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Generation of human excitatory forebrain neurons by cooperative binding of proneural NGN2 and homeobox factor EMX1

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Synthetic essentiality between PTEN and core dependency factor PAX7 dictates rhabdomyosarcoma identity

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Neuronal Replenishment via Hydrogel-Rationed Delivery of Reprogramming Factors

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Canalizing cell fate by transcriptional repression

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Chromatin-dependent motif syntax defines differentiation trajectories

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Active repression of cell fate plasticity by PROX1 safeguards hepatocyte identity and prevents liver tumorigenesis

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Transgene-free direct conversion of murine fibroblasts into functional muscle stem cells

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Muscle cell type diversification facilitated by extensive gene duplicationsPreprint

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APOBEC2 safeguards skeletal muscle cell fate through binding chromatin and regulating transcription of non-muscle genes during myoblast differentiation

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Direct In Vitro Reprogramming of Astrocytes into Induced Neurons

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ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors

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MicroRNA-27a-3p targeting Vangl1 and Vangl2 inhibits cell proliferation in mouse granulosa cells

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Developmental Heterogeneity of RhabdomyosarcomaPreprint

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Cell fate acquisition and reprogramming by the proneural transcription factor ASCL1

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Next-generation direct reprogramming

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Recruitment of homodimeric proneural factors by conserved CAT–CAT E-boxes drives major epigenetic reconfiguration in cortical neurogenesis

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Measuring transcription factor binding and gene expression using barcoded self-reporting transposon calling cards and transcriptomes

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Insights and applications of direct neuronal reprogramming

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Effect of Exercise on Regulating miRNA Expression in Brain Health and Diseases

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Cellular identity through the lens of direct lineage reprogramming

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Past, Present, and Future of Direct Cell Reprogramming

Ahlenius, H. (2022) · Cellular Reprogramming · doi:10.1089/cell.2022.0110 · Cited by 4 · see citing works

APOBEC2 is a Transcriptional Repressor required for proper Myoblast DifferentiationPreprint

Lorenzo, J. P., Molla, L., Ibarra, I. L., Ruf, S., Ridani, J., Subramani, P. G., Boulais, J., Harjanto, D., Vonica, A., Noia, J. M. D., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.07.29.223594 · Cited by 4 · see citing works

The regulatory role of pioneer factors during cardiovascular lineage specification – A mini review

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PROX1: A Key Regulator of Hepatocyte Identity and Tumorigenesis

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The comprehensive roadmaps of reprogramming and transformation unveiled antagonistic roles for bHLH transcription factors in the control of cellular plasticityPreprint

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Novel Mechanisms Regulating Myogenic Differentiation in Skeletal Muscle

Honda, T. (2021) · Yamaguchi Medical Journal · doi:10.2342/ymj.70.149

Reprogramming Stars #18: Engineering Cell Fates and Preventing Disease by Repressing Unwanted Plasticity—An Interview with Dr. Moritz Mall

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Distinct DNA-binding syntax and chromatin remodeling capacities of bHLH transcription factors in cell differentiation, reprogramming and cancerPreprint

de Martin, X., Martínez-Miralles, J., Beletskaya, S., Navarro, A., Izquierdo, J., Oliva, B., & Santpere, G. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.02.10.705010

Combinatorial transcription factor interactions drive modular gene regulatory networksPreprint

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Combinatorial and Inducible CRISPRa/i Enables Canalized hiPSC Forward Programming and Iterative Refinement via Single-Cell GenomicsPreprint

Sozza, F., Romano, A., D'Elia, N., Terenzi, M., Ratto, M. L., Cliff, E. R., Nattenberg, G., Bianchi, S. D., Becca, S., Klug, H., et al. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.6885667

Combinatorial transcription factor interactions drive modular gene regulatory networksPreprint

Duan, J., Li, B., Kulkarni, K., Orquera-Tornakian, G., Barth, D., Wang, L. H., Pandit, V., Liou, J., Munshi, N. V., & Hon, G. C. (2026) · eLife · doi:10.7554/elife.111977.1

Combinatorial transcription factor interactions drive modular gene regulatory networksPreprint

Duan, J., Li, B., Kulkarni, K., Orquera-Tornakian, G., Barth, D., Wang, L. H., Pandit, V., Liou, J., Munshi, N. V., & Hon, G. C. (2026) · eLife · doi:10.7554/elife.111977

Proneural factors Ascl1 and Neurog2 contribute to neuronal subtype identities by establishing distinct chromatin landscapes

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Distinct proliferative and neuronal programmes of chromatin binding and gene activation by ASCL1 are cell cycle stage-specific

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Intrinsic DNA binding properties demonstrated for lineage-specifying basic helix-loop-helix transcription factorsPreprint

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Context-dependent activity of a pioneer transcription factor, ASCL1, in early development

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Pioneer factor ASCL1 cooperates with the mSWI/SNF complex at distal regulatory elements to regulate human neural differentiationPreprint

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