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The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Effect of Diet Composition and Weight Loss on Resting Energy Expenditure in the POUNDS LOST Study

de Jonge, Lilian, Bray, George A., Smith, Steven R., Ryan, Donna H., de Souza, Russell J., Loria, Catherine M., Champagne, Catherine M., Williamson, Donald A., Sacks, Frank M.·2012·Obesity
DOI 10.1038/oby.2012.127PMC PMC3760199
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Abstract

Weight loss reduces energy expenditure, but it is unclear whether dietary macronutrient composition affects this reduction. We hypothesized that energy expenditure might be modulated by macronutrient composition of the diet. The Prevention of Obesity Using Novel Dietary Strategies (POUNDS) LOST study, a prospective, randomized controlled trial in 811 overweight/obese people who were randomized in a 2 × 2 design to diets containing 20en% or 40en% fat and 15en% or 25en% protein (diets with 65%, 55%, 45%, and 35% carbohydrate) provided the data to test this hypothesis. Resting energy expenditure (REE) was measured at baseline, 6, and 24 months using a ventilated hood. REE declined at 6 months by 99.5 ± 8.0 kcal/day in men and 55.2 ± 10.6 kcal/day in women during the first 6 months. This decline was related to the weight loss, and there was no difference between the diets. REE had returned to baseline by 24 months, but body weight was still 60% below baseline. Measured REE at 6 months was significantly lower than the predicted (−18.2 ± 6.7 kcal/day) and was the result of significant reductions from baseline in the low‐fat diets (65% or 55% carbohydrate), but not in the high fat diet groups. By 24 months the difference had reversed with measured REE being slightly but significantly higher than predicted (21.8 ± 10.1 kcal/day). In conclusion, we found that REE fell significantly after weight loss but was not related to diet composition. Adaptive thermogenesis was evident at 6 months, but not at 24 months.

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Crossref · 10.1038/oby.2012.127

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  • Adaptive thermogenesis was independent of macronutrient composition of the diet.

    “AT was independent of macronutrient composition of the diet [44–47].”

    From Changes in energy expenditure with weight gain and weight loss in humans (2016) · cites this paper as [45]

    The Abstract reports that the overall decline in resting energy expenditure was not related to diet composition. But the Results (Predicted Changes in REE) identify adaptive thermogenesis at six months in the two low-fat diet groups, while the Discussion says it was not significant in the two high-fat groups. Thus the paper does not establish the unqualified claim that adaptive thermogenesis was independent of macronutrient composition. (LLM, conf=0.85)

    Experimental — accuracy not yet measured

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Citations

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Research works printed but not linked: 28

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Metadata

Authors
de Jonge, L., Bray, G. A., Smith, S. R., Ryan, D. H., de Souza, R. J., Loria, C. M., Champagne, C. M., Williamson, D. A., & Sacks, F. M.
Venue
Obesity
Publisher
Wiley
Published
2012-12
Volume
20
Issue
12
Pages
2384-2389
ISSN
  • 1930-7381
  • 1930-739X
DOI
10.1038/oby.2012.127
PMC
PMC3760199
Cited by
51
References
12
Language
en
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 30 d)

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