The blockade of immune checkpoints in cancer immunotherapy
Pardoll, Drew M.·2012·Nature Reviews Cancer
DOI 10.1038/nrc3239
Cited by (1,121)
Items 201–300 of 1,121
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- Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory CellsDe Simone, Marco, Arrigoni, Alberto, Rossetti, Grazisa, Gruarin, Paola, Ranzani, Valeria, Politano, Claudia, Bonnal, Raoul J.P., Provasi, Elena, Sarnicola, Maria Lucia, Panzeri, Ilaria et al. · 2016 · Immunity
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- PDL1 Regulation by p53 via miR-34Cortez, Maria Angelica, Ivan, Cristina, Valdecanas, David, Wang, Xiaohong, Peltier, Heidi J., Ye, Yuping, Araujo, Luiz, Carbone, David P., Shilo, Konstantin, Giri, Dipak K et al. · 2016 · JNCI: Journal of the National Cancer Institute
- Tumor Immunotherapy Directed at PD-1Antoni Ribas · 2012 · New England Journal of Medicine
- Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cellsKim, KiBem, Skora, Andrew D., Li, Zhaobo, Liu, Qiang, Tam, Ada J., Blosser, Richard L., Diaz, Luis A., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert et al. · 2014 · Proceedings of the National Academy of Sciences
- Non-small-cell lung cancerLizza E.L. Hendriks, Jordi Remón, Corinne Faivre Finn, Marina Chiara Garassino, John Victor Heymach, Keith M. Kerr, Daniel S.W. Tan, Giulia Veronesi, Martin Reck · 2024 · Nature Reviews Disease Primers
- Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR MutationNan Chen, Wenfeng Fang, Jianhua Zhan, Shaodong Hong, Yanna Tang, Shiyang Kang, Yaxiong Zhang, Xiaobo He, Ting Zhou, Tao Qin et al. · 2015 · Journal of Thoracic Oncology
- Programmed Death-1 Blockade With Pembrolizumab in Patients With Classical Hodgkin Lymphoma After Brentuximab Vedotin FailurePhilippe A. Armand, Margaret Ann Shipp, Vincent Ribrag, Jean‐Marie Michot, Pier Luigi Zinzani, John G. Kuruvilla, Ellen Snyder, Alejandro Daniel Ricart, Arun Balakumaran, Shelonitda Rose et al. · 2016 · Journal of Clinical Oncology
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- In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapyArlauckas, Sean P., Garris, Christopher S., Kohler, Rainer H., Kitaoka, Maya, Cuccarese, Michael F., Yang, Katherine S., Miller, Miles A., Carlson, Jonathan C., Freeman, Gordon J., Anthony, Robert M. et al. · 2017 · Science Translational Medicine
- Programmed Death-Ligand 1 Expression and Response to the Anti-Programmed Death 1 Antibody Pembrolizumab in MelanomaDaud, Adil I., Wolchok, Jedd D., Robert, Caroline, Hwu, Wen-Jen, Weber, Jeffrey S., Ribas, Antoni, Hodi, F. Stephen, Joshua, Anthony M., Kefford, Richard, Hersey, Peter et al. · 2016 · Journal of Clinical Oncology
- Nanoscale Metal–Organic Framework Overcomes Hypoxia for Photodynamic Therapy Primed Cancer ImmunotherapyGuangxu Lan, Kaiyuan Ni, Ziwan Xu, Samuel S. Veroneau, Yang Song, Wenbin Lin · 2018 · Journal of the American Chemical Society
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- Immunotherapy in Non–Small Cell Lung Cancer: Facts and HopesDeborah B. Doroshow, Miguel F. Sanmamed, Katherine Hastings, Katerina A. Politi, David L. Rimm, Lieping Chen, Ignacio Melero, Kurt Alex Schalper, Roy S. Herbst · 2019 · Clinical Cancer Research
- Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic InfectionHudson, William H., Gensheimer, Julia, Hashimoto, Masao, Wieland, Andreas, Valanparambil, Rajesh M., Li, Peng, Lin, Jian-Xin, Konieczny, Bogumila T., Im, Se Jin, Freeman, Gordon J. et al. · 2019 · Immunity
- TISCH2: expanded datasets and new tools for single-cell transcriptome analyses of the tumor microenvironmentYa Han, Yuting Wang, Xin Dong, Dongqing Sun, Zhaoyang Liu, Jiali Yue, Haiyun Wang, Taiwen Li, Chenfei Wang · 2022 · Nucleic Acids Research
- Association of Vitiligo With Tumor Response in Patients With Metastatic Melanoma Treated With PembrolizumabHua, Camille, Boussemart, Lise, Mateus, Christine, Routier, Emilie, Boutros, Céline, Cazenave, Hugo, Viollet, Roxane, Thomas, Marina, Roy, Séverine, Benannoune, Naima et al. · 2016 · JAMA Dermatology
- Comprehensive analysis of cancer-associated somatic mutations in class I HLA genesSachet Ashok Shukla, Michael S. Rooney, Mohini Rajasagi, Grace Tiao, Philip M. Dixon, Michael S. Lawrence, Jonathan D. Stevens, William J. Lane, Jamie L. DellaGatta, Scott Steelman et al. · 2015 · Nature Biotechnology
- Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNACoelho, Matthew A., de Carné Trécesson, Sophie, Rana, Sareena, Zecchin, Davide, Moore, Christopher, Molina-Arcas, Miriam, East, Philip, Spencer-Dene, Bradley, Nye, Emma, Barnouin, Karin et al. · 2017 · Immunity
- Stereotactic Radiation Therapy Augments Antigen-Specific PD-1–Mediated Antitumor Immune Responses via Cross-Presentation of Tumor AntigenAndrew B. Sharabi, Christopher J. Nirschl, Christina M. Kochel, Thomas R. Nirschl, Brian J. Francica, Esteban Velarde, Theodore L. DeWeese, Charles G. Drake · 2014 · Cancer Immunology Research
- Immune escape to PD-L1/PD-1 blockade: seven steps to success (or failure)Kim, J.M., Chen, D.S. · 2016 · Annals of Oncology
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- Melanoma Cell-Intrinsic PD-1 Receptor Functions Promote Tumor GrowthSonja Kleffel, Christian Posch, Steven R. Barthel, Hansgeorg Mueller, Christoph Schlapbach, Emmanuella Guenova, Christopher P. Elco, Nayoung Lee, Vikram R. Juneja, Qian Zhan et al. · 2015 · Cell
- Association of PD-L1 overexpression with activating EGFR mutations in surgically resected nonsmall-cell lung cancerKoichi Azuma, Keiichi Ota, Akihiko Kawahara, Satoshi Hattori, Eiji Iwama, Takeshi Harada, Koichiro Matsumoto, Koichi Takayama, Shinzo Takamori, M. Kage et al. · 2014 · Annals of Oncology
- Cancer immunotherapies targeting the PD-1 signaling pathwayYoshiko Iwai, Junzo Hamanishi, Kenji Chamoto, Tasuku Honjo · 2017 · Journal of Biomedical Science
- PD-1–Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck CancerCécile Badoual, Stéphane Hans, Nathalie Merillon, Cordélia Van Ryswick, Patrice Ravel, Nadine Benhamouda, Émeline Levionnois, Mevyn Nizard, Ali Si‐Mohamed, Nicolas Besnier et al. · 2012 · Cancer Research
- Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapyRi‐Yao Yang, Linlin Sun, Ching-Fei Li, Yu-Han Wang, Jun Yao, Hui Li, Meisi Yan, Wei‐Chao Chang, Jung-Mao Hsu, Jong‐Ho Cha et al. · 2021 · Nature Communications
- Evolving synergistic combinations of targeted immunotherapies to combat cancerIgnacio Melero, David M. Berman, Maria Angela Aznar, Alan J. Korman, José Luis Perez‐Gracia, John B.A.G. Haanen · 2015 · Nature reviews. Cancer
- Pembrolizumab monotherapy for previously untreated, PD-L1-positive, metastatic triple-negative breast cancer: cohort B of the phase II KEYNOTE-086 studySylvia Adams, Sherene Loi, Deborah Toppmeyer, David W. Cescon, Michelino De Laurentiis, Rita Nanda, Eric P. Winer, Hirofumi Mukai, Kenji Tamura, Anne Caroline Armstrong et al. · 2018 · Annals of Oncology
- CD8+CD103+ Tumor–Infiltrating Lymphocytes Are Tumor-Specific Tissue-Resident Memory T Cells and a Prognostic Factor for Survival in Lung Cancer PatientsDjenidi, Fayçal, Adam, Julien, Goubar, Aïcha, Durgeau, Aurélie, Meurice, Guillaume, de Montpréville, Vincent, Validire, Pierre, Besse, Benjamin, Mami-Chouaib, Fathia · 2015 · The Journal of Immunology
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- The TCF1-Bcl6 axis counteracts type I interferon to repress exhaustion and maintain T cell stemnessTuoqi Wu, Yun Ji, E. Ashley Moseman, Haifeng C. Xu, Monica Manglani, Martha Kirby, Stacie M. Anderson, Robin Handon, Elizabeth Kenyon, Abdel G. Elkahloun et al. · 2016 · Science Immunology
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- Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1Chia‐Wei Li, Seung‐Oe Lim, Ezra M. Chung, Yongsoo Kim, Andrew H Park, Jun Yao, Jong‐Ho Cha, Weiya Xia, Li-Chuan Chan, Tae‐Wan Kim et al. · 2018 · Cancer Cell
- Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesiclesRicklefs, Franz L., Alayo, Quazim, Krenzlin, Harald, Mahmoud, Ahmad B., Speranza, Maria C., Nakashima, Hiroshi, Hayes, Josie L., Lee, Kyungheon, Balaj, Leonora, Passaro, Carmela et al. · 2018 · Science Advances
- Microglia-mediated T cell infiltration drives neurodegeneration in tauopathyChen, Xiaoying, Firulyova, Maria, Manis, Melissa, Herz, Jasmin, Smirnov, Igor, Aladyeva, Ekaterina, Wang, Chanung, Bao, Xin, Finn, Mary Beth, Hu, Hao et al. · 2023 · Nature
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- Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranosticsWei Tang, Wenpei Fan, Joseph Lau, Liming Deng, Zheyu Shen, Xiaoyuan Shawn Chen · 2019 · Chemical Society Reviews
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- <i>Ex Vivo</i>
Profiling of PD-1 Blockade Using Organotypic Tumor SpheroidsJenkins, Russell W., Aref, Amir R., Lizotte, Patrick H., Ivanova, Elena, Stinson, Susanna, Zhou, Chensheng W., Bowden, Michaela, Deng, Jiehui, Liu, Hongye, Miao, Diana et al. · 2018 · Cancer Discovery
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