FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation

Welcker, Markus, Clurman, Bruce E.·2008·Nature Reviews Cancer

Cited by (1,000)

Items 601–700 of 1,000

  1. Role of FBXW7 in the quiescence of gefitinib-resistant lung cancer stem cells in EGFR-mutant non-small cell lung cancer
    Moulid Hidayat, Yoichiro Mitsuishi, Fumiyuki Takahashi, Ken Tajima, Toshifumi Yae, Katsumi Miyahara, Daisuke Hayakawa, Wira Winardi, Hiroaki Ihara, Yoshika Koinuma et al. · 2019 · Bosnian Journal of Basic Medical Sciences
  2. β-TrCP-mediated ubiquitination and degradation of liver-enriched transcription factor CREB-H
    Yun Cheng, Weiwei Gao, Hei-Man Vincent Tang, Jianjun Deng, Chi‐Ming Wong, Chi‐Ping Chan, Dong‐Yan Jin · 2016 · Scientific Reports
  3. Temporal mTOR inhibition protects Fbxw7-deficient mice from radiation-induced tumor development
    Yueyong Liu, Yurong Huang, Zeran Wang, Yong Huang, Xiaohua Li, Alexander Louie, Guangwei Wei, Jian‐Hua Mao · 2013 · Aging
  4. Enhancement of c-Myc degradation by Bloom (BLM) helicase leads to delayed tumor initiation
    Suruchika Chandra, Raina Priyadarshini, Vinoth Madhavan, Shweta Tikoo, Mansoor Hussain, Richa Mudgal, Priyanka Modi, Vivek Kumar Srivastava, Sagar Sengupta · 2013 · Journal of Cell Science
  5. FBXW7 Mutations Promote Cell Proliferation, Migration, and Invasion in Cervical Cancer
    Faying Liu, Yang Zou, Feng Wang, Bicheng Yang, Ziyu Zhang, Yong Luo, Meirong Liang, Jiangyan Zhou, Ouping Huang · 2019 · Genetic Testing and Molecular Biomarkers
  6. Microtubules in Polyomavirus Infection
    Lenka Horníková, Kateřina Bruštíková, Jitka Forstová · 2020 · Viruses
  7. Synergistic targeting of BRCA1 mutated breast cancers with PARP and CDK2 inhibition
    Diar Aziz, Neil Portman, Kristine J. Fernandez, Christine Lee, Sarah Alexandrou, Alba Llop‐Guevara, Zoe Phan, Aliza Yong, Ashleigh Wilkinson, C. Marcelo Sergio et al. · 2021 · npj Breast Cancer
  8. FBXW7 inactivation induces cellular senescence via accumulation of p53
    Longyuan Gong, Danrui Cui, Dian Liu, Xiao Z. Shen, Hui Pan, Xiufang Xiong, Yongchao Zhao · 2022 · Cell Death and Disease
  9. The G1 phase E3 ubiquitin ligase TRUSS that gets deregulated in human cancers is a novel substrate of the S-phase E3 ubiquitin ligase Skp2
    Azfar Jamal, Swarnalatha Manickavinayaham, Sarwat Sultana, Prashant Pranesh Joshi, Subrat Kumar Panda, Vijay Kumar · 2015 · Cell Cycle
  10. MCL1 meets its end during mitotic arrest
    Scott E. Millman, Michele Pagano · 2011 · EMBO Reports
  11. The Role of Glucose and Lipid Metabolism in Growth and Survival of Cancer Cells
    Charlene Brault, Almut Schulze · 2016 · Recent results in cancer research/Recent Results in Cancer Research
  12. p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress
    Slavica Tudzarova, Paul James Mulholland, Ayona Dey, Kai Stoeber, Andrei L. Okorokov, Gareth Haydn Williams · 2016 · Cell Cycle
  13. Regulation of Mammalian DNA Replication via the Ubiquitin-Proteasome System
    Tarek Abbas, Anindya Dutta · 2017 · Advances in experimental medicine and biology
  14. Biological significance and prognostic/predictive impact of complex karyotype in chronic lymphocytic leukemia
    Maurizio Cavallari, Francesco Cavazzini, Antonella Bardi, Eleonora Volta, Aurora Melandri, Elisa Tammiso, Elena Saccenti, Enrico Lista, Francesca Maria Quaglia, Antonio Urso et al. · 2018 · Oncotarget
  15. Repurposing Antibacterial AM404 As a Potential Anticancer Drug for Targeting Colorectal Cancer Stem-Like Cells
    Mehreen Ahmed, Nicholas Jinks, Roya Babaei‐Jadidi, Hossein Kashfi, Marcos Castellanos‐Uribe, Sean Tobias May, Abhik Mukherjee, Abdolrahman Shams Nateri · 2019 · Cancers
  16. Tumor Suppressor FBXW7 and Its Regulation of DNA Damage Response and Repair
    Huiyin Lan, Yi Sun · 2021 · Frontiers in Cell and Developmental Biology
  17. FBW7 regulates DNA interstrand cross-link repair by modulating FAAP20 degradation
    Jingming Wang, Ukhyun Jo, So Young Joo, Hyungjin Kim · 2016 · Oncotarget
  18. Modern Perspective on Metabolic Reprogramming in Malignant Neoplasms
    Dmitriy A. Korshunov, И. В. Кондакова, Шашова Елена Евгеньевна · 2019 · Biochemistry (Moscow)
  19. FBXW7 loss of function promotes esophageal squamous cell carcinoma progression via elevating MAP4 and ERK phosphorylation
    Yunzhi Pan, Jing Liu, Yingyin Gao, Yuqing Guo, Changxing Wang, Zhipan Liang, Meiying Wu, Yulan Qian, Yinyan Li, Jingyi Shen et al. · 2023 · Journal of Experimental & Clinical Cancer Research
  20. Trial Watch: Proteasomal inhibitors for anticancer therapy
    Florine Obrist, Gwenola Manic, Guido Kroemer, Ilio Vitale, Lorenzo Galluzzi · 2014 · Molecular & Cellular Oncology
  21. CDC4/FBXW7 and the ‘just enough’ model of tumourigenesis
    Hayley L. Belnoue-Davis, Ian P.M. Tomlinson · 2012 · The Journal of Pathology
  22. Targeting Lysophosphatidic Acid Signaling Retards Culture-Associated Senescence of Human Marrow Stromal Cells
    Masahiko Kanehira, Toshiaki Kikuchi, Shinya Ohkouchi, Taizou Shibahara, Naoki Tode, Arif Santoso, Hisayoshi Daito, Hiromitsu Ohta, Tsutomu Tamada, Toshihiro Nukiwa · 2012 · PLoS ONE
  23. Regulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2
    Tarek Abbas, Mignon Keaton, Anindya Dutta · 2013 · Cell Cycle
  24. miR-25 promotes metastasis via targeting FBXW7 in esophageal squamous cell carcinoma
    Ye Hua, Kai Zhao, Gang Tao, Chunhua Dai, Yuting Su · 2017 · Oncology Reports · Retracted
  25. Prognostic significance of tumor genotypes and CD8+ infiltrates in stage I-III colorectal cancer
    Elena Fountzilas, Vassiliki Kotoula, Ioannis Sotirios Tikas, Kyriaki Manousou, Kyriaki Papadopoulou, Christos Poulios, Vasilios Karavasilis, Ioannis Efstratiou, Dimitrios G. Pectasides, Kleo Papaparaskeva et al. · 2018 · Oncotarget
  26. SCFFBXO28-mediated self-ubiquitination of FBXO28 promotes its degradation
    Lili Cai, Liang Liu, Lihui Li, Lijun Jia · 2019 · Cellular Signalling
  27. UPS Delivers Pluripotency
    Yasutaka Okita, Keiichi I. Nakayama · 2012 · Cell stem cell
  28. FBX8 Acts as an Invasion and Metastasis Suppressor and Correlates with Poor Survival in Hepatocellular Carcinoma
    Feifei Wang, Yudan Qiao, Jiang Yu, Xiaoli Ren, Jianmei Wang, Yi� Ding, Xiaojing Zhang, Wenhui Ma, Yanqing Ding, Liang Li · 2013 · PLoS ONE
  29. Tumor Suppressor HIPK2 Regulates Malignant Growth via Phosphorylation of Notch1
    Eun‐Jung Ann, Mi‐Yeon Kim, Ji‐Hye Yoon, Ji‐Seon Ahn, Eun-Hye Jo, Hye-Jin Lee, Hyun-Woo Lee, Hyeok-Gu Kang, Dong Wook Choi, Kyung‐Hee Chun et al. · 2016 · Cancer Research
  30. Inhibitors for E3 ubiquitin ligases
    John R. Lydeard, J. Wade Harper · 2010 · Nature Biotechnology
  31. Quantitative proteomics to decipher ubiquitin signaling
    Ping‐Chung Chen, Chan Hyun Na, Junmin Peng · 2012 · Amino Acids
  32. The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis
    Arwa Aldaalis, Maria T. Bengoechea-Alonso, Johan Ericsson · 2022 · Frontiers in Oncology
  33. The Emerging Role of Ubiquitin-Specific Protease 36 (USP36) in Cancer and Beyond
    Meng-Yao Niu, Yan-Jun Liu, Jinjin Shi, Ru-Yi Chen, Shun Zhang, Chang-Yun Li, Jia-Feng Cao, Guan‐Jun Yang, Jiong Chen · 2024 · Biomolecules
  34. GSK3 is required for rapalogs to induce degradation of some oncogenic proteins and to suppress cancer cell growth
    Junghui Koo, Xuerong Wang, Taofeek Kunle Owonikoko, Suresh S. Ramalingam, Fadlo Raja Khuri, Shi‐Yong Sun · 2015 · Oncotarget
  35. Ubiquitination of Myc: Proteasomal Degradation and Beyond
    J. Müller, Martin Eilers · 2008 · Ernst Schering Research Foundation workshop/Ernst Schering Foundation Symposium proceedings
  36. PP2A-B55β Antagonizes Cyclin E1 Proteolysis and Promotes Its Dysregulation in Cancer
    YingMeei Tan, Dahui Sun, Weijian Jiang, Kathleen Klotz‐Noack, Ajay Amar Vashisht, James Akira Wohlschlegel, Martin Widschwendter, Charles Spruck · 2014 · Cancer Research
  37. Ubiquitin-Dependent Proteolysis in G1/S Phase Control and Its Relationship with Tumor Susceptibility
    John Alan Diehl, Bhaskar Ponugoti · 2010 · Genes & Cancer
  38. The emerging roles of F-box proteins in pancreatic tumorigenesis
    Hua Wang, Anirban Maitra, Huamin Wang · 2015 · Seminars in Cancer Biology
  39. Molecular alterations in lesions of anogenital mammary-like glands and their mammary counterparts including hidradenoma papilliferum, intraductal papilloma, fibroadenoma and phyllodes tumor
    Anastasia M. Konstantinova, Tomáš Vaněček, Petr Martínek, Liubov Kyrpychova, Dominic V. Spagnolo, Colin J.R. Stewart, Francesca Portelli, Michal Michal, Dmitry V. Kazakov · 2017 · Annals of Diagnostic Pathology
  40. Functional variants in DCAF4 associated with lung cancer risk in European populations
    Hongliang Liu, Zhensheng Liu, Yanru Wang, Thomas E. Stinchcombe, Kouros Owzar, Younghun Han, Rayjean J. Hung, Yonathan Brhane, John R McLaughlin, Paul Brennan et al. · 2017 · Carcinogenesis
  41. Ubiquitin-Regulated Cell Proliferation and Cancer
    Beatriz Pérez‐Benavente, Alihamze Fathinajafabadi, Rosa Farrás · 2020 · Advances in experimental medicine and biology
  42. Kaposi’s sarcoma-associated herpesvirus latency-associated nuclear antigen dysregulates expression of MCL-1 by targeting FBW7
    Yeong Jun Kim, Yuri Kim, Abhishek Kumar, Chan Woo Kim, Zsolt Tóth, Nam‐Hyuk Cho, Hye-Ra Lee · 2021 · PLoS Pathogens
  43. FBW7 increases drug sensitivity to cisplatin in human nasopharyngeal carcinoma by downregulating the expression of multidrug resistance-associated protein
    Yan Song, Xinjia Zhou, Weiliang Bai, Xiulan Ma · 2015 · Tumor Biology
  44. Ubiquitin Ligases in Cholesterol Metabolism
    Wei Jiang, Bao‐Liang Song · 2014 · Diabetes & Metabolism Journal
  45. EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor
    Mamoru Takada, Ming Zhuang, Hiroyuki Inuzuka, Jing Zhang, Giada Zurlo, Jinfang Zhang, Qing Hua Zhang · 2016 · Oncotarget
  46. FBXW 7 modulates malignant potential and cisplatin‐induced apoptosis in cholangiocarcinoma through NOTCH 1 and MCL 1
    Akiko Mori, Kunihiro Masuda, Hideo Ohtsuka, Masahiro Shijo, Kyohei Ariake, Koji Fukase, Naoaki Sakata, Masamichi Mizuma, Takanori Morikawa, Hiroki Hayashi et al. · 2018 · Cancer Science
  47. Fbxw7 haploinsufficiency loses its protection against DNA damage and accelerates MNU-induced gastric carcinogenesis
    Yannan Jiang, Xinming Qi, Xinyu Liu, Jun Zhang, Jun Feng Ji, Zhenggang Zhu, Jin Ren, Yingyan Yu · 2017 · Oncotarget
  48. FBXW4 Is Highly Expressed and Associated With Poor Survival in Acute Myeloid Leukemia
    Qi Han, Qi Zhang, Huihui Song, Yevgeniya Bamme, Chunhua Song, Zheng Ge · 2020 · Frontiers in Oncology
  49. Clinical significance of FBXW7 tumor suppressor gene mutations and expression in human colorectal cancer: a systemic review and meta-analysis
    Wei Shang, Chuanwang Yan, Ran Liu, Lili Chen, Dongdong Cheng, Liang Hao, Wenguang Yuan, Jingbo Chen, Hui Yang · 2021 · BMC Cancer
  50. Multiple Mechanisms of NOTCH1 Activation in Chronic Lymphocytic Leukemia: NOTCH1 Mutations and Beyond
    Federico Pozzo, Tamara Bittolo, Erika Tissino, Antonella Zucchetto, Riccardo Bomben, Laura Polcik, Svenja Dannewitz Prosseda, Tanja Nicole Hartmann, Valter Gattei · 2022 · Cancers
  51. Modeling Cancers in Drosophila
    Cédric Polesello, Fernando Roch, Vanessa Gobert, Marc Haenlin, Lucas Waltzer · 2011 · Progress in molecular biology and translational science
  52. A C-terminal Fragment of Cyclin E, Generated by Caspase-mediated Cleavage, Is Degraded in the Absence of a Recognizable Phosphodegron
    Dragos C. Plesca, Suparna Mazumder, Vivian Gama, Shigemi Matsuyama, Alexandru Almasan · 2008 · Journal of Biological Chemistry
  53. The hormone-bound vitamin D receptor enhances the FBW7-dependent turnover of NF-κB subunits
    Fatemeh Fekrmandi, T T Wang, John H. White · 2015 · Scientific Reports
  54. Critical role of XBP1 in cancer signalling is regulated by PIN1
    Unbin Chae, Sun-Ji Park, Bokyung Kim, Shou Wei, Ju‐Sik Min, Jun-Hyeog Lee, Se Hoon Park, Ann–Hwee Lee, Kun Ping Lu, Dong‐Seok Lee et al. · 2016 · Biochemical Journal
  55. FBXW7 E3 ubiquitin ligase: degrading, not degrading, or being degraded
    Huiyin Lan, Yi Sun · 2019 · Protein & Cell
  56. Using weighted gene co-expression network analysis to identify key modules and hub genes in tongue squamous cell carcinoma
    Ke Yin, Ying Zhang, Suxin Zhang, Yang Bao, Jie Guo, Guanhua Zhang, Tianke Li · 2019 · Medicine
  57. FBW7-mediated ubiquitination and degradation of KLF5
    Yi Luan · 2014 · World Journal of Biological Chemistry
  58. Dynamic Ubiquitination of the Mitogen-activated Protein Kinase Kinase (MAPKK) Ste7 Determines Mitogen-activated Protein Kinase (MAPK) Specificity
    Jillian H. Hurst, Henrik Gunnar Dohlman · 2013 · Journal of Biological Chemistry
  59. Ubiquitination Enzymes in Cancer, Cancer Immune Evasion, and Potential Therapeutic Opportunities
    Aiman B. Awan, Maryiam Jama Ali Osman, Omar M. Khan · 2025 · Cells
  60. Ubiquitin ligases and a processive proteasome facilitate protein clearance during the oocyte-to-embryo transition in Caenorhabditis elegans
    Caroline A. Spike, Tatsuya Tsukamoto, David Greenstein · 2022 · Genetics
  61. E3-ubiquitin ligases and recent progress in osteoimmunology
    Yosuke Asano, Yoshinori Matsumoto, Jun Wada, Robert K. Rottapel · 2023 · Frontiers in Immunology
  62. Potential therapeutic strategy for cancer: Multi-dimensional cross-talk between circRNAs and parental genes
    Xiaoyu Sun, Xinyi Zhao, Yan Xu, Yuanyuan Yan, Han Li, Minjie Wei, Miao He · 2024 · Cancer Letters
  63. Hypoxia-Inducible Factor 1 Is Activated by Dysregulated Cyclin E during Mammary Epithelial Morphogenesis
    Tanushri Sengupta, Gathi Abraham, Yanfei Xu, Bruce E. Clurman, Alex C. Minella · 2011 · Molecular and Cellular Biology
  64. The archipelago Tumor Suppressor Gene Limits Rb/E2F-Regulated Apoptosis in Developing Drosophila Tissues
    Sarah C. Nicholson, Melissa Gilbert‐Ross, Brandon Nicolay, Maxim V. Frolov, Kenneth H. Moberg · 2009 · Current Biology
  65. Predicting Response to Chemotherapy With Early-Stage Lung Cancer
    Rafael Rosell, Miquel Tarón, Bartomeu Massutí, Nuria Mederos, Ignacio Magrí, Mariacarmela Santarpía, José Miguel Sánchez · 2011 · The Cancer Journal
  66. APC, FBXW7, KRAS, PIK3CA, and TP53 Gene Mutations in Human Colorectal Cancer Tumors Frequently Detected by Next-Generation DNA Sequencing
    Cai ZX Tang XD · 2014 · Journal of Molecular and Genetic Medicine
  67. Decoding Somatic Driver Gene Mutations and Affected Signaling Pathways in Human Medulloblastoma Subgroups
    Charles T. Robbins, Mayassa J. Bou-Dargham, Kevin G. Sanchez, Matthew C. Rosen, Qing‐Xiang Amy Sang · 2018 · Journal of Cancer
  68. Characterization of Cyclin E Expression in Multiple Myeloma and Its Functional Role in Seliciclib-Induced Apoptotic Cell Death
    Liat Ben-Yehoshua Josefsberg, Katia Beider, Avichai Shimoni, Olga Ostrovsky, Michal Samookh, Amnon Peled, Arnon Nagler · 2012 · PLoS ONE
  69. Decreased expression of FBXW7 is correlated with poor prognosis in patients with esophageal squamous cell carcinoma
    Yasuhiro Naganawa, Hideyuki Ishiguro, Yoshiyuki Kuwabara, Masahiro Kimura, Akira Mitsui, Takeyasu Katada, Tatsuya Tanaka, Midori Shiozaki, Yoshitaka Fujii, Hiromitsu Takeyama · 2010 · Experimental and Therapeutic Medicine
  70. Multiple Mechanisms Inactivate the LIN-41 RNA-Binding Protein To Ensure a Robust Oocyte-to-Embryo Transition in Caenorhabditis elegans
    Caroline A. Spike, Gabriela Huelgas‐Morales, Tatsuya Tsukamoto, David Greenstein · 2018 · Genetics
  71. Endocrinological characterization of pancreatic ducts in HFD and HGD fed mice
    Wenjun Huang, SU Lian-xiu, Xiaoxi Zhang, Xiaoxiao Xu, Rong Li · 2019 · Journal of Cellular Biochemistry
  72. Molecular Landscape and Clinical Implication of CCNE1- amplified Esophagogastric Cancer
    Naryan Rustgi, Sharon Wu, Timothy Samec, Phillip Walker, Joanne Xiu, Emil Lou, Sanjay Goel, Anwaar Saeed, Ryan H. Moy · 2024 · Cancer Research Communications
  73. Genome-wide association and sequencing studies on colorectal cancer
    Sunny Hei Wong, Joseph J.�Y. Sung, Francis K.L. Chan, Ka Fai To, Simon S.M. Ng, Xiaoju Wang, Jun Qing Yu, William Ka Kei Wu · 2013 · Seminars in Cancer Biology
  74. SCF Cdc4 Enables Mating Type Switching in Yeast by Cyclin-Dependent Kinase-Mediated Elimination of the Ash1 Transcriptional Repressor
    Qingquan Liu, Brett G. Larsen, Markéta Řičicová, Stephen M. Orlicky, Hille Tekotte, Xiaojing Tang, Karen L. Craig, Adam Quiring, Thierry Le Bihan, Carl L. Hansen et al. · 2010 · Molecular and Cellular Biology
  75. GSK3 regulates the expressions of human and mouse c-Myb via different mechanisms
    Kyoko Kitagawa, Yojiro Kotake, Yoshihiro Hiramatsu, Ning Liu, Sayuri Suzuki, Satoki Nakamura, Akira Kikuchi, Masatoshi Kitagawa · 2010 · Cell Division
  76. Dysfunction of microRNA-32 regulates ubiquitin ligase FBXW7 in multiple myeloma disease
    Jingsheng Hua, Tianling Ding, Lin Yang · 2016 · OncoTargets and Therapy
  77. Chronic lymphocytic leukaemia genomics and the precision medicine era
    Hussein Ghamlouch, Florence Nguyen‐Khac, Olivier Bernard · 2017 · British Journal of Haematology
  78. Fbw7γ-mediated degradation of KLF13 prevents RANTES expression in resting human but not murine T lymphocytes
    Dong Seok Kim, Wei Zhang, Scott E. Millman, Byung Joon Hwang, Seok Joo Kwon, Carol Clayberger, Michele Pagano, Alan M. Krensky · 2012 · Blood
  79. Drosophila Minus is required for cell proliferation and influences Cyclin E turnover
    Sébastien Szuplewski, Thomas Sandmann, Ville Hietakangas, Stephen Michael Cohen · 2009 · Genes & Development
  80. Updates in therapy for uterine serous carcinoma
    Dana M. Roque, Alessandro Davide Santin · 2012 · Current Opinion in Obstetrics & Gynecology
  81. Immunophenotypes of Ductal Epithelial Cells in Advanced Pancreatic Ductal Adenocarcinoma
    Rui Zhou, Xiaoxiao Xu, Meizhen Liu, Xinmou Wu, Rong Li · 2018 · Digestion
  82. The E3 Ligases in Cervical Cancer and Endometrial Cancer
    Fengguang Zhai, Jie Wang, Weili Yang, Meng Ye, Xiaofeng Jin · 2022 · Cancers
  83. Krüppel-like Factor-9 and Krüppel-like Factor-13: Highly Related, Multi-Functional, Transcriptional Repressors and Activators of Oncogenesis
    Frank A. Simmen, Iad Alhallak, Rosalia C. M. Simmen · 2023 · Cancers
  84. Biomarkers in lung oncology
    Rafael Rosell, Alain Vergnenégre, Baorui Liu, Manuel Cobo, Bartomeu Massutí, Jia Wei, Miguel Ángel Molina‐Vila, Carlota Costa, Cristina Queralt, Miquel Tarón · 2010 · Pulmonary Pharmacology & Therapeutics
  85. UBE 2 QL 1 is Disrupted by a Constitutional Translocation Associated with Renal Tumor Predisposition and is a Novel Candidate Renal Tumor Suppressor Gene
    Naomi C. Wake, Christopher J. Ricketts, Mark R. Morris, Elena Prigmore, Susan M. Gribble, Anne‐Bine Skytte, Mick D. Brown, Noel William Clarke, Rosamonde Elizabeth Banks, Shirley Victoria Hodgson et al. · 2013 · Human Mutation
  86. Fbxw7 hotspot mutations and human colon cancer: mechanistic insights from new mouse models
    Jonathan E. Grim · 2013 · Gut
  87. Exploration of Synthetic Lethal Interactions as Cancer Drug Targets
    Hendrik J. Kuiken, Roderick L. Beijersbergen · 2010 · Future Oncology
  88. Notch-dependent expression of thearchipelagoubiquitin ligase subunit in theDrosophilaeye
    Sarah C. Nicholson, Brandon Nicolay, Maxim V. Frolov, Kenneth H. Moberg · 2010 · Development
  89. The Multifunctional Nucleolar Protein Nucleophosmin/NPM/B23 and the Nucleoplasmin Family of Proteins
    Shea Ping Yip, Parco M. Siu, Polly H. M. Leung, Yanxiang Zhao, Benjamin Yat‐Ming Yung · 2011 · Springer eBooks
  90. 27-Hydroxycholesterol increases Myc protein stability via suppressing PP2A, SCP1 and FBW7 transcription in MCF-7 breast cancer cells
    Liming Ma, Zirui Liang, Keren Zhou, Hui Zhou, Liang‐Hu Qu · 2016 · Biochemical and Biophysical Research Communications
  91. E3 ubiquitin ligase FBW7α inhibits cholangiocarcinoma cell proliferation by downregulating c-Myc and cyclin E
    Ming Li, Ling Ouyang, Zhigang Zheng, Dan Xiang, Aijun Ti, Leihua Li, Yuzhen Dan, Chundong Yu, Wengang Li · 2017 · Oncology Reports
  92. CK1δ/GSK3β/FBXW7α axis promotes degradation of the ZNF322A oncoprotein to suppress lung cancer progression
    S-Y Liao, C-W Chiang, Chun‐Hua Hsu, Y-T Chen, Jayu Jen, Hsueh‐Fen Juan, W-W Lai, Y-C Wang · 2017 · Oncogene
  93. Structural basis for Cullins and RING component inhibition: Targeting E3 ubiquitin pathway conductors for cancer therapeutics
    Shagufta Shafique, Waqar Ali, Sonia Kanwal, Sajid Rashid · 2017 · International Journal of Biological Macromolecules
  94. NONO ubiquitination is mediated by FBW7 and GSK3 β via a degron lost upon chromosomal rearrangement in cancer
    Luigi Alfano, Antonella Caporaso, Angela Altieri, Caterina Costa, Iris Maria Forte, Carmelina Antonella Iannuzzi, Daniela Barone, Luca Esposito, Antonio Giordano, Francesca Pentimalli · 2017 · Journal of Cellular Physiology
  95. Degradation of the endoplasmic reticulum–anchored transcription factor MyRF by the ubiquitin ligase SCFFbxw7 in a manner dependent on the kinase GSK-3
    Shogo Nakayama, Kanae Yumimoto, Atsuki Kawamura, Keiichi I. Nakayama · 2018 · Journal of Biological Chemistry
  96. Novel role for receptor dimerization in post-translational processing and turnover of the GRα
    Legh Wilkinson, Nicolette J. D. Verhoog, Ann Louw · 2018 · Scientific Reports
  97. A negative feedback loop between XBP1 and Fbw7 regulates cancer development
    Unbin Chae, Heejin Lee, Bokyung Kim, Haiyoung Jung, Byeong Mo Kim, Ann- Hwee Lee, Dong‐Seok Lee, Sang‐Hyun Min · 2019 · Oncogenesis
  98. Regulation of metabolic reprogramming by tumor suppressor genes in pancreatic cancer
    Mengqi Liu, Wensheng Liu, Yi Qin, Xiaowu Xu, Xianjun Yu, Qifeng Zhuo, Shunrong Ji · 2020 · Experimental Hematology and Oncology
  99. Suppressive role of E3 ubiquitin ligase FBW7 in type I diabetes in non-obese diabetic mice through mediation of ubiquitination of EZH2
    Yingxue Guo, Junfeng Li, Shuang Fan, Qibo Hu · 2021 · Cell Death Discovery
  100. SALSA, a genetically encoded biosensor for spatiotemporal quantification of Notch signal transduction in vivo
    Justin M. Shaffer, Iva Greenwald · 2022 · Developmental Cell