Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond

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Tryptophan metabolic pathway plays a key role in the stress-induced emotional eating

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The role of metabolic reprogramming in immune escape of triple-negative breast cancer

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The aryl hydrocarbon receptor facilitates the human cytomegalovirus-mediated G1/S block to cell cycle progression

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Tryptophan 2, 3‑dioxygenase promotes proliferation, migration and invasion of ovarian cancer cells

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Cooperative Hedgehog/GLI and JAK/STAT signaling drives immunosuppressive tryptophan/kynurenine metabolism via synergistic induction of IDO1 in skin cancer

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Epacadostat Overcomes Cetuximab Resistance in Colorectal Cancer by Targeting IDO ‐Mediated Tryptophan Metabolism

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Kai-Xin-San ameliorates fluoxetine-resistant depressive-like behaviors by modulating tryptophan-kynurenine metabolic homeostasis in a rodent model

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Multi-omics analysis of human plasma reveals reprogramming of tryptophan metabolism associated with inflammation in Mycoplasma pneumoniae pneumonia in children

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Serum tryptophan-kynurenine metabolites served as biomarkers of disease activity in rheumatoid arthritis and linked to immune imbalance

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Production, Mechanisms, and Therapeutic Strategies of Tryptophan Metabolites in CNS Diseases

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Tryptophan 2,3‐dioxygenase 2 plays a key role in regulating the activation of fibroblast‐like synoviocytes in autoimmune arthritis

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Induction of IDO1 and Kynurenine by Serine Proteases Subtilisin, Prostate Specific Antigen, CD26 and HtrA: A New Form of Immunosuppression?

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Functional components of Chinese rice wine can ameliorate diabetic cardiomyopathy through the modulation of autophagy, apoptosis, gut microbiota, and metabolites

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Depletion of gut microbiota resistance in 5×FAD mice enhances the therapeutic effect of mesenchymal stem cell-derived exosomes

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Tryptophan metabolism promotes immune evasion in human pancreatic β cells

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Impaired tryptophan metabolism by type 2 inflammation in epithelium worsening asthma

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Wendan Decoction exerts therapeutic effects on insomnia by regulating gut microbiota and tryptophan metabolism

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4,6-Disubstituted-1H-Indazole-4-Amine derivatives with immune-chemotherapy effect and in vivo antitumor activity

Huo, C., Luo, Z., Ning, X.-L., Kang, X., Qin, Y. F., Guo, Y., Li, G., Wang, Z., Li, Y., & Qian, S. (2022) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2022.114625 · Cited by 14

Biochemical alterations in the follicular fluid of bovine peri-ovulatory follicles and their association with final oocyte maturation

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Integration of microbial metabolomics and microbiomics uncovers a novel mechanism underlying the antidiabetic property of stachyose

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Regulation of metabolism in pancreatic ductal adenocarcinoma via nanotechnology-enabled strategies

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Metagenomic and Untargeted Metabolomic Analysis of the Effect of Sporisorium reilianum Polysaccharide on Improving Obesity

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(2015) · Thammasat University Digital Collections