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The Immune Underpinnings of Barrett’s-Associated Adenocarcinogenesis: a Retrial of Nefarious Immunologic Co-Conspirators

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Rubiarbonol B induces RIPK1-dependent necroptosis via NOX1-derived ROS production

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ADAM17 targeting by human cytomegalovirus remodels the cell surface proteome to simultaneously regulate multiple immune pathways

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Neuroprotection of Human Umbilical Cord-Derived Mesenchymal Stem Cells (hUC-MSCs) in Alleviating Ischemic Stroke-Induced Brain Injury by Regulating Inflammation and Oxidative Stress

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Anti-Inflammatory Effect of Dehydroxymethylepoxyquinomicin, a Nuclear factor–κB Inhibitor, on Endotoxin-Induced Uveitis in Rats In vivo and In vitro

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TNFR2 signaling modulates immunity after allogeneic hematopoietic cell transplantation

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CRISPR Screens to Identify Regulators of Tumor Immunity

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CRB2 enhances malignancy of glioblastoma via activation of the NF-κB pathway

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4β-Hydroxywithanolide E Modulates Alternative Splicing of Apoptotic Genes in Human Hepatocellular Carcinoma Huh-7 Cells

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TNFα induced up-regulation of Na+,K+,2Cl− cotransporter NKCC1 in hepatic ammonia clearance and cerebral ammonia toxicity

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Post-translational modification of the death receptor complex as a potential therapeutic target in cancer

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Selective regulation of a defined subset of inflammatory and immunoregulatory genes by an NF-κB p50–IκBζ pathwayPreprint

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Targeting the Nrf2/HO-1 aixs: A therapeutic strategy against regulated cell death in Alzheimer’s disease

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Polymorphisms of the TNF-α gene interact with plasma fatty acids on inflammatory biomarker profile: a population-based, cross-sectional study in São Paulo, Brazil

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Transition from TNF-Induced Inflammation to Death Signaling

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Melamine exposure from the weaning period causes apoptosis, inflammation, and damage to the blood-brain barrier

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ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genes

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Selective Induction of Cell Death in Human M1 Macrophages by Smac Mimetics Is Mediated by cIAP-2 and RIPK-1/3 through the Activation of mTORC

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Endothelial Caspase-8 prevents fatal necroptotic hemorrhage caused by commensal bacteria

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Endothelial RIPK1 protects artery bypass graft against arteriosclerosis by regulating SMC growth

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Modulation of extrinsic apoptotic pathway by intracellular glycosylation

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Immune Mechanisms Underlying Susceptibility to Endotoxin Shock in Aged Hosts: Implication in Age-Augmented Generalized Shwartzman Reaction

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Molecular Mechanisms of Cell Death

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Contribution of Mass Spectrometry-Based Proteomics to the Understanding of TNF-α Signaling

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Receptor-Interacting Protein Kinase 1 Promotes Cholangiocarcinoma Proliferation And Lymphangiogenesis Through The Activation Protein 1 Pathway

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Dysregulation of Cell Death in Human Chronic InflammationPreprint

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Functional Detection of TNF Receptor Family Members by Affinity-Labeled Ligands

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Isoliquiritigenin induces oxidative stress and immune response in zebrafish embryos

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Molecular basis for the recognition of 24-(S)-hydroxycholesterol by integrin αvβ3

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Vitamin D3 Partly Antagonizes Advanced-Glycation Endproducts-Induced NFκB Activation in Mouse Podocytes

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Impact of birth weight and neonatal nutritional interventions with micronutrients and bovine colostrum on the development of piglet immune response during the peri-weaning period

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The effect of inflammatory factors and their inhibitors on the hematopoietic stem cells fate

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Selective HSP90β inhibition results in TNF and TRAIL mediated HIF1α degradation

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The Compound (E)-2-Cyano-N,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases

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Immunometabolic actions of trabectedin and lurbinectedin on human macrophages: relevance for their anti-tumor activity

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B‐cell lymphoma‐2 family proteins in the crosshairs: Small molecule inhibitors and activators for cancer therapy

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Acute exposure to vibration is an apoptosis‐inducing stimulus in the vocal fold epithelium

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Ca2+-dependent hyperpolarization hypothesis for mammalian sleep

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Deubiquitinases A20 and CYLD modulate costimulatory signaling via CD137 (4–1BB)

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Cytokines as Mediators of Neuroinflammation in Experimental Autoimmune Encephalomyelitis

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Functional modulation of CD8+ T cell by approved novel immune enhancer: Nocardia rubra Cell-Wall Skeletons (Nr-CWS)

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Maintenance of Germinal Center B Cells by Caspase-9 through Promotion of Apoptosis and Inhibition of Necroptosis

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The Role of Cytokines and Inflammation in the Genesis of Experimental Pancreatitis.

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Carvacrol attenuated haloperidol-induced Parkinson’s disease via TNF/NFκβ-NLRP3-mediated pyroptosis

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Bushen Huoxue Formula Modulates Autophagic Flux and Inhibits Apoptosis to Protect Nucleus Pulposus Cells by Restoring the AMPK/SIRT1 Pathway

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The dichotomous outcomes of TNFα signaling in CD4+ T cells

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Mechanism of cell death and its application in the repair of inflammatory bowel disease by mesenchymal stem cells

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Smac mimetic induces an early wave of gene expression via NF-κB and AP-1 and a second wave via TNFR1 signaling

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Anti‑inflammatory effects of the NF‑κB inhibitor dehydroxymethylepoxyquinomicin on ARPE‑19 cells

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Anti-Inflammatory Activity and Mechanism of Hydrostatin-SN1 From Hydrophis cyanocinctus in Interleukin-10 Knockout Mice

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Could Antigen Presenting Cells Represent a Protective Element during SARS-CoV-2 Infection in Children?

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Cytokine TGF-β1, TNF-α, IFN-γ and IL‐6 Gene Polymorphisms and Localization of Premalignant Gastric Lesions in Immunohistochemically H. pylori-negative Patients

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Interactions Between Specific Immune Status of Pregnant Women and SARS-CoV-2 Infection

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Accelerated Discovery of Potent Bioactive anti‐TNFα Aptamers by Microbead‐Assisted Capillary Electrophoresis (MACE)‐SELEX

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Interleukin-10-Mediated Lymphopenia Caused by Acute Infection with Foot-and-Mouth Disease Virus in Mice

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Glycobiology of cellular expiry: Decrypting the role of glycan-lectin regulatory complex and therapeutic strategies focusing on cancer

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Antiulcerogenic Potential of the Ethanolic Extract of Ceiba speciosa (A. St.-Hil.) Ravenna Evaluated by In Vitro and In Vivo Studies

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Serum cytokine levels and other associated factors as possible immunotherapeutic targets and prognostic indicators for lung cancer

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Investigational systemic drugs for moderate to severe plaque psoriasis: What’s new?

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Polarity protein AF6 functions as a modulator of necroptosis by regulating ubiquitination of RIPK1 in liver diseases

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Interactome analysis of transforming growth factor-β-activated kinase 1 inHelicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37

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The Invasion Plasmid Antigen J (IpaJ) from Salmonella Inhibits NF-κB Activation by Suppressing IκBα Ubiquitination

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To catch a thief: regulated RIPK1 post-translational modifications as a fail-safe system to detect and overcome pathogen subversion of immune signaling

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Tumor Necrosis Factor Receptor-1 (p55) Deficiency Attenuates Tumor Growth and Intratumoral Angiogenesis and Stimulates CD8+ T Cell Function in Melanoma

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Cassia sieberiana DC. leaves modulate LPS-induced inflammatory response in THP-1 cells and inhibit eicosanoid-metabolizing enzymes

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Family with sequence similarity 83 member A promotes tumor cell proliferation and metastasis and predicts poor prognosis in cervical cancer

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TNFα-induced DLK activation contributes to apoptosis in the beta-cell line HIT

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Resveratrol decreases TNFα-induced ICAM-1 expression and release by Sirt-1-independent mechanism in intestinal myofibroblasts

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The comparative clinical efficacy of pyrophosphate/triclosan, copolymer/triclosan and zinc citrate/triclosan dentifrices for the reduction of supragingival calculus formation.

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Killing hepatocellular carcinoma in the NAFLD/NASH stage: a comprehensive perspective on targeting regulated cell death

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8-Geranylumbelliferone isolated from Paramignya trimera triggers RIPK1/RIPK3-dependent programmed cell death upon TNFR1 ligation

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Cleistocalyx nervosum var. paniala Berry Seed Protects against TNF-α-Stimulated Neuroinflammation by Inducing HO-1 and Suppressing NF-κB Mechanism in BV-2 Microglial Cells

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Establishment of the multi-component bone-on-a-chip: to explore therapeutic potential of DNA aptamers on endothelial cells

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Incoherent feedforward loop dominates the robustness and tunability of necroptosis biphasic, emergent, and coexistent dynamics

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A Comprehensive Network Pharmacology‐Based Strategy to Investigate Multiple Mechanisms of HeChan Tablet on Lung Cancer

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p38 and Casein Kinase 2 Mediate Ribonuclease 1 Repression in Inflamed Human Endothelial Cells via Promoter Remodeling Through Nucleosome Remodeling and Deacetylase Complex

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Smac-mimetics reduce numbers and viability of human osteoclasts

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Comparative proteomic analysis of spleen reveals key immune-related proteins in the yak (Bos grunniens) at different growth stages

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Downregulation of TNFR2 decreases survival gene expression, promotes apoptosis and affects the cell cycle of gastric cancer cells

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Computational study unravels inhibitory potential of epicatechin gallate against inflammatory and pyroptosis‐associated mediators in COVID‐19

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Therapeutic manipulation of host cell death pathways to facilitate clearance of persistent viral infections

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Repressive Control of Keratinocyte Cytoplasmic Inflammatory Signaling

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Reverse hierarchical DED assembly in the cFLIP-procaspase-8 and cFLIP-procaspase-8-FADD complexes

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Apoptotic signaling by TNFR1 is inhibited by the α2-6 sialylation, but not α2-3 sialylation, of the TNFR1 N-glycans

Hwang, J., Rao, T. C., Tao, J., Sha, B., Narimatsu, Y., Clausen, H., Mattheyses, A. L., & Bellis, S. L. (2024) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2024.108043 · Cited by 10

Radiation meets inflammation: NLRP3 inflammasome at the core of radiation-induced cardiac injury

Boncompagni, C., Giacovazzi, S., Perrone, M., Missiroli, S., Righes, G., Pinton, P., & Giorgi, C. (2025) · Journal of Translational Medicine · doi:10.1186/s12967-025-07377-3 · Cited by 10

Distinct Trypanosoma cruzi isolates induce activation and apoptosis of human neutrophils

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Activated human Foxp3+ regulatory T cells produce membrane-bound TNF

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Diagnosis and treatment of autoimmune retinopathy

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Role of TNF-α-induced m6A RNA methylation in diseases: a comprehensive review

Wang, Y., Liu, J., & Wang, Y. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1166308 · Cited by 10

Comparative transcriptome analysis reveals a serotype-specific immune response in Nile tilapia (Oreochromis niloticus) infected with Streptococcus agalactiae

Appel, R. J. C., Siqueira, K. N., Konstantinidis, I., Martins, M. I. M., Joshi, R., Pretto‐Giordano, L. G., Vilas-Bôas, L. A., & Fernandes, J. M. O. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1528721 · Cited by 10

Inflammatory cytokines provide both infection-responsive and developmental signals for blood development: Lessons from the zebrafish

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Absence of cytotoxicity towards microglia of iron oxide (α-Fe2O3) nanorhombohedra

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PKC-ѳ is dispensable for OX40L-induced TCR-independent Treg proliferation but contributes by enabling IL-2 production from effector T-cells

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Co‐infection with distinct Trypanosoma cruzi strains induces an activated immune response in human monocytes

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Cyst Reduction in a Polycystic Kidney Disease Drosophila Model Using Smac Mimics

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New insights on the interaction mechanism of rhTNFα with its antagonists Adalimumab and Etanercept

Contreras, M. A., Macaya, L., Neira, P., Camacho, F., González, A., Acosta, J., Montesino, R., Toledo, J. R., & Sánchez, O. (2020) · Biochemical Journal · doi:10.1042/bcj20200568 · Cited by 10

COX2 confers bone marrow stromal cells to promoting TNFα/TNFR1β-mediated myeloma cell growth and adhesion

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Targeting sTNF/TNFR1 Signaling as a New Therapeutic Strategy

Fischer, R., Kontermann, R. E., & Maier, O. (2015) · Antibodies · doi:10.3390/antib4010048 · Cited by 90

Death by TNF: a road to inflammation

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Tumor Necrosis Factor Signaling Pathways

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The Balance of TNF Mediated Pathways Regulates Inflammatory Cell Death Signaling in Healthy and Diseased Tissues

Webster, J. D., & Vucic, D. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00365 · Cited by 324

Tumour necrosis factor (TNF) receptor family (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

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