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NAMPT and NAPRT: Two Metabolic Enzymes With Key Roles in Inflammation

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Role of Redox Status in Development of Glioblastoma

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Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin‐resistant men

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Trigonelline Is an NAD+ Precursor That Improves Muscle Function during Ageing and Is Reduced in Human Sarcopenia

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Targeting NAD+ in Metabolic Disease: New Insights Into an Old Molecule

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NAMPT as a Therapeutic Target against Stroke

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Who watches the watchmen? Regulation of the expression and activity of sirtuins

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NAD+ as the Link Between Oxidative Stress, Inflammation, Caloric Restriction, Exercise, DNA Repair, Longevity, and Health Span

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Nicotinamide riboside, a form of vitamin B3 and NAD+ precursor, relieves the nociceptive and aversive dimensions of paclitaxel-induced peripheral neuropathy in female rats

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NAMPT: A critical driver and therapeutic target for cancer

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Gulf War Illness: Mechanisms Underlying Brain Dysfunction and Promising Therapeutic Strategies

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Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation

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Antitumor effect of combined NAMPT and CD73 inhibition in an ovarian cancer model

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Extranuclear Sirtuins and Metabolic Stress

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NAD-Biosynthetic and Consuming Enzymes as Central Players of Metabolic Regulation of Innate and Adaptive Immune Responses in Cancer

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Nicotinamide Phosphoribosyltransferase (NAMPT) as a Therapeutic Target in BRAF-Mutated Metastatic Melanoma

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Dual-target inhibitors of poly (ADP-ribose) polymerase-1 for cancer therapy: Advances, challenges, and opportunities

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Enzymology of extracellular NAD metabolism

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Use of Metabolomics to Trend Recovery and Therapy After Injury in Critically Ill Trauma Patients

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Nicotinamide Phosphoribosyltransferase as a Key Molecule of the Aging/Senescence Process

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NAD+ Metabolism and Immune Regulation: New Approaches to Inflammatory Bowel Disease Therapies

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Mitochondrial Dysfunction in Cardiovascular Aging

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Poly(ADP-ribose) polymerase 1 is a novel target to promote axonal regeneration

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NAD+ Metabolism Regulates Preadipocyte Differentiation by Enhancing α-Ketoglutarate-Mediated Histone H3K9 Demethylation at the PPARγ Promoter

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Peroxisome biogenesis in mammalian cells: The impact of genes and environment

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The Extracellular NADome Modulates Immune Responses

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The key role of the NAD biosynthetic enzyme nicotinamide mononucleotide adenylyltransferase in regulating cell functions

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Targeting sirtuin activity with nicotinamide riboside reduces neuroinflammation in a GWI mouse model

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NAMPT and NAMPT-controlled NAD Metabolism in Vascular Repair

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Extracellular nicotinamide phosphoribosyltransferase (eNAMPT) is a novel marker for patients with BRAF-mutated metastatic melanoma

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Nicotinamide phosphoribosyltransferase‑related signaling pathway in early Alzheimer's disease mouse models

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Rubella Viruses Shift Cellular Bioenergetics to a More Oxidative and Glycolytic Phenotype with a Strain-Specific Requirement for Glutamine

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Comparative Metabolomic Profiling Reveals That Dysregulated Glycolysis Stemming from Lack of Salvage NAD+ Biosynthesis Impairs Reproductive Development in Caenorhabditis elegans

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Regulation of Cancer and Cancer-Related Genes via NAD +

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Synthesis and Degradation of Adenosine 5′-Tetraphosphate by Nicotinamide and Nicotinate Phosphoribosyltransferases

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Embryonic response to high beta-hydroxybutyrate (BHB) levels in postpartum dairy cows

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Fusobacterium nucleatum promotes the development of acute liver failure by inhibiting the NAD+ salvage metabolic pathway

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A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D‐2‐hydroxyglutaric aciduria type II mouse model

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Simultaneous quantification of nicotinamide mononucleotide and related pyridine compounds in mouse tissues by UHPLC–MS/MS

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NAD+ metabolism in peripheral neuropathic pain

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NAD+ Therapeutics and Skeletal Muscle Adaptation to Exercise in Humans

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Structure based pharmacophore study to identify possible natural selective PARP-1 trapper as anti-cancer agent

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The Interactome between Metabolism and Gene Mutations in Myeloid Malignancies

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Characterization and mutational analysis of a nicotinamide mononucleotide deamidase from Agrobacterium tumefaciens showing high thermal stability and catalytic efficiency

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Role of NAD+ and FAD in Ischemic Stroke Pathophysiology: An Epigenetic Nexus and Expanding Therapeutic Repertoire

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A comprehensive comparison of the metazoan tryptophan degrading enzymes

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Exploratory study on the occurrence and dynamics of yeast-mediated nicotinamide riboside production in craft beers

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NAD+ Kinase Enzymes Are Reversible, and NAD+ Product Inhibition Is Responsible for the Observed Irreversibility of the Human Enzyme

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Targeting Metabolic and pH Regulatory Pathways in Cancer via Dual Inhibition of Nicotinamide Phosphoribosyltransferase and Carbonic Anhydrases IX and XII

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A Versatile Continuous Fluorometric Enzymatic Assay for Targeting Nicotinate Phosphoribosyltransferase

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Dual Roles of Nicotinamide Phosphoribosyltransferase as a Promising Target for Cancer Radiotherapy

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A molecular circuit linking the BCR to the NAD biosynthetic enzyme NAMPT is an actionable target in Richter syndrome

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Periplasmic binding proteins Bug69 and Bug27 from Bordetella pertussis are in vitro high‐affinity quinolinate binders with a potential role in NAD biosynthesis

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Cardiomyocyte Differentiation Promotes Cell Survival During Nicotinamide Phosphoribosyltransferase Inhibition Through Increased Maintenance of Cellular Energy Stores

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Visfatin serum concentration and hepatic mRNA expression in chronic hepatitis C

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NAD Metabolism and Proteomic Profile in a Yeast Model Expressing a Neurotoxic polyQ Protein: Effect of Phenolics from Extra-virgin Olive OilPreprint

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Special Issue on “Cofactor-dependent proteins: Evolution, chemical diversity and bio-applications”

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Sviluppo di un metodo enzimatico di analisi per la discriminazione delle vie di utilizzo della vitamina B3 in differenti condizioni metaboliche

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Food Quality and Functionality

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Fusobacterium Nucleatum Promotes the Development of Acute Liver Failure by Inhibiting the NAD+ Salvage Metabolic PathwayPreprint

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Fusobacterium Nucleatum Promotes the Development of Acute Liver Failure by Inhibiting the NAD + Salvage Metabolic PathwayPreprint

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A DECLINE IN VITAMIN K AND SOD LEVELS AND THE CHANGE IN PARP1 AND SIRT1 EXPRESSION MIGHT BE ASSOCIATED WITH PROGRESSION OF BREAST CANCER

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The AsnC family regulator VU14_03665 modulates antibiotic resistance and acid tolerance in Aeromonas hydrophila AH10

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Coffee and coffee-derived bioactive compounds in skeletal muscle health: a scoping review of mechanistic pathways, preclinical evidence and human outcomes

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BindingDB Entry 50000368: α-Amino-β-carboxymuconate-ε-semialdehyde Decarboxylase (ACMSD) Inhibitors as Novel Modulators of De Novo Nicotinamide Adenine Dinucleotide (NAD

BindingDB (2019) · UC San Diego · doi:10.7270/q22j6f80

BindingDB Entry 50016864: Dual-target inhibitors of poly (ADP-ribose) polymerase-1 for cancer therapy: Advances, challenges, and opportunities.

BindingDB (2023) · UC San Diego · doi:10.7270/q29p35pg

NAD Biosynthesis in Humans - Enzymes, Metabolites and Therapeutic Aspects

Dölle, C., Skoge, R. H., VanLinden, M. R., & Ziegler, M. (2013) · Current Topics in Medicinal Chemistry · doi:10.2174/15680266113136660206 · Cited by 78 · see citing works

The Regulatory Role of NAD in Human and Animal Cells

Kulikova, V., Gromyko, D. V., & Nikiforov, A. A. (2018) · Biochemistry (Moscow) · doi:10.1134/s0006297918070040 · Cited by 34 · see citing works

NAD+ as a Signaling Molecule Modulating MetabolismPreprint

Cantó, C., & Auwerx, J. H. (2011) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.2012.76.010439 · Cited by 109 · see citing works

Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio

Anderson, K. A., Madsen, A. S., Olsen, C. A., & Hirschey, M. D. (2017) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2017.09.005 · Cited by 210 · see citing works

The human NAD metabolome: Functions, metabolism and compartmentalization

Nikiforov, A. A., Kulikova, V., & Ziegler, M. (2015) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2015.1028612 · Cited by 214 · see citing works