The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Ca2+ activity signatures of myelin sheath formation and growth in vivo
Open accessAbstract
During myelination, individual oligodendrocytes initially over-produce short myelin sheaths, which are either retracted or stabilized. By live-imaging oligodendrocyte Ca2+ activity in vivo, we find that high-amplitude, long-duration Ca2+ transients in sheaths prefigure retractions, mediated by calpain. Following stabilization, myelin sheaths grow along axons, and we find that higher-frequency Ca2+ transient activity in sheaths precedes faster elongation. Our data implicate local Ca2+ signaling in regulating distinct stages of myelination. The authors live-image zebrafish myelin sheath Ca2+ activity in vivo and find that high-amplitude long-duration Ca2+ transients precede calpain-dependent sheath retractions while frequent low-amplitude short-duration transients drive sheath growth.
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Cites
Ultrasensitive fluorescent proteins for imaging neuronal activity
Chen, T.-W., Wardill, T. J., Sun, Y., Pulver, S. R., Renninger, S. L., Baohan, A., Schreiter, E. R., Kerr, R. A., Orger, M. B., Jayaraman, V., et al. (2013) · Nature · doi:10.1038/nature12354 · Cited by 6,474
Transparent Adult Zebrafish as a Tool for In Vivo Transplantation Analysis
White, R. M., Sessa, A., Burke, C., Bowman, T., LeBlanc, J., Ceol, C., Bourque, C., Dovey, M., Goessling, W., Burns, C. E., et al. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2007.11.002 · Cited by 1,408
Control of local protein synthesis and initial events in myelination by action potentials
Wake, H., Lee, P. R., & Fields, R. D. (2011) · Science · doi:10.1126/science.1206998 · Cited by 636
Synaptic vesicle release regulates myelin sheath number of individual oligodendrocytes in vivo
Mensch, S., Baraban, M., Almeida, R., Czopka, T., Ausborn, J., El Manira, A., & Lyons, D. A. (2015) · Nature Neuroscience · doi:10.1038/nn.3991 · Cited by 398
Self-citationWake, H., Ortiz, F. C., Woo, D. H., Lee, P. R., Angulo, M. C., & Fields, R. D. (2015) · Nature Communications · doi:10.1038/ncomms8844 · Cited by 244
Individual axons regulate the myelinating potential of single oligodendrocytes in vivo
Almeida, R. G., Czopka, T., ffrench-Constant, C., & Lyons, D. A. (2011) · Development · doi:10.1242/dev.071001 · Cited by 214
Self-citationThe molecular physiology of the axo-myelinic synapse
Micu, I., Plemel, J. R., Lachance, C., Proft, J., Jansen, A. J., Cummins, K., van Minnen, J., & Stys, P. K. (2016) · Experimental Neurology · doi:10.1016/j.expneurol.2015.10.006 · Cited by 140
Cited by
Myelin in the Central Nervous System: Structure, Function, and Pathology
Stadelmann, C., Timmler, S., Barrantes-Freer, A., & Simons, M. (2019) · Physiological Reviews · doi:10.1152/physrev.00031.2018 · Cited by 728
Oligodendrocytes in development, myelin generation and beyond
Kuhn, S., Gritti, L., Crooks, D., & Dombrowski, Y. (2019) · Cells · doi:10.3390/cells8111424 · Cited by 625
Spinal cord repair: advances in biology and technology
Courtine, G., & Sofroniew, M. V. (2019) · Nature Medicine · doi:10.1038/s41591-019-0475-6 · Cited by 508
Microglia phagocytose myelin sheaths to modify developmental myelination
Hughes, A. N., & Appel, B. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-0654-2 · Cited by 344
Molecular Control of Oligodendrocyte Development
Elbaz, B., & Popko, B. (2019) · Trends in Neurosciences · doi:10.1016/j.tins.2019.01.002 · Cited by 293
Metadata
- Authors
- Baraban, M., Koudelka, S., & Lyons, D. A.
- Venue
- Nature Neuroscience
- Published
- 2017-12-11
- Volume
- 21
- Issue
- 1
- Pages
- 19-23
- ISSN
- 1097-6256 (ISSN-L)
- 1546-1726
- OpenAlex
- W2773210706
- Cited by
- 193
- References
- 7
- FWCI
- 7.82
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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