High-throughput functional genomics using CRISPR-Cas9

Cited by (1,000)

Items 501–600 of 1,000

1. A Pipeline for Drug Target Identification and Validation
   Eusebio Manchado, Chun‐Hao Huang, Nilgun Tasdemir, Darjus Felix Tschaharganeh, John Erby Wilkinson, Scott W. Lowe · 2016 · Cold Spring Harbor Symposia on Quantitative Biology
2. A review of virus host factor discovery using CRISPR screening
   Wayne Ren See, Meisam Yousefi, Yaw Shin Ooi · 2024 · mBio
3. A CRISPR-Based Toolbox for Studying T Cell Signal Transduction
   Shen Chi, Arthur Weiss, Haopeng Wang · 2016 · BioMed Research International
4. Novel Biological Approaches for Testing the Contributions of Single DSBs and DSB Clusters to the Biological Effects of High LET Radiation
   Veronika Mladenova, Emil Mladenov, George E. Iliakis · 2016 · Frontiers in Oncology
5. Optical Manipulation of CRISPR/Cas9 Functions: From Ultraviolet to Near-Infrared Light
   Yuxuan Chen, Xiaojie Yan, Ping Yuan · 2020 · ACS Materials Letters
6. Arrayed CRISPR reveals genetic regulators of tau aggregation, autophagy and mitochondria in Alzheimer’s disease model
   Lishu Duan, Mufeng Hu, Joseph A. Tamm, Yelena Y. Grinberg, Fang Shen, Yating Chai, Hualin Simon Xi, Lauren Gibilisco, Brinda Ravikumar, Vivek Gautam et al. · 2021 · Scientific Reports
7. Fluorescent RNA cytosine analogue – an internal probe for detailed structure and dynamics investigations
   Anders Foller Füchtbauer, Søren Preus, Karl Börjesson, Scott A. McPhee, David M.J. Lilley, L. Marcus Wilhelmsson · 2017 · Scientific Reports
8. The evolution of CRISPR/Cas9 and their cousins: hope or hype?
   Kul Bhushan, Anirudha Chattopadhyay, Dharmendra Pratap · 2018 · Biotechnology Letters
9. Insights into neural crest development from studies of avian embryos
   Shashank Gandhi, Marianne E. Bronner-Fraser · 2018 · The International Journal of Developmental Biology
10. CRISPRa-mediated NEAT1 lncRNA upregulation induces formation of intact paraspeckles
    Tomohiro Yamazaki, Chikako Fujikawa, Ayaka Kubota, Akinari Takahashi, Tetsuro Hirose · 2018 · Biochemical and Biophysical Research Communications
11. Revolutionize Genetic Studies and Crop Improvement with High-Throughput and Genome-Scale CRISPR/Cas9 Gene Editing Technology
    Ning Yang, Rongchen Wang, Yunde Zhao · 2017 · Molecular Plant
12. TOB1‑AS1 suppresses non‑small cell lung cancer cell migration and invasion through a ceRNA network
    Wen‑Ji Shangguan, Haitao Liu, Zujun Que, Fangfang Qian, Lingshuang Liu, Jianhui Tian · 2019 · Experimental and Therapeutic Medicine
13. The advancements, challenges, and future implications of the CRISPR/Cas9 system in swine research
    Jinfu Zhang, Emmanuel Mulaya Khazalwa, Hussein Molu Abkallo, Yuan Zhou, Xiongwei Nie, Jinxue Ruan, Changzhi Zhao, Jieru Wang, Jing Xu, Xinyun Li et al. · 2021 · Journal of genetics and genomics/Journal of Genetics and Genomics
14. mCAL: A New Approach for Versatile Multiplex Action of Cas9 Using One sgRNA and Loci Flanked by a Programmed Target Sequence
    Gregory C. Finnigan, Jeremy W. Thorner · 2016 · G3 Genes Genomes Genetics
15. System-level genome editing in microbes
    Bálint Csörgő, Ákos Nyerges, György Pósfai, Tamás Fehér · 2016 · Current Opinion in Microbiology
16. Molecular diagnostics for hereditary hearing loss in children
    Manou Sommen, Wim A. Wuyts, Guy Van Camp · 2017 · Expert Review of Molecular Diagnostics
17. CRISPR editing in biological and biomedical investigation
    Jiaojiao Huang, Yanfang Wang, Jianguo Zhao · 2017 · Journal of Cellular Physiology
18. High-throughput screening in multicellular spheroids for target discovery in the tumor microenvironment
    Blaise Calpe, Werner J. Kovacs · 2020 · Expert Opinion on Drug Discovery
19. The Essential Role of Peptidylarginine Deiminases 2 for Cytokines Secretion, Apoptosis, and Cell Adhesion in Macrophage
    Hui-Chun Yu, Chien‐Hsueh Tung, Kuang‐Yung Huang, Hsien‐Bin Huang, Ming‐Chi Lu · 2020 · International Journal of Molecular Sciences
20. Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning
    Elyas Mohammadi, Rui Benfeitas, Hasan Türkez, Jan Borén, Jens Nielsen, Mathias Uhlén, Adil Mardinoğlu · 2020 · Cancers
21. CRISPR/Cas System: An Introduction
    Nayla Munawar, Aftab Ahmad · 2021 · Springer eBooks
22. Active Delivery of CRISPR System Using Targetable or Controllable Nanocarriers
    Yan Lyu, Cheng Yang, Xiaomei Lyu, Kanyi Pu · 2021 · Small
23. Genome-scale targeted mutagenesis in Brassica napus using a pooled CRISPR library
    Jianjie He, Kai Zhang, Shuxiang Yan, Mi Tang, Weixian Zhou, Yongtai Yin, Kang Chen, Chunyu Zhang, Maoteng Li · 2023 · Genome Research
24. Drugging the methylome: DNA methylation and memory
    Andrew John Kennedy, J. David Sweatt · 2016 · Critical Reviews in Biochemistry and Molecular Biology
25. Glial cells as drug targets: What does it take?
    Thomas Möller, H. W. G. M. Boddeke · 2016 · Glia
26. Synthetic Biology Speeds Up Drug Target Discovery
    Yixuan Xie, Yan-Fang Yang, Yu He, Xixi Wang, Peng Zhang, Haocheng Li, Shufang Liang · 2020 · Frontiers in Pharmacology
27. The Impact of CRISPR-Cas9 on Age-related Disorders: From Pathology to Therapy
    Allen Caobi, Rajib Kumar Dutta, Luis D. Garbinski, María Esteban-López, Yasemin Ceyhan, Mickensone Andre, Marko Manevski, Chet Raj Ojha, Jessica Lapierre, Sneham Tiwari et al. · 2020 · Aging and Disease
28. Functional Genomics in Pancreatic β Cells: Recent Advances in Gene Deletion and Genome Editing Technologies for Diabetes Research
    Ming Hu, Ines Cherkaoui, Shivani Misra, Guy A. Rutter · 2020 · Frontiers in Endocrinology
29. The Tetraspanin CD81 Is a Host Factor for Chikungunya Virus Replication
    Lisa Laßwitz, Francisco José Zapatero Belinchón, Rebecca A. Moeller, Kirsten Hülskötter, Timothée Laurent, Lars A. Carlson, Christine Goffinet, Graham Simmons, Wolfgang Baumgärtner, Gisa Gerold · 2022 · mBio
30. High-content CRISPR screening in tumor immunology
    Erin A. Holcomb, Ashley N. Pearson, Kassidy Mikala Jungles, Akshay Tate, Jadyn G. James, Long Jiang, Amanda K. Huber, Michael D. Green · 2022 · Frontiers in Immunology
31. Accelerated genome engineering through multiplexing
    Zehua Bao, Ryan E. Cobb, Huimin Zhao · 2015 · WIREs Systems Biology and Medicine
32. Experimental Strategies to Explore Drug Action and Resistance in Kinetoplastid Parasites
    Magali Van den Kerkhof, Yann G.‐J. Sterckx, Philippe Leprohon, Louis J.R.M. Maes, Guy Caljon · 2020 · Microorganisms
33. Advances in genomics of cashew tree: molecular tools and strategies for accelerated breeding
    Siddanna Savadi, Bommanahalli Munivenkate Gowda Muralidhara, P. Preethi · 2020 · Tree Genetics & Genomes
34. Murine trophoblast organoids as a model for trophoblast development and CRISPR-Cas9 screening
    Qian Mao, Qinying Ye, Yiwen Xu, Jingwei Jiang, Yunhao Fan, Lili Zhuang, Guohui Liu, Tengfei Wang, Zhenwu Zhang, Teng Feng et al. · 2023 · Developmental Cell
35. Genome-scale exon perturbation screens uncover exons critical for cell fitness
    Mei‐Sheng Xiao, Arun Prasath Damodaran, Bandana Kumari, Ethan Dickson, Kun Xing, Tyler A. On, Nikhil Parab, Helen E. King, Alexendar R. Perez, Wilfried M. Guiblet et al. · 2024 · Molecular Cell
36. Regulation of polyubiquitin genes to meet cellular ubiquitin requirement
    Seung-Woo Han, Byung-Kwon Jung, Kwon‐Yul Ryu · 2021 · BMB Reports
37. New insights on CRISPR/Cas9-based therapy for breast Cancer
    Hussein Sabit, Shaimaa E. Abdel-Ghany, Hüseyin Tombuloğlu, Emre Çevik, Amany I. Alqosaibi, Fatma A. Al-Mulhim, Afnan Al Muhanna · 2021 · Genes and Environment
38. Evaluating the cleavage efficacy of CRISPR-Cas9 sgRNAs targeting ineffective regions of Arabidopsis thaliana genome
    Afsheen Malik, Alvina Gul, Faiza Munir, Rabia Amir, Hadi Alipour, Mustafeez Mujtaba Babar, Syeda Marriam Bakhtiar, Rehan Zafar Paracha, Zoya Khalid, Muhammad Qasim Hayat · 2021 · PeerJ
39. Progress and Prospects of Gene Editing in Pluripotent Stem Cells
    Zhenwu Zhang, Xinyu Bao, Chao‐Po Lin · 2023 · Biomedicines
40. Human TMC1 and TMC2 are mechanically gated ion channels
    Songdi Fu, Xueqi Pan, Mingshun Lu, Jianying Dong, Zhiqiang Yan · 2024 · Neuron
41. Phenotypic screening with primary neurons to identify drug targets for regeneration and degeneration
    Daniel J. Cooper, Giulia Zunino, John L. Bixby, Vance Lemmon · 2016 · Molecular and Cellular Neuroscience
42. Modeling of Autism Using Organoid Technology
    Hwan Geun Choi, Juhyun Song, Gui‐Yeon Park, Jongpil Kim · 2016 · Molecular Neurobiology
43. CRISPR Editing Technology in Biological and Biomedical Investigation
    Martyn K. White, Rafal Kaminski, Won‐Bin Young, Pamela Carol Roehm, Kamel Khalili · 2017 · Journal of Cellular Biochemistry
44. Brave new epigenomes: the dawn of epigenetic engineering
    Anna Köferle, Stefan H. Stricker, Stephan Beck · 2015 · Genome Medicine
45. CRISPR/Cas9 genome editing in human pluripotent stem cells: Harnessing human genetics in a dish
    Federico Gonzãlez · 2016 · Developmental Dynamics
46. Efficient CRISPR/Cas9‐Mediated Mutagenesis in Primary Murine T Lymphocytes
    Bonnie Huang, Kristoffer Haurum Johansen, Pamela L. Schwartzberg · 2018 · Current Protocols in Immunology
47. Identifying Circular RNA and Predicting Its Regulatory Interactions by Machine Learning
    Guishan Zhang, Yiyun Deng, Qingyu Liu, Bingxu Ye, Zhiming Dai, Yaowen Chen, Xianhua Dai · 2020 · Frontiers in Genetics
48. Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening
    Michael Aregger, Kun Xing, Thomas Gonatopoulos-Pournatzis · 2021 · Nature Protocols
49. A Simplified Method for CRISPR-Cas9 Engineering of Bacillus subtilis
    Ankita J. Sachla, Alexander J. Alfonso, John D. Helmann · 2021 · Microbiology Spectrum
50. The application of genome-wide CRISPR-Cas9 screens to dissect the molecular mechanisms of toxins
    Bei Wang, Jun-zhu Chen, Xue‐Qun Luo, Guohui Wan, Yan‐Lai Tang, Qiao‐Ping Wang · 2022 · Computational and Structural Biotechnology Journal
51. Genome-wide in vivo CRISPR screen identifies TGFβ3 as actionable biomarker of palbociclib resistance in triple negative breast cancer
    Sophie Poulet, Meiou Dai, Ni Wang, Gang Yan, Julien Boudreault, Girija Daliah, Alan Guillevin, Huong Nguyen, Soaad Galal, Suhad Ali et al. · 2024 · Molecular Cancer
52. When is it MODY? Challenges in the Interpretation of Sequence Variants in MODY Genes
    Sara Althari, Anna L. Gloyn · 2015 · The Review of Diabetic Studies
53. Discovering metabolic disease gene interactions by correlated effects on cellular morphology
    Yang Jiao, Umer Ahmed, M. F. Michelle Sim, Andrea Bejar, Xiaolan Zhang, Mesbah Talukder, Robert Rice, Jason A. Flannick, Anna Podgornaia, Dermot F. Reilly et al. · 2019 · Molecular Metabolism
54. Liver Cancer Gene Discovery Using Gene Targeting, Sleeping Beauty, and CRISPR/Cas9
    Julia E. Kieckhaefer, Flavio Maina, Rebecca G. Wells, Kirk J. Wangensteen · 2019 · Seminars in Liver Disease
55. Secretome-Based Screening in Target Discovery
    Mei Ding, Hanna Tegel, Åsa Sivertsson, Sophia Hober, Arjan Snijder, Mats Ormö, Per-Erik Strömstedt, Rick Davies, Lovisa Holmberg Schiavone · 2020 · SLAS DISCOVERY
56. A comprehensive overview of CRISPR/Cas 9 technology and application thereof in drug discovery
    Amit Khurana, Nilofer Sayed, Vishakha Singh, Isha Khurana, Prince Allawadhi, Pushkar Singh Rawat, Umashanker Navik, Sravan Kumar Pasumarthi, Kala Kumar Bharani, Ralf Weiskirchen · 2022 · Journal of Cellular Biochemistry
57. Comprehensive discovery and functional characterization of the noncanonical proteome
    Chengyu Shi, Fangzhou Liu, Xinwan Su, Zuozhen Yang, Ying Wang, Shanshan Xie, Shaofang Xie, Qiang Sun, Yu Chen, Lingjie Sang et al. · 2025 · Cell Research
58. Unraveling the future of genomics: CRISPR, single-cell omics, and the applications in cancer and immunology
    A Vipin Menon, Bicna Song, Lumen Chao, Diksha Sriram, Pamela A. Chansky, Ishnoor Bakshi, Jane Ulianova, Wei Li · 2025 · Frontiers in Genome Editing
59. In silico biological discovery with large perturbation models
    Djordje Miladinovic, Tobias Höppe, Mathieu Chevalley, Andreas Georgiou, Lachlan Stuart, Arash Mehrjou, Marcus Bantscheff, Bernhard Schölkopf, Patrick Schwab · 2025 · Nature Computational Science
60. Cellular and Molecular Mechanisms of Oxidative DNA Damage and Repair
    Adnan Ayna, Cüneyt Çağlayan, Seyithan Tayşi · 2025 · Medicina
61. The World of Stable Ribonucleoproteins and Its Mapping With Grad-Seq and Related Approaches
    Milan Gerovac, Jörg Vogel, Alexandre Smirnov · 2021 · Frontiers in Molecular Biosciences
62. CRISPR/Cas9 disruption of glucan synthase in Nannochloropsis gaditana attenuates accumulation of β-1,3-glucose oligomers
    Brian W. Vogler, Amy Ashford, Matthew C. Posewitz · 2021 · Algal Research
63. CRISPR-Based Approaches for the High-Throughput Characterization of Long Non-Coding RNAs
    Joshua M. Hazan, Assaf C. Bester · 2021 · Non-Coding RNA
64. Active Intracellular Delivery of a Cas9/sgRNA Complex Using Ultrasound‐Propelled Nanomotors
    Malthe Hansen‐Bruhn, Berta Esteban‐Fernández de Ávila, Mara Beltrán‐Gastélum, Jing Tai Zhao, Doris E. Ramírez‐Herrera, Pavimol Angsantikul, Kurt V. Gothelf, Liangfang Zhang, Joseph Wang · 2018 · Angewandte Chemie
65. Engineered tracrRNA for enabling versatile CRISPR-dCas9-based biosensing concepts
    Saba Safdar, Seppe Driesen, Karen Leirs, Delphine De Sutter, Sven Eyckerman, Jeroen Lammertyn, Dragana Spasić · 2022 · Biosensors and Bioelectronics
66. Genome-wide CRISPR/Cas9 screening for drug resistance in tumors
    Zhongyan Zhang, Hailiang Wang, Qian Yan, Jinwei Cui, Yubin Chen, Shiye Ruan, Jiayu Yang, Zelong Wu, Mingqian Han, Shanzhou� Huang et al. · 2023 · Frontiers in Pharmacology
67. Massively parallel disruption of enhancers active in human neural stem cells
    Evan T. Geller, Mark A. Noble, Matheo Morales, Jake Gockley, Deena Emera, Severin Uebbing, Justin L. Cotney, James P. Noonan · 2024 · Cell Reports
68. Pooled Tagging and Hydrophobic Targeting of Endogenous Proteins for Unbiased Mapping of Unfolded Protein Responses
    Stephanie E. Sansbury, Yevgeniy V. Serebrenik, Tomer Lapidot, David Geoffrey Smith, George M. Burslem, Ophir Shalem · 2023 · Molecular Cell
69. Comparison of genome engineering using the CRISPR-Cas9 system in C. glabrata wild-type and lig4 strains
    Yuke Cen, Bea Timmermans, Ben Souffriau, Johan M. Thevelein, Patrick Van Dijck · 2017 · Fungal Genetics and Biology
70. Optimized guide RNA structure for genome editing via Cas9
    Jianyong Xu, Wei Lian, Yuning Jia, Lingyun Li, Zhong Wei Huang · 2017 · Oncotarget
71. Increased cocaine self‐administration in rats lacking the serotonin transporter: a role for glutamatergic signaling in the habenula
    Lucia Caffino, Michel M. M. Verheij, Lin Que, Chao Ciu-Gwok Guo, Judith Regina Homberg, Fabio Fumagalli · 2018 · Addiction Biology
72. Current advances in haploid stem cells
    Tongtong Cui, Zhikun Li, Qi Zhou, Wei Li · 2019 · Protein & Cell
73. Simple, fast and efficient iTOP-mediated delivery of CRISPR/Cas9 RNP in difficult-to-transduce human cells including primary T cells
    Waleed M. Kholosy, Marieke Visscher, Kim Ogink, Helen Buttstedt, Kelli Griffin, Axel Beier, Jan P. Gerlach, Jan J. Molenaar, Niels Geijsen, Marco de Boer et al. · 2021 · Journal of Biotechnology
74. Applications of CRISPR Technologies in Forestry and Molecular Wood Biotechnology
    Hieu X. Cao, David Michels, Giang T. H. Vu, Oliver Gailing · 2024 · International Journal of Molecular Sciences
75. Genome editing in pluripotent stem cells: research and therapeutic applications
    Michela Deleidi, Cong Yu · 2016 · Biochemical and Biophysical Research Communications
76. In Search of Molecular Markers for Cerebellar Neurons
    Wing Yip Tam, Xia Wang, Andy S. K. Cheng, Kwok‐Kuen Cheung · 2021 · International Journal of Molecular Sciences
77. Decoding Neuronal Diversification by Multiplexed Single-cell RNA-Seq
    Joachim Luginbühl, Tsukasa Kouno, Rei Nakano, Thomas Edward Chater, Divya Mundackal Sivaraman, Mami Kishima, Filip Roudnicky, Piero Carninci, Charles Plessy, Jay W. Shin · 2021 · Stem Cell Reports
78. Engineering Prokaryote Synthetic Biology Biosensors
    Xinyi Wan, Trevor Y. H. Ho, Baojun Wang · 2021 · Springer eBooks
79. Progress and challenges in applying CRISPR/Cas techniques to the genome editing of trees
    Solme Pak, Chenghao Li · 2022 · Forestry Research
80. The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive‐strand RNA viruses
    Boris Bonaventure, Antoine Rebendenne, Ana Luiza Chaves Valadão, Mary Arnaud‐Arnould, Ségolène Gracias, Francisco García-de-Gracia, Joe McKellar, Emmanuel Labaronne, Marine Tauziet, Valérie Vivet‐Boudou et al. · 2022 · EMBO Reports
81. Establishment of a CRISPR/Cas9-Mediated Efficient Knockout System of Trichoderma hamatum T21 and Pigment Synthesis PKS Gene Knockout
    Ning Luo, Zeyu Li, Jian Ling, Jianlong Zhao, Yan Li, Yuhong Yang, Zhenchuan Mao, Bingyan Xie, Huixia Li, Yang Jiao · 2023 · Journal of Fungi
82. Alternative for natural sweeteners: Improving the use of stevia as a source of steviol glycosides
    Marcos Vinícius Silva de Andrade, Simone Ribeiro Lucho, Renato Delmondez de Castro, paulo roberto R. ribeiro · 2023 · Industrial Crops and Products
83. CRISPR-Cas and CRISPR-based screening system for precise gene editing and targeted cancer therapy
    Mingming Qin, Chunhao Deng, Liewei Wen, Guoqun Luo, Ya Meng · 2024 · Journal of Translational Medicine
84. Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells
    Moritz Horn, Virginia Kroef, Kira Allmeroth, Nicole Schuller, Stephan Miethe, Martin Peifer, Josef Martin Penninger, Ulrich Elling, Martin Sebastian Denzel · 2018 · Oncotarget
85. Zebrafish prdm12b acts independently of nkx6.1 repression to promote eng1b expression in the neural tube p1 domain
    Ozge Yildiz, Gerald B. Downes, Charles G. Sagerström · 2019 · Neural Development
86. Interplay between HMGA and TP53 in cell cycle control along tumor progression
    Nathalia Meireles Da Costa, Antônio Palumbo, Marco De Martino, Alfredo Fusco, Luís Felipe Ribeiro Pinto, Luiz Eurico Nasciutti · 2020 · Cellular and Molecular Life Sciences
87. Role of Antimicrobial Drug in the Development of Potential Therapeutics
    Shilpa Borehalli Mayegowda, Manjula Nagalapur Gadilingappa, Saad Ali Alghamdi, Banan Atwah, Zain Alhindi, Fahadul Islam · 2022 · Evidence-based Complementary and Alternative Medicine
88. Genome-Wide CRISPR-Cas9 Screen Reveals the Importance of the Heparan Sulfate Pathway and the Conserved Oligomeric Golgi Complex for Synthetic Double-Stranded RNA Uptake and Sindbis Virus Infection
    Olivier Petitjean, Erika Girardi, Richard Patryk Ngondo, Vladimir V. Lupashin, Sébastien Pfeffer · 2020 · mSphere
89. Novel immunotherapy for gastric cancer: targeting the CD47–SIRPα axis
    Akira Ooki, Hiroki Osumi, Keitaro Shimozaki, Kensei Yamaguchi · 2025 · Cancer and Metastasis Reviews
90. Multi-omics: a bridge connecting genotype and phenotype for epilepsy?
    Nannan Wang, Fei Cao, Lin-Han Zhang, Yi-Fei Zheng, Da Xu · 2025 · Biomarker Research
91. Analysis framework and experimental design for evaluating synergy-driving gene expression
    Nadine Schrode, Carina Seah, P. J. Michael Deans, Gabriel E. Hoffman, Kristen Brennand · 2021 · Nature Protocols
92. Phenylboronic acid-functionalized polyaminoglycoside as an effective CRISPR/Cas9 delivery system
    Meiyu Shao, Yu Qi, Dandan Sui, Fu‐Jian Xu · 2021 · Biomaterials Science
93. Research progress and application of the CRISPR/Cas9 gene-editing technology based on hepatocellular carcinoma
    Shijing Yu, Ruirui Zhao, Bingchen Zhang, Chunmei Lai, Linyan Li, Jiangwen Shen, Xiarong Tan, Jingwei Shao · 2023 · Asian Journal of Pharmaceutical Sciences
94. Unbiased interrogation of functional lysine residues in human proteome
    Ying Bao, Qian Pan, Ping Xu, Zhiheng Liu, Zhixuan Zhang, Yongshuo Liu, Yiyuan Xu, Ying Yu, Zhuo Long Zhou, Wensheng Wei · 2023 · Molecular Cell
95. Solving Puzzles With Missing Pieces: The Power of Systems Biology
    James T. Yurkovich, Bernhard Ørn Palsson · 2015 · Proceedings of the IEEE
96. Flexible CRISPR library construction using parallel oligonucleotide retrieval
    Abigail Read, Shaojian Gao, Eric Batchelor, Ji Luo · 2017 · Nucleic Acids Research
97. Essential genes shape cancer genomes through linear limitation of homozygous deletions
    Maroulio Pertesi, Ludvig Ekdahl, Angelica A. Palm, Ellinor Johnsson, Linnea Järvstråt, Anna-Karin Wihlborg, Björn Nilsson · 2019 · Communications Biology
98. A Genome-Wide CRISPR/Cas9 Screen Reveals the Requirement of Host Sphingomyelin Synthase 1 for Infection with Pseudorabies Virus Mutant gD–Pass
    Julia E. Hölper, Finn E. Grey, John Kenneth Baillie, Tim W. Regan, Nick Parkinson, Dirk W. Höper, Thiprampai Thamamongood, Martin Schwemmle, Katrin Pannhorst, Lisa Wendt et al. · 2021 · Viruses
99. Targeting cellular senescence to combat cancer and ageing
    Chen Wang, Xue Hao, Rugang Zhang · 2022 · Molecular Oncology
100. Genomic Amplifications Cause False Positives in CRISPR Screens
     Ankur Sheel, Wen Xue · 2016 · Cancer Discovery