Structural vaccinology starts to deliver

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Reverse vaccinology

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Influenza Virus Vaccine Based on the Conserved Hemagglutinin Stalk Domain

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Pili in Gram-positive pathogens

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Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

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Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing Epitopes

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Structure of the parainfluenza virus 5 F protein in its metastable, prefusion conformation

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Group A Streptococcus produce pilus-like structures containing protective antigens and Lancefield T antigens

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Vaccination against Neisseria meningitidis Using Three Variants of the Lipoprotein GNA1870

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Vaccines for the twenty-first century society

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Respiratory Syncytial Virus-associated Hospitalizations Among Infants and Young Children in the United States, 1997–2006

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Vaccine Potential of theNeisseria meningitidis2086 Lipoprotein

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Genome Analysis Reveals Pili in Group B Streptococcus

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Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates

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Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein

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Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

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Neutralizing antibodies against the preactive form of respiratory syncytial virus fusion protein offer unique possibilities for clinical intervention

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Structural and genetic basis for development of broadly neutralizing influenza antibodies

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Preventing Bacterial Infections with Pilus-Based Vaccines: the Group B Streptococcus Paradigm

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Broad vaccine coverage predicted for a bivalent recombinant factor H binding protein based vaccine to prevent serogroup B meningococcal disease

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Structural basis of respiratory syncytial virus neutralization by motavizumab

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Structure-based antigen design: a strategy for next generation vaccines

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The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenuated, respiratory syncytial virus vaccines

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Level of Maternal IgG Anti–Group B Streptococcus Type III Antibody Correlated with Protection of Neonates against Early‐Onset Disease Caused by This Pathogen

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Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections

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Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity

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A Meningococcal Factor H Binding Protein Mutant That Eliminates Factor H Binding Enhances Protective Antibody Responses to Vaccination

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Structure of a Major Antigenic Site on the Respiratory Syncytial Virus Fusion Glycoprotein in Complex with Neutralizing Antibody 101F

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Efficacious Recombinant Influenza Vaccines Produced by High Yield Bacterial Expression: A Solution to Global Pandemic and Seasonal Needs

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Electron Microscopy of the Human Respiratory Syncytial Virus Fusion Protein and Complexes That It Forms with Monoclonal Antibodies

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Design and Characterization of Epitope-Scaffold Immunogens That Present the Motavizumab Epitope from Respiratory Syncytial Virus

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Immunogenicity of a new purified fusion protein vaccine to respiratory syncytial virus: a multi-center trial in children with cystic fibrosis

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Immunogenicity and Efficacy of Flagellin-Fused Vaccine Candidates Targeting 2009 Pandemic H1N1 Influenza in Mice

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Structural Basis for the Immunogenic Properties of the Meningococcal Vaccine Candidate LP2086

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Bactericidal Antibody Responses Induced by Meningococcal Recombinant Chimeric Factor H-Binding Protein Vaccines

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Complement-Mediated Bactericidal Activity of Anti-Factor H Binding Protein Monoclonal Antibodies against the Meningococcus Relies upon Blocking Factor H Binding

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Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen of Neisseria meningitidis

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Design and Evaluation of Meningococcal Vaccines through Structure-Based Modification of Host and Pathogen Molecules

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A dose-ranging study of a subunit Respiratory Syncytial Virus subtype A vaccine with and without aluminum phosphate adjuvantation in adults ≥65 years of age

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Conformational constraints of conserved neutralizing epitopes from a major antigenic area of human respiratory syncytial virus fusion glycoprotein

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Epitope Mapping of a Bactericidal Monoclonal Antibody against the Factor H Binding Protein of Neisseria meningitidis

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Design of Meningococcal Factor H Binding Protein Mutant Vaccines That Do Not Bind Human Complement Factor H

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Conformational studies of a short linear peptide corresponding to a major conserved neutralizing epitope of human respiratory syncytial virus fusion glycoprotein

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Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

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Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design

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Outer membrane vesicles as platform vaccine technology

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Self-assembling protein nanoparticles in the design of vaccines

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Adjuvanted influenza vaccines

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Structure-Based Vaccine Antigen Design

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Chemical Biology Approaches to Designing Defined Carbohydrate Vaccines

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New Routes and Opportunities for Modular Construction of Particulate Vaccines: Stick, Click, and Glue

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Intranasal and oral vaccination with protein-based antigens: advantages, challenges and formulation strategies

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Self-replicating alphavirus RNA vaccines

Ljungberg, K., & Liljeström, P. (2014) · Expert Review of Vaccines · doi:10.1586/14760584.2015.965690 · Cited by 137 · see citing works

Vaccinomics, adversomics, and the immune response network theory: Individualized vaccinology in the 21st century

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Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines

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Designing Vaccines for the Twenty-First Century Society

Finco, O., & Rappuoli, R. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00012 · Cited by 117 · see citing works

RNA Virus Reverse Genetics and Vaccine Design

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Designing an efficient multi-epitope oral vaccine against Helicobacter pylori using immunoinformatics and structural vaccinology approaches

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Genome sequencing of rumen bacteria and archaea and its application to methane mitigation strategies.

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Advances in structure-based vaccine design

Kulp, D. W., & Schief, W. R. (2013) · Current Opinion in Virology · doi:10.1016/j.coviro.2013.05.010 · Cited by 106 · see citing works

Variation of the Specificity of the Human Antibody Responses after Tick-Borne Encephalitis Virus Infection and Vaccination

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Broadly neutralizing epitopes in the Plasmodium vivax vaccine candidate Duffy Binding Protein

Chen, E., Salinas, N. D., Huang, Y., Ntumngia, F. B., Plasencia, M. D., Gross, M. L., Adams, J. H., & Tolia, N. H. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1600488113 · Cited by 88 · see citing works

Dissection of Antibody Specificities Induced by Yellow Fever Vaccination

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Computational Methods in Immunology and Vaccinology: Design and Development of Antibodies and Immunogens

Guarra, F., & Colombo, G. (2023) · Journal of Chemical Theory and Computation · doi:10.1021/acs.jctc.3c00513 · Cited by 79 · see citing works

Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody

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A human monoclonal antibody blocks malaria transmission and defines a highly conserved neutralizing epitope on gametes

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Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption

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Discovery of Novel Leptospirosis Vaccine Candidates Using Reverse and Structural Vaccinology

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Platform technologies for modern vaccine manufacturing

Charlton, H. K., & Lua, L. H. L. (2017) · Vaccine · doi:10.1016/j.vaccine.2017.02.069 · Cited by 62 · see citing works

The promise of reverse vaccinology

Heinson, A., Woelk, C. H., & Newell, M. (2015) · International Health · doi:10.1093/inthealth/ihv002 · Cited by 61 · see citing works

Protein Crystallography in Vaccine Research and Development

Malito, E., Carfı́, A., & Bottomley, M. J. (2015) · International Journal of Molecular Sciences · doi:10.3390/ijms160613106 · Cited by 61 · see citing works

In silico design of an immunogen against Acinetobacter baumannii based on a novel model for native structure of Outer membrane protein A

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Physicochemical and functional characterization of vaccine antigens and adjuvants

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