T cells and the skin: from protective immunity to inflammatory skin disorders

Control of Regulatory T Cell Development by the Transcription Factor Foxp3

Hori, S., Nomura, T., & Sakaguchi, S. (2003) · Science · doi:10.1126/science.1079490 · Cited by 8,187

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Fontenot, J. D., Gavin, M. A., & Rudensky, A. Y. (2003) · Nature Immunology · doi:10.1038/ni904 · Cited by 7,745

Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

Sallusto, F., Lenig, D., Förster, R., Lipp, M., & Lanzavecchia, A. (1999) · Nature · doi:10.1038/44385 · Cited by 5,846

The Role of Tumoral FOXP3 on Cell Proliferation, Migration, and Invasion in Gastric Cancer

Zhang, L., Xu, J., Zhang, X., Zhang, Y., Wang, L., Huang, X., & Xu, Z. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000479442 · Cited by 4,090

Of Mice and Not Men: Differences between Mouse and Human Immunology

Mestas, J., & Hughes, C. C. W. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.5.2731 · Cited by 3,822

IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines

Schmitz, J., Owyang, A. M., Oldham, E. R., Song, Y., Murphy, E., McClanahan, T. K., Zurawski, G., Moshrefi, M., Qin, J., Li, X., et al. (2005) · Immunity · doi:10.1016/j.immuni.2005.09.015 · Cited by 3,773

The skin microbiome

Grice, E. A., & Segre, J. A. (2011) · Nature Reviews Microbiology · doi:10.1038/nrmicro2537 · Cited by 3,143

A Genome-Wide Association Study Identifies IL23R as an Inflammatory Bowel Disease Gene

Duerr, R. H., Taylor, K. D., Brant, S. R., Rioux, J. D., Silverberg, M. S., Daly, M. J., Steinhart, A. H., Abraham, C., Regueiro, M., Griffiths, A., et al. (2006) · Science · doi:10.1126/science.1135245 · Cited by 3,039

Psoriasis

Nestle, F. O., Kaplan, D. H., & Barker, J. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0804595 · Cited by 2,867

An essential role for Scurfin in CD4+CD25+ T regulatory cells

Khattri, R., Cox, T., Yasayko, S.-A., & Ramsdell, F. (2003) · Nature Immunology · doi:10.1038/ni909 · Cited by 2,860

Multicytokine-based transcriptome-wide association study for 7 inflammatory skin disorders identifies candidate causal genes in keratinocytes

Zhang, H., Patrick, M. T., Sarkar, M. K., Wasikowski, R., Li, Q., Uppala, R., White, B. E. P., Petukhova, L., Dand, N., Stuart, P. E., et al. (2026) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2026.05.013 · Cited by 1

Decreased epidermal AXL expression and increased infiltration of AXL‐expressing dendritic cells in psoriasis

Ito, Y., Shibata, S., Koyama, A., Li, L., Sugimoto, E., Taira, H., Mizuno, Y., Awaji, K., & Sato, S. (2023) · Journal of Cutaneous Immunology and Allergy · doi:10.1002/cia2.12319 · Cited by 1

Incorporating NK Cells in a Three-Dimensional Organotypic Culture System for Human Skin Stem Cells: Modeling Skin Diseases and Immune Cell Interplay

Arjmand, B., Hamidpour, S. K., Tayanloo-Beik, A., Arjmand, R., Rezaei–Tavirani, M., Namazi, N., Ojagh, H., & Larijani, B. A. (2023) · Methods in molecular biology · doi:10.1007/7651_2023_504 · Cited by 1

Intradermal administration of novel particulate Chlamydia trachomatis vaccine candidates drives protective immune responses

Huynh, D. T., Nolfi, E., Guleed, S., Medfai, L., Wolf, N., Uijen, R. F., de Jonge, M. I., van Ulsen, P., Dietrich, J., Luirink, J., et al. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117563 · Cited by 1

Decreased Oxidative Stress Markers in Patients with Active and Generalized Vitiligo

Özcan, Y., Karagün, E., & Alpay, M. (2022) · Konuralp Tıp Dergisi · doi:10.18521/ktd.880577 · Cited by 1

CCR7+ CD4 T Cell Immunosurveillance Disrupted in Chronic SIV-Induced Neuroinflammation in Rhesus BrainPreprint

Elizaldi, S. R., Hawes, C. E., Verma, A., Dinasarapu, A. R., Lakshmanappa, Y. S., Schlegel, B. T., Rajasundaram, D., Li, J., Durbin-Johnson, B. P., Ma, Z.-M., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.08.28.555037 · Cited by 1

Comparison of canine and human immune system response to DemodicosisPreprint

Nooraei, S., & Mohseni, Z. (2024) · doi:10.22541/au.171919493.36798843/v1 · Cited by 1

Adjuvants for Non‐Invasive Routes of Vaccine Delivery

Rawal, S. U., Pandya, T., Kulkarni, M., Patel, R., & Menon, A. K. (2025) · doi:10.1002/9781394237654.ch7 · Cited by 1

Innate Immunity in Epidermis

Blumenberg, M. (2020) · Wiley eBooks · doi:10.1002/9781119593058.ch12

Vitiligo

Várvölgyi, T., & Szegedi, A. (2021) · Bőrgyógyászati és Venerológiai Szemle · doi:10.7188/bvsz.2021.97.3.5

Immunologie Update für Dermatologen – woran wird geforscht?

Jahn, S., Diamanti, E., & Herbst, M. (2022) · Aktuelle Dermatologie · doi:10.1055/a-1773-9174

Análise da interação de células dendríticas- linfócitos T e macrófagos na dermatite de contato alérgica por metilisotiazolinona e metilcloroisotiazolinona

Virgens, A. R. (2022) · doi:10.11606/t.5.2022.tde-09062022-122503

Physiopathologie des lymphomes T cutanés épidermotropes (Mycosis fongoïde et syndrome de Sézary)

Amatore, F., Battistella, M., & Ortonne, N. (2022) · Annales de Dermatologie et de Vénéréologie - FMC · doi:10.1016/j.fander.2022.07.007

Canine amnion membrane derived mesenchymal stem cells alleviate atopic dermatitis though TGF-β1 and IDO1Preprint

Kim, M., Gong, D., Han, M., Roh, K.-H., Koo, H., Lee, S., & Kang, K. (2023) · Research Square · doi:10.21203/rs.3.rs-2656900/v1

Lymphocyte Adhesion and Trafficking

Jalkanen, S., & Salmi, M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-7020-8165-1.00016-2

Biology of Cancer

Alsiary, R., Katouah, H. A., Al-Amodi, H. S. A. B., & Al-Toub, M. (2023) · BENTHAM SCIENCE PUBLISHERS eBooks · doi:10.2174/9789815080384123010007

Inflammation, Immunology and Allergy

Haniffa, M. A. (2024) · Wiley eBooks · doi:10.1002/9781119709268.rook009

Delayed hypersensitivity and its relationship with the nutritional status of older adult women

Gálvez-Romero, J. L. (2025) · Revista Alergia México · doi:10.29262/ram.v72i1.1436

Lichen planus onset during interleukin 23 blockade for treatment of psoriasis

Abbas, A., Schroeder, A., Elston, C. A., Raman, C., & Elewski, B. E. (2025) · JAAD Case Reports · doi:10.1016/j.jdcr.2025.06.057

3 Overview of Basic Science

(2025) · Thieme Medical Publishers eBooks · doi:10.1055/b-0045-217910

Additional file 1 of Small-molecule inhibitors, immune checkpoint inhibitors, and more: FDA-approved novel therapeutic drugs for solid tumors from 1991 to 2021

Wu, Q., Qian, W., Sun, X., & Jiang, S. (2022) · Figshare · doi:10.6084/m9.figshare.21301428

Berries and skin health: evaluating their role in dermatological conditions

Tugume, P., Ssenku, E. J., Walusansa, A., & Anywar, G. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-33935-6.00018-7

Targeting ROCK2 for Atopic Dermatitis Relief

Liu, W., & Ju, J. (2026) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6c00504

Skin Deep: Uncovering the Early Events of Crimean–Congo Hemorrhagic Fever Virus at the Tick–Host–Virus Interface

Olal, C., Burch, M., & Bente, D. A. (2026) · Viruses · doi:10.3390/v18040429

Evaluation in vitro de la sensibilisation cutanée aux xénobiotiques : Pertinence d’un modèle de co-culture épiderme reconstruit humain/cellules THP-1

Thélu, A. (2019) · theses.fr (ABES) · doi:10.70675/0958a7daze8d7z4adaz9db4z01df5bdd3bc8

Dynamique des réponses lymphocytaires T locales et systémiques à l'injection d'un vaccin dans la peau

Joly, C. (2019) · theses.fr (ABES) · doi:10.70675/a11cac90z41cbz4fcez9944zaba2b9ada283

Study of the Immune regulation in psoriatic skin and the inflammatory microenvironment in melanoma

German, B. (2020) · theses.fr (ABES) · doi:10.70675/33496ea8z3fc1z496fz9fd5z8d9394591acd

Étude du sulfure d’hydrogène sur les fonctions immunitaires des kératinocytes : implication physiopathologique dans le contexte de la brûlure

Gross-Amat, O. (2020) · theses.fr (ABES) · doi:10.70675/da140857zb42az411az8297ze36394ad4d98

Inducible CO-Stimulator (ICOS) est exprimé dans les lymphomes T cutanés et son ciblage permet l'inhibition des cellules tumorales

Amatore, F. (2021) · theses.fr (ABES) · doi:10.70675/ebda3687z08b3z4b07z858dza96ad1769e80

Caractérisation phénotypique et fonctionnelle des lymphocytes T résidents mémoires infiltrant la peau non-lésionnelle des patients atteints de vitiligo

Migayron, L. (2023) · theses.fr (ABES) · doi:10.70675/1db7db0ez67fez4e4azbe83zb29d31fc1471

Impact des interférons de type I sur le phénotype et la fonction des mélanocytes au cours du vitiligo

Merhi, R. (2024) · theses.fr (ABES) · doi:10.70675/9f7d00cdz3de4z4cd5z9784za5bd3ee702e0

Fibroblast-encoded inflammatory memory orchestrates recurrent skin inflammation via NNMT-dependent metabolic remodelingPreprint

Zhou, Y., Li, K., Xie, Y., Su, C., Li, Z., Yang, Y., Qiao, P., Liu, W., Bai, Y., Xue, K., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.04.27.721223

Traditional to Advanced Wound Care: Classification, Healing Stages, and Technological Progress: A Comprehensive Review

Lakshmi Priya, M., Seethalakshmi, K., Mohandoss, S., Jency, M., & Sarala, P. (2026) · Trends in Biomaterials and Artificial Organs · doi:10.65795/ezjwzz72

Dual anti-inflammatory topical therapy via drug co-encapsulation in solid lipid nanoparticles: enhanced cutaneous delivery and cytokine suppression

Morais, M. F., Silvestrini, A. V. P., Ramos, A. P., & Bentley, M. V. L. B. (2026) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2026.108768

Biomimetic Dermal Substitutes for Skin Reconstruction: Advances in Scaffold Design, Biological Integration, and Clinical Performance

Măciuceanu-Zărnescu, B. M., Lungu, I. I., Niculescu, A.-G., Scafa‐Udriște, A., Baciu, C. C., Anghel, D. N., Rădulescu, A. R., Grumezescu, A. M., & Vâlcea, S. (2026) · Journal of Functional Biomaterials · doi:10.3390/jfb17080397

Skewed MHC Class I Peptide Presentation in Psoriatic Arthritis

Comdühr, S., Sauer, T., Deckert, S., Pitann, S., Schäfer, M., Gemoll, T., Arnold, S., Klapa, S., Riemekasten, G., Thaçi, D., et al. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27167317

MODERN CONCEPTS OF THE ROLE OF CYTOKINES IN THE DYSREGULATION OF THE IMMUNE SYSTEM IN PSORIASIS

Літус, І. О. (2026) · The Medical and Ecological Problems · doi:10.31718/mep.2026.30.2.07

TRPV4 mediates low-humidity responses in epidermal keratinocytes

Tanaka, M., Chikuma, S., & Hara‐Chikuma, M. (2026) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2603334123

Reimagining Cannabidiol Delivery Through Carbon Nanodots

Ibrahim, I., Lawrence, K., Forte, O. A., Naidu, N. C., Huitt, L., Ajibola, N., Xu, J., Boakai, R. K., Mengu, M., Akabanda, F., et al. (2026) · Molecules · doi:10.3390/molecules31193404

Discovery of a Potent, Selective, and Orally Efficacious STAT6 PROTAC for the Treatment of Atopic Dermatitis

Wang, W.-T., Zhao, M., Hu, L., Wang, C., Shen, Z., Jiang, R., Peng, F., Wang, Y., Che, J., Huang, W., et al. (2026) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.6c01208

Skin-resident CXCR6+ memory CD4+ T cells and dendritic cells form dermal perivascular hubs that drive relapse in allergic dermatitis

Asahina, R., Minami, F., Nakamizo, S., Miyake, T., Yonekura, S., Kogame, T., Kanameishi, S., Katsuo, K., Irie, H., Nakajima, S., et al. (2026) · Immunity · doi:10.1016/j.immuni.2026.09.010 · Cited by 1

Protective and pathogenic roles of resident memory T cells in human skin disorders

Watanabe, R. (2019) · Journal of Dermatological Science · doi:10.1016/j.jdermsci.2019.06.001 · Cited by 26

Tissue-Resident Memory T Cells in Skin Barriers

Chen, L., & Shen, Z. (2024) · IntechOpen eBooks · doi:10.5772/intechopen.1004456

Research progress on tissue-resident T cells in inflammatory skin diseases

Xin, T., Chong, Z., Qian, Y., Yan, Y., & Baoxi, W. (2025) · DOAJ (DOAJ: Directory of Open Access Journals) · doi:10.3969/j.issn.1674-8468.2025.10.011

Skin-resident T cells: the ups and downs of on site immunity

Clark, R. A. (2010) · Journal of Investigative Dermatology · doi:10.1038/jid.2009.247 · Cited by 298

Tissue-Resident T Cells: Dynamic Players in Skin Immunity

Mueller, S. N., Zaid, A., & Carbone, F. R. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00332 · Cited by 100