Cited by 388Immune responses and vaccinationsImmunotherapy and Immune ResponsesVaccine Coverage and Hesitancy

Vaccines for the twenty-first century society

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Rappuoli, Rino, Mandl, Christian W., Black, Steven, De Gregorio, Ennio·2011·Nature Reviews Immunology

Abstract

Vaccines have been one of the major revolutions in the history of mankind and, during the twentieth century, they eliminated most of the childhood diseases that used to cause millions of deaths. In the twenty-first century, vaccines will also play a major part in safeguarding people's health. Supported by the innovations derived from new technologies, vaccines will address the new needs of a twenty-first century society characterized by increased life expectancy, emerging infections and poverty in low-income countries.

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  • New technologies will be required to address changing vaccine needs.

    “However, with increasing life expectancy in high-income countries and newly emerging infections and poverty in low-income countries, new technologies will be required to address changing vaccine needs (1).”

    From Nonviral delivery of self-amplifying RNA vaccines (2012) · cites this paper as [1]

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Research works printed but not linked: 2

  1. [7]Centers for Disease Control and Prevention. Notes from the Field: Pertussis --- California, January--June 2010. Morb. Mortal. Wkly Rep.59, 817 (2010).
  2. [21]HHS pandemic influenza implementation plan. Chapter 5: vaccines. United States Department of Human & Health Services [online] (2006).

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Authors
Rappuoli, R., Mandl, C. W., Black, S., & De Gregorio, E.
Affiliations
  • Novartis (Italy) (IT)
  • Cincinnati Children's Hospital Medical Center (US)
Corresponding author
Rappuoli, Rino
Venue
Nature Reviews Immunology
Published
2011-11-04
Volume
11
Issue
12
Pages
865-872
ISSN
  • 1474-1733 (ISSN-L)
  • 1474-1741
OpenAlex
W1976948056
Cited by
388
References
25
Citations by year
2026: 11 · 2025: 15 · 2024: 16 · 2023: 24 · 2022: 30 · 2021: 24 · 2020: 27 · 2019: 32 · 2018: 20 · 2017: 27 · 2016: 32 · 2015: 36 · 2014: 35 · 2013: 32 · 2012: 26
FWCI
2.67
Type
journal article
Language
en
Update notices
erratum (2012-01-30)
Open access
Locations
  • Nature reviews. Immunology (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
  • Life Sciences › Immunology and Microbiology › Immunology › Immunotherapy and Immune Responses
  • Social Sciences › Health › Vaccine Coverage and Hesitancy
Keywords
vaccines, vaccine development, childhood immunization, emerging infectious diseases, low-income countries, poverty, life expectancy
MeSH terms
Adolescent, Adult, Age Factors, Aged, Aged, 80 and over, Child, Child, Preschool, Developing Countries, Female, Forecasting, Humans, Infant, Infant, Newborn, Life Expectancy, Male, Middle Aged, Poverty, Pregnancy, Vaccination, Vaccines, Infection Control, Immunization Programs, Communicable Diseases, Emerging, Vulnerable Populations, Young Adult

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