The DOI matches its Crossref record; 152 of the 152 references it cites were found in a registry or an index.
Perceiving the epigenetic landscape through histone readers
Open accessAbstract
Post-translational modifications (PTMs) of histones provide a fine-tuned mechanism for regulating chromatin structure and dynamics. PTMs can alter direct interactions between histones and DNA and serve as docking sites for protein effectors, or readers, of these PTMs. Binding of the readers recruits or stabilizes various components of the nuclear signaling machinery at specific genomic sites, mediating fundamental DNA-templated processes, including gene transcription and DNA recombination, replication and repair. In this review, we highlight the latest advances in characterizing histone-binding mechanisms and identifying new epigenetic readers and summarize the functional significance of PTM recognition.
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Citations
Cites
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Cited by
Histone core modifications regulating nucleosome structure and dynamics
Tessarz, P., & Kouzarides, T. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3890 · Cited by 1,018
Interplay between the Cancer Genome and Epigenome
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Transcriptional regulation by Polycomb group proteins
Di Croce, L., & Helin, K. (2013) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.2669 · Cited by 864
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Rothbart, S. B., & Strahl, B. D. (2014) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2014.03.001 · Cited by 720
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Metadata
- Authors
- Musselman, C. A., Lalonde, M.-E., Côté, J., & Kutateladze, T. G.
- Venue
- Nature Structural & Molecular Biology
- Published
- 2012-12
- Volume
- 19
- Issue
- 12
- Pages
- 1218-1227
- ISSN
- 1545-9985 (ISSN-L)
- 1545-9993
- OpenAlex
- W2038235796
- Cited by
- 833
- References
- 152
- FWCI
- 21.72
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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