The double life of a B-1 cell: self-reactivity selects for protective effector functions

Predominant Autoantibody Production by Early Human B Cell Precursors

Wardemann, H., Yurasov, S., Schaefer, A., Young, J. W., Meffre, E., & Nussenzweig, M. C. (2003) · Science · doi:10.1126/science.1086907 · Cited by 2,088 · see citing works

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

Moro, K., Yamada, T., Tanabe, M., Takeuchi, T., Ikawa, T., Kawamoto, H., Furusawa, J.-I., Ohtani, M., Fujii, H., & Koyasu, S. (2009) · Nature · doi:10.1038/nature08636 · Cited by 1,994 · see citing works

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

Blair, P. A., Noreña, L. Y., Flores-Borja, F., Rawlings, D. J., Isenberg, D. A., Ehrenstein, M. R., & Mauri, C. (2010) · Immunity · doi:10.1016/j.immuni.2009.11.009 · Cited by 1,574 · see citing works

MACROPHAGE RECEPTORS AND IMMUNE RECOGNITION

Taylor, P. R., Martínez‐Pomares, L., Stacey, M. A., Lin, H.-H., Brown, G. D., & Gordon, S. (2005) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115816 · Cited by 1,325 · see citing works

A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

Yanaba, K., Bouaziz, J., Haas, K. M., Poe, J. C., Fujimoto, M., & Tedder, T. F. (2008) · Immunity · doi:10.1016/j.immuni.2008.03.017 · Cited by 1,239 · see citing works

Marginal Zone and B1 B Cells Unite in the Early Response against T-Independent Blood-Borne Particulate Antigens

Martin, F., Oliver, A. M., & Kearney, J. F. (2001) · Immunity · doi:10.1016/s1074-7613(01)00129-7 · Cited by 987 · see citing works

Chronic Intestinal Inflammatory Condition Generates IL-10-Producing Regulatory B Cell Subset Characterized by CD1d Upregulation

Mizoguchi, A., Mizoguchi, E., Takedatsu, H., Blumberg, R. S., & Bhan, A. K. (2002) · Immunity · doi:10.1016/s1074-7613(02)00274-1 · Cited by 978 · see citing works

Control of Early Viral and Bacterial Distribution and Disease by Natural Antibodies

Ochsenbein, A. F., Fehr, T. H., Lutz, C., Suter, M., Brombacher, F., Hengartner, H., & Zinkernagel, R. M. (1999) · Science · doi:10.1126/science.286.5447.2156 · Cited by 911 · see citing works

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

Moir, S. L., Ho, J., Malaspina, A., Wang, W., DiPoto, A. C., O’Shea, M. A., Roby, G. A., Kottilil, S., Arthos, J. A., Proschan, M. A., et al. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20072683 · Cited by 894 · see citing works

Marginal-zone B cells

Martin, F., & Kearney, J. F. (2002) · Nature reviews. Immunology · doi:10.1038/nri799 · Cited by 867 · see citing works

Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire

Weller, S. (2004) · Blood · doi:10.1182/blood-2004-01-0346 · Cited by 816 · see citing works

The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice.

Hayakawa, K., Hardy, R. R., Parks, D. R., & Herzenberg, L. A. (1983) · The Journal of Experimental Medicine · doi:10.1084/jem.157.1.202 · Cited by 814 · see citing works

Origins and Functions of B-1 Cells with Notes on the Role of CD5

Berland, R., & Wortis, H. H. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.100301.064833 · Cited by 745 · see citing works

Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity

Shaw, P. X., Hörkkö, S., Chang, M.-K., Curtiss, L. K., Palinski, W., Silverman, G. J., & Witztum, J. L. (2000) · Journal of Clinical Investigation · doi:10.1172/jci8472 · Cited by 674 · see citing works

B-1a and B-1b Cells Exhibit Distinct Developmental Requirements and Have Unique Functional Roles in Innate and Adaptive Immunity to S. pneumoniae

Haas, K. M., Poe, J. C., Steeber, D. A., & Tedder, T. F. (2005) · Immunity · doi:10.1016/j.immuni.2005.04.011 · Cited by 628 · see citing works

Progenitors for Ly-1 B cells are distinct from progenitors for other B cells.

Hayakawa, K., Hardy, R. R., Herzenberg, L. A., & Herzenberg, L. A. (1985) · The Journal of Experimental Medicine · doi:10.1084/jem.161.6.1554 · Cited by 614 · see citing works

B-1 and B-2 Cell–Derived Immunoglobulin M Antibodies Are Nonredundant Components of the Protective Response to Influenza Virus Infection

Baumgarth, N., Herman, O. C., Jager, G. C., Brown, L. E., Herzenberg, L. A., & Chen, J. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.2.271 · Cited by 583 · see citing works

Origin of Murine B Cell Lineages

Kantor, A. B., & Herzenberg, L. A. (1993) · Annual Review of Immunology · doi:10.1146/annurev.iy.11.040193.002441 · Cited by 578 · see citing works

Positive Selection of Natural Autoreactive B Cells

Hayakawa, K., Asano, M., Shinton, S. A., Gui, M., Allman, D., Stewart, C. L., Silver, J. E., & Hardy, R. R. (1999) · Science · doi:10.1126/science.285.5424.113 · Cited by 577 · see citing works

B cell receptor signal strength determines B cell fate

Casola, S. S., Otipoby, K. L., Alimzhanov, M. B., Humme, S., Uyttersprot, N., Kutok, J. L., Carroll, M. C., & Rajewsky, K. (2004) · Nature Immunology · doi:10.1038/ni1036 · Cited by 561 · see citing works

A Critical Role of Natural Immunoglobulin M in Immediate Defense Against Systemic Bacterial Infection

Boes, M. L., Продеус, А. П., Schmidt, T., Carroll, M. C., & Chen, J. (1998) · The Journal of Experimental Medicine · doi:10.1084/jem.188.12.2381 · Cited by 553 · see citing works

Inherent specificities in natural antibodies: a key to immune defense against pathogen invasion

Baumgarth, N., Tung, J. W., & Herzenberg, L. A. (2005) · Springer Seminars in Immunopathology · doi:10.1007/s00281-004-0182-2 · Cited by 545 · see citing works

CXCL13 Is Required for B1 Cell Homing, Natural Antibody Production, and Body Cavity Immunity

Ansel, K. M., Harris, R. B. S., & Cyster, J. G. (2002) · Immunity · doi:10.1016/s1074-7613(01)00257-6 · Cited by 543 · see citing works

Ly‐1 B (B‐1) cells are the main source of B cell‐derived interleukin 10

O’Garra, A., Chang, R., Go, N. F., Hastings, R., Haughton, G., & Howard, M. (1992) · European Journal of Immunology · doi:10.1002/eji.1830220314 · Cited by 525 · see citing works

The Development and Function of Regulatory B Cells Expressing IL-10 (B10 Cells) Requires Antigen Receptor Diversity and TLR Signals

Yanaba, K., Bouaziz, J.-D., Matsushita, T., Tsubata, T., & Tedder, T. F. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900270 · Cited by 503 · see citing works

Human Lymphocytes Making Rheumatoid Factor and Antibody to ssDNA Belong to Leu-1 + B-Cell Subset

Casali, P., Burastero, S. E., Nakamura, M., Inghirami, G., & Notkins, A. L. (1987) · Science · doi:10.1126/science.3105056 · Cited by 486 · see citing works

Peripheral development of B cells in mouse and man

Carsetti, R., Rosado, M. M., & Wardmann, H. (2004) · Immunological Reviews · doi:10.1111/j.0105-2896.2004.0109.x · Cited by 479 · see citing works

MARGINAL ZONE B CELLS

Pillai, S. S., Cariappa, A., & Moran, S. T. (2004) · Annual Review of Immunology · doi:10.1146/annurev.immunol.23.021704.115728 · Cited by 473 · see citing works

Oxidation-specific epitopes are dominant targets of innate natural antibodies in mice and humans

Chou, M.-Y., Fogelstrand, L., Hartvigsen, K., Hansen, L. F., Woelkers, D., Shaw, P. X., Choi, J., Perkmann, T., Bäckhed, F., Miller, Y. I., et al. (2009) · Journal of Clinical Investigation · doi:10.1172/jci36800 · Cited by 468 · see citing works

A practical approach to multicolor flow cytometry for immunophenotyping

Baumgarth, N., & Roederer, M. (2000) · Journal of Immunological Methods · doi:10.1016/s0022-1759(00)00229-5 · Cited by 451 · see citing works

Rheumatoid Factor Secretion from Human Leu-1 + B Cells

Hardy, R. R., Hayakawa, K., Shimizu, M., Yamasaki, K., & Kishimoto, T. (1987) · Science · doi:10.1126/science.3105057 · Cited by 440 · see citing works

Induction of immunoglobulin and antibody synthesis in vitro by lipopolysaccharides

Anderson, J., Sjöberg, O., & Möller, G. (1972) · European Journal of Immunology · doi:10.1002/eji.1830020410 · Cited by 427 · see citing works

Identification of a B-1 B cell–specified progenitor

Montecino‐Rodriguez, E., Leathers, H., & Dorshkind, K. A. (2006) · Nature Immunology · doi:10.1038/ni1301 · Cited by 426 · see citing works

Regulatory B cells as inhibitors of immune responses and inflammation

Bouaziz, J., Yanaba, K., & Tedder, T. F. (2008) · Immunological Reviews · doi:10.1111/j.1600-065x.2008.00661.x · Cited by 423 · see citing works

B1b Lymphocytes Confer T Cell-Independent Long-Lasting Immunity

Alugupalli, K. R., Leong, J. M., Woodland, R. T., Muramatsu, M., Honjo, T., & Gerstein, R. M. (2004) · Immunity · doi:10.1016/j.immuni.2004.06.019 · Cited by 411 · see citing works

Sequence homologies, N sequence insertion and JH gene utilization in VHDJH joining: implications for the joining mechanism and the ontogenetic timing of Ly1 B cell and B‐CLL progenitor generation.

Gu, H., Förster, I., & Rajewsky, K. (1990) · The EMBO Journal · doi:10.1002/j.1460-2075.1990.tb07382.x · Cited by 392 · see citing works

Para-aortic splanchnopleura from early mouse embryos contains B1a cell progenitors

Godin, I., García‐Porrero, J. A., Coutinho, A., Dieterlen‐Lièvre, F., & Marcos, M. A. R. (1993) · Nature · doi:10.1038/364067a0 · Cited by 387 · see citing works

B‐cell subsets and the mature preimmune repertoire. Marginal zone and B1 B cells as part of a “natural immune memory”

Martin, F., & Kearney, J. F. (2000) · Immunological Reviews · doi:10.1111/j.1600-065x.2000.imr017515.x · Cited by 378 · see citing works

Accelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM

Boes, M. L., Schmidt, T., Linkemann, K., Beaudette-Zlatanova, B. C., Marshak‐Rothstein, A., & Chen, J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.3.1184 · Cited by 370 · see citing works

Expression of the immunoregulatory molecule FcRH4 defines a distinctive tissue-based population of memory B cells

Ehrhardt, G. R. A., Hsu, J. T., Gartland, L., Leu, C.-M., Zhang, S., Davis, R. S., & Cooper, M. D. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20050879 · Cited by 345 · see citing works

Many of the IgA producing plasma cells in murine gut are derived from self-replenishing precursors in the peritoneal cavity

Kroese, F. G. M., Butcher, E. C., Stall, A. M., Lalor, P. A., Adams, S. D., & Herzenberg, L. A. (1989) · International Immunology · doi:10.1093/intimm/1.1.75 · Cited by 344 · see citing works

Circulating CD21 low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells

Rakhmanov, M., Keller, B., Gutenberger, S., Foerster, C., Hoenig, M., Driessen, G. J. A., van der Burg, M., van Dongen, J. J. M., Wiech, E., Visentini, M., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901984106 · Cited by 334 · see citing works

Homeostasis of Peripheral B Cells in the Absence of B Cell Influx from the Bone Marrow

Hao, Z., & Rajewsky, K. (2001) · The Journal of Experimental Medicine · doi:10.1084/jem.194.8.1151 · Cited by 330 · see citing works

Enhanced B-1 Cell Development, But Impaired IgG Antibody Responses in Mice Deficient in Secreted IgM

Boes, M. L., Esau, C., Fischer, M. B., Schmidt, T., Carroll, M. C., & Chen, J. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.160.10.4776 · Cited by 323 · see citing works

Innate and acquired humoral immunities to influenza virus are mediated by distinct arms of the immune system

Baumgarth, N., Herman, O. C., Jager, G. C., Brown, L. E., Herzenberg, L. A., & Herzenberg, L. A. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.5.2250 · Cited by 320 · see citing works

TLR Agonists Selectively Promote Terminal Plasma Cell Differentiation of B Cell Subsets Specialized in Thymus-Independent Responses

Genestier, L., Taillardet, M., Mondière, P., Gheit, H., Bella, C., & Defrance, T. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.12.7779 · Cited by 316 · see citing works

Differential development of progenitor activity for three B-cell lineages.

Kantor, A. B., Stall, A. M., Adams, S. D., Herzenberg, L. A., & Herzenberg, L. A. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.8.3320 · Cited by 314 · see citing works

CD5-Mediated Negative Regulation of Antigen Receptor-Induced Growth Signals in B-1 B Cells

Bikah, G., Carey, J., Ciallella, J. R., Tarakhovsky, A., & Bondada, S. (1996) · Science · doi:10.1126/science.274.5294.1906 · Cited by 306 · see citing works

Regulation of B1 cell migration by signals through Toll-like receptors

Ha, S.-A., Tsuji, M., Suzuki, K., Meek, B., YASUDA, N., Kaisho, T., & Fagarasan, S. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20061041 · Cited by 290 · see citing works

IgM in microbial infections: Taken for granted?

Racine, R., & Winslow, G. M. (2009) · Immunology Letters · doi:10.1016/j.imlet.2009.06.003 · Cited by 269 · see citing works

Natural Antibody and Complement Mediate Neutralization of Influenza Virus in the Absence of Prior Immunity

Jayasekera, J. P., Moseman, E. A., & Carroll, M. C. (2007) · Journal of Virology · doi:10.1128/jvi.02128-06 · Cited by 268 · see citing works

Reduced life span of anergic self-reactive B cells in a double-transgenic model.

Fulcher, D. A., & Basten, A. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.179.1.125 · Cited by 257 · see citing works

Role of B-1a cells in autoimmunity

Duan, B., & Morel, L. (2006) · Autoimmunity Reviews · doi:10.1016/j.autrev.2005.10.007 · Cited by 256 · see citing works

B-1a B Cells that Link the Innate and Adaptive Immune Responses Are Lacking in the Absence of the Spleen

Wardemann, H., Boehm, T. L. J., Dear, N. T., & Carsetti, R. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20011140 · Cited by 254 · see citing works

Toll‐like receptors – sentries in the B‐cell response

Bekeredjian-Ding, I., & Jego, G. (2009) · Immunology · doi:10.1111/j.1365-2567.2009.03173.x · Cited by 249 · see citing works

Cutting Edge: Novel Function of B Cell-Activating Factor in the Induction of IL-10–Producing Regulatory B Cells

Yang, M., Sun, L., Wang, S., Ko, K., Xu, H., Zheng, B., Cao, X., & Lu, L. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.0902551 · Cited by 243 · see citing works

Dual role for B-1a cells in immunity to influenza virus infection

Choi, Y. S., & Baumgarth, N. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20080979 · Cited by 243 · see citing works

B‐1 cells: the lineage question revisited

Herzenberg, L. A. (2000) · Immunological Reviews · doi:10.1111/j.1600-065x.2000.imr017520.x · Cited by 240 · see citing works

The Broad Antibacterial Activity of the Natural Antibody Repertoire Is Due to Polyreactive Antibodies

Zhou, Z., Zhang, Y., Hu, Y., Wahl, L. M., Cisar, J. O., & Notkins, A. L. (2007) · Cell Host & Microbe · doi:10.1016/j.chom.2007.01.002 · Cited by 227 · see citing works

B Cell Antigen Receptor Specificity and Surface Density Together Determine B-1 versus B-2 Cell Development

Lam, K., & Rajewsky, K. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.190.4.471 · Cited by 223 · see citing works

IgM Antibodies to Apoptosis-Associated Determinants Recruit C1q and Enhance Dendritic Cell Phagocytosis of Apoptotic Cells

Chen, Y., Park, Y., Patel, E. S., & Silverman, G. J. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0804191 · Cited by 221 · see citing works

Treatment of murine CD5− B cells with anti-lg, but not LPS, induces surface CD5: two B-cell activation pathways

Ying-zl, C., Rabin, E. M., & Wortis, H. H. (1991) · International Immunology · doi:10.1093/intimm/3.5.467 · Cited by 221 · see citing works

Identification of the target self-antigens in reperfusion injury

Zhang, M., Alicot, E. M., Chiu, I. M., Li, J., Verna, N., Vorup‐Jensen, T., Kessler, B. M., Shimaoka, M., Chan, R. K., Friend, D. S., et al. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20050390 · Cited by 221 · see citing works

Cd5 Maintains Tolerance in Anergic B Cells

Hippen, K. L., Tze, L. E., & Behrens, T. W. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.191.5.883 · Cited by 214 · see citing works

An unbiased analysis of V(H)-D-J(H) sequences from B-1a, B-1b, and conventional B cells

Kantor, A. B., Merrill, C., Herzenberg, L. A., & Hillson, J. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.158.3.1175 · Cited by 209 · see citing works

A checkpoint for autoreactivity in human IgM+ memory B cell development

Tsuiji, M., Yurasov, S., Velinzon, K., Thomas, S., Nussenzweig, M. C., & Wardemann, H. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20052033 · Cited by 209 · see citing works

The repertoire of serum IgM in normal mice is largely independent of external antigenic contact

Haury, M., Sundblad, A., Grandien, A., Barreau, C., Coutinho, A., & Nóbrega, A. (1997) · European Journal of Immunology · doi:10.1002/eji.1830270635 · Cited by 207 · see citing works

Upon TLR9 Signaling, CD5+ B Cells Control the IL-12-Dependent Th1-Priming Capacity of Neonatal DCs

Sun, C., Dériaud, E., Leclerc, C., & Lo‐Man, R. (2005) · Immunity · doi:10.1016/j.immuni.2005.02.008 · Cited by 205 · see citing works

Isotypes and specificities of immunoglobulins produced by germ‐free mice fed chemically defined ultrafiltered “antigen‐free” diet

Hooijkaas, H., Benner, R., Pleasants, J. R., & Wostmann, B. S. (1984) · European Journal of Immunology · doi:10.1002/eji.1830141212 · Cited by 198 · see citing works

Siglec-G is a B1 cell–inhibitory receptor that controls expansion and calcium signaling of the B1 cell population

Hoffmann, A., Kerr, S. C., Jellusova, J., Zhang, J., Weisel, F. J., Wellmann, U., Winkler, T., Kneitz, B., Crocker, P. R., & Nitschke, L. (2007) · Nature Immunology · doi:10.1038/ni1480 · Cited by 193 · see citing works

The development and repertoire of B-1 cells (CD5 B cells)

Kantor, A. B. (1991) · Immunology Today · doi:10.1016/0167-5699(91)90136-h · Cited by 193 · see citing works

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice

Rodriguez‐Manzanet, R., Sanjuán, M. A. F., Wu, H. Y., Quintana, F. J., Xiao, S., Anderson, A. C., Weiner, H. L., Green, D. R., & Kuchroo, V. K. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910359107 · Cited by 182 · see citing works

Division and differentiation of natural antibody-producing cells in mouse spleen

Yang, Y., Tung, J. W., Ghosn, E., Herzenberg, L. A., & Herzenberg, L. A. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0700001104 · Cited by 181 · see citing works

The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response

Gil‐Cruz, C., Bobat, S., Marshall, J. L., Kingsley, R. A., Ross, E. A., Henderson, I. R., Leyton, D. L., Coughlan, R. E., Khan, M., Jensen, K. T., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0812431106 · Cited by 172 · see citing works

Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse.

Murakami, M., Tsubata, T., Shinkura, R., Nisitani, S., Okamoto, M., Yoshioka, H., Usui, T., Miyawaki, S., & Honjo, T. (1994) · The Journal of Experimental Medicine · doi:10.1084/jem.180.1.111 · Cited by 169 · see citing works

Feedback regulation of murine Ly‐1 B cell development

Lalor, P. A., Herzenberg, L. A., Adams, S. D., & Stall, A. M. (1989) · European Journal of Immunology · doi:10.1002/eji.1830190315 · Cited by 165 · see citing works

Somatic diversification in the absence of antigen-driven responses is the hallmark of the IgM+IgD+CD27+ B cell repertoire in infants

Weller, S., Mamani‐Matsuda, M., Pïcard, C., Cordier, C., Lecoeuche, D., Gauthier, F., Weill, J., & Reynaud, C. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20071555 · Cited by 161 · see citing works

CD9 Is a Unique Marker for Marginal Zone B Cells, B1 Cells, and Plasma Cells in Mice

Won, W.-J., & Kearney, J. F. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.11.5605 · Cited by 160 · see citing works

Fetal B-cell lymphopoiesis and the emergence of B-1-cell potential

Dorshkind, K. A., & Montecino‐Rodriguez, E. (2007) · Nature reviews. Immunology · doi:10.1038/nri2019 · Cited by 159 · see citing works

The functional interactions of commensal bacteria with intestinal secretory IgA

Macpherson, A. J., & Slack, E. M. C. (2007) · Current Opinion in Gastroenterology · doi:10.1097/mog.0b013e3282f0d012 · Cited by 158 · see citing works

Peritoneal Cavity B Cells Are Precursors of Splenic IgM Natural Antibody-Producing Cells

Kawahara, T., Ohdan, H., Zhao, G., Yang, Y., & Sykes, M. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.10.5406 · Cited by 157 · see citing works

Identification and Characterization of a Human CD5+ Pre-Naive B Cell Population

Lee, J., Kuchen, S., Fischer, R. T., Chang, S., & Lipsky, P. E. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803391 · Cited by 150 · see citing works

CD43 (S7) expression identifies peripheral B cell subsets.

Wells, S. M., Kantor, A. B., & Stall, A. M. (1994) · The Journal of Immunology · doi:10.4049/jimmunol.153.12.5503 · Cited by 149 · see citing works

The Role of IL-5 for Mature B-1 Cells in Homeostatic Proliferation, Cell Survival, and Ig Production

Moon, B.-G., Τακακι, S., Miyake, K., & Takatsu, K. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.10.6020 · Cited by 148 · see citing works

Serum immunoglobulin levels and naturally occurring antibodies against carbohydrate antigens in germ‐free BALB/c mice fed chemically defined ultrafiltered diet

Bos, N. A., Kimura, H., Meeuwsen, C. G., Visser, H. D., Hazenberg, M. P., Wostmann, B. S., Pleasants, J. R., Benner, R., & Marcus, D. M. (1989) · European Journal of Immunology · doi:10.1002/eji.1830191223 · Cited by 137 · see citing works

Natural antibodies and the autoimmunity of atherosclerosis

Binder, C. J., & Silverman, G. J. (2004) · Springer Seminars in Immunopathology · doi:10.1007/s00281-004-0185-z · Cited by 136 · see citing works

A two‐phase model of B‐cell activation

Baumgarth, N. (2000) · Immunological Reviews · doi:10.1034/j.1600-065x.2000.00606.x · Cited by 135 · see citing works

Cyclin D2 is essential for BCR-mediated proliferation and CD5 B cell development

Solvason, N. W., Wu, W. W., Parry, D., Mahony, D., Lam, E. W. ‐., Glassford, J., Klaus, G. G. B., Siciński, P., Weinberg, R. A., Liu, Y.-J., et al. (2000) · International Immunology · doi:10.1093/intimm/12.5.631 · Cited by 135 · see citing works

Ontogeny of terminal deoxynucleotidyl transferase-positive cells in lymphohemopoietic tissues of rat and mouse.

Gregoire, K. E., Goldschneider, I., Barton, R. W., & Bollum, F. J. (1979) · PubMed · Cited by 134 · see citing works

Suppressive functions of activated B cells in autoimmune diseases reveal the dual roles of Toll‐like receptors in immunity

Lampropoulou, V., Calderon‐Gomez, E., Roch, T., Neves, P., Shen, P., Stervbo, U., Boudinot, P., Anderton, S. M., & Fillatreau, S. (2010) · Immunological Reviews · doi:10.1111/j.0105-2896.2009.00855.x · Cited by 130 · see citing works

Interleukin 9–induced In Vivo Expansion of the B-1 Lymphocyte Population

Vink, A., Warnier, G., Brombacher, F., & Renauld, J. (1999) · The Journal of Experimental Medicine · doi:10.1084/jem.189.9.1413 · Cited by 129 · see citing works

B-1 B cells: development, selection, natural autoantibody and leukemia

Hardy, R. R. (2006) · Current Opinion in Immunology · doi:10.1016/j.coi.2006.07.010 · Cited by 127 · see citing works

Mac-1-Negative B-1b Phenotype of Natural Antibody-Producing Cells, Including Those Responding to Galα1,3Gal Epitopes in α1,3-Galactosyltransferase-Deficient Mice

Ohdan, H., Swenson, K. G., Gray, H. S. K., Yang, Y., Xu, Y., Thall, A. D., & Sykes, M. (2000) · The Journal of Immunology · doi:10.4049/jimmunol.165.10.5518 · Cited by 126 · see citing works

Phosphoinositide 3-Kinase p110δ Regulates Natural Antibody Production, Marginal Zone and B-1 B Cell Function, and Autoantibody Responses

Durand, C., Hartvigsen, K., Fogelstrand, L., Kim, S., Iritani, S., Vanhaesebroeck, B., Witztum, J. L., Puri, K. D., & Gold, M. R. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900432 · Cited by 123 · see citing works

Pathogenic Natural Antibodies Recognizing Annexin IV Are Required to Develop Intestinal Ischemia-Reperfusion Injury

Kulik, L. N., Fleming, S. D., Moratz, C. M., Reuter, J. W., Novikov, A., Chen, K., Andrews, K. A., Markaryan, A., Quigg, R. J., Silverman, G. J., et al. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803980 · Cited by 121 · see citing works

Identification and analysis of a novel human surface CD5- B lymphocyte subset producing natural antibodies

Kasaian, M. T., Ikematsu, H., & Casali, P. (1992) · The Journal of Immunology · doi:10.4049/jimmunol.148.9.2690 · Cited by 119 · see citing works

B1 Cells Contribute to Serum IgM, But Not to Intestinal IgA, Production in Gnotobiotic Ig Allotype Chimeric Mice

Thurnheer, M. C., Zuercher, A. W., Cebra, J. J., & Bos, N. A. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.9.4564 · Cited by 117 · see citing works

Abnormal transcription factor induction through the surface immunoglobulin M receptor of B-1 lymphocytes.

Morris, D. L., & Rothstein, T. L. (1993) · The Journal of Experimental Medicine · doi:10.1084/jem.177.3.857 · Cited by 111 · see citing works

Antigen-specific B-1a antibodies induced by Francisella tularensis LPS provide long-term protection against F. tularensis LVS challenge

Cole, L. E., Yang, Y., Elkins, K. L., Fernandez, E. T., Qureshi, N., Shlomchik, M. J., Herzenberg, L. A., Herzenberg, L. A., & Vogel, S. N. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813411106 · Cited by 111 · see citing works

B-1 cells and their reactivity with the murine intestinal microflora

Kroese, F. G. M., de Waard, R., & Bos, N. A. (1996) · Seminars in Immunology · doi:10.1006/smim.1996.0003 · Cited by 109 · see citing works

Cutting Edge: Spontaneously Ig-Secreting B-1 Cells Violate the Accepted Paradigm for Expression of Differentiation-Associated Transcription Factors

Tumang, J. R., Francés, R., Yeo, S. G., & Rothstein, T. L. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.174.6.3173 · Cited by 108 · see citing works

A differentiation pathway for B1 cells in adult bone marrow

Esplin, B. L., Welner, R. S., Zhang, Q., Borghesi, L., & Kincade, P. W. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0811632106 · Cited by 105 · see citing works

Induction of B-cell development in adult mice reveals the ability of bone marrow to produce B-1a cells

Düber, S., Hafner, M., Krey, M., Lienenklaus, S., Roy, B., Hobeika, E., Reth, M. G., Buch, T., Waisman, A., Kretschmer, K., et al. (2009) · Blood · doi:10.1182/blood-2009-04-218156 · Cited by 105 · see citing works

CD11b expression distinguishes sequential stages of peritoneal B-1 development

Ghosn, E., Yang, Y., Tung, J. W., Herzenberg, L. A., & Herzenberg, L. A. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0712350105 · Cited by 105 · see citing works

Different Kinetics of Blimp-1 Induction in B Cell Subsets Revealed by Reporter Gene

Fairfax, K. A., Corcoran, L. M., Pridans, C., Huntington, N. D., Kallies, A., Nutt, S. L., & Tarlinton, D. M. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.7.4104 · Cited by 100 · see citing works

Ontogeny of Terminal Deoxynucleotidyl Transferase-Positive Cells in Lymphohemopoletic Tissues of Rat and Mouse

Gregoire, K. E., Goldschneider, I., Barton, R. W., & Bollum, F. J. (1979) · The Journal of Immunology · doi:10.4049/jimmunol.123.3.1347 · Cited by 99 · see citing works

B‐1a, B‐1b and B‐2 B cells display unique VHDJH repertoires formed at different stages of ontogeny and under different selection pressures.

Tornberg, U., & Holmberg, D. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07157.x · Cited by 95 · see citing works

Enhanced IgA Class Switching in Marginal Zone and B1 B Cells Relative to Follicular/B2 B Cells

Kaminski, D. A., & Stavnezer, J. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.177.9.6025 · Cited by 90 · see citing works

Peritoneal CD5+ B-1 Cells Have Signaling Properties Similar to Tolerant B Cells

Wong, S. C., Chew, W.-K., Tan, J. E.-L., Melendez, A. J., Francis, F., & Lam, K. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m202460200 · Cited by 90 · see citing works

B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion

Savitsky, D. A., & Calame, K. L. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20060411 · Cited by 89 · see citing works

From Natural Polyreactive Autoantibodies to A La Carte Monoreactive Antibodies to Infectious Agents: Is It a Small World after All?

Bouvet, J., & Dighiero, G. (1998) · Infection and Immunity · doi:10.1128/iai.66.1.1-4.1998 · Cited by 87 · see citing works

Extravascular T-cell recruitment requires initiation begun by Vα14+ NKT cells and B-1 B cells

Askenase, P. W., Szczepanik, M., Itakura, A., Kiener, C., & Campos, R. A. (2004) · Trends in Immunology · doi:10.1016/j.it.2004.06.003 · Cited by 83 · see citing works

Administration of interleukin ‐5 or ‐10 activates peritoneal B‐1 cells and induces autoimmune hemolytic anemia in anti‐erythrocyte autoantibody‐transgenic mice

Nisitani, S., Tsubata, T., Murakami, M., & Honjo, T. (1995) · European Journal of Immunology · doi:10.1002/eji.1830251110 · Cited by 81 · see citing works

Adult BM generates CD5+ B1 cells containing abundant N‐region additions

Holodick, N. E., Repetny, K., Zhong, X., & Rothstein, T. L. (2009) · European Journal of Immunology · doi:10.1002/eji.200838920 · Cited by 79 · see citing works

Oct2 enhances antibody-secreting cell differentiation through regulation of IL-5 receptor α chain expression on activated B cells

Emslie, D., D’Costa, K., Hasbold, J., Metcalf, D., Takatsu, K., Hodgkin, P. D., & Corcoran, L. M. (2008) · The Journal of Experimental Medicine · doi:10.1084/jem.20072049 · Cited by 79 · see citing works

Autoimmunity-Prone B-L (Cd5 B) Cells, Natural Antibodies and Self Recognition

Kasaian, M. T., & Casali, P. (1993) · Autoimmunity · doi:10.3109/08916939309115755 · Cited by 78 · see citing works

B cell autonomous TLR signaling and autoimmunity

Meyer‐Bahlburg, A., & Rawlings, D. J. (2008) · Autoimmunity Reviews · doi:10.1016/j.autrev.2007.11.027 · Cited by 78 · see citing works

Roles of B‐1 and B‐2 cells in innate and acquired IgA‐mediated immunity

Suzuki, K., Maruya, M., Kawamoto, S., & Fagarasan, S. (2010) · Immunological Reviews · doi:10.1111/j.1600-065x.2010.00941.x · Cited by 76 · see citing works

Immunoglobulins did not arise in evolution to fight infection

Stewart, J. R. (1992) · Immunology Today · doi:10.1016/0167-5699(92)90088-o · Cited by 74 · see citing works

Innate Pathways to B cell Activation and Tolerance

Crampton, S., Voynova, E., & Bolland, S. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2009.05123.x · Cited by 73 · see citing works

A selective defect in IgM antigen receptor synthesis and transport causes loss of cell surface IgM expression on tolerant B lymphocytes.

Bell, S. E., & Goodnow, C. C. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06324.x · Cited by 72 · see citing works

The Unique Antigen Receptor Signaling Phenotype of B-1 Cells Is Influenced by Locale but Induced by Antigen

Chumley, M. J., Porto, J. M. D., & Cambier, J. C. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.4.1735 · Cited by 62 · see citing works

Evaluation of intranuclear BrdU detection procedures for use in multicolor flow cytometry

Rothaeusler, K., & Baumgarth, N. (2006) · Cytometry Part A · doi:10.1002/cyto.a.20252 · Cited by 58 · see citing works

Essential role of membrane cholesterol in accelerated BCR internalization and uncoupling from NF-κB in B cell clonal anergy

Bléry, M., Tze, L. E., Miosge, L. A., Jun, J. E., & Goodnow, C. C. (2006) · The Journal of Experimental Medicine · doi:10.1084/jem.20060552 · Cited by 58 · see citing works

From the fetal liver to spleen and gut: the highway to natural antibody

Rosado, M. M., Aranburu, A., Capolunghi, F., Giorda, E., Cascioli, S., Cenci, F., Petrini, S., Miller, E., Leanderson, T., Bottazzo, G. F., et al. (2009) · Mucosal Immunology · doi:10.1038/mi.2009.15 · Cited by 57 · see citing works

Natural killer T cells and innate immune B cells from lupus‐prone NZB/W mice interact to generate IgM and IgG autoantibodies

Takahashi, T., & Strober, S. (2007) · European Journal of Immunology · doi:10.1002/eji.200737656 · Cited by 56 · see citing works

Regulation of BCR Signal Transduction in B-1 Cells Requires the Expression of the Src Family Kinase Lck

Porto, J. M. D., Burke, K. M., & Cambier, J. C. (2004) · Immunity · doi:10.1016/j.immuni.2004.07.018 · Cited by 56 · see citing works

Migration and Differentiation of Autoreactive B-1 Cells Induced by Activated γ/δ T Cells in Antierythrocyte Immunoglobulin Transgenic Mice

Watanabe, N., Ikuta, K., Fagarasan, S., Yazumi, S., Chiba, T., & Honjo, T. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.11.1577 · Cited by 54 · see citing works

Unique properties of memory B cells of different isotypes

Kurosaki, T., Aiba, Y., Kometani, K., Moriyama, S., & Takahashi, Y. (2010) · Immunological Reviews · doi:10.1111/j.1600-065x.2010.00939.x · Cited by 53 · see citing works

B1 and B2 cells differ in their potential to switch immunoglobulin isotype

Tarlinton, D. M., McLean, M., & Nossal, G. J. V. (1995) · European Journal of Immunology · doi:10.1002/eji.1830251228 · Cited by 51 · see citing works

CD19+CD5+ B Cells in Primary IgA Nephropathy

He, Y., Ruijing, X., Xiang, J., Yanping, J., Chen, L., Li, L., Dingping, Y., Xinti, T., Jingyi, L., Zhiqing, T., et al. (2008) · Journal of the American Society of Nephrology · doi:10.1681/asn.2007121303 · Cited by 43 · see citing works

Continual Signaling Is Responsible for Constitutive ERK Phosphorylation in B-1a Cells

Holodick, N., Tumang, J. R., & Rothstein, T. (2009) · Molecular Immunology · doi:10.1016/j.molimm.2009.06.011 · Cited by 43 · see citing works

B1 Cells Promote Pancreas Infiltration by Autoreactive T Cells

Ryan, G. A., Wang, C. J., Chamberlain, J. L., Attridge, K., Schmidt, E. M., Kenefeck, R., Clough, L. E., Dunussi‐Joannopoulos, K., Toellner, K., & Walker, L. S. K. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1000856 · Cited by 41 · see citing works

CD5+/Mac-1− peritoneal B cells: A novel B cell subset that exhibits characteristics of B-1 cells

Hastings, W. D., Gurdak, S. M., Tumang, J. R., & Rothstein, T. L. (2006) · Immunology Letters · doi:10.1016/j.imlet.2006.01.002 · Cited by 40 · see citing works

Negative regulation of B cell receptor-mediated signaling in B-1 cells through CD5 and Ly49 co-receptors via Lyn kinase activity

Ochi, H., & Watanabe, T. (2000) · International Immunology · doi:10.1093/intimm/12.10.1417 · Cited by 39 · see citing works

Impairment of the Antipolysaccharide Response in Splenectomized Patients Is Due to the Lack of Immunoglobulin M Memory B Cells

Carsetti, R., Pantosti, A., & Quinti, I. (2006) · The Journal of Infectious Diseases · doi:10.1086/501375 · Cited by 32 · see citing works

B-Cell Immunophenotyping

Baumgarth, N. (2004) · Methods in cell biology · doi:10.1016/s0091-679x(04)75027-x · Cited by 31 · see citing works

Defective CD19-dependent signaling in B-1a and B-1b B lymphocyte subpopulations

Sen, G., Wu, H.-J. J., Bikah, G., Venkataraman, C., Robertson, D. A., Snow, E. C., & Bondada, S. (2002) · Molecular Immunology · doi:10.1016/s0161-5890(02)00047-0 · Cited by 31 · see citing works

Identification of Initiator B Cells, a Novel Subset of Activation-Induced Deaminase-Dependent B-1-Like Cells That Mediate Initiation of Contact Sensitivity

Kerfoot, S. M., Szczepanik, M., Tung, J. W., & Askenase, P. W. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.3.1717 · Cited by 30 · see citing works

Antigen Receptor Proximal Signaling in Splenic B-2 Cell Subsets

Li, X., Martin, F., Oliver, A. M., Kearney, J. F., & Carter, R. H. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.5.3122 · Cited by 27 · see citing works

Mechanism of B‐Cell Activation and Paralysis by Thymus‐Independent Antigens

Coutinho, A., Gronowicz, E. S., & Möller, G. (1975) · Scandinavian Journal of Immunology · doi:10.1111/j.1365-3083.1975.tb02603.x · Cited by 25 · see citing works

CD5+ peritoneal B cells express high levels of membrane, but not secretory, C mu mRNA

McIntyre, T. M., Holmes, K. L., Steinberg, A. D., & Kastner, D. L. (1991) · The Journal of Immunology · doi:10.4049/jimmunol.146.10.3639 · Cited by 24 · see citing works

Receptor Sensitivity: When T cells Lose Their Sense of Self

Hogquist, K. A., Starr, T. K., & Jameson, S. C. (2003) · Current Biology · doi:10.1016/s0960-9822(03)00161-1 · Cited by 23 · see citing works

Enhanced trafficking to the pancreatic lymph nodes and auto-antigen presentation capacity distinguishes peritoneal B lymphocytes in non-obese diabetic mice

Alam, C. M., Valkonen, S., Ohls, S., Törnqvist, K., & Hänninen, A. L. M. (2009) · Diabetologia · doi:10.1007/s00125-009-1599-x · Cited by 23 · see citing works

Cutting Edge: B-1 Cells Are Deficient in Lck: Defective B Cell Receptor Signal Transduction in B-1 Cells Occurs in the Absence of Elevated Lck Expression

Francés, R., Tumang, J. R., & Rothstein, T. L. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.1.27 · Cited by 23 · see citing works

Maintenance of Peritoneal B-1a Lymphocytes in the Absence of the Spleen

Kretschmer, K., Stopkowicz, J., Scheffer, S., Greten, T. F., & Weiß, S. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.1.197 · Cited by 21 · see citing works

Normal B‐1 cell development but defective BCR signaling in LCK–/– mice

Ulivieri, C., Valensin, S., Majolini, M. B., Matthews, R. J., & Baldari, C. T. (2003) · European Journal of Immunology · doi:10.1002/immu.200310019 · Cited by 20 · see citing works

Murine Peritoneal Ly‐1 B Cells Do Not Turn Over Rapidly

Deenen, G. J., & Kroese, F. G. M. (1992) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1992.tb24594.x · Cited by 19 · see citing works

B-1 cells modulate oral tolerance in mice.

De-Gennaro, L. A., Popi, A., de Almeida, S. R., Lopes, J. D., & Mariano, M. (2009) · Immunology Letters · doi:10.1016/j.imlet.2009.04.003 · Cited by 16 · see citing works

Characterization of cells of the B lineage in the human adult greater omentum

Boursier, L., Montalto, S. A., Raju, S., Culora, G., & Spencer, J. (2006) · Immunology · doi:10.1111/j.1365-2567.2006.02411.x · Cited by 14 · see citing works

Mls presentation by peritoneal cavity B cells

Riggs, J. E., Howell, K. F., Taylor, J. J., Mahjied, T., Prokopenko, N., Alvarez, J., & Coleman, C. (2004) · Immunobiology · doi:10.1016/j.imbio.2004.03.008 · Cited by 9 · see citing works

Regulation of fucosyltransferase-VII expression in peripheral lymph node high endothelial venules

(1998) · doi:10.1002/(sici)1521-4141(199810)28:10

Structure and function of the immune system in the spleen

Lewis, S. M., Williams, A., & Eisenbarth, S. C. (2019) · Science Immunology · doi:10.1126/sciimmunol.aau6085 · Cited by 1,301 · see citing works

Immune regulatory function of B cells.

Mauri, C., & Bosma, A. (2012) · Annual Review of Immunology · doi:10.1146/annurev-immunol-020711-074934 · Cited by 1,278 · see citing works

Six-of-the-best: unique contributions of γδ T cells to immunology

Vantourout, P., & Hayday, A. (2013) · Nature Reviews Immunology · doi:10.1038/nri3384 · Cited by 1,232 · see citing works

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)

Cossarizza, A., Chang, H., Radbruch, A., Acs, A., Adam, D., Adam‐Klages, S., Agace, W. W., Aghaeepour, N., Akdiş, M., Allez, M., et al. (2019) · European Journal of Immunology · doi:10.1002/eji.201970107 · Cited by 982 · see citing works

Tissue-specific signals control reversible program of localization and functional polarization of macrophages

Okabe, Y., & Medzhitov, R. (2014) · Cell · doi:10.1016/j.cell.2014.04.016 · Cited by 884 · see citing works

Causes, consequences, and reversal of immune system aging

Montecino-Rodriguez, E., Berent-Maoz, B., & Dorshkind, K. (2013) · Journal of Clinical Investigation · doi:10.1172/jci64096 · Cited by 793 · see citing works

Comprehensive Profiling of an Aging Immune System Reveals Clonal GZMK+ CD8+ T Cells as Conserved Hallmark of Inflammaging

Mogilenko, D. A., Shpynov, O., Andhey, P. S., Arthur, L., Swain, A., Esaulova, E., Brioschi, S., Shchukina, I., Kerndl, M., Bambouskova, M., et al. (2021) · Immunity · doi:10.1016/j.immuni.2020.11.005 · Cited by 683 · see citing works

Effects of Omega-3 Fatty Acids on Immune Cells

Gutiérrez, S., Svahn, S. L., & Johansson, M. E. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20205028 · Cited by 588 · see citing works

Immune cell-mediated features of non-alcoholic steatohepatitis

Huby, T., & Gautier, E. L. (2022) · Nature Reviews Immunology · doi:10.1038/s41577-021-00639-3 · Cited by 573 · see citing works

Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies

Chen, B., Cheng, T., & Roffler, S. R. (2021) · ACS Nano · doi:10.1021/acsnano.1c05922 · Cited by 573 · see citing works

Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A

Bunker, J. J., Flynn, T. M., Koval, J., Shaw, D. G., Meisel, M., McDonald, B. D., Ishizuka, I. E., Dent, A. L., Wilson, P. C., Jabrì, B., et al. (2015) · Immunity · doi:10.1016/j.immuni.2015.08.007 · Cited by 557 · see citing works

Guidelines for the use of flow cytometry and cell sorting in immunological studies (third edition)

Cossarizza, A., Chang, H., Radbruch, A., Abrignani, S., Addo, R., Akdis, M., Andrä, I., Andreata, F., Annunziato, F., Arranz, E., et al. (2021) · European Journal of Immunology · doi:10.1002/eji.202170126 · Cited by 531 · see citing works

Redox regulation of immunometabolism

Muri, J., & Köpf, M. (2020) · Nature reviews. Immunology · doi:10.1038/s41577-020-00478-8 · Cited by 501 · see citing works

B Cells, Antibodies, and More

Hoffman, W., Lakkis, F. G., & Chalasani, G. (2015) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.09430915 · Cited by 491 · see citing works

Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes

Diana, J., Simoni, Y., Furio, L., Beaudoin, L., Agerberth, B., Barrat, F. J., & Lehuen, A. (2012) · Nature Medicine · doi:10.1038/nm.3042 · Cited by 428 · see citing works

BAFF and BAFF-Receptor in B Cell Selection and Survival

Smulski, C. R., & Eibel, H. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02285 · Cited by 372 · see citing works

Autophagy in the renewal, differentiation and homeostasis of immune cells

Clarke, A. J., & Simon, A. K. (2019) · Nature Reviews Immunology · doi:10.1038/s41577-018-0095-2 · Cited by 361 · see citing works

Protective Roles of Natural IgM Antibodies

Grönwall, C., Vas, J., & Silverman, G. J. (2012) · Frontiers in Immunology · doi:10.3389/fimmu.2012.00066 · Cited by 358 · see citing works

B-1 B Cell Development in the Fetus and Adult

Montecino‐Rodriguez, E., & Dorshkind, K. A. (2012) · Immunity · doi:10.1016/j.immuni.2011.11.017 · Cited by 353 · see citing works

Adipose tissue-resident immune cells: key players in immunometabolism

Schipper, H. S., Prakken, B., Kalkhoven, E., & Boes, M. (2012) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2012.05.011 · Cited by 342 · see citing works

Rethinking mucosal antibody responses: IgM, IgG and IgD join IgA

Chen, K., Magri, G., Grasset, E. K., & Cerutti, A. (2020) · Nature reviews. Immunology · doi:10.1038/s41577-019-0261-1 · Cited by 339 · see citing works

Mapping the developing human immune system across organs

Suo, C., Dann, E., Goh, I., Jardine, L., Kleshchevnikov, V., Park, J.-E., Botting, R. A., Stephenson, E., Engelbert, J., Tuong, Z. K., et al. (2022) · Science · doi:10.1126/science.abo0510 · Cited by 315 · see citing works

Revisiting Mouse Peritoneal Macrophages: Heterogeneity, Development, and Function

Cassado, A. D. A., D’Império Lima, M. R., & Bortoluci, K. R. (2015) · Frontiers in Immunology · doi:10.3389/fimmu.2015.00225 · Cited by 315 · see citing works

Preterm birth and sustained inflammation: consequences for the neonate

Humberg, A., Fortmann, M. I., Siller, B., Kopp, M., Herting, E., Göpel, W., & Härtel, C. (2020) · Seminars in Immunopathology · doi:10.1007/s00281-020-00803-2 · Cited by 312 · see citing works

Natural IgG autoantibodies are abundant and ubiquitous in human sera, and their number is influenced by age, gender, and disease

Nagele, E. P., Han, M., Acharya, N. K., DeMarshall, C., Kosciuk, M. C., & Nagele, R. G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0060726 · Cited by 309 · see citing works

Integrative Physiology of Pneumonia

Quinton, L. J., Walkey, A. J., & Mizgerd, J. P. (2018) · Physiological Reviews · doi:10.1152/physrev.00032.2017 · Cited by 308 · see citing works

B Cells and Humoral Immunity in Atherosclerosis

Tsiantoulas, D., Diehl, C. J., Witztum, J. L., & Binder, C. J. (2014) · Circulation Research · doi:10.1161/circresaha.113.301145 · Cited by 297 · see citing works

Fishing for mammalian paradigms in the teleost immune system

Sunyer, J. O. (2013) · Nature Immunology · doi:10.1038/ni.2549 · Cited by 297 · see citing works

The molecular pathogenesis of chronic lymphocytic leukaemia

Fabbri, G., & Dalla‐Favera, R. (2016) · Nature reviews. Cancer · doi:10.1038/nrc.2016.8 · Cited by 282 · see citing works

Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells

Magri, G., Miyajima, M., Bascones, S., Mortha, A., Puga, I., Cassis, L., Barra, C., Comerma, L., Chudnovskiy, A., Gentile, M., et al. (2014) · Nature Immunology · doi:10.1038/ni.2830 · Cited by 280 · see citing works

Mitochondria as central hub of the immune system

Breda, C. N. D. S., Davanzo, G. G., Basso, P. J., Câmara, N. O. S., & Moraes‐Vieira, P. M. (2019) · Redox Biology · doi:10.1016/j.redox.2019.101255 · Cited by 280 · see citing works

Chronic Inflammation Links Cardiovascular, Metabolic and Renal Diseases

Manabe, I. (2011) · Circulation Journal · doi:10.1253/circj.cj-11-1184 · Cited by 264 · see citing works

Structure, Function, and Therapeutic Use of IgM Antibodies

Keyt, B. A., Baliga, R., Sinclair, A. M., Carroll, S. F., & Peterson, M. S. (2020) · Antibodies · doi:10.3390/antib9040053 · Cited by 260 · see citing works

Hif1α deletion reveals pro-neoplastic function of B cells in pancreatic neoplasia

Lee, K., Spata, M., Bayne, L., Buza, E., Durham, A., Allman, D., Vonderheide, R., & Simon, M. (2015) · Cancer Discovery · doi:10.1158/2159-8290.cd-15-0822 · Cited by 203 · see citing works

Intestinal Mucosal Mast Cells: Key Modulators of Barrier Function and Homeostasis

Albert-Bayo, M., Paracuellos, I., González-Castro, A. M., Rodríguez‐Urrutia, A., Rodríguez-Lagunas, M. J., Alonso, C., Santos, J., & Vicario, M. (2019) · Cells · doi:10.3390/cells8020135 · Cited by 217 · see citing works

B Cell Development and Maturation

Wang, Y., Liu, J., Burrows, P. D., & Wang, J. O. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-981-15-3532-1_1 · Cited by 217 · see citing works

Defining Natural Antibodies

Holodick, N. E., Rodríguez‐Zhurbenko, N., & Hernández, A. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00872 · Cited by 208 · see citing works

Adaptive (T and B Cells) Immunity and Control by Dendritic Cells in Atherosclerosis

Ait‐Oufella, H., Sage, A. P., Mallat, Z., & Tedgui, A. (2014) · Circulation Research · doi:10.1161/circresaha.114.302761 · Cited by 201 · see citing works

B-1 Cell Heterogeneity and the Regulation of Natural and Antigen-Induced IgM Production

Baumgarth, N. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00324 · Cited by 201 · see citing works

B1 and marginal zone B cells but not follicular B2 cells require Gpx4 to prevent lipid peroxidation and ferroptosis

Muri, J., Thut, H., Bornkamm, G. W., & Kopf, M. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.10.070 · Cited by 198 · see citing works

Vitamin D: Effect on Haematopoiesis and Immune System and Clinical Applications

Medrano, M., Carrillo‐Cruz, E., Montero, I., & Pérez‐Simón, J. A. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19092663 · Cited by 193 · see citing works

B‐1 cells in the bone marrow are a significant source of natural IgM

Choi, Y. S., Dieter, J. A., Rothaeusler, K., Luo, Z. L., & Baumgarth, N. (2011) · European Journal of Immunology · doi:10.1002/eji.201141890 · Cited by 184 · see citing works

Human B‐1 cells take the stage

Rothstein, T. L., Griffin, D. O., Holodick, N. E., Quách, T. D., & Kaku, H. (2013) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12137 · Cited by 183 · see citing works

Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection

Sewald, X., Ladinsky, M. S., Uchil, P. D., Beloor, J., Pi, R., Herrmann, C., Motamedi, N., Murooka, T. T., Brehm, M. A., Greiner, D. L., et al. (2015) · Science · doi:10.1126/science.aab2749 · Cited by 178 · see citing works

Role of the Immune System in the Development of the Central Nervous System

Morimoto, K., & Nakajima, K. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00916 · Cited by 181 · see citing works

The role of B cells and humoral immunity in Mycobacterium tuberculosis infection

Chan, J., Mehta, S., Bharrhan, S., Chen, Y., Achkar, J. M., Casadevall, A., & Flynn, J. L. (2014) · Seminars in Immunology · doi:10.1016/j.smim.2014.10.005 · Cited by 176 · see citing works

Natural IgM: Beneficial Autoantibodies for the Control of Inflammatory and Autoimmune Disease

Grönwall, C., & Silverman, G. J. (2014) · Journal of Clinical Immunology · doi:10.1007/s10875-014-0025-4 · Cited by 175 · see citing works

A small CD11b+ human B1 cell subpopulation stimulates T cells and is expanded in lupus

Griffin, D. O., & Rothstein, T. L. (2011) · The Journal of Experimental Medicine · doi:10.1084/jem.20110978 · Cited by 174 · see citing works

B-lymphocyte lineage cells and the respiratory system

Kato, A., Hulse, K. E., Tan, B. K., & Schleimer, R. P. (2013) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2013.02.023 · Cited by 173 · see citing works

Understanding the Role of the Gut Microbiome in Brain Development and Its Association With Neurodevelopmental Psychiatric Disorders

Dash, S., Syed, Y. A., & Khan, M. R. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.880544 · Cited by 179 · see citing works

The innate immune response to products of phospholipid peroxidation

Weismann, D., & Binder, C. J. (2012) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2012.01.018 · Cited by 172 · see citing works

The enigmatic function of IgD: some answers at last

Gutzeit, C., Chen, K., & Cerutti, A. (2018) · European Journal of Immunology · doi:10.1002/eji.201646547 · Cited by 159 · see citing works

Immune cell interactions in tuberculosis

Flynn, J. L., & Chan, J. (2022) · Cell · doi:10.1016/j.cell.2022.10.025 · Cited by 157 · see citing works

Adipose Tissue Inflammation in the Pathogenesis of Type 2 Diabetes

Kohlgruber, A. C., & Lynch, L. (2015) · Current Diabetes Reports · doi:10.1007/s11892-015-0670-x · Cited by 157 · see citing works

Neonatal T Cells: A Reinterpretation

Rudd, B. D. (2020) · Annual Review of Immunology · doi:10.1146/annurev-immunol-091319-083608 · Cited by 154 · see citing works

Evolution of B Cell Immunity

Parra, D., Takizawa, F., & Sunyer, J. O. (2013) · Annual Review of Animal Biosciences · doi:10.1146/annurev-animal-031412-103651 · Cited by 153 · see citing works

A tolerogenic role for Toll-like receptor 9 is revealed by B-cell interaction with DNA complexes expressed on apoptotic cells

Miles, K., Heaney, J., Sibinska, Z., Salter, D. M., Savill, J., Gray, D., & Gray, M. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1109173109 · Cited by 152 · see citing works

B Cells in Teleost Fish Act as Pivotal Initiating APCs in Priming Adaptive Immunity: An Evolutionary Perspective on the Origin of the B-1 Cell Subset and B7 Molecules

Zhu, L., Lin, A., Shao, T., Nie, L., Dong, W.-R., Xiang, L., & Shao, J.-Z. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1301312 · Cited by 152 · see citing works

Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis

Weber, G. F., Chousterman, B. G., Hilgendorf, I., Robbins, C. S., Theurl, I., Gerhardt, L. M. S., Iwamoto, Y., Quách, T. D., Ali, M., Chen, J. W., et al. (2014) · The Journal of Experimental Medicine · doi:10.1084/jem.20131471 · Cited by 151 · see citing works

Natural IgM in Immune Equilibrium and Harnessing Their Therapeutic Potential

Kaveri, S. V., Silverman, G. J., & Bayry, J. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1102107 · Cited by 150 · see citing works

B1a B cells require autophagy for metabolic homeostasis and self-renewal

Clarke, A. J., Riffelmacher, T., Braas, D., Cornall, R. J., & Simon, A. K. (2018) · The Journal of Experimental Medicine · doi:10.1084/jem.20170771 · Cited by 149 · see citing works

A Hard(y) Look at B-1 Cell Development and Function

Baumgarth, N. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700943 · Cited by 148 · see citing works

Immunosenescence: signaling pathways, diseases and therapeutic targets

Fu, Y., Wang, B., Alu, A., Hong, W., Hong, L., He, X., Shi, H., Cheng, P., & Yang, X. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02371-z · Cited by 157 · see citing works

CD5 Binds to Interleukin-6 and Induces a Feed-Forward Loop with the Transcription Factor STAT3 in B Cells to Promote Cancer

Zhang, C., Xin, H., Zhang, W., Yazaki, P. J., Zhang, Z., Le, K., Li, W., Lee, H., Kwak, L. W., Forman, S. J., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.04.003 · Cited by 145 · see citing works

B-1b Cells Secrete Atheroprotective IgM and Attenuate Atherosclerosis

Rosenfeld, S. M., Perry, H. M., Gonen, A., Prohaska, T. A., Srikakulapu, P., Grewal, S., Das, D., McSkimming, C. C., Taylor, A. M., Tsimikas, S., et al. (2015) · Circulation Research · doi:10.1161/circresaha.117.306044 · Cited by 144 · see citing works

Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires

Yang, Y., Wang, C., Yang, Q., Kantor, A. B., Chu, H., Ghosn, E., Guang, Q., Mazmanian, S. K., Han, J., & Herzenberg, L. A. (2015) · eLife · doi:10.7554/elife.09083 · Cited by 140 · see citing works

A Novel Mechanism of B Cell–Mediated Immune Suppression through CD73 Expression and Adenosine Production

Kaku, H., Cheng, K. F., Al‐Abed, Y., & Rothstein, T. L. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1400336 · Cited by 143 · see citing works

B Cell–Specific Loss of Lyn Kinase Leads to Autoimmunity

Lamagna, C., Hu, Y., DeFranco, A. L., & Lowell, C. A. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1301979 · Cited by 143 · see citing works

T cell-independent B cell memory

Defrance, T., Taillardet, M., & Genestier, L. (2011) · Current Opinion in Immunology · doi:10.1016/j.coi.2011.03.004 · Cited by 142 · see citing works

BTK Signaling in B Cell Differentiation and Autoimmunity

Corneth, O. B. J., Wolterink, R. G. J. K., & Hendriks, R. W. (2015) · Current topics in microbiology and immunology · doi:10.1007/82_2015_478 · Cited by 140 · see citing works

Plasma Cell Differentiation Pathways in Systemic Lupus Erythematosus

Malkiel, S., Barlev, A. N., Atisha‐Fregoso, Y., Suurmond, J., & Diamond, B. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00427 · Cited by 140 · see citing works

Chemical functionality of multidomain peptide hydrogels governs early host immune response

Lopez‐Silva, T. L., Leach, D. G., Azares, A. R., Li, I.-C., Woodside, D. G., & Hartgerink, J. D. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.119667 · Cited by 140 · see citing works

Ezh2 loss in hematopoietic stem cells predisposes mice to develop heterogeneous malignancies in an Ezh1-dependent manner

Mochizuki‐Kashio, M., Aoyama, K., Sashida, G., Oshima, M., Tomioka, T., Muto, T., Wang, C., & Iwama, A. (2015) · Blood · doi:10.1182/blood-2015-03-634428 · Cited by 141 · see citing works

Immunological Tolerance During Fetal Development

Mold, J. E., & McCune, J. M. (2012) · Advances in immunology · doi:10.1016/b978-0-12-394299-9.00003-5 · Cited by 138 · see citing works

Essential role of EBF1 in the generation and function of distinct mature B cell types

Vilagos, B., Hoffmann, M., Souabni, A., Sun, Q., Werner, B., Medvedovic, J., Bilić, I., Minnich, M., Axelsson, E., Jaritz, M., et al. (2012) · The Journal of Experimental Medicine · doi:10.1084/jem.20112422 · Cited by 138 · see citing works

Identification of IFN-γ-producing innate B cells

Bao, Y., Liu, X., Han, C., Xu, S., Xie, B., Zhang, Q., Gu, Y., Hou, J., Li, Q., Qian, C., et al. (2013) · Cell Research · doi:10.1038/cr.2013.155 · Cited by 138 · see citing works

Antigen receptor stereotypy in chronic lymphocytic leukemia

Σταματόπουλος, Κ., Agathangelidis, A., Rosenquist, R., & Ghia, P. (2016) · Leukemia · doi:10.1038/leu.2016.322 · Cited by 137 · see citing works

Autophagy in immunity

Zhou, S., & Zhang, H. (2012) · Autophagy · doi:10.4161/auto.21212 · Cited by 134 · see citing works

IgM autoantibodies to distinct apoptosis-associated antigens correlate with protection from cardiovascular events and renal disease in patients with SLE

Grönwall, C., Akhter, E., Oh, C., Burlingame, R. W., Petri, M., & Silverman, G. J. (2012) · Clinical Immunology · doi:10.1016/j.clim.2012.01.002 · Cited by 126 · see citing works

Defective immune responses in mice lacking LUBAC‐mediated linear ubiquitination in B cells

Sasaki, Y., Sano, S., Nakahara, M., Murata, S., Kometani, K., Aiba, Y., Sakamoto, S., Watanabe, Y., Tanaka, K., Kurosaki, T., et al. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.184 · Cited by 126 · see citing works

Mast cells as effector cells of innate immunity and regulators of adaptive immunity

Cardamone, C., Parente, R., Feo, G. D., & Triggiani, M. (2016) · Immunology Letters · doi:10.1016/j.imlet.2016.07.003 · Cited by 124 · see citing works

Protective Role for B-1b B Cells and IgM in Obesity-Associated Inflammation, Glucose Intolerance, and Insulin Resistance

Harmon, D. B., Srikakulapu, P., Kaplan, J. L., Oldham, S. N., McSkimming, C. C., Garmey, J. C., Perry, H. M., Kirby, J. L., Prohaska, T. A., Gonen, A., et al. (2016) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.116.307166 · Cited by 123 · see citing works

Artery Tertiary Lymphoid Organs Control Multilayered Territorialized Atherosclerosis B-Cell Responses in Aged ApoE −/− Mice

Srikakulapu, P., Hu, D., Yin, C., Mohanta, S. K., Bontha, S. V., Peng, L., Beer, M., Weber, C., McNamara, C. A., Grassia, G., et al. (2016) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.115.306983 · Cited by 120 · see citing works

Characterization of proposed human B-1 cells reveals pre-plasmablast phenotype

Covens, K., Verbinnen, B., Geukens, N., Meyts, I., Schuit, F. C., Lommel, L. V., Jacquemin, M. G., & Bossuyt, X. (2013) · Blood · doi:10.1182/blood-2012-12-471953 · Cited by 119 · see citing works

Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells

Kreslavsky, T., Vilagos, B., Tagoh, H., Kostanova‐Poliakova, D., Schwickert, T. A., Wöhner, M., Jaritz, M., Weiß, S., Taneja, R., Rossner, M. J., et al. (2017) · Nature Immunology · doi:10.1038/ni.3694 · Cited by 119 · see citing works

A human equivalent of mouse B-1 cells?

Descatoire, M., Weill, J., Reynaud, C., & Weller, S. (2011) · The Journal of Experimental Medicine · doi:10.1084/jem.20112232 · Cited by 119 · see citing works

Targeting B Cells in Atherosclerosis

Tsiantoulas, D., Sage, A. P., Mallat, Z., & Binder, C. J. (2014) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/atvbaha.114.303569 · Cited by 118 · see citing works

Role of Natural Autoantibodies and Natural IgM Anti-Leucocyte Autoantibodies in Health and Disease

Lobo, P. I. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00198 · Cited by 116 · see citing works

Current Understanding of Natural Antibodies and Exploring the Possibilities of Modulation Using Veterinary Models. A Review

Reyneveld, G. I., Savelkoul, H. F. J., & Parmentier, H. K. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.02139 · Cited by 116 · see citing works

IL-10–producing B cells are enriched in murine pericardial adipose tissues and ameliorate the outcome of acute myocardial infarction

Wu, L., Dalal, R., Cao, C. D., Postoak, J. L., Yang, G., Zhang, Q., Wang, Z., Lal, H., & Kaer, L. V. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1911464116 · Cited by 115 · see citing works

B1b Cells Recognize Protective Antigens after Natural Infection and Vaccination

Cunningham, A., Flores-Langarica, A., Bobat, S., Domínguez-Medina, C., Cook, C., Ross, E., López-Macías, C., & Henderson, I. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00535 · Cited by 59 · see citing works

Malondialdehyde Epitopes as Targets of Immunity and the Implications for Atherosclerosis

Papac-Miličević, N., Busch, C. J., & Binder, C. J. (2016) · Advances in immunology · doi:10.1016/bs.ai.2016.02.001 · Cited by 109 · see citing works

Heterogeneous plasma cells and long-lived subsets in response to immunization, autoantigen and microbiota

Liu, X., Yao, J., Zhao, Y., Wang, J., & Qi, H. (2022) · Nature Immunology · doi:10.1038/s41590-022-01345-5 · Cited by 108 · see citing works

B-cell targeted therapeutics in clinical development

Blüml, S., McKeever, K., Ettinger, R., Smolen, J. S., & Herbst, R. (2013) · Arthritis Research & Therapy · doi:10.1186/ar3906 · Cited by 112 · see citing works

B‐1a lymphocytes attenuate insulin resistance

Shen, L., Chng, M. H. Y., Alonso, M. N., Yuan, R., Winer, D. A., & Engleman, E. G. (2015) · Diabetes · doi:10.2337/db14-0554 · Cited by 109 · see citing works

B-1a lymphocytes promote oligodendrogenesis during brain development

Tanabe, S., & Yamashita, T. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0106-4 · Cited by 107 · see citing works

B-1 cell responses to infections

Smith, F. L., & Baumgarth, N. (2019) · Current Opinion in Immunology · doi:10.1016/j.coi.2018.12.001 · Cited by 107 · see citing works

Distinctions among Circulating Antibody-Secreting Cell Populations, Including B-1 Cells, in Human Adult Peripheral Blood

Quách, T. D., Rodríguez‐Zhurbenko, N., Hopkins, T. J., Guo, X., Hernández, A., Li, W., & Rothstein, T. L. (2016) · The Journal of Immunology · doi:10.4049/jimmunol.1501843 · Cited by 106 · see citing works

BCR-dependent lineage plasticity in mature B cells

Graf, R., Seagal, J., Otipoby, K. L., Lam, K., Ayoub, S., Zhang, B., Sander, S., Chu, V. T., & Rajewsky, K. (2019) · Science · doi:10.1126/science.aau8475 · Cited by 106 · see citing works

Development and function of tissue resident macrophages in mice

Kierdorf, K., Prinz, M., Geissmann, F., & Perdiguero, E. G. (2015) · Seminars in Immunology · doi:10.1016/j.smim.2016.03.017 · Cited by 106 · see citing works

B-1 Cell Heterogeneity and the Regulation of Natural and Antigen-Induced IgM Production

Baumgarth, N. (2016) · Frontiers in Immunology · doi:10.3389/fimmu.2016.00324 · Cited by 201 · see citing works

Inherent specificities in natural antibodies: a key to immune defense against pathogen invasion

Baumgarth, N., Tung, J. W., & Herzenberg, L. A. (2005) · Springer Seminars in Immunopathology · doi:10.1007/s00281-004-0182-2 · Cited by 545 · see citing works

B-1 cell responses to infections

Smith, F. L., & Baumgarth, N. (2019) · Current Opinion in Immunology · doi:10.1016/j.coi.2018.12.001 · Cited by 107 · see citing works

Natural and induced B‐1 cell immunity to infections raises questions of nature versus nurture

Baumgarth, N., Waffarn, E., & Nguyen, T. T. T. (2015) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.12804 · Cited by 46 · see citing works

Activation of B1 Cells

Catalán, D., & Ribeiro, C. H. (2025) · Elsevier eBooks · doi:10.1016/b978-0-12-824465-4.00234-9