The blockade of immune checkpoints in cancer immunotherapy

Pardoll, Drew M.·2012·Nature Reviews Cancer

DOI 10.1038/nrc3239

Cited by (1,122)

Items 801–900 of 1,122

An engineered oncolytic virus expressing PD-L1 inhibitors activates tumor neoantigen-specific T cell responses
Guan Wang, Xi Kang, Katherine S. Chen, Tiffany Jehng, Lindsey E. Jones, Jie Chen, Xue F. Huang, Si–Yi Chen · 2020 · Nature Communications
TIGIT-CD226-PVR axis: advancing immune checkpoint blockade for cancer immunotherapy
Eugene Y. Chiang, Ira Mellman · 2022 · Journal for ImmunoTherapy of Cancer
Immune checkpoint inhibitors: An emerging cause of insulin-dependent diabetes
Kotwal, Anupam, Haddox, Candace, Block, Matthew, Kudva, Yogish C · 2019 · BMJ Open Diabetes Research & Care
Nivolumab in NSCLC: latest evidence and clinical potential
Raghav Sundar, Byoung Chul Cho, Julie Renee Brahmer, Ross Andrew Soo · 2015 · Therapeutic Advances in Medical Oncology
The Role of Neoantigens in Naturally Occurring and Therapeutically Induced Immune Responses to Cancer
Jeffrey P. Ward, Matthew M. Gubin, Robert D. Schreiber · 2016 · Advances in immunology
Combination therapy to checkmate Glioblastoma: clinical challenges and advances
Debarati Ghosh, Saikat Nandi, Sonali Bhattacharjee · 2018 · Clinical and Translational Medicine
Ferrimagnetic Vortex Nanoring-Mediated Mild Magnetic Hyperthermia Imparts Potent Immunological Effect for Treating Cancer Metastasis
Xiaoli Liu, Jianjun Zheng, Wei Yan Sun, Xiao Zhao, Yao Li, Ningqiang Gong, Yanyun Wang, Xiaowei Ma, Tingbin Zhang, Lingyun Zhao et al. · 2019 · ACS Nano
Sortase Enzyme-Mediated Generation of Site-Specifically Conjugated Antibody Drug Conjugates with High In Vitro and In Vivo Potency
Roger R. Beerli, Tamara Hell, Anna S. Merkel, Ulf Grawunder · 2015 · PLoS ONE
IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras–Mutant Lung Cancer
Mauricio S. Caetano, Huiyuan Zhang, Amber M. Cumpian, Lei Gong, Neşe Ünver, Edwin Justin Ostrin, Soudabeh Daliri, Seon Hee Chang, Cesar E. Ochoa, Samir Hanash et al. · 2016 · Cancer Research
Combining Immune Checkpoint Inhibitors With Conventional Cancer Therapy
Yiyi Yan, Anagha Bangalore Kumar, Heidi Diann Finnes, Svetomir N. Markovic, Sean S. Park, Roxana Stefania Dronca, Haidong Dong · 2018 · Frontiers in Immunology
D-mannose facilitates immunotherapy and radiotherapy of triple-negative breast cancer via degradation of PD-L1
Ruonan Zhang, Yajing Yang, Wenjing Dong, Mingen Lin, Jing He, Xinchao Zhang, Tongguan Tian, Yunlong Yang, Kun Chen, Qun‐Ying Lei et al. · 2022 · Proceedings of the National Academy of Sciences
Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysis
M. Duruisseaux, Anna Martínez‐Cardús, María Eréndira Calleja-Cervantes, Sebastián Morán, Manuel Castro de Moura, Verónica Dávalos, David Piñeyro, Montse Sánchez‐Céspedes, Nicolas Girard, Marie Brevet et al. · 2018 · The Lancet Respiratory Medicine
Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology
Isaure Vanmeerbeek, Jenny Sprooten, Dirk De Ruysscher, Sabine Tejpar, Peter Vandenberghe, Jitka Palich Fucikova, Radek Špíšek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi et al. · 2020 · OncoImmunology
Relevance of tumor-infiltrating lymphocytes in breast cancer
Sathana Dushyanthen, Paul A. Beavis, Peter Stephen Savas, Zhi Ling Teo, Chenhao Zhou, Mariam Mansour, Phillip Kevin Darcy, Sherene Loi · 2015 · BMC Medicine
Danger signalling during cancer cell death: origins, plasticity and regulation
Abhishek Dinkarnath Garg, S Martin, Jakub Gołąb, Patrizia Agostinis · 2013 · Cell Death and Differentiation
Genomic and Epigenomic Alterations in Cancer
Balabhadrapatruni V. S. K. Chakravarthi, Saroj Nepal, Sooryanarayana Varambally · 2016 · American Journal Of Pathology
Clinicopathological features of programmed death ligand 1 expression with tumor-infiltrating lymphocyte, mismatch repair, and Epstein–Barr virus status in a large cohort of gastric cancer patients
Akihito Kawazoe, Takeshi Kuwata, Yasutoshi Kuboki, Kohei Shitara, Akiko Kawano Nagatsuma, Masaaki Aizawa, Takayuki Yoshino, Toshihiko Doi, Atsushi Ohtsu, Atsushi Ochiai · 2016 · Gastric Cancer
Gemcitabine reduces MDSCs, tregs and TGFβ-1 while restoring the teff/treg ratio in patients with pancreatic cancer
Emma Eriksson, Jessica Wenthe, Sandra Irenaeus, Angelica Loskog, Gustav Jörgen Ullenhag · 2016 · Journal of Translational Medicine
Immunotherapy with single agent nivolumab for advanced leiomyosarcoma of the uterus: Results of a phase 2 study
Eytan Ben‐Ami, Constance M. Barysauskas, Sarah Solomon, Kadija Tahlil, Rita Malley, Melissa Hohos, Kathleen Polson, Margaret Loucks, Mariano Severgnini, Tara Patel et al. · 2017 · Cancer
Activating Antitumor Immunity and Antimetastatic Effect Through Polydopamine‐Encapsulated Core–Shell Upconversion Nanoparticles
Shuangqian Yan, Xuemei Zeng, Yongan Tang, Bi‐Feng Liu, Yu Wang, Xiaogang Liu · 2019 · Advanced Materials
Microfluidics: A New Tool for Modeling Cancer–Immune Interactions
Boussommier-Calleja, Alexandra, Li, Ran, Chen, Michelle B., Wong, Siew Cheng, Kamm, Roger D. · 2016 · Trends in Cancer
Regulatory T cells trigger effector T cell DNA damage and senescence caused by metabolic competition
Liu, Xia, Mo, Wei, Ye, Jian, Li, Lingyun, Zhang, Yanping, Hsueh, Eddy C., Hoft, Daniel F., Peng, Guangyong · 2018 · Nature Communications
A2aR antagonists: Next generation checkpoint blockade for cancer immunotherapy
Robert D. Leone, Ying-Chun Lo, Jonathan D. Powell · 2015 · Computational and Structural Biotechnology Journal
Immune checkpoint inhibitor‐related hypophysitis and endocrine dysfunction: clinical review
Mamta Joshi, Ben Whitelaw, M.T.P. Palomar, Yin Wu, Paul Carroll · 2016 · Clinical Endocrinology
Immune infiltrates in the breast cancer microenvironment: detection, characterization and clinical implication
Samantha Burugu, Karama Asleh, Torsten O. Nielsen · 2016 · Breast Cancer
Iron Nanoparticles for Low-Power Local Magnetic Hyperthermia in Combination with Immune Checkpoint Blockade for Systemic Antitumor Therapy
Yu Chao, Guobin Chen, Chao Liang, Jun Xu, Ziliang Dong, Xiao Han, Chao Wang, Zhuang Liu · 2019 · Nano Letters
Adoptive T Cell Immunotherapy For Cancer
Karlo Perica, Juan Carlos Varela, Mathias Oelke, Jonathan P. Schneck · 2015 · Rambam Maimonides Medical Journal
RNA-Based Vaccines in Cancer Immunotherapy
Megan Ann McNamara, Smita K. Nair, Eda K. Holl · 2015 · Journal of Immunology Research
Immune checkpoint inhibitors, alone or in combination with chemotherapy, as first-line treatment for advanced non-small cell lung cancer. A systematic review and network meta-analysis
Urania G. Dafni, Zoi Tsourti, Katerina Vervita, Solange Peters · 2019 · Lung Cancer
Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis
Xiaoyong Huang, Pengfei Zhang, Chuanyuan Wei, Rui Peng, Jia‐Cheng Lu, Chao Gao, Jia-Bing Cai, Xuan Yang, Jia Fan, Ai‐Wu Ke et al. · 2020 · Molecular Cancer
Mitigating the toxic effects of anticancer immunotherapy
Tara C. Gangadhar, Robert H. Vonderheide · 2014 · Nature Reviews Clinical Oncology
New opportunities for nanoparticles in cancer immunotherapy
Wooram Park, Young-Jae Heo, Dong Keun Han · 2018 · Biomaterials Research
Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway
Jianqin Lu, Xiangsheng Liu, Yu‐Pei Liao, Xiang Wang, Ayman Ahmed, Wen Jiang, Ying Chao Ji, Huan Meng, André E. Nel · 2018 · ACS Nano · Retracted
Nanoenabled Modulation of Acidic Tumor Microenvironment Reverses Anergy of Infiltrating T Cells and Potentiates Anti-PD‑1 Therapy
Yuxue Zhang, Yangyang Zhao, Jizhou Shen, Xun Sun, Yi Liu, Hang Liu, Yucai Wang, Jun Wang · 2019 · Nano Letters
Electromagnetic Nanomedicines for Combinational Cancer Immunotherapy
Jing Li, Yu Luo, Kanyi Pu · 2020 · Angewandte Chemie International Edition
Metabolic profiles of regulatory T cells and their adaptations to the tumor microenvironment: implications for antitumor immunity
Yuheng Yan, Lan Huang, Yiming Liu, Ming Yi, Qian Chu, Dechao Jiao, Kongming Wu · 2022 · Journal of Hematology & Oncology
Therapeutic opportunities for manipulating TReg cells in autoimmunity and cancer
Harald von Boehmer, Carolin Daniel · 2012 · Nature Reviews Drug Discovery
CD44+ Cells in Head and Neck Squamous Cell Carcinoma Suppress T-Cell–Mediated Immunity by Selective Constitutive and Inducible Expression of PD-L1
Yunqin Lee, June Ho Shin, Michelle R. Longmire, Hua Wang, Holbrook E K Kohrt, Howard Y. Chang, John B. Sunwoo · 2016 · Clinical Cancer Research
Armed Oncolytic Adenovirus–Expressing PD-L1 Mini-Body Enhances Antitumor Effects of Chimeric Antigen Receptor T Cells in Solid Tumors
Kiyonori Tanoue, Amanda Rosewell Shaw, Norihiro Watanabe, Caroline Porter, Bhakti Rana, Stephen M Gottschalk, Malcolm K. Brenner, Masataka Suzuki · 2017 · Cancer Research
Unraveling Triple-Negative Breast Cancer Tumor Microenvironment Heterogeneity: Towards an Optimized Treatment Approach
Yacine Barèche, Laurence Buisseret, Tina Gruosso, Edwina Girard, David Venet, Floriane Dupont, Christine Desmedt, Denis Larsimont, Morag Park, Françoise Rothé et al. · 2019 · JNCI Journal of the National Cancer Institute
Recent advances in noble metal complex based photodynamic therapy
Yanping Wu, Shumeng Li, Yuncong Chen, Weijiang He, Zijian Guo · 2022 · Chemical Science
Entinostat Converts Immune-Resistant Breast and Pancreatic Cancers into Checkpoint-Responsive Tumors by Reprogramming Tumor-Infiltrating MDSCs
Brian J. Christmas, Christine Isabelle Rafie, Alexander C. Hopkins, Blake Scott, Hayley S. Ma, Kayla A. Cruz, Skylar Woolman, Todd D. Armstrong, Roisín M. Connolly, Nilo A. Azad et al. · 2018 · Cancer Immunology Research
Macrophage targeting in cancer
Martha Lopez‐Yrigoyen, Luca Cassetta, Jeffrey W. Pollard · 2020 · Annals of the New York Academy of Sciences
Biological drug and drug delivery-mediated immunotherapy
Qingqing Xiao, Xiaotong Li, Yi Li, Zhenfeng Wu, Chenjie Xu, Zhongjian Chen, Wei He · 2020 · Acta Pharmaceutica Sinica B
Systemic therapy of brain metastases: non–small cell lung cancer, breast cancer, and melanoma
Marc Charles Chamberlain, Christina S. Baik, Vijayakrishna K. Gadi, Shailender Bhatia, Laura Q.M. Chow · 2016 · Neuro-Oncology
The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome
Deborah R. Caswell, Charles Swanton · 2017 · BMC Medicine
Adenovirotherapy Delivering Cytokine and Checkpoint Inhibitor Augments CAR T Cells against Metastatic Head and Neck Cancer
Amanda Rosewell Shaw, Caroline E. Porter, Norihiro Watanabe, Kiyonori Tanoue, Andrew Gregory Sikora, Stephen M Gottschalk, Malcolm K. Brenner, Masataka Suzuki · 2017 · Molecular Therapy
Eight-Color Multiplex Immunohistochemistry for Simultaneous Detection of Multiple Immune Checkpoint Molecules within the Tumor Microenvironment
Mark A.J. Gorris, Altuna Halilović, Katrin Rabold, Anne van Duffelen, Iresha N. Ambepitiya Wickramasinghe, Dagmar I. Verweij, Inge M. N. Wortel, Johannes C. Textor, I. Jolanda M. de Vries, Carl Gustav Figdor · 2017 · The Journal of Immunology
Cancer Stem Cells and Immunosuppressive Microenvironment in Glioma
Qianquan Ma, Wenyong Long, Changsheng Xing, Junjun Chu, Mei Luo, Helen Y. Wang, Qing Liu, Rong‐Fu Wang · 2018 · Frontiers in Immunology
Dual blockade immunotherapy targeting PD-1/PD-L1 and CTLA-4 in lung cancer
Weishi Cheng, Kai Kang, Ailin Zhao, Yijun Wu · 2024 · Journal of Hematology & Oncology
Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice
Mohammad Ariful Islam, Rice Jamie, Emma Reesor, Harshal R. Zope, Wei Tao, Michael Lim, Jianxun Ding, Yunhan Chen, Dike Aduluso, Bruce R. Zetter et al. · 2020 · Biomaterials
Harnessing the potential of CAR-T cell therapy: progress, challenges, and future directions in hematological and solid tumor treatments
Gunjan Dagar, Ashna Gupta, Tariq Masoodi, Sabah Nisar, Maysaloun Merhi, Sheema Hashem, Ravi Chauhan, Manisha Dagar, Sameer Mirza, Puneet Bagga et al. · 2023 · Journal of Translational Medicine
The Evolving Role of CD8+CD28− Immunosenescent T Cells in Cancer Immunology
Huff, Wei X., Kwon, Jae Hyun, Henriquez, Mario, Fetcko, Kaleigh, Dey, Mahua · 2019 · International Journal of Molecular Sciences
Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment
Best, Sarah A., De Souza, David P., Kersbergen, Ariena, Policheni, Antonia N., Dayalan, Saravanan, Tull, Dedreia, Rathi, Vivek, Gray, Daniel H., Ritchie, Matthew E., McConville, Malcolm J. et al. · 2018 · Cell Metabolism
Immune Checkpoint Inhibitors: New Insights and Current Place in Cancer Therapy
Ninh My La-Beck, Gary W. Jean, Cindy Huynh, Saeed K Alzghari, Devin B. Lowe · 2015 · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy
Checkpoint inhibitors in pancreatic cancer
Andreas Henriksen, Anne Dyhl-Polk, Inna Markovna Chen, Dorte Lisbet Nielsen · 2019 · Cancer Treatment Reviews
The ferroptosis and iron-metabolism signature robustly predicts clinical diagnosis, prognosis and immune microenvironment for hepatocellular carcinoma
Bufu Tang, Jinyu Zhu, Jie Li, Kai C. Fan, Yang Gao, Shimiao Cheng, Chunli Kong, Liyun Zheng, Fazong Wu, Qiaoyou Weng et al. · 2020 · Cell Communication and Signaling
Thyroid Immune-related Adverse Events Following Immune Checkpoint Inhibitor Treatment
Christopher Alan Muir, Roderick John Clifton-Bligh, Georgina Venetia Long, Richard A. Scolyer, Serigne Lo, Matteo Salvatore Carlino, Venessa Tsang, Alexander Maxwell Menzies · 2021 · The Journal of Clinical Endocrinology & Metabolism
Molecular and functional imaging in cancer-targeted therapy: current applications and future directions
Jing‐Wen Bai, Si-Qi Qiu, Guo‐Jun Zhang · 2023 · Signal Transduction and Targeted Therapy
Dendritic cell-targeted vaccines — hope or hype?
Wolfgang Kastenmüller, Kathrin Kastenmüller, Christian Kurts, Robert A. Seder · 2014 · Nature reviews. Immunology
Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade
Evan J. Lipson, Victor E. Velculescu, Theresa S. Pritchard, Mark Sausen, Drew M. Pardoll, Suzanne Louise Topalian, Luis Alberto Diaz · 2014 · Journal for ImmunoTherapy of Cancer
Correlation between vitiligo occurrence and clinical benefit in advanced melanoma patients treated with nivolumab: A multi‐institutional retrospective study
Yasuhiro Nakamura, Ryota Tanaka, Yuri Asami, Yukiko Teramoto, Taichi Imamura, Sayuri Sato, Hiroshi Maruyama, Yasuhiro Fujisawa, Taisuke Matsuya, Manabu Fujimoto et al. · 2016 · The Journal of Dermatology
Safety and antitumor activity of the anti–PD-1 antibody pembrolizumab in patients with advanced, PD-L1–positive papillary or follicular thyroid cancer
Janice M. Mehnert, Andréa Varga, Marcia S. Brose, Rahul Raj Aggarwal, Chia‐Chi Lin, Amy Prawira, Filippo de Braud, Kenji Tamura, Toshihiko Doi, Sarina Anne Piha-Paul et al. · 2019 · BMC Cancer
Personalized detection of circling exosomal PD-L1 based on Fe3O4@TiO2 isolation and SERS immunoassay
Yuanfeng Pang, Jinmaio Shi, Xingsheng Yang, Chongwen Wang, Zhiwei Sun, Rui Xiao · 2019 · Biosensors and Bioelectronics
Hostile, Hypoxia–A2-Adenosinergic Tumor Biology as the Next Barrier to Overcome for Tumor Immunologists
Sitkovsky, Michail V., Hatfield, Stephen, Abbott, Robert, Belikoff, Bryan, Lukashev, Dmitriy, Ohta, Akio · 2014 · Cancer Immunology Research
Role of Antigen Spread and Distinctive Characteristics of Immunotherapy in Cancer Treatment
James L. Gulley, Ravi Amrit Madan, Russell Kent Pachynski, Peter Mulders, Nadeem Anwar Sheikh, James B. Trager, Charles G. Drake · 2016 · JNCI Journal of the National Cancer Institute
Regulatory T cells: a potential target in cancer immunotherapy
Kohei Shitara, Hiroyoshi Nishikawa · 2018 · Annals of the New York Academy of Sciences
Imaging of Cancer Immunotherapy: Current Approaches and Future Directions
Mizuki Nishino, Hiroto Hatabu, Frank Stephen Hodi · 2018 · Radiology
Microsatellite instability in Gastric Cancer: Between lights and shadows
Elisabetta Puliga, Simona Corso, Filippo Pietrantonio, Silvia Giordano · 2021 · Cancer Treatment Reviews
Immune Checkpoint Inhibitors
John B.A.G. Haanen, Caroline Robert · 2015 · Progress in tumor research
Evaluation of PD-L1 Expression and Associated Tumor-Infiltrating Lymphocytes in Laryngeal Squamous Cell Carcinoma
Maria Vassilakopoulou, Margaritis Avgeris, Vamsidhar Velcheti, Vassiliki Kotoula, Theodore Rampias, Kyriakos Chatzopoulos, Christos Perisanidis, Christos K. Kontos, Aris Ι. Giotakis, Andreas Scorilas et al. · 2015 · Clinical Cancer Research
Delivery of CRISPR/Cas systems for cancer gene therapy and immunotherapy
Xiangrong Song, Chao Liu, Ning Wang, Hai Huang, Siyan He, Changyang Gong, Yuquan Wei · 2020 · Advanced Drug Delivery Reviews
Endocrine-related adverse conditions in patients receiving immune checkpoint inhibition: an ESE clinical practice guideline
Eystein S. Husebye, Frédéric Castinetti, Sherwin Criseno, Giuseppe Curigliano, Brigitte Decallonne, Maria Fleseriu, Claire Higham, Isabella Lupi, Stavroula Α. Paschou, Miklós Tóth et al. · 2022 · European Journal of Endocrinology
T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy
Robert Sackstein, Tobias Schatton, Steven R. Barthel · 2017 · Laboratory Investigation
Current Perspectives on Nasopharyngeal Carcinoma
Hui Mei Lee, Kazuhide S. Okuda, Fermín Eduardo González, Vyomesh Patel · 2019 · Advances in experimental medicine and biology
A phase 1/2 trial of an immune-modulatory vaccine against IDO/PD-L1 in combination with nivolumab in metastatic melanoma
Julie Westerlin Kjeldsen, Cathrine Lund Lorentzen, Evelina Martinenaite, Eva Ellebæk, Marco Donia, Rikke Boedker Holmstroem, Tobias Wirenfeldt Klausen, Cecilie Oelvang Madsen, Shamaila Munir Ahmed, Stine Emilie Weis-Banke et al. · 2021 · Nature Medicine
An expanded universe of cancer targets
Hahn, William C., Bader, Joel S., Braun, Theodore P., Califano, Andrea, Clemons, Paul A., Druker, Brian J., Ewald, Andrew J., Fu, Haian, Jagu, Subhashini, Kemp, Christopher J. et al. · 2021 · Cell
CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory
Kidani, Yujiro, Nogami, Wataru, Yasumizu, Yoshiaki, Kawashima, Atsunari, Tanaka, Atsushi, Sonoda, Yudai, Tona, Yumi, Nashiki, Kunitaka, Matsumoto, Reimi, Hagiwara, Masaki et al. · 2022 · Proceedings of the National Academy of Sciences
PD-L1 Expression in Human Placentas and Gestational Trophoblastic Diseases
Emanuela F. T. Veras, Robert J. Kurman, Tian‐Li Wang, Ie‐Ming Shih · 2016 · International Journal of Gynecological Pathology
PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer
Magalie Dosset, Thaiz Rivera Vargas, Anaïs Lagrange, Romain Boidot, Frédérique Végran, Aurélie Roussey, Fanny Chalmin, Lucile Dondaine, Catherine Paul, Elodie Lauret Marie Joseph et al. · 2018 · OncoImmunology
CAR T cells for brain tumors: Lessons learned and road ahead
David Akhavan, Darya Alizadeh, Dongrui Wang, Michael R. Weist, Jennifer Kelly Shepphird, Christine E. Brown · 2019 · Immunological Reviews
The prognostic relevance of tumour-infiltrating plasma cells and immunoglobulin kappa C indicates an important role of the humoral immune response in non-small cell lung cancer
Miriam Lohr, Karolina Edlund, Johan Botling, Seddik Hammad, Birte Hellwig, Amnah Othman, Anders Berglund, Mats P. Lambe, Lars Holmberg, Simon Ekman et al. · 2013 · Cancer Letters
Hepatotoxicity of immune checkpoint inhibitors: An evolving picture of risk associated with a vital class of immunotherapy agents
Daniel L. Suzman, Lorraine Cheryl Pelosof, Amy S. Rosenberg, Mark Avigan · 2018 · Liver International
Objective Response Rate Among Patients With Locally Advanced or Metastatic Sarcoma Treated With Talimogene Laherparepvec in Combination With Pembrolizumab
Ciara Marie Kelly, Cristina R. Antonescu, Timothy Geoffrey Bowler, Rodrigo Ramella Munhoz, Ping Chi, Mark Andrew Dickson, Mrinal M. Gounder, Mary Louise Keohan, Sujana Movva, Reena Dholakia et al. · 2020 · JAMA Oncology
Continuous inertial cavitation evokes massive ROS for reinforcing sonodynamic therapy and immunogenic cell death against breast carcinoma
Yifei Yin, Xingwu Jiang, Liping Sun, Hongyan Li, Chunxia Su, Yan Zhang, Guang Xu, Xiaolong Li, Chongke Zhao, Yu Chen et al. · 2020 · Nano Today
The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment
Jason B. Williams, Brendan L. Horton, Yan Zheng, Yukan Duan, Jonathan D. Powell, Thomas Frank Gajewski · 2017 · The Journal of Experimental Medicine
Regulation of PD-L1: Emerging Routes for Targeting Tumor Immune Evasion
Yiting Wang, Huanbin Wang, Han Yao, Chushu Li, Jing‐Yuan Fang, Jie Xu · 2018 · Frontiers in Pharmacology
Advances in drug delivery for post-surgical cancer treatment
Lin‐Lin Bu, Junjie Yan, Zejun Wang, Huitong Ruan, Qian Chen, Vivienne Gunadhi, R. Bryan Bell, Zhen Gu · 2019 · Biomaterials
The M2 macrophage marker CD206 : a novel prognostic indicator for acute myeloid leukemia
Zi‐jun Xu, Yu Gu, Cuizhu Wang, Ye Jin, Xiang‐mei Wen, Ji‐chun Ma, Li‐Juan Tang, Zhen-Wei Mao, Jun Qian, Jiang Lin · 2019 · OncoImmunology
Engineering patient-specific cancer immunotherapies
Scheetz, Lindsay, Park, Kyung Soo, Li, Qiao, Lowenstein, Pedro R., Castro, Maria G., Schwendeman, Anna, Moon, James J. · 2019 · Nature Biomedical Engineering
Trastuzumab upregulates PD-L1 as a potential mechanism of trastuzumab resistance through engagement of immune effector cells and stimulation of IFNγ secretion
Bharat K. R. Chaganty, Songbo Qiu, Anneliese M. M. Gest, Yang Lü, Cristina Ivan, George A. Călin, Louis M. Weiner, Zhen Fan · 2018 · Cancer Letters
Neurologic complications of immune checkpoint inhibitors
Andreas Felix Hottinger · 2016 · Current Opinion in Neurology
Not all immune-checkpoint inhibitors are created equal: Meta-analysis and systematic review of immune-related adverse events in cancer trials
Badi Edmond El Osta, Fangyuan Hu, Reem Ahmed Sadek, Rohini Chintalapally, Shou Ching Tang · 2017 · Critical Reviews in Oncology/Hematology
Immune Evasion in Pancreatic Cancer: From Mechanisms to Therapy
Neus Martínez‐Bosch, Judith Vinaixa, Pilar Navarro · 2018 · Cancers
Drug-Induced Sarcoidosis-Like Reactions
Amit Chopra, Amit Nautiyal, Alexandros Kalkanis, Marc A. Judson · 2018 · CHEST Journal
Combinations of Bevacizumab With Cancer Immunotherapy
Daniel S. Chen, Herbert I. Hurwitz · 2018 · The Cancer Journal
Epidermal Growth Factor Receptor (EGFR) Pathway, Yes-Associated Protein (YAP) and the Regulation of Programmed Death-Ligand 1 (PD-L1) in Non-Small Cell Lung Cancer (NSCLC)
Ping‐Chih Hsu, David M. Jablons, Cheng‐Ta Yang, Liang You · 2019 · International Journal of Molecular Sciences
Precision Management of Advanced Non–Small Cell Lung Cancer
Ching‐Yao Yang, James Chih‐Hsin Yang, Pan‐Chyr Yang · 2020 · Annual Review of Medicine
mRNA Vaccine with Antigen-Specific Checkpoint Blockade Induces an Enhanced Immune Response against Established Melanoma
Wang, Yuhua, Zhang, Lu, Xu, Zhenghong, Miao, Lei, Huang, Leaf · 2018 · Molecular Therapy
Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine
Xiaosong Li, Min Min, Nan Du, Ying Gu, Tomas Hode, Mark F. Naylor, Dianjun Chen, Robert E. Nordquist, Wei R. Chen · 2013 · Clinical and Developmental Immunology