Cited by 101COVID-19 Digital Contact TracingMobile Health and mHealth ApplicationsData-Driven Disease Surveillance

Smartphone apps in the COVID-19 pandemic

Open access
Pandit, Jay A., Radin, Jennifer M., Quer, Giorgio, Topol, Eric J.·2022·Nature Biotechnology

Abstract

At the beginning of the COVID-19 pandemic, analog tools such as nasopharyngeal swabs for PCR tests were center stage and the major prevention tactics of masking and physical distancing were a throwback to the 1918 influenza pandemic. Overall, there has been scant regard for digital tools, particularly those based on smartphone apps, which is surprising given the ubiquity of smartphones across the globe. Smartphone apps, given accessibility in the time of physical distancing, were widely used for tracking, tracing and educating the public about COVID-19. Despite limitations, such as concerns around data privacy, data security, digital health illiteracy and structural inequities, there is ample evidence that apps are beneficial for understanding outbreak epidemiology, individual screening and contact tracing. While there were successes and failures in each category, outbreak epidemiology and individual screening were substantially enhanced by the reach of smartphone apps and accessory wearables. Continued use of apps within the digital infrastructure promises to provide an important tool for rigorous investigation of outcomes both in the ongoing outbreak and in future epidemics.

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  • Many remote, site-less trials using wearables were conducted during the COVID-19 pandemic to detect coronavirus.

    “Many remote, site-less trials using wearables were conducted during the COVID-19 pandemic to detect coronavirus 38 .”

    From Multimodal biomedical AI (2022) · cites this paper as [38]

    The Passive screening section (page unavailable) describes several pandemic-era studies and projects using wearables to detect COVID-19, including DETECT and the Stanford Wearables Study. It does not establish that many of these were site-less trials; the trial listed in the References is a study protocol, not evidence that the trial was conducted. (LLM, conf=0.86)

    Experimental — accuracy not yet measured
  • Many mobile apps have been developed using Bluetooth and Wi-Fi technology to understand outbreak epidemiology, individual screening and contact tracing.

    “Many mobile apps have been developed using such technology to understand outbreak epidemiology, individual screening and contact tracing [172–174].”

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Research works printed but not linked: 4

  1. [53]Quer G, The Physiologic Response to COVID-19 Vaccination. medRxiv (2021).
  2. [74]Aravindan A. & Phartiyal S. Bluetooth phone apps for tracking COVID-19 show modest early results. Technology News. Retrieved December 2, 2020 (2020).
  3. [82]Ladyzhets B. We investigated whether digital contact tracing actually worked in the US. MIT Technology Review (2021).
  4. [84]O’Neill PH No, coronavirus apps don’t need 60% adoption to be effective. MIT Technology Review (2020).

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Authors
Pandit, J. A., Radin, J. M., Quer, G., & Topol, E. J.
Affiliations
  • Northwestern University (US)
  • Scripps Research Institute (US)
Corresponding author
Topol, Eric J.
Venue
Nature Biotechnology
Published
2022-06-20
Volume
40
Issue
7
Pages
1013-1022
ISSN
  • 0733-222X (ISSN-L)
  • 1087-0156
  • 1546-1696
OpenAlex
W4283167029
Cited by
101
References
79
Citations by year
2026: 16 · 2025: 18 · 2024: 31 · 2023: 32 · 2022: 4
FWCI
2.68
Type
journal article
Language
en
Open access
Locations
  • Nature Biotechnology (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (publishedVersion)
Funders
  • National Institutes of Health (UL1TR002550)
  • National Center for Advancing Translational Sciences
Topics
  • Physical Sciences › Computer Science › Information Systems › COVID-19 Digital Contact Tracing
  • Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
  • Health Sciences › Medicine › Epidemiology › Data-Driven Disease Surveillance
Keywords
COVID-19 pandemic, mobile application, contact tracing, digital health, data privacy, digital health literacy, wearable devices, outbreak epidemiology, individual screening, structural inequality, pandemic response
MeSH terms
COVID-19, SARS-CoV-2, Humans, Contact Tracing, Pandemics, Mobile Applications

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