori, K., Kodama, R., Nyuji, M., Selvaraj, S., Kato, K., Yamamoto, S., Yamaguchi, A., & Matsuyama, M. (2014) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2014.09.012 · Cited by 39
“The activation of pulsatile hypothalamic gonadotropin-releasing hormone (GnRH) secretion is a key event in the onset of puberty (Terasawa and Fernandez, 2001; Sisk and Foster, 2004).”
BackgroundPuberty: Its Role In Development
Susman, E. J., & Dorn, L. D. (2009) · Handbook of Adolescent Psychology · doi:10.1002/9780470479193.adlpsy001006 · Cited by 39
Neural architecture supporting active emotion processing in children: A multivariate approach
Camacho, M. C., Karim, H. T., & Perlman, S. B. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.12.013 · Cited by 37
“…of the children included in the study are too young to likely be starting puberty, future work examining emotion processing from childhood into adolescence should collect this information, particularly since boys and girls tend to progress through puberty at different rates (Sisk and Foster, 2004).”
Sugianto, N. A., Newman, C., Macdonald, D. W., & Buesching, C. D. (2019) · PLoS ONE · doi:10.1371/journal.pone.0203910 · Cited by 38
Perry, R. E., Braren, S. H., Rincón‐Cortés, M., Brandes-Aitken, A. N., Chopra, D., Opendak, M. M., Alberini, C. M., Sullivan, R. M., & Blair, C. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.02472 · Cited by 47
“We tested this using a peer socialization intervention spanning from time of weaning until time of testing in peri-adolescence, a developmental period which encompasses the maturation of social behavior and is increasingly thought of as a period in which neurodevelopment is sensitive to social experiences (Sisk and Fo…”
MethodFrère, P., Vetter, N. C., Artiges, É., Filippi, I., Miranda, R., Vulser, H., Martinot, M. P., Ziesch, V., Conrod, P., Cattrell, A., et al. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.116441 · Cited by 43
Corbett, B. A., Muscatello, R. A., Kim, A., Patel, K., & Vandekar, S. (2020) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2020.105115 · Cited by 38
“The biopsychosocial changes in puberty contribute to heightened activation of the HPA axis and increased cortisol in response to perceived stressors (Gunnar et al., 2009; Sisk and Foster, 2004).”
BackgroundThe Stability of Perceived Pubertal Timing Across Adolescence
Cance, J. D., Ennett, S. T., Morgan‐López, A. A., & Foshee, V. A. (2011) · Journal of Youth and Adolescence · doi:10.1007/s10964-011-9720-0 · Cited by 37
Sex Differences in Parietal Lobe Structure and Development
Salinas, J., Mills, E., Conrad, A. L., Koscik, T. R., Andreasen, N. C., & Nopoulos, P. (2012) · Gender Medicine · doi:10.1016/j.genm.2012.01.003 · Cited by 36
“The effects of sex hormones during brain development are well studied in both the non-human and human samples [5, 43, 44].”
BackgroundBell, M. R., Hart, B. G., & Gore, A. C. (2015) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2015.11.024 · Cited by 37
“Juvenile development is also a time of continued sensitivity to organizational effects of gonadal hormones, as well as activation of neural pathways that were organized earlier in life (Schulz et al., 2009; Sisk and Foster, 2004).”
BackgroundSharma, R., Rooke, J., Kolmogorova, D., Melanson, B. A., Mallet, J., Matar, C., Schwarz, J. M., & Ismail, N. (2018) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2018.07.012 · Cited by 40
Puberty and the Evolution of Developmental Science
Worthman, C. M., Dockray, S., & Marceau, K. (2019) · Journal of Research on Adolescence · doi:10.1111/jora.12411 · Cited by 40
Kemirembe, K., Liebmann, K., Bootes, A. M., Smith, W. A., & Suzuki, Y. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044429 · Cited by 37
“For instance, we know which neuroendocrine regulators are involved during molting and metamorphosis in insects and puberty in humans [3,4,5,6].”
BackgroundPauli‐Pott, U., & Becker, K. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.04.011 · Cited by 39
Brosda, J., Dietz, F., & Koch, M. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.07.008 · Cited by 37
“Such a decrease in dendritic spine densitymay provide a reasonable explanation for the observed PPI deficits after reelin silencing during puberty, a period characterized by neuronal maturation (De Bellis et al., 2001; Graaf-Peters and Hadders-Algra, 2006; Sisk and Foster, 2004; Spear, 2000), whereas the disturbed inf…”
BackgroundDifferential effects of nicotine exposure on the hippocampus across lifespan
Zeid, D., Kutlu, M. G., & Gould, T. J. (2018) · Current Neuropharmacology · doi:10.2174/1570159x15666170714092436 · Cited by 36
“It should be noted that, although sex-dependent effects of nicotine exposure on the hippocampus are more often associated with nicotine exposure in puberty or beyond, neural sexual differentiation begins in utero and may explain differential effects of prenatal exposure in males and females [48].”
BackgroundEnduring influence of pubertal stressors on behavioral response to hormones in female mice
Blaustein, J. D., & Ismail, N. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.01.015 · Cited by 37
“That is, puberty refers to the developmental transition to a reproductive state culminating in reproductive competence (Sisk and Foster, 2004; Waylen and Wolke, 2004), while adolescence refers to social and cognitive maturation (Sisk and Foster, 2004).”
BackgroundMethodInfluentialNeuroendocrine signaling pathways and the nutritional control of puberty in heifers
Cardoso, R. C., Alves, B. R. C., & Williams, G. L. (2018) · Animal Reproduction · doi:10.21451/1984-3143-ar2018-0013 · Cited by 46
“Pubertal maturation in female mammals is an intricate physiological process that involves physical and behavioral changes associated with activation of the hypothalamic-pituitary-ovarian axis and subsequent establishment of reproductive cyclicity (Sisk and Foster, 2004).”
BackgroundEmotion modulation of the body-selective areas in the developing brain
Ross, P. D., de Gelder, B., Crabbe, F., & Grosbras, M. (2019) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2019.100660 · Cited by 36
Zeng, J., Huynh, N., Phelps, B., & King‐Jones, K. (2020) · PLoS Biology · doi:10.1371/journal.pbio.3000609 · Cited by 33
“Steroid hormones are phylogenetically ancient signaling molecules found in animals and plants alike, where they control a wide range of developmental and physiological processes, such as sexual maturation, reproduction, glucose, and cholesterol metabolism as well as inflammatory responses [1,2].”
BackgroundGenc, S., Malpas, C. B., Gülenç, A., Sciberras, E., Efron, D., Silk, T. J., & Seal, M. L. (2020) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2020.100853 · Cited by 37
“These differences could plausibly be a signature of anatomical sex differences between males and females, potentially induced by early perinatal exposure to testosterone (Sisk and Foster, 2004).”
BackgroundHewes, R. S., Gu, T., Brewster, J. A., Qu, C., & Zhao, T. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1759-06.2006 · Cited by 36
“The resulting changes in the gain of neuropeptide signaling form an integral component of the neuroendocrine and physiological feedback loops that establish and regulate homeostatic mechanisms (Jequier, 2002; Meerlo et al., 2002; Plant and Shahab, 2002; Sisk and Foster, 2004).”
BackgroundConstantin, S. (2011) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2011.02130.x · Cited by 41
The importance of affective development for the emergence of depressive disorders during adolescence
Allen, N. B., & Sheeber, L. (2008) · doi:10.1017/cbo9780511551963.001 · Cited by 37
Mathematical modeling of gonadotropin-releasing hormone signaling
Pratap, A., Garner, K. L., Voliotis, M., Tsaneva-Atanasova, K., & McArdle, C. A. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2016.08.022 · Cited by 35
“For example, changes in GnRH pulse frequency drive changes in reproductive status during development, with an increase in pulse frequency driving the increased gametogenesis and gonadal steroid production at puberty (Sisk and Foster, 2004).”
Influence of Heart Rate, Age, and Gender on Heart Rate Variability in Adolescents and Young Adults
Estévez‐Báez, M., Naranjo, C. C., Jas-García, J. D., Rodríguez-Ríos, E., Machado, C., Montes-Brown, J., Leisman, G., Schiavi, A. J., Machado, A., Luaces, C. S., et al. (2018) · Advances in experimental medicine and biology · doi:10.1007/5584_2018_292 · Cited by 34
Assessing risk in adolescent sexual offenders: recommendations for clinical practice
Vitacco, M. J., Caldwell, M. F., Ryba, N. L., Malesky, A., & Kurus, S. J. (2009) · Behavioral Sciences & the Law · doi:10.1002/bsl.909 · Cited by 37
Strait, G. G., McQuillin, S. D., Smith, B. H., & Englund, J. A. (2012) · Advances in School Mental Health Promotion · doi:10.1080/1754730x.2012.736789 · Cited by 38
“These changes are partly due to the increased release of gonadal steroids (e.g. androgen) at the onset of puberty and the densely packed gonadal steroid receptors populating the affective node (Sisk & Foster, 2004).”
BackgroundPerica, M. I., & Luna, B. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105378 · Cited by 35
Murray, E., Smith, K. B., Stoby, K. S., Thomas, B. J., Swenson, M. J., Arber, L., Frenette, E., & Ismail, N. (2019) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2019.104481 · Cited by 34
Rami, Y., Ebrahimpour, K., Maghami, M., Shoshtari-Yeganeh, B., & Kelishadi, R. (2021) · Biological Trace Element Research · doi:10.1007/s12011-021-02947-0 · Cited by 34
Androgens and Androgen Receptors as Determinants of Vascular Sex Differences Across the Lifespan
Lucas-Herald, A. K., & Touyz, R. M. (2022) · Canadian Journal of Cardiology · doi:10.1016/j.cjca.2022.09.018 · Cited by 35
Craemer, S. D., Croes, K., Larebeke, N. V., Henauw, S. D., Schoeters, G. E. R., Govarts, E., Loots, I., Nawrot, T. S., Nelen, V., Hond, E. D., et al. (2017) · Environment International · doi:10.1016/j.envint.2017.02.014 · Cited by 34
Corbett, B. A., Muscatello, R. A., Tanguturi, Y. C., McGinn, E., & Ioannou, S. (2019) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-019-04192-w · Cited by 35
“Puberty, on the other hand, refers to biological maturation, particularly that of sexual systems, and the physiological effects of resultant changes to the endocrine system including activation of the hypothalamic pituitary gonadal (HPG) axis (Sisk and Foster 2004) contributing to the development of secondary sexual c…”
BackgroundChristensen, C., Koyama, T., Nagy, S., Danielsen, E. T., Texada, M. J., Halberg, K. A., & Rewitz, K. (2020) · Development · doi:10.1242/dev.188110 · Cited by 33
“INTRODUCTION The activation of a neuroendocrine axis leading to the production of steroid hormones is a conserved trigger of maturation onset in animals (Rewitz et al., 2013; Sisk and Foster, 2004; Tennessen and Thummel, 2011).”
BackgroundKeeley, R. J., Trow, J., & McDonald, R. J. (2015) · Neuroscience · doi:10.1016/j.neuroscience.2015.07.024 · Cited by 33
Mueller, S. C., Mandell, D., Leschek, E., Pine, D. S., Merke, D. P., & Ernst, M. (2009) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2008.031 · Cited by 33
“During development, hormonal effects can manifest as long-term effects that affect the organization of the neural circuitry or as short-term changes occurring only when hormones are pres-ent (Sisk and Foster 2004).”
Post-adolescent developmental changes in cortical complexity
Sandu, A., Izard, E., Specht, K., Beneventi, H., Lundervold, A., & Ystad, M. A. (2014) · Behavioral and Brain Functions · doi:10.1186/1744-9081-10-44 · Cited by 33
“This dimorphism in brain structure development has been explained through physiological changes during brain development related to the action on sex steroid receptors [15-17], with adolescence being the age where the majority of steroid-dependent remodelling brain changes take place [18].”
BackgroundAge of exposure-dependent effects of amphetamine on behavioral flexibility
Hankosky, E. R., Kofsky, N. M., & Gulley, J. M. (2013) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.06.002 · Cited by 32
“[3] Sisk CL, Foster DL.”
Wong, A. P., French, L., Leonard, G. T., Perron, M., Pike, G. B., Richer, L., Veillette, S., Pausová, Z., & Paus, T. (2017) · Cerebral Cortex · doi:10.1093/cercor/bhx040 · Cited by 33
Cantacorps, L., González‐Pardo, H., Arias, J. L., Valverde, O., & Conejo, N. M. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.03.006 · Cited by 32
Yang, H., Liu, X., Hu, G., Xie, Y., Lin, S., Zhao, Z., & Chen, J. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.03.155 · Cited by 32
Waters, L. E., Loton, D. J., Grace, D., Jacques-Hamilton, R., & Zyphur, M. J. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.02273 · Cited by 40
“The teen, and now increasingly pre-teen, years are characterized by intense changes to a young person’s physical development, identity, social life, family relationships, exposure to drugs and alcohol, academic requirements, employment and economic responsibilities (Larson et al., 1996; Singh, 1998; Levy-Warren, 1999;…”
BackgroundFung, M. H., Taylor, B. K., Frenzel, M. R., Eastman, J. A., Wang, Y., Calhoun, V. D., Stephen, J. M., & Wilson, T. W. (2020) · Cerebral Cortex · doi:10.1093/cercor/bhaa169 · Cited by 32
Social neuroscience of child and adolescent depression
Miller, A. (2007) · Brain and Cognition · doi:10.1016/j.bandc.2006.02.008 · Cited by 30
Intelligence and salivary testosterone levels in prepubertal children
Ostatníková, D., Celec, P., Putz, Z., Hodosy, J., Schmidt, F., Laznibatová, J., & Kúdela, M. (2006) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.10.018 · Cited by 32
Metadata
- Authors
- Sisk, C. L., & Foster, D. L.
- Affiliations
- Michigan State University (US)
- University of Michigan (US)
- Corresponding author
- Sisk, Cheryl L
- ORCID
- Sisk, Cheryl L
- Venue
- Nature Neuroscience
- Published
- 2004-09-27
- Volume
- 7
- Issue
- 10
- Pages
- 1040-1047
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W2094109313
- Cited by
- 1,085
- References
- 109
- Citations by year
- 2026: 40 · 2025: 37 · 2024: 50 · 2023: 46 · 2022: 60 · 2021: 58 · 2020: 59 · 2019: 50 · 2018: 75 · 2017: 43 · 2016: 59 · 2015: 62 · 2014: 56 · 2013: 74 · 2012: 57
- FWCI
- 4.66
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Sexual Differentiation and Disorders
- Keywords
- puberty, adolescence, GnRH neurons, steroid hormones, adolescent brain development, sexual motivation, sexual behavior, reproductive maturation, neural circuits, gonadal maturation
- MeSH terms
- Adolescent, Animals, Biological Clocks, Brain, Gonads, Humans, Hypothalamo-Hypophyseal System, Gonadotropin-Releasing Hormone, Puberty, Sexual Behavior, Sex Characteristics, Sexual Maturation
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
