Ras oncogenes: split personalities

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Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

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Creation of human tumour cells with defined genetic elements

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Phosphatidylinositol-3-OH kinase direct target of Ras

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Mammalian Ras interacts directly with the serine/threonine kinase raf

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Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome

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The Ras-RasGAP Complex: Structural Basis for GTPase Activation and Its Loss in Oncogenic Ras Mutants

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Type 1 Neurofibromatosis Gene: Identification of a Large Transcript Disrupted in Three NF1 Patients

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Mechanism of activation of a human oncogene

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A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene

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DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA

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RAF/RAS oncogenes and mismatch-repair status

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A Cytoplasmic Protein Stimulates Normal N- ras p21 GTPase, But Does Not Affect Oncogenic Mutants

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Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

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The neurofibromatosis type 1 gene encodes a protein related to GAP

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Increasing complexity of Ras signaling

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Molecular Switch for Signal Transduction: Structural Differences Between Active and Inactive Forms of Protooncogenic ras Proteins

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Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras

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A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3‐OH kinase and protein kinase B/Akt cellular survival pathway

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Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane

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The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

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Complete nucleotide sequences of the T24 human bladder carcinoma oncogene and its normal homologue

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The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21

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Activation of Raf as a Result of Recruitment to the Plasma Membrane

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Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

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Complexes of Ras⋅GTP with Raf-1 and Mitogen-Activated Protein Kinase Kinase

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Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene

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Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

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ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

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K- and N-Ras Are Geranylgeranylated in Cells Treated with Farnesyl Protein Transferase Inhibitors

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An Acylation Cycle Regulates Localization and Activity of Palmitoylated Ras Isoforms

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Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1

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Reactive Oxygen Species-Induced Activation of the MAP Kinase Signaling Pathways

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Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects

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Endomembrane Trafficking of Ras

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Reovirus Therapy of Tumors with Activated Ras Pathway

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Germline KRAS mutations cause Noonan syndrome

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Germline Mutations in Genes Within the MAPK Pathway Cause Cardio-facio-cutaneous Syndrome

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The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus

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Normal Human Fibroblasts Are Resistant to RAS-Induced Senescence

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