Thiopurines in current medical practice: molecular mechanisms and contributions to therapy-related cancer

Cited by (474)

Items 301–400 of 474

1. Visualizing Drug Release from a Stimuli-Responsive Soft Material Based on Amine–Thiol Displacement
   Tianhong Wu, Shiqing Huang, Xing Feng, Xiaogang Liu, Tony D. James, Xiaolong Sun, Xuhong H. Qian · 2023 · ACS Applied Materials & Interfaces
2. Research design, evaluation, and in vitro assessment of N'-(thiophene-2-carbonyl) pyridine-4-carbohydrazide as a biological agent
   Kalidoss Ranganathan, S. Magesh, T. Kamatchi, S. Shreedevi · 2024 · Journal of Molecular Structure
3. A Novel RAGE Modulator Induces Soluble RAGE to Reduce BACE1 Expression in Alzheimer's Disease
   Seung Hyun Baek, Suji Hong, Eunae Kim, Sunyoung Park, Min‐Young Lee, Jinsu Park, Yoonsuk Cho, Hyun-Jun Yoon, Daeseung Kim, Young‐Kwang Yun et al. · 2025 · Advanced Science
4. A Case of Therapy-Related Myeloid Neoplasm in a Patient with Crohn’s Disease Treated with Azathioprine
   François Mullier, Jean‐François Rahier, Francois M. Maignen, Yvan Cornet, Carlos Graux, Christian Chatelain, Bernard Châtelain, Jean‐Michel Dogné · 2012 · Acta Haematologica
5. DNA Mismatch Repair: Dr. Jekyll and Mr. Hyde?
   Peggy Hsieh · 2012 · Molecular Cell
6. Discovery of 6-chloro-2-(propylthio)-8,9-dihydro-7H-purines containing a carboxamide moiety as potential selective anti-lung cancer agents
   Taoqian Zhao, Yuandi Zhao, Xin‐Yang Liu, Bo Wang, Zhonghua Li, Zhangxu He, Xinhui Zhang, Jian-Jia Liang, Liying Ma, Hong‐Min Liu · 2018 · European Journal of Medicinal Chemistry
7. Efforts in redesigning the antileukemic drug 6-thiopurine: decreasing toxic side effects while maintaining efficacy
   Arnaldo X. Torres-Hernandez, Chamitha J. Weeramange, Prathibha Desman, Anthony Fatino, Olivia Haney, Ryan J. Rafferty · 2018 · MedChemComm
8. NUDT15 Genetic Variants in Chinese Han, Uighur, Kirghiz, and Dai Nationalities
   Fang Zhang, Gulbanur Amat, Yanjing Tang, Ru Chen, Xin Tian, Wenting Hu, Changcheng Chen, Shuhong Shen, Yangyang Xie · 2022 · Frontiers in Pediatrics
9. Thioguanine restoration through type I photosensitization-superoxide oxidation-glutathione reduction cycles
   Nelson Euceda, Joyce Jahnke, Aileen Espinal, Monique F. Louis, Edan Bashkin, Patricia Roccanova, Abraham Espaillat, German V. Fuentes, Fernando Nieto, Ruomei Gao · 2021 · Physical Chemistry Chemical Physics
10. Syndrome CMMRD (déficience constitutionnelle des gènes MMR) : bases génétiques et aspects cliniques
    Bruno Buecher, Marine Le Mentec, François Doz, Franck Bourdeaut, Marion Gauthier‐Villars, Dominique Stoppa‐Lyonnet, Chrystelle Colas · 2018 · Bulletin du Cancer
11. No association between relapse hazard and thiopurine methyltransferase geno- or phenotypes in non-high risk acute lymphoblastic leukemia: a NOPHO ALL2008 sub-study
    Stine Nygaard Nielsen, Linea Natalie Toksvang, Kathrine Grell, Jacob Nersting, Jonas Abrahamsson, Bendik Lund, Jukka A. Kanerva, Ólafur Gísli Jónsson, Goda Elizabeta Vaitkevičienė, Kaie Pruunsild et al. · 2021 · Cancer Chemotherapy and Pharmacology
12. Azathioprine-Induced Microsatellite Instability Is Not Observed in Skin Carcinomas of Organ Transplant Recipients
    Hermina C. Wisgerhof, Liesbeth Hameetman, Cornelis P. Tensen, Hans M. Morreau, Johan Willem de Fijter, Jan Nico Bouwes Bavinck, Rein Willemze, Frank R. de Gruijl · 2009 · Journal of Investigative Dermatology
13. The NUDIX hydrolase NUDT5 influences purine nucleotide metabolism and thiopurine pharmacology
    Leo Kager, Kaan Boztuǧ · 2025 · Journal of Clinical Investigation
14. Pharmacogenetics-based personalized treatment in patients with inflammatory bowel disease: A review
    Ji Young Chang, Jae Hee Cheon · 2021 · Precision and Future Medicine
15. Allele-specific polymerase chain reaction can determine the diplotype of NUDT15 variants in patients with childhood acute lymphoblastic Leukemia
    Chih‐Hsiang Yu, Ya-Hsuan Chang, Der-Shiun Wang, Shiann‐Tarng Jou, Chien‐Yu Lin, Kai‐Hsin Lin, Meng‐Yao Lu, Kang‐Hsi Wu, Chao‐Neng Cheng, Hsiu‐Hao Chang et al. · 2023 · Scientific Reports
16. Thiopurines Analogues with Additional Ring: Synthesis, Spectroscopic Properties, and Anticancer Potency
    Katarzyna Krancewicz, Karolina Nowicka-Bauer, Katarzyna Fiedorowicz, Bronisław Marciniak, Katarzyna Taras‐Goślińska · 2023 · International Journal of Molecular Sciences
17. Clinical Actionability of the NUDT15 * 4 (p. R139H ) Allele and Its Association With Hispanic Ethnicity
    Maud Maillard, Jenny Q. Nguyen, Wenjian Yang, Keito Hoshitsuki, Mary V. Relling, Kelly E. Caudle, Kristine R. Crews, Sima Jeha, Hiroto Inaba, Ching‐Hon Pui et al. · 2024 · Clinical Pharmacology & Therapeutics
18. Children with low‐risk acute lymphoblastic leukemia are at highest risk of second cancers
    Stine Nygaard Nielsen, Frank Eriksson, Susanne Rosthøj, Mette Klarskov Andersen, Erik Forestier, Henrik Hasle, Lisa Lyngsie Hjalgrim, Ann Elisabeth Åsberg, Jonas Abrahamsson, Mats Marshall Heyman et al. · 2017 · Pediatric Blood & Cancer
19. Enzymatic Thioamide Formation in a Bacterial Antimetabolite Pathway
    Agnieszka Litomska, Keishi Ishida, Kyle L. Dunbar, Marco Boettger, Sébastien Coyne, Christian Hertweck · 2018 · Angewandte Chemie
20. Influence of the Photodegradation of Azathioprine on DNA and Cells
    Mihaela-Cristina Bunea, Victor C. Diculescu, Monica Enculescu, Daniela Oprea, Teodor Adrian Enache · 2022 · International Journal of Molecular Sciences
21. Enhancing cancer therapy: The potential of mercaptopurine-based nanomaterials for targeted drug delivery
    Mehrab Pourmadadi, Arsalan Rahmani Ghohrodi, Zeinab Savari, Ehsan Talebi, Iman Ahamdi, Abbas Rahdar, Sadanand Pandey · 2023 · Next Nanotechnology
22. Mycobacteria: Leprosy, a Battle Turned; Tuberculosis, a Battle Raging; Paratuberculosis, a Battle Ignored
    Robert J. Greenstein, T. Gillis, David Scollard, Sheldon T. Brown · 2014 · ASM Press eBooks
23. Inflammatory bowel disease and the hygiene hypothesis: an argument for the role of helminths
    David E. Elliott, Joel V. Weinstock · 2009 · Birkhäuser Basel eBooks
24. Surgical Procedure for Sporadic Colorectal Cancer in Patients with Mild Ulcerative Colitis
    Motoi Uchino, Hiroki Ikeuchi, Hiroki Matsuoka, Toshihiro Bando, Akihiro Hirata, Satoru Yasukawa, Yoshio Takesue, Naohiro Tomita · 2012 · Case Reports in Gastroenterology
25. The impact of 6-thioguanine incorporation into DNA on the function of DNA methyltransferase Dnmt3a
    Olga V. Kirsanova, Alexander V. Sergeev, Ivan S. Yasko, Elizaveta S. Gromova · 2017 · Nucleosides Nucleotides & Nucleic Acids
26. Radiation Induced One-Electron Oxidation of 2-Thiouracil in Aqueous Solutions
    Konrad Skotnicki, Katarzyna Taras‐Goślińska, Ireneusz Janik, Krzysztof Bobrowski · 2019 · Molecules
27. NUDT15 polymorphism in healthy children with Bai nationality in Yunnan of China
    Gangling Pu, Yali Wang, Shaoqin Duan, Jingpei Chen, Chunhui Yang, Tingting Cui, Chunlian Fang, Yan Zhou, Han Zhang, Xin Tian · 2020 · Pediatrics International
28. Dynamics of leucocyte DNA thioguanine nucleotide levels during maintenance therapy of childhood acute lymphoblastic leukemia
    R. Larsen, Lisa Lyngsie Hjalgrim, Matilda Degn, Jacob Nersting, Bodil E. Thorhauge Als-Nielsen, Kathrine Grell, Kjeld Schmiegelow · 2021 · Cancer Chemotherapy and Pharmacology
29. PRPS2 mutations drive acute lymphoblastic leukemia relapse through influencing PRPS1/2 hexamer stability
    Lili Song, Peifeng Li, Huiying Sun, Lixia Ding, Jing Wang, Benshang Li, Bin‐Bing S. Zhou, Haizhong Feng, Yanxin Li · 2022 · Blood Science
30. Analyses of the combination of 6-MP and dasatinib in cell culture
    Gurmeet Kaur, Holger Peter Behrsing, Ralph E. Parchment, Myrtle Davis Millin, Beverly A. Teicher · 2013 · International Journal of Oncology
31. Rare gene variants in a patient with azathioprine-induced lethal myelosuppression
    Xiaoxue Yang, Heng Yi Xu, Jun J.J. Yang, Li Yang · 2017 · Annals of Hematology
32. Inhibition of UDP-glucose dehydrogenase by 6-thiopurine and its oxidative metabolites: Possible mechanism for its interaction within the bilirubin excretion pathway and 6TP associated liver toxicity
    Chamitha J. Weeramange, Cassie M. Binns, Chixiang Chen, Ryan J. Rafferty · 2017 · Journal of Pharmaceutical and Biomedical Analysis
33. CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth
    Huynh, Tony, Murray, Jayne, Flemming, Claudia L., Kamili, Alvin, Hofmann, Ute, Cheung, Leanna, Roundhill, Elizabeth A., Yu, Denise M.T., Webber, Hannah T., Schwab, Matthias et al. · 2020 · Biochemical Pharmacology
34. Identification of Rare Defective Allelic Variants in Cases of Thiopurine S-Methyltransferase Deficient Activity
    Albain Chansavang, Sadok Maalej, Céline Narjoz, Marie‐Anne Loriot, Nicolas Pallet · 2020 · Pharmacogenomics
35. Prodrug Strategy Extends the Use of Anti-HIV Sulfanylbenzamides for Application In Vivo
    Marco Robello, Herman Nikolayevskiy, Michael T. Scerba, Rogers Alberto Ñahui Palomino, Vincenzo Mercurio, Daniel H. Appella · 2023 · ACS Pharmacology & Translational Science
36. Mutations in a Membrane Permease or hpt Lead to 6-Thioguanine Resistance in Staphylococcus aureus
    Denny Chin, Mariya I. Goncheva, Ronald S. Flannagan, David E. Heinrichs · 2021 · Antimicrobial Agents and Chemotherapy
37. Specific MRP4 Inhibitor Ceefourin-1 Enhances Apoptosis Induced by 6-Mercaptopurine in Jurkat Leukemic Cells, but Not in Normal Lymphoblast Cell Line CRL-1991
    Edgardo Becerra, Laura C. Berumen, Valeria Soto-Ontiveros, Guadalupe García‐Alcocer · 2022 · Medicina
38. Diffuse large B-cell lymphoma in a patient treated with azathioprine for ulcerative colitis: a case report
    Hari Sedai, Suraj Shrestha, Vikash Chand, Elisha Poddar, Suman Acharya, Dinesh Prasad Koirala · 2023 · Annals of Medicine and Surgery
39. Loss of Nudt15 thiopurine detoxification increases direct DNA damage in hematopoietic stem cells
    Noriaki Yamashita, Masahiro Kawahara, Takayuki Imai, Goichi Tatsumi, Ai Nishishita-Asai, Akira Andoh · 2023 · Scientific Reports
40. Azathioprine‐induced severe myelosuppression accompanied by massive hair loss and painful oral ulcer in an autoimmune hepatitis patient with NUDT15 minor variant: A case report
    Yu Takeuchi, Hidenao Noritake, Moe Matsumoto, Masahiro Umemura, M. Yamashita, Kensuke Kitsugi, Shingo Takatori, Kazuyoshi Ohta, Jun Ito, Shin Shimoyama et al. · 2021 · Clinical Case Reports
41. Interethnic Differences in Drug Response: Projected impact of Genetic Variations in the Saudi Population
    Abdullah Alsultan, Abdullah Abdulaziz Alalwan, Bashayer Alshehri, Majed Al Jeraisy, Jahad Alghamdi, Saeed Alqahtani, Ahmed Abdulrahman Albassam · 2023 · Pharmacogenomics
42. DNA Damage, Repair and Misrepair in Cancer and in Cancer Therapy
    Ana M, Leonardo M. R. Ferreira, F. Joana, Carlos F., C. Maria · 2011 · InTech eBooks
43. Low NUDT15 expression levels due to biallelic NUDT15 variants and 6‐mercaptopurine intolerance
    Masanori Yoshida, Scott A. Brown, Takaya Moriyama, Rina Nishii, Shin‐ichi Tsujimoto, Yuji Yamada, Kaoru Yoshida, Ryota Shirai, Tomoo Osumi, Tomoyuki Utano et al. · 2022 · British Journal of Haematology
44. Ras-Targeting Action of Thiopurines in the Presence of Reactive Nitrogen Species
    Jongyun Heo, Inpyo Hong · 2010 · Biochemistry
45. TPMT polymorphisms and minimal residual disease after 6-mercaptopurine post-remission consolidation therapy of childhood acute lymphoblastic leukaemia
    Karin Dreisig, Emilie Damgaard Brünner, Hanne Vibeke Marquart, Louise Rold Helt, Jacob Nersting, Thomas Leth Frandsen, Ólafur Gísli Jónsson, Mervi H. Taskinen, Goda Elizabeta Vaitkevičienė, Bendik Lund et al. · 2020 · Pediatric Hematology and Oncology
46. On the malignant potential of thiopurine therapy
    Nanne K.H. de Boer, Dirk P. van Asseldonk, Adriaan Anthonie Van Bodegraven · 2009 · Blood
47. Establishment of a novel predictive model for thiopurine-induced leucopenia based on the polymorphisms in the DNA-thioguanine nucleotide metabolite pathway in Chinese patients with inflammatory bowel disease
    Xia Shuang ZHU, Xue-ding Wang, Qiaolan Xuan, Shaoxing Guan, Yan-pin Guan, Xiang Gao, Kang Chao, Min Huang · 2025 · Drug Metabolism and Disposition
48. Pooled overexpression screening identifies PIPPI as a novel microprotein involved in the ER stress response
    Lorenzo Lafranchi, Glancis L. Raja Arul, Alberto M. Arenas, Anna Spinner, Kovi R Shrung, Maximilian Hornisch, Dörte Schlesinger, Carmen Navarro Luzon, Linus Brinkenstråhle, Rui Shao et al. · 2025 · Nucleic Acids Research
49. AFB1‐induced mutagenesis of the gpt gene in AS52 cells
    Roongtiwa Wattanawaraporn, Min Young Kim, Jillian E. Adams, Laura J. Trudel, Leslie L. Woo, Robert G. Croy, John M. Essigmann, Gerald N. Wogan · 2012 · Environmental and Molecular Mutagenesis
50. Cumulative exposure to tacrolimus during early period after liver transplantation does not affect the recurrence of hepatocellular carcinoma
    Deok Gie Kim, Seung Hyuk Yim, Eun‐Ki Min, Mun Chae Choi, Dong Jin Joo, Myoung Soo Kim, Jae Geun Lee · 2023 · Scientific Reports
51. Thiol responsive 6-thioguanine delivery using fluorescent gold nanoconjugate for synergistic oxidative stress amplification and chemotherapy: A combinatorial approach in cancer management
    Namita Jaiswal, Nibedita Mahata, Gautam Biswas, Nripen Chanda · 2024 · Journal of Drug Delivery Science and Technology
52. Harnessing the Excited States of 5-(5-Phenylthiophen-2-yl)-6-Azauridine as a Three-Pronged Agent for Skin Cancer Therapy: Photodynamic Action, Cell Imaging, and Cancer Cell Inhibition
    Sourav Kanti Seth, Chris Acquah, Liraz Levi, Steffen Jockusch, Carlos E. Crespo‐Hernández · 2025 · ACS Applied Bio Materials
53. Impact of different immunosuppressants on the incidence of Pneumocystis jirovecii pneumonia in kidney transplant recipients: a systematic review and meta-analysis
    Huyu Wang, Jing Guo, Chengjun Yu, Jie Zhang, Hanyu Xiao, Sheng Wen, Yajuan Chen, Yi Hua · 2025 · International Urology and Nephrology
54. Dermatology Clinics
    Harleen K. Sidhu, Rita V. Patel, Gary Goldenberg · 2012 · Dermatologic Clinics
55. Treatment-related Myelodysplastic Syndrome in a Child With Acute Myeloid Leukemia and TPMT Heterozygosity
    Lars M. Stensman, Eigil Kjeldsen, Jacob Nersting, Kjeld Schmiegelow, Henrik Hasle · 2014 · Journal of Pediatric Hematology/Oncology
56. Photodegradation of Azathioprine in the Presence of Sodium Thiosulfate
    N’ghaya Toulbe, Ion Smaranda, Catalin Constantin Negrila, Cristina Bartha, Corina-Mihaela Manta, Mihaela A. Baibarac · 2022 · International Journal of Molecular Sciences
57. Excited States of Thio-2′-deoxyuridine Bearing an Extended π-Conjugated System: 3′,5′-Di-O-acetyl-5-phenylethynyl-4-thio-2′-deoxyuridine
    Daiki Nonoshita, Wataru Kashihara, Kazuhito Tanabe, Tasuku Isozaki, Yao−Zhong Xu, Tadashi Suzuki · 2020 · The Journal of Physical Chemistry A
58. Mitigating UVA light induced reactivity of 6-thioguanine through formation of a Ru( ii ) half-sandwich complex
    Raja Mitra, Ashoka G. Samuelson · 2014 · RSC Advances
59. Branched-chain and dendritic lipids for nanoparticles
    Michael W. Meanwell, Connor O’Sullivan, Perry L. Howard, Thomas Murray Fyles · 2016 · Canadian Journal of Chemistry
60. A Recent Achievement in the Discovery and Development of Vaccines and Therapeutic Agents in the Race for COVID-19 Protection and Treatment
    Zemene Demelash Kifle, Engidaw Fentahun Enyew, Abebe Basazn Mekuria · 2021 · Journal of Evidence-Based Integrative Medicine
61. Halogen substituted 4-thio-2′-deoxyuridines as photosensitizers for the photodynamic therapy of prostate cancer. An in vitro study
    Anna Czaja, Magdalena Datta, Janusz Rak, Magdalena Zdrowowicz · 2025 · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy
62. Pro-905, a Novel Purine Antimetabolite, Combines with Glutamine Amidotransferase Inhibition to Suppress Growth of Malignant Peripheral Nerve Sheath Tumor
    Kathryn M. Lemberg, Eunus Sheemul Ali, Marcela Krečmerová, Joanna Marie H. Aguilar, Jesse Alt, Diane E. Peters, Liang Zhao, Ying Wu, Naziba Nuha, John M. Asara et al. · 2023 · Molecular Cancer Therapeutics
63. Identification of an RNA-binding perturbing characteristic for thiopurine drugs and their derivatives to disrupt CELF1–RNA interaction
    Yang Tan, Zhibo Zhao, Qingfang Han, Peipei Xu, Xiaopeng Shen, Yajun Jiang, Qiang Xu, Xingxin Wu · 2024 · Nucleic Acids Research
64. Population Pharmacokinetics Model of Thioguanine in Patients with Inflammatory Bowel Disease
    Ahmed B. Bayoumy, Nanne K.H. de Boer, Ron J. Keizer, Luc J. J. Derijks · 2025 · Clinical Pharmacokinetics
65. EPIDEMIOLOGY OF THERAPY-RELATED MYELOID NEOPLASMS IN THE NORDIC COUNTRIES
    Kjeld Schmiegelow · 2011 · Mediterranean Journal of Hematology and Infectious Diseases
66. Jumping translocation involving chromosome 13q in a patient with Crohn's Disease and inv(16)(p13.1q22)/CBFB-MYH11 acute myeloid leukemia
    Sarah Clarke, Rebecca De Kraa, Hun Sheng Chuah, Katherine J. Creeper, Michael Francis Leahy, Matthew Wright · 2022 · Cancer Genetics
67. An analysis pipeline for understanding 6-thioguanine effects on a mouse tumour genome
    Patricio Yankilevich, Loulieta Nazerai, Shona Caroline Willis, Kjeld Schmiegelow, Daniela De Zio, Morten Nielsen · 2024 · Cancer Immunology Immunotherapy
68. New methods to assess 6-thiopurine toxicity and expanding its therapeutic application to pancreatic cancer via small molecule potentiators
    Chamitha J. Weeramange, Ashabha Lansakara, Johnathan Dallman, Thị Dung Nguyễn, Wasundara Hulangamuwa, Ryan J. Rafferty · 2019 · MedChemComm
69. Pharmacokinetics of 6-Thioguanine and 6-Mercaptopurine Combination Maintenance Therapy of Childhood ALL
    Stine Nygaard Nielsen, Thomas Leth Frandsen, Jacob Nersting, Lisa Lyngsie Hjalgrim, Kjeld Schmiegelow · 2014 · Journal of Pediatric Hematology/Oncology
70. Photorelaxation and Photorepair Processes in Nucleic and Amino Acid Derivatives
    Carlos E. Crespo‐Hernández · 2017 · Molecules
71. Non-Hodgkin’s Lymphoma and Colorectal Carcinoma: Metachronous Occurrence in a Patient With Underlying DNA Mismatch Repair Syndrome
    Zunaira Shaukat, Rabia Muhammad Wali · 2020 · Cureus
72. Synthesis of new conjugates of 6-thiopurine and thioguanine with (S)-glutamic acid
    Angelina A. Telegina, Dmitry А. Gruzdev, Галина Л. Левит, Victor P. Krasnov · 2022 · Russian Chemical Bulletin
73. Autoimmune Hepatitis
    Nora V. Bergasa · 2021 · Springer eBooks
74. Combining Directed Evolution with Machine Learning Enables Accurate Genotype-to-Phenotype Predictions
    Alexander J. Howard, Ellen Youngsoo Rim, Oscar D. Garrett, Yejin Shim, James H. Notwell, Pamela C. Ronald · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
75. NUDT5 regulates the global efficacy of nucleoside analog drugs by coordinating purine synthesis and PRPP allocation
    Nicholas C.K. Valerie, Seher Alam, Femke M. Hormann, Ulf Märtens, Bo Lundgren, Massimiliano Gaetani, Johan Boström, Sean G. Rudd, Per I. Arvidsson, Mikael Altun · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
76. Exploring DNA-6MP interactions to develop a receptor with selective binding properties
    Anna Sołdatowska, Marcin Urbanowicz, Magdalena Urbanowicz, Kamila Sadowska, Dorota G. Pijanowska · 2025 · International Journal of Biological Macromolecules
77. Aligning organ-specific toxicities with formulation strategies: a rational design approach to chemotherapy optimization
    Jiayi Lu, Yang Liu · 2025 · International Journal of Pharmaceutics
78. Placing purines in precision medicine: Targeting a metabolic reliance in KRAS-mutant tumors
    Lamberto De Boni, Sally E. Claridge, Shalini Nath, Kassianne Tofani, Benjamin D. Stein, Eric Park, Sabrina Steiner, Olivier Elemento, Chantal Pauli, Benjamin D. Hopkins · 2026 · iScience
79. [Significance of NUDT15 gene in individualized treatment with 6-mercaptopurine in children with acute lymphoblastic leukemia].
    Jing He, Ling Liu · 2019 · PubMed Central
80. Chronic Myeloid Leukemia in Renal Transplantation Patients in the Era of Tyrosine Kinase Inhibitors: A Case Report and Review of the Literature
    Ahmet Murt, Batuhan Bayram, Umut Yılmaz, Nurhan Seyahi, Ahmet Emre Eşkazan · 2024 · The Nephron journals/Nephron journals
81. The Photodynamics of Thionated Pyrimidine Nucleobases: Using Time-Resolved Photoelectron Spectroscopy to Explore Characteristics of Excited-State Topographies
    Susanne Ullrich · 2024 · Nucleic acids and molecular biology
82. Predicting the Adsorption Behavior of 6-mercaptopurine Anticancer Drug upon Polyoxazoline Nanocarrier: A Theoretical Study
    Leila Rahmanifar, Fatemeh Azarakhshi, Elham Moniri · 2023 · Letters in Organic Chemistry
83. Atypical Intrahepatic Cholestasis of Pregnancy: A Red Herring
    Blake H. Bentley, Alexa E. Cecil, William C. Lippert · 2024 · ACG Case Reports Journal
84. Dentistry pathways of coronaviruses transmission: a review
    Zahra Setayesh-Mehr, Mahdiye Poorsargol · 2021 · VirusDisease
85. Imputability of Azathioprine in the Occurrence of Chronic Myeloid Leukemia in Crohn's Disease: An Exceptional Case Report
    Yosra Zaimi, Chayma Bouksir, Shema Ayadi, Myriam Ayari, Feryal Letaief Ksontini · 2022 · Current Drug Safety
86. Suitability of ZnO Nanocomposite of Copolymer (PPy-PNVK-ZnO) (PPy = Polypyrrole; PNVK = Poly 9-vinyl carbazole) for the Detection of 6-Thioguanine: A DFT Analysis
    Kirtesh Pratap Khare, Rachana Kathal, Neelima Shukla, Reena Srivastava, Anurag Srivastava · 2023 · Asian Journal of Chemistry
87. Constitutional Mismatch Repair Deficiency
    Chrystelle Colas, Laurence Brugières, Katharina Wimmer · 2018 · Springer eBooks
88. Collateral damage of NUDT15 deficiency in cancer provides a cancer pharmacogenetic therapeutic window with thiopurines
    Jacob C. Massey, Joseph Magagnoli, S. Scott Sutton, Phillip Buckhaults, Michael D. Wyatt · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
89. Amino acid-modified graphene as a promising nanocarrier for anticancer drugs hydroxyurea and 6-thioguanine: DFT and MD investigations
    Lala Adetia Marlina, Aulia Sukma Hutama, Saifuddin Aziz, Suci Zulaikha Hildayani, Maula Eka Sriyani, Yanuar Setiadi, Patrik Chandra, Muthia Rahayu Iresha · 2025 · Nano-Structures & Nano-Objects
90. Effect and mechanism of allopurinol in acute lymphoblastic leukemia maintenance therapy: Reducing hepatotoxicity and improving myelosuppression effect via thiopurine methyltransferase inhibition and increased DNA-thioguanine levels
    Yanping Guan, Xiaoli Zhang, Wang Jian, Qiaolan Xuan, Xia Zhu, Ailing Cao, Yiyu Zhang, Jian‐Pei Fang, Xue‐Qun Luo, Zhong Zuo et al. · 2025 · Drug Metabolism and Disposition
91. Allopurinol Add‐on 6‐Mercaptopurine Strategy Improves Efficacy and Reduces Toxicity in Pediatric Patients With Acute Lymphoblastic Leukemia
    Yanping Guan, X. Zhang, Sumyuet Chan, S C Su, Qiaolan Xuan, Ting Yang, Xue‐Qun Luo, Zhong Zuo, Dun‐hua Zhou, Min Huang et al. · 2025 · Clinical Pharmacology & Therapeutics
92. ZNF184 negatively regulates HR repair and predicts poor prognosis in acute lymphoblastic leukemia
    Won Chan Hwang, Hee Young Ju, Kibeom Park, Eun Jung Kwon, Eun Seop Seo, Yuheon Chung, Byung‐Gyu Kim, Kyungjae Myung, Dong Min Lim, Yun Hak Kim et al. · 2026 · Nucleic Acids Research
93. Identification of NUDT15*3 Variant in the Bangladeshi Population using Allele-Specific PCR
    Drishty Badhon Sarker, Md Mahmudul Hasan Akash, Abu Ashfaqur Sajib, Sharif Akhteruzzaman · 2022 · Re GEN Open
94. Characterisation of autophagy induction by the thiopurine drugs azathioprine, mercaptopurine and thioguanine in THP-1 macrophages
    Connan D. Masson, Fern Findlay-Greene, Filipa Henderson Sousa, Paul Henderson, Jennifer A. Fraser, Peter G. Barlow, Craig Stevens · 2024 · Naunyn-Schmiedeberg s Archives of Pharmacology
95. Dynamic control of nucleotide metabolism in physiology and disease
    Dohun Kim, Gerta Hoxhaj · 2026 · Nature Cell Biology
96. SLC15A3-mediated dipeptide metabolism confers antimetabolite resistance in lymphoma via mTORC1 activation
    Haojun Yang, Vincenzo Andrea Zingaro, Kevin Boardman, Ashish Noronha, Ekin Güney, Lingru Xue, Saishma Hoigebazar, Isabelle Liu, Sohit Miglani, Siyu Chen et al. · 2026 · Journal of Clinical Investigation
97. Surgical Treatment for Ulcerative Colitis-Associated Cancer or Dysplasia
    Toshimitsu Araki, Yuji Toiyama, Yoshiki Okita, Koji Tanaka, Yasuhiro Inoue, Keiichi Uchida, Masato Kusunoki · 2015 · Springer eBooks
98. Exploring the mechanisms for the radical induced damage of 6‐thioguanine
    L. Sandhiya, K. Senthilkumar · 2017 · International Journal of Quantum Chemistry
99. Intérêt de la recherche du polymorphisme de la thiopurine méthyltransférase et du dosage des métabolites chez les patients traités par azathioprine
    Vivien Guillotin, Gaël Galli, Jean‐François Viallard · 2018 · La Revue de Médecine Interne
100. Purine Synthesis Inhibitors, 6-thioguanine and Azathioprine: Forgotten Treatment Options in Psoriasis and Psoriatic Arthritis
     Thao U. Nguyen, John Y. M. Koo · 2009 · Psoriasis Forum