The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Membrane fusion
Open accessAbstract
Subcellular compartmentalization, cell growth, hormone secretion and neurotransmission require rapid, targeted, and regulated membrane fusion. Fusion entails extensive lipid rearrangements by two apposed (docked) membrane vesicles, joining their membrane proteins and lipids and mixing their luminal contents without lysis. Fusion of membranes in the secretory pathway involves Rab GTPases; their bound 'effector' proteins, which mediate downstream steps; SNARE proteins, which can 'snare' each other, in cis (bound to one membrane) or in trans (anchored to apposed membranes); and SNARE-associated proteins (SM proteins; NSF or Sec18p; SNAP or Sec17p; and others) cooperating with specific lipids to catalyze fusion. In contrast, mitochondrial and cell-cell fusion events are regulated by and use distinct catalysts.
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Cites
Südhof, T. C. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131412 · Cited by 2,547
Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 Å resolution
Sutton, R. B., Fasshauer, D., Jahn, R., & Brunger, A. T. (1998) · Nature · doi:10.1038/26412 · Cited by 2,417
Rabs and their effectors: achieving specificity in membrane traffic
Grosshans, B. L., Ortiz, D., & Novick, P. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0601617103 · Cited by 1,005
The Rab5 effector EEA1 is a core component of endosome docking
Christoforidis, S., McBride, H. M., Burgoyne, R. D., & Zerial, M. (1999) · Nature · doi:10.1038/17618 · Cited by 854
McBride, H. M., Rybin, V., Murphy, C., Giner, A., Teasdale, R., & Zerial, M. (1999) · Cell · doi:10.1016/s0092-8674(00)81966-2 · Cited by 520
Wurmser, A. E., Sato, T. K., & Emr, S. D. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.151.3.551 · Cited by 425
Cited by
Chernomordik, L. V., & Kozlov, M. M. (2008) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1455 · Cited by 1,037
Rab Proteins and the Compartmentalization of the Endosomal System
Wandinger-Ness, A., & Zerial, M. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a022616 · Cited by 586
Architecture of the synaptotagmin–SNARE machinery for neuronal exocytosis
Zhou, Q., Lai, Y., Bacaj, T., Zhao, M., Lyubimov, A. Y., Uervirojnangkoorn, M., Zeldin, O. B., Brewster, A. S., Sauter, N. K., Cohen, A. E., et al. (2015) · Nature · doi:10.1038/nature14975 · Cited by 348
Lőrincz, P., & Juhász, G. (2020) · Journal of Molecular Biology · doi:10.1016/j.jmb.2019.10.028 · Cited by 328
Wang, Z., Miao, G., Xue, X., Guo, X., Yuan, C., Wang, Z., Zhang, G., Chen, Y., Feng, D., Hu, J., et al. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.08.021 · Cited by 321
Mechanisms of SNARE proteins in membrane fusion
Jahn, R., Cafiso, D. C., & Tamm, L. K. (2024) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-023-00668-x · Cited by 248
Endocytosis and Autophagy: Exploitation or Cooperation?
Tooze, S. A., Abada, A., & Elazar, Z. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a018358 · Cited by 202
Cellular Uptake and Intracellular Trafficking of Antisense and siRNA Oligonucleotides
Juliano, R. L., Ming, X., & Nakagawa, O. (2012) · Bioconjugate Chemistry · doi:10.1021/bc200377d · Cited by 181
Retromer mediates a discrete route of local membrane delivery to dendrites
Choy, R. W.-Y., Park, M., Temkin, P., Herring, B. E., Marley, A., Nicoll, R. A., & von Zastrow, M. (2014) · Neuron · doi:10.1016/j.neuron.2014.02.018 · Cited by 135
Free energies of membrane stalk formation from a lipidomics perspective
Poojari, C. S., Scherer, K. C., & Hub, J. S. (2021) · Nature Communications · doi:10.1038/s41467-021-26924-2 · Cited by 98
A secretagogin locus of the mammalian hypothalamus controls stress hormone release
Romanov, R. A., Alpár, A., Zhang, M., Zeisel, A., Calas, A., Landry, M., Fuszard, M., Shirran, S. L., Schnell, R., Dobolyi, Á., et al. (2015) · The EMBO Journal · doi:10.15252/embj.201488977 · Cited by 85
Ryder, P. V., Vistein, R., Gokhale, A., Seaman, M. N., Puthenveedu, M. A., & Faundez, V. (2013) · Molecular Biology of the Cell · doi:10.1091/mbc.e13-02-0088 · Cited by 87
Johansson, J. U., Ericsson, J., Janson, J., Beraki, S., Stanić, D., Mandic, S. A., Wikström, M. A., Hökfelt, T., Ögren, S. O., Rozell, B., et al. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000278 · Cited by 83
RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis
Gulbranson, D. R., Davis, E. M., Demmitt, B. A., Ouyang, Y., Ye, Y., Yu, H., & Shen, J. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1712176114 · Cited by 67
Regulation of plasma membrane expansion during axon formation
Quiroga, S., Bisbal, M., & Cáceres, A. (2018) · Developmental Neurobiology · doi:10.1002/dneu.22553 · Cited by 31
Lai, Y., Lou, X., Jho, Y., Yoon, T.-Y., & Shin, Y.-K. (2013) · Biochemical Journal · doi:10.1042/bj20130949 · Cited by 28
SNARE disassembly requires Sec18/NSF side loading
(2025) · doi:10.1038/s41594-025-01590-w · Cited by 9
Regulation of vacuole fusion in stomata by dephosphorylation of the HOPS subunit VPS39
Pullen, A., Billings, G., Hodgens, C., White, G., Akpa, B. S., & Rojas‐Pierce, M. (2025) · The Plant Journal · doi:10.1111/tpj.70640 · Cited by 1
Metadata
- Authors
- Wickner, W., & Schekman, R.
- Venue
- Nature Structural & Molecular Biology
- Published
- 2008-07
- Volume
- 15
- Issue
- 7
- Pages
- 658-664
- ISSN
- 1545-9985 (ISSN-L)
- 1545-9993
- OpenAlex
- W4211197456
- Cited by
- 435
- References
- 6
- FWCI
- 13.14
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
