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Early Pleistocene enamel proteome from Dmanisi resolves Stephanorhinus phylogeny

Cappellini, Enrico, Welker, Frido, Pandolfi, Luca, Ramos-Madrigal, Jazmín, Samodova, Diana, Rüther, Patrick L., Fotakis, Anna K., Lyon, David, Moreno-Mayar, J. Víctor, Bukhsianidze, Maia, Rakownikow Jersie-Christensen, Rosa, Mackie, Meaghan, Ginolhac, Aurélien, Ferring, Reid, Tappen, Martha, Palkopoulou, Eleftheria, Dickinson, Marc R., Stafford, Thomas W., Chan, Yvonne L., Götherström, Anders, Nathan, Senthilvel K. S. S., Heintzman, Peter D., Kapp, Joshua D., Kirillova, Irina, Moodley, Yoshan, Agusti, Jordi, Kahlke, Ralf-Dietrich, Kiladze, Gocha, Martínez-Navarro, Bienvenido, Liu, Shanlin, Sandoval Velasco, Marcela, Sinding, Mikkel-Holger S., Kelstrup, Christian D., Allentoft, Morten E., Orlando, Ludovic, Penkman, Kirsty, Shapiro, Beth, Rook, Lorenzo, Dalén, Love, Gilbert, M. Thomas P., Olsen, Jesper V., Lordkipanidze, David, Willerslev, Eske·2019·Nature
DOI 10.1038/s41586-019-1555-yPMC PMC6894936
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  • Enamel has been explored as a well-preserved source of ancient proteins that can be analyzed to enable phylogenetic analysis of extinct animals and humans, as well as identification of sex based on sequence differences in amelogenin.

    “Recently, enamel has been explored as a well-preserved source of ancient proteins that can be analyzed to enable the phylogenetic analysis of extinct animals and humans (71, 72), as well as the identification of sex based on sequence differences in the enamel protein amelogenin (73–75).”

    From Ancient protein analysis in archaeology (2021) · cites this paper as [72]

    The paper’s Abstract reports that ancient enamel proteins preserve phylogenetic information and describes phylogenetic analysis of Dmanisi animal remains. It mentions hominin fossils at the site but does not report a phylogenetic analysis of humans. The sex-identification clause is attached to separate citations (73–75), although this paper also reports identifying male specimens using Y-specific amelogenin peptides. (LLM, conf=0.85)

    Experimental — accuracy not yet measured

  • The paleoproteomic phylogenetic approach has also been applied to extinct faunal taxa, including Stephanorhinus, Macrauchenia and Toxodon, Castoroides ohioensis, and Plesiorycteropus.

    “This approach has also been applied to the study of extinct faunal taxa, including Stephanorhinus (an extinct genus of rhinoceros) (72), Macrauchenia and Toxodon (South American ungulates) (147, 148), Castoroides ohioensis (giant beaver) (149), and Plesiorycteropus (Malagasy aardvark) (150)”

    From Ancient protein analysis in archaeology (2021) · cites this paper as [72]

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Research works printed but not linked: 54

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Authors
Cappellini, E., Welker, F., Pandolfi, L., Ramos-Madrigal, J., Samodova, D., Rüther, P. L., Fotakis, A. K., Lyon, D., Moreno-Mayar, J. V., Bukhsianidze, M., Rakownikow Jersie-Christensen, R., Mackie, M., Ginolhac, A., Ferring, R., Tappen, M., Palkopoulou, E., Dickinson, M. R., Stafford, T. W., Chan, Y. L., Götherström, A., Nathan, S. K. S. S., Heintzman, P. D., Kapp, J. D., Kirillova, I., Moodley, Y., Agusti, J., Kahlke, R.-D., Kiladze, G., Martínez-Navarro, B., Liu, S., Sandoval Velasco, M., Sinding, M.-H. S., Kelstrup, C. D., Allentoft, M. E., Orlando, L., Penkman, K., Shapiro, B., Rook, L., Dalén, L., Gilbert, M. T. P., Olsen, J. V., Lordkipanidze, D., & Willerslev, E.
Venue
Nature
Publisher
Springer Science and Business Media LLC
Published
2019-09-11
Volume
574
Issue
7776
Pages
103-107
ISSN
  • 0028-0836
  • 1476-4687
DOI
10.1038/s41586-019-1555-y
PMC
PMC6894936
Cited by
205
References
9
Language
en
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