High-throughput functional genomics using CRISPR-Cas9

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Genome-Wide CRISPR/Cas9 Screening Unveils a Novel Target ATF7IP–SETDB1 Complex for Enhancing Difficult-to-Express Protein Production

Kim, S. H., Park, J.-H., Shin, S., Shin, S., Chun, D., Kim, Y., Yoo, J., You, W., Lee, J. S., & Lee, G. M. (2024) · ACS Synthetic Biology · doi:10.1021/acssynbio.3c00646 · Cited by 14

GLiDe: a web-based genome-scale CRISPRi sgRNA design tool for prokaryotes

Xiang, T., Feng, H., Xing, X., & Zhang, C. (2025) · BMC Bioinformatics · doi:10.1186/s12859-024-06012-0 · Cited by 13

Volatile Organic Compound–Drug Receptor Interactions: A Potential Tool for Drug Design in the Search for Remedies for Increasing Toxic Occupational Exposure

Ogbodo, J. O., Egba, S. I., Ikechukwu, G. C., Paul, P. C., Mba, J. O., Ugwu, O. P.-C., & Ezike, T. C. (2025) · Processes · doi:10.3390/pr13010154 · Cited by 13

PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation

Hu, S. W., Jeong, S., Jiang, L., Koo, H., Wang, Z., Choi, W. H., Zhu, B., Seok, H., Zhou, Y., Kim, M. G., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-62562-8 · Cited by 13

CRISPR Libraries and Screening

Poirier, J. T. (2017) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2017.10.002 · Cited by 14

The CRISPR/Cas9 System as a Tool to Engineer Chromosomal Translocation In Vivo

Cheong, T.-C., Blasco, R. B., & Chiarle, R. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-0593-1_4 · Cited by 13

Pathway sensor-based functional genomics screening identifies modulators of neuronal activity

Herholt, A., Brankatschk, B., Kannaiyan, N. R., Papiol, S., Wichert, S. P., Wehr, M. C., & Rossner, M. J. (2018) · Scientific Reports · doi:10.1038/s41598-018-36008-9 · Cited by 13

Integrate CRISPR/Cas9 for protein expression of HLA-B*38:68Q via precise gene editing

Yin, Y., Reed, E. F., & Zhang, Q. (2019) · Scientific Reports · doi:10.1038/s41598-019-44336-7 · Cited by 13

Decoding pluripotency: Genetic screens to interrogate the acquisition, maintenance, and exit of pluripotency

Li, Q. V., Rosen, B. P., & Huangfu, D. (2019) · WIREs Systems Biology and Medicine · doi:10.1002/wsbm.1464 · Cited by 13

CRISPR/Cas-Mediated Abiotic Stress Tolerance in Crops

Ahmad, A., Ashraf, S., Munawar, N., Jamil, A., Ghaffar, A., & Shahbaz, M. (2021) · Springer eBooks · doi:10.1007/978-981-15-7142-8_6 · Cited by 13

Genome-scale CRISPR-Cas9 knockout screening in nasopharyngeal carcinoma for radiosensitive and radioresistant genes

Zhou, Z., Chen, G., Shen, M., Li, J., Liu, K., Liu, M., Shi, S., Yang, D., Chen, W., Chen, S., et al. (2023) · Translational Oncology · doi:10.1016/j.tranon.2023.101625 · Cited by 13

Circular RNAs: pivotal role in the leukemogenesis and novel indicators for the diagnosis and prognosis of acute myeloid leukemia

Rahmati, A., Mafi, A., Soleymani, F., Aghdam, Z. B., Masihipour, N., Ghezelbash, B., Asemi, R., Aschner, M., Vakili, O., Homayoonfal, M., et al. (2023) · Frontiers in Oncology · doi:10.3389/fonc.2023.1149187 · Cited by 13

Genome-wide CRISPR/Cas9 screen shows that loss of GET4 increases mitochondria-endoplasmic reticulum contact sites and is neuroprotective

Wilson, E. L., Yu, Y., Leal, N. S., Woodward, J. A., Patikas, N., Morris, J. L., Field, S. F., Plumbly, W., Paupe, V., Chowdhury, S. R., et al. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06568-y · Cited by 14

Genetic screens and functional genomics using CRISPR /Cas9 technology

Hartenian, E., & Doench, J. G. (2015) · FEBS Journal · doi:10.1111/febs.13248 · Cited by 100

High‐throughput screens in mammalian cells using the CRISPR‐Cas9 system

Peng, J., Zhou, Y., Zhu, S., & Wei, W. (2015) · FEBS Journal · doi:10.1111/febs.13251 · Cited by 60

Genome-scale CRISPR-Cas9 Knockout and Transcriptional Activation Screening

Joung, J., Konermann, S., Gootenberg, J. S., Abudayyeh, O. O., Platt, R. J., Brigham, M. D., Sanjana, N. E., & Zhang, F. (2017) · Nature Protocols · doi:10.1038/nprot.2017.016 · Cited by 1,243

The Current Situation and Development Prospect of Whole-Genome Screening

Yang, C., Lei, Y., Ren, T., & Yao, M. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25010658 · Cited by 12

Prion Diseases

Pagel, M. D. (1996) · Trends in Neurosciences · doi:10.1016/s0166-2236(96)60033-2