The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
A means to a DNA end: the many roles of Ku
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
Martin, S. G., Laroche, T., Suka, N., Grunstein, M., & Gasser, S. M. (1999) · Cell · doi:10.1016/s0092-8674(00)80773-4 · Cited by 464
DNA double strand break repair and chromosomal translocation: Lessons from animal models
Ferguson, D. O., & Alt, F. W. (2001) · Oncogene · doi:10.1038/sj.onc.1204767 · Cited by 333
DNA end-joining catalyzed by human cell-free extracts
Baumann, P., & West, S. C. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.24.14066 · Cited by 295
DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p
McAinsh, A. D., Scott-Drew, S., Murray, J. A. H., & Jackson, S. P. (1999) · Current Biology · doi:10.1016/s0960-9822(99)80424-2 · Cited by 115
Self-citation
Cited by
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
Lieber, M. R. (2010) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.052308.093131 · Cited by 2,882
The mechanism of human nonhomologous DNA end joining
Lieber, M. R. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.r700039200 · Cited by 720
Positional stability of single double-strand breaks in mammalian cells
Soutoglou, E., Dorn, J. F., Sengupta, K., Jasin, M., Nussenzweig, A., Ried, T., Danuser, G., & Misteli, T. (2007) · Nature Cell Biology · doi:10.1038/ncb1591 · Cited by 509
Chromatin Higher-order Structure and Dynamics
Woodcock, C. L., & Ghosh, R. P. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000596 · Cited by 384
Functional links between telomeres and proteins of the DNA-damage response
d'Adda di Fagagna, F., Teo, S.-H., & Jackson, S. P. (2004) · Genes & Development · doi:10.1101/gad.1214504 · Cited by 277
Self-citationChronic Obstructive Pulmonary Disease and Lung Cancer: New Molecular Insights
Adcock, I. M., Caramori, G., & Barnes, P. J. (2011) · Respiration · doi:10.1159/000324601 · Cited by 257
Do DNA Double-Strand Breaks Drive Aging?
White, R. R., & Vijg, J. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.08.004 · Cited by 232
Unbalanced oxidant-induced DNA damage and repair in COPD: a link towards lung cancer
Caramori, G., Adcock, I. M., Casolari, P., Ito, K., Jazrawi, E., Tsaprouni, L., Villetti, G., Civelli, M., Carnini, C., Chung, K. F., et al. (2011) · Thorax · doi:10.1136/thx.2010.156448 · Cited by 187
Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides
Gomez, J. A., Gama, V., Yoshida, T., Sun, W., Hayes, P., Leskov, K., Boothman, D., & Matsuyama, S. (2007) · Biochemical Society Transactions · doi:10.1042/bst0350797 · Cited by 97
Limiting the Persistence of a Chromosome Break Diminishes Its Mutagenic Potential
Bennardo, N., Gunn, A., Cheng, A., Hasty, P., & Stark, J. M. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000683 · Cited by 82
Transient ATM Kinase Inhibition Disrupts DNA Damage–Induced Sister Chromatid Exchange
White, J. S., Choi, S., & Bakkenist, C. J. (2010) · Science Signaling · doi:10.1126/scisignal.2000758 · Cited by 66
The end protection problem—an unexpected twist in the tail
Ruis, P., & Boulton, S. J. (2021) · Genes & Development · doi:10.1101/gad.344044.120 · Cited by 57
Gama, V, Gomez, J. A., Mayo, L. D., Jackson, M. W., Danielpour, D., Song, K., Haas, A. L., Laughlin, M. J., & Matsuyama, S. (2009) · Cell Death & Differentiation · doi:10.1038/cdd.2009.6 · Cited by 46
Coordination of DNA-PK activation and nuclease processing of DNA termini in NHEJ
Pawelczak, K. S., Bennett, S. M., & Turchi, J. J. (2011) · Antioxidants & Redox Signaling · doi:10.1089/ars.2010.3368 · Cited by 33
C-terminal low-complexity sequence repeats of Mycobacterium smegmatis Ku modulate DNA binding
Kushwaha, A. K., & Grove, A. (2013) · Bioscience Reports · doi:10.1042/bsr20120105 · Cited by 30
Tarry-Adkins, J. L., Aiken, C. E., Ashmore, T. J., & Ozanne, S. E. (2018) · Scientific Reports · doi:10.1038/s41598-018-22383-w · Cited by 13
Metadata
- Authors
- Downs, J. A., & Jackson, S. P.
- Venue
- Nature Reviews Molecular Cell Biology
- Published
- 2004-05
- Volume
- 5
- Issue
- 5
- Pages
- 367-378
- ISSN
- 1471-0072 (ISSN-L)
- 1471-0080
- OpenAlex
- W2008181290
- Cited by
- 395
- References
- 4
- FWCI
- 1.35
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.