In vivo NIR-II fluorescence imaging for biology and medicine

A clearer vision for in vivo imaging

Weissleder, R. (2001) · Nature Biotechnology · doi:10.1038/86684 · Cited by 3,839

Near-infrared fluorophores for biomedical imaging

Hong, G., Antaris, A. L., & Dai, H. (2017) · Nature Biomedical Engineering · doi:10.1038/s41551-016-0010 · Cited by 3,048

Second window for in vivo imaging

Smith, A. M., Mancini, M. C., & Nie, S. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.326 · Cited by 2,848

Noncovalent sidewall functionalization of single-walled carbon nanotubes for protein immobilization

Chen, R. J., Zhang, Y., Wang, D., & Dai, H. (2001) · Journal of the American Chemical Society · doi:10.1021/ja010172b · Cited by 2,534

Optical Sectioning Deep Inside Live Embryos by Selective Plane Illumination Microscopy

Huisken, J., Swoger, J., Bene, F. D., Wittbrodt, J., & Stelzer, E. H. K. (2004) · Science · doi:10.1126/science.1100035 · Cited by 2,370

Nonlinear structured-illumination microscopy: Wide-field fluorescence imaging with theoretically unlimited resolution

Gustafsson, M. G. L. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406877102 · Cited by 2,270

A small-molecule dye for NIR-II imaging

Antaris, A. L., Chen, H., Cheng, K., Sun, Y., Hong, G., Qu, C., Diao, S., Deng, Z., Hu, X., Zhang, B., et al. (2016) · Nature Materials · doi:10.1038/nmat4476 · Cited by 1,778

Carbon nanotubes in biology and medicine: In vitro and in vivo detection, imaging and drug delivery

Liu, Z., Tabakman, S. M., Welsher, K., & Dai, H. (2009) · Nano Research · doi:10.1007/s12274-009-9009-8 · Cited by 1,729

In vivo three-photon microscopy of subcortical structures within an intact mouse brain

Horton, N. G., Wang, K., Kobat, D., Clark, C. G., Wise, F. W., Schaffer, C. B., & Xu, C. (2013) · Nature Photonics · doi:10.1038/nphoton.2012.336 · Cited by 1,505

A route to brightly fluorescent carbon nanotubes for near-infrared imaging in mice

Welsher, K., Liu, Z., Sherlock, S. P., Robinson, J. T., Chen, Z., Daranciang, D., & Dai, H. (2009) · Nature Nanotechnology · doi:10.1038/nnano.2009.294 · Cited by 1,287

Nitric oxide-activatable NIR-II organic small molecule for fluorescence imaging-guided synergistic photodynamic and photothermal therapy

Zhang, X., Li, L., Ren, Y., Li, M., Ma, X., Long, Y., Wang, J., & Tang, Y. (2025) · Chemical Science · doi:10.1039/d5sc03636d · Cited by 16

Brightening New Horizons: Luminescent Transition Metal Complexes in Optical Imaging and Theranostic Applications

Lee, L. C., & Lo, K. K. (2025) · ACS Central Science · doi:10.1021/acscentsci.5c00975 · Cited by 16

A “3+2” Cooperation Pattern of Amphipathic AIE Phototheranostic System for Multimodal Image‐Guided Synergistic Type I/II Photodynamic‐Photothermal Therapy

Ma, H., An, Y., Han, Y., Zhao, F., Zuo, Y., He, G., Lu, Z., Kwok, R. T. K., Sun, J., Lam, J. W. Y., et al. (2025) · Advanced Science · doi:10.1002/advs.202507956 · Cited by 16

Ultrabright NIR‐II Nanoparticles for High‐Resolution In Vivo Imaging: From Systemic Vasculature Visualization to Pathological Microenvironment Monitoring

Lin, D., Huang, W., Yang, H., Zhu, J., Liu, Y., Wang, L., Yan, D., Wang, D., & Tang, B. Z. (2025) · Advanced Materials · doi:10.1002/adma.202510493 · Cited by 16

Supramolecular dyes: advancing precision medicine through molecular engineering

Li, J., Xu, Y., Pang, Y., Zhao, F., Zhang, W., Li, C., Jin, H., Yuan, C., Wang, S., & Sun, Y. (2025) · Chemical Society Reviews · doi:10.1039/d5cs00734h · Cited by 16

A multifunctional “three-in-one” fluorescent theranostic system for hepatic ischemia–reperfusion injury

Liu, J., Yin, D., Zhang, W., Wang, X., James, T. D., Li, P., & Tang, B. (2024) · Chemical Science · doi:10.1039/d4sc04962d · Cited by 16

Macrophage membrane enveloped on double-locked nanoplatform with right-side-out orientation to improving precise theranostic for atherosclerosis

Liu, J., He, Z., Qin, X., Zhang, K., Qu, K., Zhong, Y., Yang, W., & Wu, W. (2025) · Journal of Controlled Release · doi:10.1016/j.jconrel.2025.02.034 · Cited by 16

Multifunctional nanophotonic photoacoustic biosensors: a new era in molecular imaging–guided deep-tissue cancer monitoring

Taha, B. A., Sulaiman, G. M., Addie, A. J., Khalil, K., Ahmed, E. M., Chaudhary, V., & Arsad, N. (2025) · Methods · doi:10.1016/j.ymeth.2025.06.005 · Cited by 16

Nonemissive Ruthenium Complexes for Near Infrared-II Photodynamic, Photothermal, Sonodynamic, and Sonothermal Therapy Against Drug-Resistant Cancer

Song, R., Zhao, R.-Y., Yan, R., Li, X., Zeng, L.-Z., Cai, Z., Chen, J., Ren, X., Cheng, X., & Gao, F. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c01371 · Cited by 15

Electronic-Symmetry-Tuned Emission Beyond 1500 nm in Erbium(III)-Phthalocyanine Complexes for High-Resolution In Vivo Biosensing

Wu, B., Zhang, L., Yan, K., Mei, M., Wu, W., He, Z., Wang, S., & Zhang, F. (2025) · Journal of the American Chemical Society · doi:10.1021/jacs.5c13688 · Cited by 15

A Near-Infrared Fluorescent Probe for Visualization of Acetylcholinesterase Flux in the Acute Epileptic Mice Brain

Fan, L., Wang, R., Zan, Q., Zhao, K., Zhang, Y., Huang, Y., Yu, X. L., Yang, Y., Lu, W., Shuang, S., et al. (2024) · Chemical & Biomedical Imaging · doi:10.1021/cbmi.4c00058 · Cited by 15

NIR-II imaging guided on-site size variable clustered nanosystem to potentiate sonodynamic therapy in deep-seated tumors

Yu, Q., Zhou, Y., Zhang, Q., Li, J., Yan, S., Xu, J., Li, C., Zhou, X., & Sun, Y. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123381 · Cited by 15

Ultrasensitive and Selective Detection of Dopamine Through Substituent-Regulated Evolution of Quantum Defects

Yin, T., Zhao, Y., Zhang, J., Xiao, X., Huang, Y., Ke, B., & Huang, Z. (2025) · ACS Sensors · doi:10.1021/acssensors.5c01153 · Cited by 14

Advanced second near-infrared fluorophores for bioapplications

Bai, Q., Yang, Q., Liu, Y., Li, A., Yin, X.-B., & Wu, S. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.217146 · Cited by 14

Radioisotope-mimetic molecular afterglow probe for downregulated cancer biomarker imaging

Zhang, G., Feng, G., Xu, C., Gao, Z., Zhang, J., Li, L., Zhang, Y., Pu, K., & Ding, D. (2026) · Nature Materials · doi:10.1038/s41563-026-02507-8 · Cited by 14

Stabilizing Radicals in Aggregation-Induced Emission Rotor-Polyoxometalate Crystals for Efficient Photothermal Conversion

He, G., Ou, X., Liu, C., He, S., Han, P., Deng, Z., Wong, L. N., Yuan, G., Xiao, X., Ma, H., et al. (2026) · Journal of the American Chemical Society · doi:10.1021/jacs.6c00335 · Cited by 14

Unravelling the Labyrinth of Organic Semiconducting Chromophores for Fluorescence Bioimaging beyond 1500 nm

Hu, X., Zhu, C., Qin, A., Chen, Z., Yáng, Z., & Huang, W. (2024) · Chemistry of Materials · doi:10.1021/acs.chemmater.4c02379 · Cited by 15

Advances in prostate-specific membrane antigen-targeted theranostics: from radionuclides to near-infrared fluorescence technology

Jiang, Z., Kadeerhan, G., Zhang, J., Guo, W., Guo, H., & Wang, D. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1533532 · Cited by 14

PhotoChem Interplays: Lighting the Way for Drug Delivery and Diagnosis

Banstola, A., Lin, Z., Li, Y., & Wu, M. X. (2025) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2025.115549 · Cited by 14

Selective Lower‐Occupied Through‐Bond Interactions for Efficient Organic Phosphorescence Enabling High‐Resolution Long‐Wavelength Afterglow

Mulimani, R. K., Ueda, S., Miyashita, R., Tsuru, R., Hayashi, K., Shimura, R., Sk, B., Matsuda, S., & Hirata, S. (2025) · Advanced Materials · doi:10.1002/adma.202502611 · Cited by 16

A single fluorescent probe for dual-color imaging and polarity precise analysis in lipid droplets and endoplasmic reticulum

Hu, L., Chen, D., Yang, J. H., Wang, Y., Yu, K., Wang, C., & Wang, H. (2025) · Analytica Chimica Acta · doi:10.1016/j.aca.2025.343703 · Cited by 13

Visible Light Excited Yb3+‐Doped Phosphor Via Eu2+ Bridged Energy Transfer Toward NIR‐II Spectroscopy Application

Li, Z., Zhu, G., Li, H., Zhu, Q., Yan, C., Bai, X., Li, J., & Dong, B. (2025) · Laser & Photonics Review · doi:10.1002/lpor.202402162 · Cited by 13

Three-Dimensional Afterglow Luminescence–MRI Fusion Tomography with Magnetically Targeted Luminescent-Magnetic Nanoparticles for Deep-Seated Tumor Imaging

Zhang, Y., Wen, J., Fan, X., Yu, Y., Zhang, C., Sun, Y., Yin, B., Zhang, Q., Shen, H., Wei, H., et al. (2025) · ACS Nano · doi:10.1021/acsnano.5c10585 · Cited by 13

A Near-Infrared-II Molecular Probe for Early Diagnosis of Acute Kidney Injury Induced by Diverse Etiologies

Zhu, Y., Yan, D., Zhu, J., Xü, H., Zhang, W., Hou, J., Wang, D., & Tang, B. Z. (2025) · ACS Nano · doi:10.1021/acsnano.5c09246 · Cited by 13

Engineering Near-Infrared-II Nanoprobes Reveal Dexmedetomidine Potentiating Brain Waste Clearance in Healthy and Sleep-Restricted Mice

Sun, X., Fang, D., Zhang, X., Zhu, H.-J., Sun, Y., Liu, G., Sun, B., Lü, J., & Zhu, S. (2025) · ACS Nano · doi:10.1021/acsnano.5c10519 · Cited by 13

Visualization of drug release in a chemo-immunotherapy nanoplatform via ratiometric 19 F magnetic resonance imaging

Liu, F., Li, X., Li, Y., Xu, S., Guo, C., & Wang, L. (2024) · Chemical Science · doi:10.1039/d4sc03643c · Cited by 13

Simple design of fluorescein-based probe for rapid and in situ visual monitoring of histamine levels in food spoilage

Geng, J., Huang, Z., Shen, Q., Xu, C., Zhang, L., Wei, C., Fu, C., An, W., & Yu, C. (2024) · Talanta · doi:10.1016/j.talanta.2024.126941 · Cited by 13

Nonfluorescent Near-Infrared Surface-Enhanced Resonance Raman Nanoprobes with Ultrahigh Brightness and Synergistic Photothermal Effect

Qi, C., Shen, L., Li, J., Sun, X., Song, L., Chen, J., Wu, Y., Choo, J., & Chen, L. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c15017 · Cited by 13

Janus Gold Nanodiscs with an Asymmetrically Positioned Polyaniline Nano-Urchin for Photothermal Therapy and Multimodal Imaging in the Second Near-Infrared Window

Lee, E. S., Lee, J., Kim, J., Kim, J., Wi, J., Park, J. Y., Lee, T. G., Choi, B. G., Lee, K. G., Kim, Y., et al. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c22576 · Cited by 13

Advances in small organic molecule fluorescent probes for formaldehyde detection and imaging in pathophysiological processes: A comprehensive review

Jia, T.-T., Kang, G., Jiang, L., Li, Z., Zhao, R., Qin, J., Niu, H., & Ma, L. (2025) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2025.118338 · Cited by 12

Molecularly Engineered Dual-Lock Activatable NIR-II Fluorogenic Probe for Precision Tumor Resection and Real-Time Chemotherapy Response Monitoring

Lu, J., Song, X., Wang, X., Xu, C., Wang, Y., Xing, Y., Yu, F., & Dou, K. (2025) · Analytical Chemistry · doi:10.1021/acs.analchem.5c06362 · Cited by 12

Real-time near-infrared II fluorescence navigation of magnetic nanorobots for image-guided therapy

Dai, Z., Wu, Z., Li, W. J., Xu, S., Xu, D., Xiong, P., Liu, Z., Zhang, C., Qu, L., Liu, L. Q., et al. (2026) · Science Advances · doi:10.1126/sciadv.aea5126 · Cited by 12

Second near-infrared fluorophores: Rational design, optical enhancement strategies, and recent advances in imaging-guided biomedical applications

Yu, H., Ai, L., & Lu, S. (2026) · Chem · doi:10.1016/j.chempr.2025.102867 · Cited by 13

Two-dimensional NIR-II AIE nanotheranostic probes with ultralarge Stokes shifts for surgical navigation and ablation of glioma

Liu, Y., Su, X., Zhong, Y., Shangguan, P., Zhu, J., Luo, Z., Wu, H., Wang, D., Han, T., Wang, J., et al. (2026) · Science Advances · doi:10.1126/sciadv.aeb5389 · Cited by 13

Advances in Lanthanide‐Based NIR‐IIb Probes for In Vivo Biomedical Imaging

Wu, J., Chen, Z., Xie, Y., & Fan, Y. (2024) · Small Methods · doi:10.1002/smtd.202401462 · Cited by 12

Controllable Self‐Assembly of V═O Metalloradical Complex with Intramolecular Charge Transfer for Enhanced NIR‐II Fluorescence Imaging‐Guided Photothermal Therapy

Bao, J., Li, Z., Wang, D., Wang, J., Huang, G., Qian, J., Yang, X., Duan, P., Zhang, S., Bai, F., et al. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202404262 · Cited by 12

Recent advances in low‐background luminescent nanomaterials‐enhanced lateral flow assays for clinical diagnosis

Hao, L., Chen, J., Li, Q., Zhang, D., Huang, Q., Zhang, H., & Li, S. (2025) · Interdisciplinary medicine · doi:10.1002/inmd.20240078 · Cited by 14

Naphthalimide Nanoprobe with Enhanced Electron-Withdrawing Ability and Large Stokes Shift for NIR-II Fluorescence Imaging-Guided Phototheranostics

Peng, M., Wei, H., Wang, Q., Jun, G., & Yin, M. (2025) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c19915 · Cited by 12

Smart fluorogenic tools: From designing principles to visualization of multistep protein aggregation

Wan, J., Huang, C., Chen, Z., Wan, J., Ding, W., Liu, D., Feng, L., Yue, M., Li, M., Ju, M., et al. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.216625 · Cited by 12

Conjugated Oligomer‐Based NIR‐II Chemiluminescence Nanosensor for In Vivo Imaging

Li, L., Zhang, X., Ren, Y., Bao, B., Li, M., Zhang, M., Wang, J., Wang, J., & Tang, Y. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202424286 · Cited by 13

Novel lanthanide( iii )/gallium( iii ) metallacrowns with appended visible-absorbing organic sensitizers for molecular near-infrared imaging of living cells

Lathion, T., Bourseguin, J., Eliseeva, S. V., Zeller, M., Pètoud, S., & Pecoraro, V. L. (2025) · Chemical Science · doi:10.1039/d5sc01320h · Cited by 12

Thienothiadiazole-based NIR-II D-A-D dye for fluorescence and photoacoustic imaging-navigated photothermal therapy

Sun, X., Luo, M., Xie, X., Liu, M., Wang, W., Zhang, T., An, L., Shao, J., Dong, X., & Cai, Y. (2025) · Chinese Chemical Letters · doi:10.1016/j.cclet.2025.111509 · Cited by 12

Recent advances in the construction, imaging and phototherapy applications of NIR-II J-aggregates based on different fluorophores

Sun, G., Zhang, Y., Zhou, N., Huo, F., & Yin, C. (2025) · Dyes and Pigments · doi:10.1016/j.dyepig.2025.113054 · Cited by 11

Infrared Single‐Pixel Hyperspectral Imaging Via Spatial‐Temporal Multiplexing

Sun, B., Huang, K., Zhao, Z.-B., Dong, B., Fang, J., & Zeng, H. (2025) · Laser & Photonics Review · doi:10.1002/lpor.202501321 · Cited by 11

NIR-II luminescent rare-earth-doped nanomaterials for precision targeted and surgical navigation of tumors

Lin, B., Lv, R., Ju, Z., & Ansari, A. A. (2025) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2025.217251 · Cited by 11

Mechanochemical Acceptor Engineering for NIR-I and NIR-II Fluorophores Enabling Orthogonal Ureter-Vascular Image-Guided Surgery

Xie, H., Tian, Z., Zhang, R., Huang, Z., Wang, Y., Liu, Z., Kwok, R. T. K., Lam, J. W. Y., Zhao, Z., Huang, Y., et al. (2025) · Journal of the American Chemical Society · doi:10.1021/jacs.5c17089 · Cited by 11

Tandem Auxochrome Design Enables Ready Access to Deep Shortwave Infrared Dyes

Yan, K., Zeng, Z., Liu, H., Zhang, L., Dong, Y., Chen, Z., Wang, S., & Zhang, F. (2026) · Journal of the American Chemical Society · doi:10.1021/jacs.6c02935 · Cited by 11

Visible to near-infrared light activated photoacids: Molecular architecture for chemical and biological applications

Jiang, J., Xu, Z., Li, T., & Lv, Z. (2025) · Journal of Organometallic Chemistry · doi:10.1016/j.jorganchem.2025.123525 · Cited by 11

Structural rigidity control toward Cr3 +-based broadband near-infrared luminescence with enhanced thermal stability and luminescent intensity

Zhong, Y., Cao, Q., Xie, J., Su, T., Li, Y., Wang, W., Wang, S., Pan, Y., Wei, X., & Li, Y. (2025) · Journal of Alloys and Compounds · doi:10.1016/j.jallcom.2025.179551 · Cited by 11

Dynamic Pathophysiological Insight into the Brain by NIR‐II Imaging

Chen, S., Chen, H., Li, X., He, S., Shou, K., Qian, K., Fang, Z., Gu, F., Chang, B., & Cheng, Z. (2025) · Advanced Science · doi:10.1002/advs.202416390 · Cited by 11

Organic Molecules as a Bridge Connecting Photoelectrochemistry and Fluorescence for Dual-Signal Assay

Chang, J., Zhang, Z., Qu, C., Han, Q., & Xu, L. (2025) · Analytical Chemistry · doi:10.1021/acs.analchem.4c06431 · Cited by 11

Aza-BODIPY dye with D-π-A architecture for 1064 nm laser-triggered photothermal theranostics

An, D., Jiang, W., Zhang, Z., Wang, S. S., Wang, W., Miao, C., Shao, J., & Dong, X. (2025) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2025.138144 · Cited by 11

Universal NIR‐II‐Emitting Unimolecular Micelles with Tailorable Pharmacokinetic and Optical Properties for Adaptive Imaging

Hou, S., Fan, G., Gu, Y., Dong, Z., Wang, M., Jia, H., Li, H., Han, L., Qian, H., He, F., et al. (2025) · Advanced Materials · doi:10.1002/adma.202509266 · Cited by 11

An optical meta-image-processor for enhanced imaging through strongly scattering media

Liang, H., Ye, W., Gao, M., Chen, L., Liu, Y., Wang, J., Li, J., Yuan, J., & Wang, X. (2025) · Nature Communications · doi:10.1038/s41467-025-64746-8 · Cited by 11

NIR‐II Fluorescent Protein Created by In Situ Albumin‐Tagging for Sensitive and Specific Imaging of Blood‐Brain Barrier Disruption

Xu, J., Du, Y., Zhu, N., Li, J., Zhang, Y., Zhou, D., & Zhu, S. (2025) · Advanced Science · doi:10.1002/advs.202500443 · Cited by 10

High-selectivity NIR biosensor and in vivo imaging for Hg2+ detection based on a DNA-wrapped single-chirality carbon nanotube

Wang, L., Liu, H., Li, L., Guo, R., Yang, X., Chen, X., Wen, Y., Cao, M., Yan, J., & Liu, G. (2025) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2025.138979 · Cited by 10

Polarization‐Dependent 3D Holography Generated by Inverse Design Nanoprinting Metasurface

Xiong, L., Gong, J., Zhang, F., Miao, W., He, Q., Zhang, D., Cai, Y., & Chi, N. (2025) · Advanced Science · doi:10.1002/advs.202519147 · Cited by 10

Recent developments in near-infrared phosphors for broad-band light-emitting diodes light sources

Hu, Y., Qiao, J., Li, D., Gao, C., & Xia, Z. (2026) · Journal of Rare Earths · doi:10.1016/j.jre.2026.02.014 · Cited by 10

Rational Design of Organic NIR-II fluorophores for advanced Photothermal and photodynamic therapy

Zou, M., Jiao, J., Lv, M., Hou, L., Zhou, S., Chen, Z., & Mo, T. (2026) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2026.217643 · Cited by 10

The role of temperature in the photoluminescence quantum yield (PLQY) of Ag 2 S-based nanocrystals

Wang, P., Morales-Márquez, R., Cervás, G., Medel, A. H., Ogáyar, M. P., de Aberasturi, D. J., de Isidro, A., Torres‐Pardo, A., Palomares, F. J., Garcia‐Orrit, S., et al. (2024) · Materials Horizons · doi:10.1039/d4mh01016g · Cited by 10

Conjugated Polymer for NIR-II Phototheranostics toward Tumor

Pan, J. W., Li, W., Wang, M., Peng, C., Dong, J., Zhou, Q., & Xia, F. (2024) · Chemistry of Materials · doi:10.1021/acs.chemmater.4c02176 · Cited by 10

Tm3+-Based Downshifting Nanoprobes with Enhanced Luminescence at 1680 nm for In Vivo Vascular Growth Monitoring

Xu, R., Cao, H., Yang, Y., Han, F., Lin, D., Chen, X., Wu, C., Liu, L., Yu, B., & Qu, J. (2024) · ACS Nano · doi:10.1021/acsnano.4c14468 · Cited by 10

A Spiro‐Based NIR‐II Photosensitizer with Efficient ROS Generation and Thermal Conversion Performances for Imaging‐Guided Tumor Theranostics

Jin, Y., Xu, K., Ren, B., Shao, J., Ou, C., & Xie, L. (2025) · Advanced Healthcare Materials · doi:10.1002/adhm.202404783 · Cited by 10

A novel acridine-based mitochondria-targeted near-infrared fluorescent probe for the detection of HOCl/ONOO− in vivo

Zhu, Y., Liu, C., Rong, X., Zhu, Y., Wen, H., Zheng, M., Sheng, W., Huang, S., & Zhu, B. (2025) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2025.138143 · Cited by 10

A Water-Soluble Probe for Visualizing Immune Activation for Microbial Resistance in Rice Crops via NIR-II Fluorescent Imaging

Li, R., Zeng, F., & Wu, S. (2025) · Analytical Chemistry · doi:10.1021/acs.analchem.5c02428 · Cited by 10

A dual-excitation ratiometric NIR-II fluorescent nanoplatform enables high contrast in vivo imaging

Liu, Y., Teng, L., Zhang, B., Zhang, X., & Song, G. (2025) · Chemical Science · doi:10.1039/d5sc02705e · Cited by 10

Manipulating extracellular matrix to enhance intratumor drug delivery for nanomaterial-based photothermal therapy

Zhang, M., Chen, Y., Li, Y., Zhao, Y., Lv, B., Cao, J., Yu, B., & Cong, H. (2025) · Chinese Chemical Letters · doi:10.1016/j.cclet.2025.111588 · Cited by 10

Near-infrared II excited off-on fluorescent probe for molecular imaging of copper ions in Wilson disease

Deng, R., Gao, Y., Zhao, S., Li, Y., He, S., Gao, Y., Zhai, Z., Zheng, J., Nie, J., & Chang, Y. (2025) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2025.138408 · Cited by 10

Mid-infrared superconducting nanowire single-photon detectors: Potential, progress, and challenges

Taylor, G. G., & Hadfield, R. H. (2026) · Applied Physics Letters · doi:10.1063/5.0303649 · Cited by 13

In vivo NIR-II fluorescence imaging based on microscopy set-ups: probes, set-ups, bioimaging and bioanalysis applications

Yang, Y., Zhang, H., Yáng, Z., & Huang, W. (2026) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2026.217598 · Cited by 11

Atomically Precise Metal Clusters for NIR-II Imaging

Ma, H., Ma, D., Liu, P. X., Wang, H., & Zhang, X. (2026) · Accounts of Chemical Research · doi:10.1021/acs.accounts.5c00837 · Cited by 10

Organic probes for three‐photon fluorescence imaging in NIR‐II window: Design, applications, and perspectives

Yang, Y., Cen, C., Kan, L., Zhao, Q., Huang, Z., & Li, S. (2024) · Interdisciplinary materials · doi:10.1002/idm2.12217 · Cited by 9

Advances in Tracing Techniques: Mapping the Trajectory of Mesenchymal Stem-Cell-Derived Extracellular Vesicles

Li, J., Wang, Z., Wei, Y., Li, W., He, M., Kang, J., Xu, J., & Liu, D. (2025) · Chemical & Biomedical Imaging · doi:10.1021/cbmi.4c00085 · Cited by 11

Self-Assembly versus Coassembly: An Amphiphilic NIR-II Aggregation-Induced Emission Luminogen for Phototheranostics of Orthotopic Glioblastoma

Sun, Y., Yan, X., Wang, D., Zhu, J. Z., Su, H., Zhu, D., Yan, D., & Tang, B. Z. (2025) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c00590 · Cited by 9

Activatable and Renal Metabolizable NIR-II Emissive Au Nanoprobe for Real-Time Monitoring of Kidney GSH

Wen, X., Xu, Y., Chen, Z., Tian, J., Zhong, H., Wu, R., & Zeng, S. (2025) · Nano Letters · doi:10.1021/acs.nanolett.5c02358 · Cited by 9

Atomically Precise Au32 Clusters for 3D Visualization of Pathological Progression in Sepsis-Induced Multi-Organ Injury

Li, S., Jia, K., Ao, S., Ma, H., Zang, J., Yan, H., Qi, X., Yan, Y., Ma, D., Huo, Y., et al. (2025) · Nano Letters · doi:10.1021/acs.nanolett.5c02725 · Cited by 9

Brain-Derived Exosomes in Neurodevelopmental and Neuropsychiatric Disorders: Molecular Insights, Therapeutic Potential, and Translational Challenges

Nikanfar, M., Avci, Ç. B., Khalilnezhad, A., Shahriyari, E., & Nourazarian, A. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05247-z · Cited by 10

Clinical Integration of NIR-II Fluorescence Imaging for Cancer Surgery: A Translational Evaluation of Preclinical and Intraoperative Systems

Isuri, R. K., Williams, J. N., Rioux, D., Dorval, P., Chung, W., Dancer, P.-A., & Delikatny, E. J. (2025) · Cancers · doi:10.3390/cancers17162676 · Cited by 9

A water-soluble NIR-II fluorescent probe for non-invasive real-time detection of blood ATP via optoacoustic and fluorescence imaging

Zhang, Y., Zeng, F., & Wu, S. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb01208b · Cited by 9

A sub-volt near-IR lithium tantalate electro-optic modulator

Powell, K. B., Renaud, D. L., Li, X., Assumpção, D., Xin, C. J., Sinclair, N. E., & Lončar, M. (2025) · APL Photonics · doi:10.1063/5.0278724 · Cited by 9

Enriching BODIPY Triplet States via Ruthenium(II) Conjugation for Improved Photodynamic Therapy

Paul, S., & Bera, A. (2026) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c02024 · Cited by 9

STING-Activating nanoplatforms for image-guided sonodynamic cancer therapy

Zhang, L., Huang, D., Li, J., Mo, L., Qin, T., Xing, B., Xiao, B., Xu, C., Xiao, H., Zeng, L., et al. (2026) · Molecular Cancer · doi:10.1186/s12943-026-02591-z · Cited by 9

Stimuli-responsive nanoplatforms for central nervous system disorders: integrating delivery, modulation, and imaging

Chen, Y., Ding, Y., Lin, H., & Shi, J. (2026) · Chemical Society Reviews · doi:10.1039/d5cs01323b · Cited by 9

NIR‐II Fluorescence/Photoacoustic Dual Ratiometric Probes with Unique Recognition Site for Quantitatively Visualizing H 2 S 2 in Vivo

Hu, B., Liu, Q., Jiang, Y., Huang, Y., Ji, H., Zhang, J., Wang, X., Shen, X., & Chen, H. (2024) · Angewandte Chemie · doi:10.1002/ange.202418378 · Cited by 8

The second near-infrared (NIR-II) window excitable/emissive organic/polymeric fluorescent molecules for bioimaging application

Liu, G., Wang, C., & Lu, G. (2024) · Journal of Innovative Optical Health Sciences · doi:10.1142/s1793545825300022 · Cited by 9

Harnessing NIR-II luminescence in ultrasmall gold nanoparticles for enhanced biomedical applications

Zhou, T., & Li, Z. (2024) · Science China Materials · doi:10.1007/s40843-024-3187-8 · Cited by 8

Nonlight-Driven Aggregation-Induced Emission Luminogens for Bioimaging and Theranostics

Tian, Y., Huang, W., Sheng, Z., Yan, D., Wang, D., & Tang, B. Z. (2025) · Chemical & Biomedical Imaging · doi:10.1021/cbmi.4c00108 · Cited by 8

Strategies for Developing Activity‐Based Luminescent Probes for Imaging and Diagnosing Inflammatory Bowel Diseases

Zhou, J., Yuan, B., Ren, T., & Yuan, L. (2025) · Chemistry - A European Journal · doi:10.1002/chem.202500872 · Cited by 8

Nanomaterial-assisted pancreatic cancer theranostics

Liu, Y., Xu, H., Bai, S., Chen, T., Ma, X., Lin, J., Sun, L., Gao, C., Wu, A., & Li, Q. (2025) · Regenerative Biomaterials · doi:10.1093/rb/rbaf054 · Cited by 8

Ratiometric Nanoprobes With Emission Beyond 1600 nm for In Vivo Inflammation Detection

Yang, X., Du, P., Deng, Z., Liang, Y., Zhang, J., Dong, H., Sun, L., & Yan, C. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202512831 · Cited by 8

Dye Sensitized Lanthanide‐Triplet Cascade Energy Transfer for Near‐Infrared Therapy

Li, H. Y., Ruan, J., Jiang, Q., Deng, R., Li, Q., Ye, C., Ren, B., Fu, W., & Zheng, B. (2025) · Advanced Functional Materials · doi:10.1002/adfm.202519395 · Cited by 8

AI‐Driven Acceleration of Fluorescence Probe Discovery

蒋雪峰, Li, Y. W., Tian, X., Yang, S., Luo, R., Zhou, C., Liu, Y., Hu, J., Feng, S., Gan, L., et al. (2025) · Advanced Science · doi:10.1002/advs.202515604 · Cited by 8

An Integrated NIR-II Fluorescence-Free Reporter for Multimodal Imaging-Guided Breast-Conserving Surgery

Wang, X., Shi, K., Wang, Y., Shao, C., & Li, J. (2026) · Nano Letters · doi:10.1021/acs.nanolett.5c04589 · Cited by 8

Sensitivity Enhancement of Multiplex Lateral Flow Immunoassays by NIR-II Fluorescence and Thermal Contrast

Luo, Y.-C., Hsieh, Y.-C., Huang, C., Liu, Y., Huang, H.-T., Chen, Y.-C., Wang, T.-Y., Chen, C., & Chan, Y. (2026) · Analytical Chemistry · doi:10.1021/acs.analchem.5c06734 · Cited by 8

Origin of the Unusual Narrowband Near-Infrared Emission from Cr 3+ -Doped Oxides

Xiao, Y., Xiao, W., Zheng, T., Zhao, H., Du, P., Zhang, R., Lou, C., Tang, M., Chen, M.-X., Yang, W., et al. (2026) · Journal of the American Chemical Society · doi:10.1021/jacs.6c00117 · Cited by 8

Optical probes for bioimaging of tumor-infiltrating immune cells and their applications in cancer immunotherapy

Chen, X., Hu, C., Kim, H., Zhang, L., Zhang, Z., Liu, H., & Yoon, J. (2026) · Chemical Society Reviews · doi:10.1039/d5cs01412c · Cited by 8

Extended π‐Conjugated Bridge Strategy for an Enhanced Stokes Shift and Multimodal Imaging‐Guided Type I/II Photodynamic Therapy Integrated With Photothermal Therapy

Jin, C., Zhao, F., Zhang, Y., Ji, J., Han, Y., Lu, X., Wu, P., Chen, C., Yang, Y., Feng, Y., et al. (2026) · Aggregate · doi:10.1002/agt2.70360 · Cited by 9

Construction and functionalization of thienobenzo-fused indolium heptamethine cyanines for near-infrared bioimaging application

Ma, X., Lin, Z., Fu, Y., Liu, S. H., Yin, J., & Yang, G. (2026) · Science China Chemistry · doi:10.1007/s11426-026-3372-3 · Cited by 8

Size-tuned PEGylated NIR-II fluorescent probes for high-contrast plant imaging and TMV detection

Zhao, F., Xu, Y., Lü, M.-J., Tu, L., Li, C., Dou, Y., Li, J., Li, X.-Y., & Sun, Y. (2025) · Journal of Nanobiotechnology · doi:10.1186/s12951-025-03452-5 · Cited by 8

A Hf(IV)‐Coordinated NIR‐II Fluorescence “Turn‐On” Nanoprobe for Precise Imaging‐Guided Surgery in Breast Cancer

He, Y., Lin, J., Bai, J., Shen, X., Lou, K., Zhu, Y., Qiao, Z., Chen, W., Li, Y., Liu, X., et al. (2025) · Advanced Science · doi:10.1002/advs.202413385 · Cited by 7

Recent advances in NIR-II fluorescence imaging for biomedical applications

Xu, B., Xu, K., Li, S., Sheng, H., Li, H., Zhang, X., Wang, Y., Feng, S., & Chen, J. (2026) · Advanced Interventional Materials · doi:10.1016/j.advim.2026.100016 · Cited by 3

Advances in the near-infrared Ⅱ for in vivo fluorescence imaging applications: A review

Zou, M., Wang, Y., Jiao, J., Lv, M., & Mo, T. (2025) · Talanta · doi:10.1016/j.talanta.2025.128630 · Cited by 15

Recent Advances in Second Near-Infrared Region (NIR-II) Fluorophores and Biomedical Applications

Chen, Y., Xue, L., Zhu, Q., Feng, Y., & Wu, M. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2021.750404 · Cited by 97

NIR-II Fluorophores: From Synthesis to Biological Applications

Duo, Y., Zhao, L., Wang, Z.-G., & Liu, S. (2023) · Journal of Analysis and Testing · doi:10.1007/s41664-023-00254-2 · Cited by 46

Advanced Fluorescence Imaging Technology in the Near-Infrared-II Window for Biomedical Applications

Li, C., Chen, G., Zhang, Y., Wu, F., & Wang, Q. (2020) · Journal of the American Chemical Society · doi:10.1021/jacs.0c07022 · Cited by 1,037