High-throughput functional genomics using CRISPR-Cas9

Untitled work

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Too Much Compromise in Today's CRISPR Pipelines

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Organelle-selective click labeling coupled with flow cytometry allows high-throughput CRISPR screening of genes involved in phosphatidylcholine metabolismPreprint

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Cutting-edge technologies in neural regeneration

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Genome editing of Spp1 by inhalable CRISPR/Cas9 formulation for treating pulmonary fibrosis

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Single‐Cell CRISPR: An Efficient Strategy for Decoding Plant Cis ‐Regulatory Complexity

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Knockout of CLTC gene reduces but not completely block SFTSV infection

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Targeting Wnt signalling through LINC02418: insights from CRISPR screens

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Regenerating the Senses: Stem Cell‐Derived Sensory Neurons and Functional Genomics in Neurological Disorders

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Carrot genome editing using CRISPR-based systems

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Mutagenomics for Functional Analysis of Plant Genome using CRISPR Library Screen

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Highly Efficient A-to-G Editing in PFFs via Multiple ABEs

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Navigable Genome Engineering: Stepwise Correlation for Precision-Guided Optimization of Microbial Cell Factory Phenotypes

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Cellular Thermal Shift Analysis for Interrogation of CRISPR-Assisted Proteomic Changes

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Responsive Cells for rhEGF bioassay Obtained through Screening of a CRISPR/Cas9 Library

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A CRISPR Screen Identifies Myc-associated Zinc Finger Protein (MAZ) as an Insulator Functioning at CTCF boundaries in Hox ClustersPreprint

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Detecting and Annotating Rare Variants

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Harnessing AI-Driven CRISPR Bioinformatics: Transforming precision diagnostics for antimicrobial resistance and chemical pathology

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KDM6B inhibition enhances chemotherapeutic response in small cell lung cancer via epigenetic regulation of apoptosis and ferroptosis

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A Comprehensive Review on CRISPR-Based Screening and Its Applications

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Versatile electroporation protocols enable reproducible CRISPR-RNP delivery across multiple primary mouse cells of the hematopoietic lineage

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Bridging oxidative post-translational modifications to biological meaning

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Simulation of CRISPR/Cas9-mediated gene editing for the Vitellogenin gene in Apis mellifera

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Antibody-drug conjugates against multidrug-resistant cancers: Biomarker-guided patient selection, payload engineering, linker chemistry, and bystander effects

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Protocol for genome-wide CRISPR knockout screens of bacterial cytotoxins in HeLa cells

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Off-Target Effects of Crop Genome Editing and Its Minimization

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CRISPR applications in medicinal and aromatic plants

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Parallel Convolutional Contrastive Learning Method for Enzyme Function Prediction

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CRISPR-Mediated Library Screening of Gene-Knockout Cell Lines for Investigating Antiviral Innate Immunity

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DSCI: a database of synthetic biology components for innate immunity and cell engineering decision-making processes

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Systematic Comparison of CRISPR and shRNA Screens to Identify Essential Genes Using a Graph-Based Unsupervised Learning Model

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Advanced High Throughput Screening Platforms in Drug Discovery

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Genome-wide screening in human embryonic stem cells identifies genes and pathways involved in the p53 pathway

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The End of Snoring? Application of CRISPR/Cas9 Genome Editing for Sleep Disorders

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Pulling the genome in opposite directions to dissect gene networks

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Systems Approaches to Unravel T Cell Function and Therapeutic Potential in Autoimmune Disease

Salinas, V. H., & Stüve, O. (2021) · The Journal of Immunology · doi:10.4049/jimmunol.2000954 · Cited by 2

Synaptogenesis in the adult CNS—olfactory system

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Use of CRISPR in Infection Control

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NBBt-test: a versatile method for differential analysis of multiple types of RNA-seq data

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Gene Therapy for Human Diseases: Recent Achievements and Near-Term Development Prospects

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Cancer immunotherapy via nucleic acid aptamers

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Applying CRISPR-Cas9 Genome Editing to Study Genes Involved in Peroxisome Biogenesis or Peroxisomal Functions

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Exploring the Use of Alternative Promoters for Enhanced Transgene and sgRNA Expression in Atlantic Salmon Cells

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Exploring retinal degenerative diseases through CRISPR-based screening

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Modulating gene expression as a strategy to investigate thyroid cancer biology

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Identifying and Targeting Key Driver Genes for Collagen Production within the 11q13/14 Breast Cancer Amplicon

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Direct mRNA-to-sgRNA conversion generates design-free ultra-dense CRISPRi libraries for systematic phenotypic screening

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Identifying TP53RK as a key regulator of colorectal cancer survival and a potential therapeutic target

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An Introduction to Genome Editing Techniques

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Application of CRISPR/Cas system in optimizing nutrients and anti-nutrients content in fruits

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RNA-Based dCas9–VP64 System Improves the Viability of Cryopreserved Mammalian Cells

Hu, Y., Li, L., Yin, Y., Huang, H., Uygun, B. E., & Yarmush, M. L. (2018) · Nano LIFE · doi:10.1142/s1793984418500046 · Cited by 2

From Identification to Function: Current Strategies to Prioritise and Follow-Up GWAS Results

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Deconvoluting essential gene signatures for cancer growth from genomic expression in compound-treated cells

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Mapping regulators of cell fate determination: Approaches and challenges

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Towards an Integrated Map of Genetic Interactions in Cancer CellsPreprint

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Programmed genome editing of the omega-1 ribonuclease 1 of the blood fluke, Schistosoma mansoniPreprint

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