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The New Era of Three-Dimensional Histoarchitecture of the Human Endometrium

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Fatty Liver Is an Independent Risk Factor for Delayed Recovery from Anesthesia

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CKIP-1 augments autophagy in steatotic hepatocytes by inhibiting Akt/mTOR signal pathway

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Modeling Alcoholic Liver Disease in a Human Liver-ChipPreprint

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3D reconstruction of human liver tissue at cellular resolution

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Bariatric Surgery - Past and Present

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Can cysteinyl cathepsin activity control diet-induced NAFLD?

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Integration of Pseudotargeted Metabolomics and Microbiomics Reveals That Hugan Tablets Ameliorate NASH with Liver Fibrosis in Mice by Modulating Bile Acid Metabolism via the Gut Microbiome

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LiverMap pipeline for 3D imaging of human liver reveals volumetric spatial dysregulation of cirrhotic vasculobiliary architecturePreprint

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Noninvasive assessment of liver fibrosis in mini pigs using an 18F–AlF-NOTA-RGD2 PET/CT molecular probe

Liu, W., Xu, H., Zhang, H., Xie, M., Liu, Y., Wang, L., Wu, X., Feng, Y., & Chen, K. (2024) · Heliyon · doi:10.1016/j.heliyon.2024.e35502 · Cited by 1

An Open-source Protocol for Deep Learning-based Segmentation of Tubular Structures in 3D Fluorescence Microscopy Images

Velasco, R., Pérez-Gallardo, C., Segovia‐Miranda, F., & Morales-Navarrete, H. A. (2025) · Journal of Visualized Experiments · doi:10.3791/68004 · Cited by 1

Single cell multiomic landscape reveals gene programs driving lipid droplet heterogeneity in hepatic steatosis

Sehrawat, T. S., Cooper, S. A., Navarro‐Corcuera, A., Schulze, R. J., Liu, M., Yaqoob, U., Yeon, Y., Yoon, S., Noh, Y., Meroueh, C., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-39913-6 · Cited by 1

High-definition medicine: modelling NAFLD in 3D

Ray, K. (2019) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-019-0256-1 · Cited by 1

Ursodeoxycholic Acid in Liver Cirrhosis: A Chinese Perspective

Gao, W., Li, Z., Chu, H., Yuan, H., Hu, L., Yao, L., Zhang, L. R., Wang, W., Lin, R., & Yang, L. (2022) · Springer eBooks · doi:10.1007/978-981-19-2615-0_6 · Cited by 1

A novel 3D visualization method in mice identifies the periportal lamellar complex (PLC) as a key regulator of hepatic ductal and neuronal branching morphogenesisPreprint

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Letter to the Editor and Comments on: Intravital dynamic and correlative imaging reveals diffusion-dominated canalicular and flow-augmented ductular bile flux

Brusch, L., Kalaidzidis, Y. L., Meyer, K., Sbalzarini, I. F., & Zerial, M. (2020) · arXiv (Cornell University) · doi:10.48550/arxiv.2012.12319

Early Diagnosis of Non-Alcoholic Steatohepatitis in Patients with Non-Alcoholic Fatty Liver Disease

李, 露. (2022) · Advances in Clinical Medicine · doi:10.12677/acm.2022.122143

Image-based quantification of histological features as a function of spatial location using the Tissue Positioning SystemPreprint

Wang, Y., Rong, R., Wei, Y., Wang, T., Xiao, G., & Zhu, H. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.12.511979

Hep3D: A 3D single-cell digital atlas of the liver to study spatio-temporal tissue architecturePreprint

Martínez, D., Maldonado, V., Pérez, C., Yañez, R., Candia, V., Kalaidzidis, Y. L., Zerial, M., Morales-Navarrete, H. A., & Segovia‐Miranda, F. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.01.21.525037

A Feasibility Study on 3-D Imaging of Intrahepatic Bile Ducts in Patients with Biliary Atresia Using Airy Beam Excited Two-Photon Microscopy

Musha, J., Zhao, Y., Zhao, R., Li, Y., Sun, R., Liu, P., & Zhan, J. (2024) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-024-05090-3

Plasticité épithéliale dans les maladies hépatiques chroniques

Pesic, M., Vallier, L., & Liabeuf, D. (2025) · médecine/sciences · doi:10.1051/medsci/2025089

A novel 3D visualization method in mice identifies the periportal lamellar complex (PLC) as a key regulator of hepatic ductal and neuronal branching morphogenesis

Xu, T., Cao, F., Zhou, R., Chen, Q., Zhong, J., Wang, Y., Xiao, C., Yin, B., Chen, C., & Zhao, C. (2026) · eLife · doi:10.7554/elife.108669.5

Integrating dielectric properties analysis and machine learning for accurate liver cancer identification and infiltration depth prediction

Ye, C., Wang, X. D., Ju, W., Jia, Y., Yu, X., & Han, J. (2025) · Physical and Engineering Sciences in Medicine · doi:10.1007/s13246-025-01656-5

A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching MorphogenesisPreprint

Xu, T., Cao, F., Zhou, R., Chen, Q., Zhong, J., Wang, Y., Xiao, C., Yin, B., Chen, C., & Zhao, C. (2025) · eLife · doi:10.7554/elife.108669.1

Additional file 1 of Normalization of γ-glutamyl transferase levels is associated with better metabolic control in individuals with nonalcoholic fatty liver disease

Ma, Q., Xianhua, L., Shao, C., Lin, Y., Wu, T., Sun, Y., Feng, S., Ye, J., & Zhong, B. (2021) · Figshare · doi:10.6084/m9.figshare.14570383

Quantitative Analysis of Liver Fibrosis Expansion Using 3D-Reconstructed Stained Images and Statistical Modeling

Ueda, R., & Shoji, H. (2025) · Forma · doi:10.55653/forma.2025.001.004

A Novel 3D Visualization Method in Mice Identifies the Periportal Lamellar Complex (PLC) as a Key Regulator of Hepatic Ductal and Neuronal Branching MorphogenesisPreprint

Xu, T., Cao, F., Zhou, R., Chen, Q., Zhong, J. Q., Wang, Y., Xiao, C., Yin, B., Chen, C., & Zhao, C. (2026) · eLife · doi:10.7554/elife.108669.2

Digital modeling of the gallbladder for revealing microanatomical features and optimizing surgical approaches in gallbladder-preserving cholelithotomy

Li, X., Ye, X., Yang, P., Wu, H., Fan, T., Xiao, Z., Jiang, Q., 林, 哲., Peng, S., Huang, T., et al. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2025.1710325

Ultrastructural analysis of transjugular biopsies in MASLD reveals core hepatocellular stress and cytoskeletal adaptations

Ibáñez, L., López, S. A., Cagigal, M. L., Rodriguez, D. R., Catalina, M., Peligros, M. I., Sánchez, Á. P., Collado, A. S., Téllez, L., Llop, E., et al. (2026) · Revista Española de Enfermedades Digestivas · doi:10.17235/reed.2026.11784/2025

GASNet: Progressive Resolution-Aware Supervision and Gabor Guidance for Accurate Liver Vessel Segmentation

Yang, Q., Xu, N., Wang, G. M., Meng, X., Dai, H., Wang, H., Yu, W., & Wang, X. (2025) · IEEE International Conference on Bioinformatics and Biomedicine (BIBM) · doi:10.1109/bibm66473.2025.11355980

Understanding liver and digestive diseases: a paved road to improve diagnosis, management, and treatment

Bergheim, I., Cadranel, J. F. D., Chen, J., Ding, W., Eferl, R., García‐Ruiz, C., Jaeschke, H., Kazerouni, F., Lonardo, A., Mann, D. A., et al. (2026) · Exploration of Digestive Diseases · doi:10.37349/edd.2026.1005110

A multi-structure 3D multiphoton liver microscopy dataset integrating real, physics-based, and GAN-simulated volumes for benchmarking bioimage analysis

Martínez-Torres, D., Bettancourt, N., Vergara-Estrada, J., Almendras-Durán, K., Candia, V., Segovia‐Miranda, F., & Morales-Navarrete, H. A. (2026) · Scientific Data · doi:10.1038/s41597-026-08208-w

High-definition medicine: modelling NAFLD in 3D

Ray, K. (2019) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-019-0256-1 · Cited by 1

3D reconstruction and spatial quantitative analysis of NAFLD

Moser, V., Segovia‐Miranda, F., Morales-Navarrete, H. A., Nehring, S., Schönfels, W. V., Schafmayer, C., Brosch, M., Hampe, J., Kalaidzidis, Y. L., & Zerial, M. (2018) · Zeitschrift für Gastroenterologie · doi:10.1055/s-0037-1612741 · Cited by 1

Three-Dimensional Organoids as a Model to Study Nonalcoholic Fatty Liver Disease

Park, Y., Thadasina, D., Bolujo, I., Isidan, A., Cross-Najafi, A. A., Lopez, K., Li, P., Dahlem, A. M., Kennedy, L. L., Sato, K., et al. (2022) · Seminars in Liver Disease · doi:10.1055/a-1934-5588 · Cited by 13

Modeling nonalcoholic fatty liver disease on a liver lobule chip with dual blood supply

Du, K., Li, S., Li, C., Li, P., Miao, C., Luo, T., Qiu, B., & Ding, W. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.07.013 · Cited by 70

Three-dimensional imaging of cleared human liver tissues reveals extensive fibrosis heterogeneity in non-alcoholic fatty liver disease

Yiğit, B., Özgönül, E., Yaman, O., Ulukan, B., Taş, Y. Ç., Morova, B., Aydın, M., Uysallı, Y., Demirtas, E., Erkan, M., et al. (2022) · Journal of Hepatology · doi:10.1016/s0168-8278(22)01704-4