Individual axons regulate the myelinating potential of single oligodendrocytes in vivo

The Tol2kit: A multisite gateway‐based construction kit for Tol2 transposon transgenesis constructs

Kwan, K. M., Fujimoto, E., Grabher, C., Mangum, B. D., Hardy, M., Campbell, D. S., Parant, J. M., Yost, H. J., Kanki, J. P., & Chien, C.-B. (2007) · Developmental Dynamics · doi:10.1002/dvdy.21343 · Cited by 1,778 · see citing works

Myelination and support of axonal integrity by glia

Nave, K.-A. (2010) · Nature · doi:10.1038/nature09614 · Cited by 1,062 · see citing works

Axonal Neuregulin-1 Regulates Myelin Sheath Thickness

Michailov, G. V., Sereda, M. W., Brinkmann, B. G., Fischer, T. M., Haug, B., Birchmeier, C., Role, L. W., Lai, C., Schwab, M. H., & Nave, K. (2004) · Science · doi:10.1126/science.1095862 · Cited by 940 · see citing works

Neuregulin-1 Type III Determines the Ensheathment Fate of Axons

Taveggia, C., Zanazzi, G. J., Petrylak, A., Yano, H., D, J. R. M., Einheber, S., Xu, X., Esper, R. M., Loeb, J. A., Shrager, P. G., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.08.017 · Cited by 730 · see citing works

Notch Receptor Activation Inhibits Oligodendrocyte Differentiation

Wang, S., Sdrulla, A. D., diSibio, G., Bush, G., Nofziger, D., Hicks, C. D., Weinmaster, G., & Barres, B. A. (1998) · Neuron · doi:10.1016/s0896-6273(00)80515-2 · Cited by 706 · see citing works

LINGO-1 negatively regulates myelination by oligodendrocytes

Mi, S., Miller, R. H., Lee, X., Scott, M. L., Shulag-Morskaya, S., Shao, Z., Chang, J., Thill, G., Levesque, M., Zhang, M., et al. (2005) · Nature Neuroscience · doi:10.1038/nn1460 · Cited by 628 · see citing works

A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development

Barrès, A., Lazar, M. A., & RAFF, M. C. (1994) · Development · doi:10.1242/dev.120.5.1097 · Cited by 593 · see citing works

Glial cells and the central myelin sheath.

Bunge, R. P. (1968) · Physiological Reviews · doi:10.1152/physrev.1968.48.1.197 · Cited by 539 · see citing works

Clonal analysis of oligodendrocyte development in culture: Evidence for a developmental clock that counts cell divisions

Temple, S., & RAFF, M. C. (1986) · Cell · doi:10.1016/0092-8674(86)90843-3 · Cited by 455 · see citing works

Neuregulin-1/ErbB Signaling Serves Distinct Functions in Myelination of the Peripheral and Central Nervous System

Brinkmann, B. G., Agarwal, A., Sereda, M. W., Garratt, A. N., Müller, T. H., Wende, H., Stassart, R. M., Nawaz, S., Humml, C., Velanac, V., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.06.028 · Cited by 419 · see citing works

In vivo time-lapse imaging shows dynamic oligodendrocyte progenitor behavior during zebrafish development

Kirby, B. B., Takada, N., Latimer, A. J., Shin, J., Carney, T. J., Kelsh, R. N., & Appel, B. (2006) · Nature Neuroscience · doi:10.1038/nn1803 · Cited by 394 · see citing works

Oligodendrocyte wars

Richardson, W. D., Kessaris, N., & Pringle, N. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn1826 · Cited by 385 · see citing works

Myelinated nerve fibres in the CNS

Hildebrand, C., Remahl, S., Persson, H., & Bjartmar, C. (1993) · Progress in Neurobiology · doi:10.1016/0301-0082(93)90015-k · Cited by 376 · see citing works

F3/Contactin Acts as a Functional Ligand for Notch during Oligodendrocyte Maturation

Hu, Q., Ang, B.-T., Karsak, M., Hu, W.-P., Cui, X., Duka, T., Takeda, Y., Chia, W., Sankar, N., Ng, Y., et al. (2003) · Cell · doi:10.1016/s0092-8674(03)00810-9 · Cited by 367 · see citing works

Axonal Control of Oligodendrocyte Development

Barres, B. A., & Raff, M. C. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.6.1123 · Cited by 360 · see citing works

Characterization of myelination in the developing zebrafish

Brösamle, C., & Halpern, M. E. (2002) · Glia · doi:10.1002/glia.10088 · Cited by 327 · see citing works

A G Protein–Coupled Receptor Is Essential for Schwann Cells to Initiate Myelination

Monk, K. R., Naylor, S. G., Glenn, T. D., Mercurio, S., Perlin, J. R., Dominguez, C. X., Moens, C. B., & Talbot, W. S. (2009) · Science · doi:10.1126/science.1173474 · Cited by 326 · see citing works

Negative regulation of central nervous system myelination by polysialylated-neural cell adhesion molecule

Charles, P., Hernandez, M. P., Stankoff, B., Aigrot, M. S., Colin, C., Rougon, G., Zalc, B., & Lubetzki, C. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.100076197 · Cited by 306 · see citing works

Change in the Brain's White Matter

Fields, R. D. (2010) · Science · doi:10.1126/science.1199139 · Cited by 265 · see citing works

Brain neurons which project to the spinal cord in young larvae of the zebrafish

Kimmel, C. B., Powell, S. L., & Metcalfe, W. K. (1982) · Journal of Comparative Neurology · doi:10.1002/cne.902050203 · Cited by 253 · see citing works

Delta-Notch signaling regulates oligodendrocyte specification

Park, H.-C., & Appel, B. (2003) · Development · doi:10.1242/dev.00576 · Cited by 221 · see citing works

Notch1 control of oligodendrocyte differentiation in the spinal cord

Genoud, S., Lappe-Siefke, C., Goebbels, S., Radtke, F., Aguet, M., Scherer, S. S., Suter, U., Nave, K.-A., & Mantei, N. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200202002 · Cited by 211 · see citing works

Growth cone and dendrite dynamics in zebrafish embryos: early events in synaptogenesis imaged in vivo

Jontes, J. D., Buchanan, J., & Smith, S. J. (2000) · Nature Neuroscience · doi:10.1038/72936 · Cited by 208 · see citing works

Pattern of remyelination in the CNS

BLAKEMORE, W. F. (1974) · Nature · doi:10.1038/249577a0 · Cited by 182 · see citing works

Olig1 and Sox10 Interact Synergistically to Drive Myelin Basic Protein Transcription in Oligodendrocytes

Li, H., Lu, Y., Smith, H., & Richardson, W. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4456-07.2007 · Cited by 180 · see citing works

Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons

Lyons, D. A., Naylor, S. G., Scholze, A. R., & Talbot, W. S. (2009) · Nature Genetics · doi:10.1038/ng.376 · Cited by 176 · see citing works

Polysialylated Neural Cell Adhesion Molecule-Positive CNS Precursors Generate Both Oligodendrocytes and Schwann Cells to Remyelinate the CNS after Transplantation

Keirstead, H. S., Ben‐Hur, T., Rogister, B., O'Leary, M. T., Dubois-Dalcq, M. E., & Blakemore, W. F. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-17-07529.1999 · Cited by 175 · see citing works

NGF Regulates the Expression of Axonal LINGO-1 to Inhibit Oligodendrocyte Differentiation and Myelination

Lee, X., Yang, Z., Shao, Z., Rosenberg, S., Levesque, M., Pepinsky, R. B., Qiu, M. S., Miller, R. H., Chan, J. R., & Mi, S. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4175-06.2007 · Cited by 166 · see citing works

Glial cells are increased proportionally in transgenic optic nerves with increased numbers of axons

Burne, J. F., Staple, J., & RAFF, M. C. (1996) · Journal of Neuroscience · doi:10.1523/jneurosci.16-06-02064.1996 · Cited by 150 · see citing works

A genetic screen identifies genes essential for development of myelinated axons in zebrafish.

Pogoda, H.-M., Sternheim, N., Lyons, D., Diamond, B., Hawkins, T. A., Woods, I., Bhatt, D. H., Franzini-armstrong, C., Dominguez, C., Arana, N., et al. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.06.021 · Cited by 135 · see citing works

Jagged2a-Notch Signaling Mediates Cell Fate Choice in the Zebrafish Pronephric Duct

Ma, M., & Jiang, Y. (2007) · PLoS Genetics · doi:10.1371/journal.pgen.0030018 · Cited by 134 · see citing works

Cultured oligodendrocytes mimic in vivo phenotypic characteristics: Cell shape, expression of myelin-specific antigens, and membrane production

Knapp, P. E., Bartlett, W., & Skoff, R. P. (1987) · Developmental Biology · doi:10.1016/0012-1606(87)90238-7 · Cited by 133 · see citing works

Visualization of myelination in GFP‐transgenic zebrafish

Jung, S., Kim, S., Chung, A., Kim, H., So, J., Ryu, J.-H., Park, H., & Kim, C. (2009) · Developmental Dynamics · doi:10.1002/dvdy.22166 · Cited by 128 · see citing works

Relation between axons and oligodendroglial cells during initial myelination I. The glial unit

Remahl, S., & Hildebrand, C. (1990) · Journal of Neurocytology · doi:10.1007/bf01188401 · Cited by 124 · see citing works

Oligodendrocyte Specification in Zebrafish Requires Notch-Regulated Cyclin-Dependent Kinase Inhibitor Function

Park, H., Boyce, J., Shin, J., & Appel, B. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0981-05.2005 · Cited by 117 · see citing works

Phosphatidylinositol 4,5-Bisphosphate-Dependent Interaction of Myelin Basic Protein with the Plasma Membrane in Oligodendroglial Cells and Its Rapid Perturbation by Elevated Calcium

Nawaz, S., Kippert, A., Saab, A. S., Werner, H. B., Lang, T., Nave, K.-A., & Simons, M. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.3955-08.2009 · Cited by 116 · see citing works

The conduction properties of axons in central white matter

Waxman, S. G., & Swadlow, H. A. (1977) · Progress in Neurobiology · doi:10.1016/0301-0082(77)90009-0 · Cited by 109 · see citing works

Two-tier transcriptional control of oligodendrocyte differentiation

Li, H., He, Y., Richardson, W., & Casaccia, P. (2009) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.08.004 · Cited by 98 · see citing works

Morphological and electrical properties of oligodendrocytes in the white matter of the corpus callosum and cerebellum

Bakiri, Y., Káradóttir, R. T., Cossell, L., & Attwell, D. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.201376 · Cited by 97 · see citing works

Down-regulation of Polysialic Acid Is Required for Efficient Myelin Formation

Fewou, S. N., Ramakrishnan, H., Büssow, H., Gieselmann, V., & Eckhardt, M. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m610797200 · Cited by 94 · see citing works

KBP is essential for axonal structure, outgrowth and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome

Lyons, D. A., Naylor, S. G., Mercurio, S., Dominguez, C. X., & Talbot, W. S. (2008) · Development · doi:10.1242/dev.012377 · Cited by 91 · see citing works

Zebrafish deadly seven Functions in Neurogenesis

Gray, M. E., Moens, C. B., Amacher, S. L., Eisen, J. S., & Beattie, C. E. (2001) · Developmental Biology · doi:10.1006/dbio.2001.0381 · Cited by 86 · see citing works

Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects

Buckley, C. E., Marguerie, A., Roach, A. G., Goldsmith, P., Fleming, A., ALDERTON, W. K., & Franklin, R. J. M. (2010) · Neuropharmacology · doi:10.1016/j.neuropharm.2010.04.014 · Cited by 80 · see citing works

Down-regulation of the axonal polysialic acid–neural cell adhesion molecule expression coincides with the onset of myelination in the human fetal forebrain

Jakovčevski, I., Mo, Z., & Zečević, N. (2007) · Neuroscience · doi:10.1016/j.neuroscience.2007.07.044 · Cited by 78 · see citing works

Rat Optic Nerve Oligodendrocytes Develop in the Absence of Viable Retinal Ganglion Cell Axons

Ueda, H., Levine, J. M., Miller, R. H., & Trapp, B. D. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.6.1365 · Cited by 65 · see citing works

A screen for mutations in zebrafish that affect myelin gene expression in Schwann cells and oligodendrocytes.

Kazakova, N., Li, H., Mora, A., Jessen, K., Mirsky, R., Richardson, W., & Smith, H. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.03.020 · Cited by 58 · see citing works

Mutations in deadly seven/notch1a Reveal Developmental Plasticity in the Escape Response Circuit

Liu, K. S., Gray, M., Otto, S. J., Fetcho, J., & Beattie, C. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-22-08159.2003 · Cited by 55 · see citing works

HoxGene Misexpression and Cell-Specific Lesions Reveal Functionality of Homeotically Transformed Neurons

Hale, M. E., Kheirbek, M. A., Schriefer, J. E., & Prince, V. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5624-03.2004 · Cited by 38 · see citing works

Identification of genes expressed by zebrafish oligodendrocytes using a differential microarray screen

Takada, N., & Appel, B. (2010) · Developmental Dynamics · doi:10.1002/dvdy.22338 · Cited by 35 · see citing works

Untitled work

Rinaman (1998) · doi:10.1002/(sici)1096-9861(19980914)399:1

Untitled work

Goodrum (2000) · doi:10.1002/(sici)1097-4547(20000215)59:4

Myelination of the Nervous System: Mechanisms and Functions

Nave, K., & Werner, H. B. (2014) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100913-013101 · Cited by 1,000 · see citing works

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

Young, K. M., Psachoulia, K., Tripathi, R. B., Dunn, S.-J., Cossell, L., Attwell, D., Tohyama, K., & Richardson, W. D. (2013) · Neuron · doi:10.1016/j.neuron.2013.01.006 · Cited by 872 · see citing works

Oligodendrocytes in development, myelin generation and beyond

Kuhn, S., Gritti, L., Crooks, D., & Dombrowski, Y. (2019) · Cells · doi:10.3390/cells8111424 · Cited by 625 · see citing works

Synaptic vesicle release regulates myelin sheath number of individual oligodendrocytes in vivo

Mensch, S., Baraban, M., Almeida, R., Czopka, T., Ausborn, J., El Manira, A., & Lyons, D. A. (2015) · Nature Neuroscience · doi:10.1038/nn.3991 · Cited by 398 · see citing works

Individual Oligodendrocytes Have Only a Few Hours in which to Generate New Myelin Sheaths In Vivo

Czopka, T., ffrench‐Constant, C., & Lyons, D. A. (2013) · Developmental Cell · doi:10.1016/j.devcel.2013.05.013 · Cited by 332 · see citing works

Dynamics and Mechanisms of CNS Myelination

Bercury, K. K., & Macklin, W. B. (2015) · Developmental Cell · doi:10.1016/j.devcel.2015.01.016 · Cited by 320 · see citing works

Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation

Marisca, R., Hoche, T., Agirre, E., Hoodless, L. J., Barkey, W., Auer, F., Castelo‐Branco, G., & Czopka, T. (2020) · Nature Neuroscience · doi:10.1038/s41593-019-0581-2 · Cited by 246 · see citing works

Regulation of conduction time along axons

Seidl, A. H. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.06.047 · Cited by 231 · see citing works

On Myelinated Axon Plasticity and Neuronal Circuit Formation and Function

Almeida, R. G., & Lyons, D. A. (2017) · The Journal of Neuroscience · doi:10.1523/jneurosci.3185-16.2017 · Cited by 221 · see citing works

How Schwann Cells Sort Axons

Feltri, M. L., Poitelon, Y., & Previtali, S. C. (2015) · The Neuroscientist · doi:10.1177/1073858415572361 · Cited by 205 · see citing works

Ca2+ activity signatures of myelin sheath formation and growth in vivo

Baraban, M., Koudelka, S., & Lyons, D. A. (2017) · Nature Neuroscience · doi:10.1038/s41593-017-0040-x · Cited by 193 · see citing works

Regulation of developing myelin sheath elongation by oligodendrocyte calcium transients in vivo

Krasnow, A. M., Ford, M. C., Valdivia, L. E., Wilson, S. W., & Attwell, D. (2017) · Nature Neuroscience · doi:10.1038/s41593-017-0031-y · Cited by 182 · see citing works

Individual Neuronal Subtypes Exhibit Diversity in CNS Myelination Mediated by Synaptic Vesicle Release

Koudelka, S., Voas, M. G., Almeida, R., Baraban, M., Soetaert, J., Meyer, M. P., Talbot, W. S., & Lyons, D. A. (2016) · Current Biology · doi:10.1016/j.cub.2016.03.070 · Cited by 162 · see citing works

Hypomyelinating leukodystrophies — unravelling myelin biology

Wolf, N. I., ffrench‐Constant, C., & van der Knaap, M. S. (2020) · Nature Reviews Neurology · doi:10.1038/s41582-020-00432-1 · Cited by 164 · see citing works

Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis

Cunha, M. I., Su, M., Cantuti-Castelvetri, L., Müller, S. A., Schifferer, M., Djannatian, M., Alexopoulos, I., van der Meer, F., Winkler, A., van Ham, T. J., et al. (2020) · Journal of Experimental Medicine · doi:10.1084/jem.20191390 · Cited by 160 · see citing works

Intrinsic and adaptive myelination—A sequential mechanism for smart wiring in the brain

Bechler, M. E., Swire, M., & ffrench‐Constant, C. (2017) · Developmental Neurobiology · doi:10.1002/dneu.22518 · Cited by 149 · see citing works

The adhesion GPCR Gpr56 regulates oligodendrocyte development via interactions with Gα12/13 and RhoA

Ackerman, S. D., Garcia, C. M., Piao, X., Gutmann, D. H., & Monk, K. R. (2015) · Nature Communications · doi:10.1038/ncomms7122 · Cited by 149 · see citing works

Glial Cell Development and Function in ZebrafishPreprint

Lyons, D. A., & Talbot, W. S. (2014) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020586 · Cited by 143 · see citing works

New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination

Neely, S. A., Williamson, J. M., Klingseisen, A., Zoupi, L., Early, J. J., Williams, A., & Lyons, D. A. (2022) · Nature Neuroscience · doi:10.1038/s41593-021-01009-x · Cited by 132 · see citing works

Olig1 Function Is Required for Oligodendrocyte Differentiation in the Mouse Brain

Dai, J., Bercury, K., Ahrendsen, J. T., & Macklin, W. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.4962-14.2015 · Cited by 108 · see citing works

A Macrophage Response to Mycobacterium leprae Phenolic Glycolipid Initiates Nerve Damage in Leprosy

Madigan, C. A., Cambier, C. J., Kelly‐Scumpia, K. M., Scumpia, P. O., Cheng, T., Zailaa, J., Bloom, B. R., Moody, D. B., Smale, S. T., Sagasti, A., et al. (2017) · Cell · doi:10.1016/j.cell.2017.07.030 · Cited by 126 · see citing works

Evidence for Myelin Sheath Remodeling in the CNS Revealed by In Vivo Imaging

Auer, F., Vagionitis, S., & Czopka, T. (2018) · Current Biology · doi:10.1016/j.cub.2018.01.017 · Cited by 112 · see citing works

Oligodendrocytes in a Nutshell

Michalski, J., & Kothary, R. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00340 · Cited by 117 · see citing works

Spinal motor neurons are regenerated after mechanical lesion and genetic ablation in larval zebrafish

Ohnmacht, J., Yang, Y., Maurer, G. W., Barreiro‐Iglesias, A., Tsarouchas, T. M., Wehner, D., Sieger, D., Becker, C. G., & Becker, T. (2016) · Development · doi:10.1242/dev.129155 · Cited by 110 · see citing works

Rapid clearance of cellular debris by microglia limits secondary neuronal cell death after brain injury <i>in vivo</i>

Herzog, C., Pons Garcia, L., Keatinge, M., Greenald, D., Moritz, C., Peri, F., & Herrgen, L. (2019) · Development · doi:10.1242/dev.174698 · Cited by 106 · see citing works

Remyelination reporter reveals prolonged refinement of spontaneously regenerated myelin

Powers, B. E., Sellers, D. L., Lovelett, E. A., Cheung, W., Aalami, S., Zapertov, N., Maris, D. O., & Horner, P. J. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1210293110 · Cited by 105 · see citing works

Axonal selection and myelin sheath generation in the central nervous system

Simons, M., & Lyons, D. A. (2013) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2013.04.007 · Cited by 102 · see citing works

Transgenic fluorescent zebrafish lines that have revolutionized biomedical research

Choe, C. P., Choi, S., Kee, Y., Kim, J. M., Kim, S.-H., Lee, Y., Park, H., & Ro, H. (2021) · Laboratory Animal Research · doi:10.1186/s42826-021-00103-2 · Cited by 96 · see citing works

iPSC-derived myelinoids to study myelin biology of humans

James, O. G., Selvaraj, B. T., Magnani, D., Burr, K., Connick, P., Barton, S. K., Vasistha, N. A., Hampton, D. W., Story, D., Śmigiel, R. S., et al. (2021) · Developmental Cell · doi:10.1016/j.devcel.2021.04.006 · Cited by 93 · see citing works

Low‐intensity transcranial magnetic stimulation promotes the survival and maturation of newborn oligodendrocytes in the adult mouse brain

Cullen, C. L., Senesi, M., Tang, A. D., Clutterbuck, M. T., Auderset, L., O'Rourke, M. E., Rodger, J., & Young, K. M. (2019) · Glia · doi:10.1002/glia.23620 · Cited by 89 · see citing works

Endothelin signalling mediates experience-dependent myelination in the CNS

Swire, M., Kotelevtsev, Y. V., Webb, D. J., Lyons, D. A., & ffrench‐Constant, C. (2019) · eLife · doi:10.7554/elife.49493 · Cited by 90 · see citing works

Zebrafish as a model to investigate CNS myelination

Preston, M., & Macklin, W. B. (2014) · Glia · doi:10.1002/glia.22755 · Cited by 89 · see citing works

In vivo zebrafish assays for analyzing drug toxicity

Raldúa, D., & Piña, B. (2014) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1517/17425255.2014.896339 · Cited by 87 · see citing works

An automated high-resolution in vivo screen in zebrafish to identify chemical regulators of myelination

Early, J. J., Marshall-Phelps, K. L., Williamson, J., Swire, M., Kamadurai, H., Muskavitch, M. A. T., & Lyons, D. A. (2018) · eLife · doi:10.7554/elife.35136 · Cited by 81 · see citing works

Myelin plasticity in adulthood and aging

Chapman, T. W., & Hill, R. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.134645 · Cited by 85 · see citing works

Serotonin Promotes Development and Regeneration of Spinal Motor Neurons in Zebrafish

Barreiro‐Iglesias, A., Mysiak, K. S., Scott, A. L. M., Reimer, M. M., (杨宇婕), Y. Y., Becker, C. G., & Becker, T. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.09.050 · Cited by 82 · see citing works

Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS

Djannatian, M., Timmler, S., Arends, M., Luckner, M., Weil, M., Alexopoulos, I., Snaidero, N., Schmid, B., Misgeld, T., Möbius, W., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12789-z · Cited by 81 · see citing works

Myelination generates aberrant ultrastructure that is resolved by microglia

Djannatian, M., Radha, S., Weikert, U., Safaiyan, S., Wrede, C., Deichsel, C., Kislinger, G., Rhomberg, A., Ruhwedel, T., Campbell, D. S., et al. (2022) · The Journal of Cell Biology · doi:10.1083/jcb.202204010 · Cited by 81 · see citing works

Adaptive myelination from fish to man

Baraban, M., Mensch, S., & Lyons, D. A. (2015) · Brain Research · doi:10.1016/j.brainres.2015.10.026 · Cited by 82 · see citing works

Axonal Regulation of Central Nervous System Myelination: Structure and Function

Klingseisen, A., & Lyons, D. A. (2017) · The Neuroscientist · doi:10.1177/1073858417703030 · Cited by 77 · see citing works

Zebrafish regenerate full thickness optic nerve myelin after demyelination, but this fails with increasing age

Muenzel, E. J., Becker, C. G., Becker, T., & Williams, A. (2014) · Acta Neuropathologica Communications · doi:10.1186/preaccept-5005406801297956 · Cited by 77 · see citing works

The Role of Oligodendroglial Dysfunction in Amyotrophic Lateral Sclerosis

Nonneman, A., Robberecht, W., & Bosch, L. V. D. (2014) · Neurodegenerative Disease Management · doi:10.2217/nmt.14.21 · Cited by 69 · see citing works

Evolution of rapid nerve conduction

Castelfranco, A. M., & Hartline, D. K. (2016) · Brain Research · doi:10.1016/j.brainres.2016.02.015 · Cited by 64 · see citing works

Dynein/dynactin is necessary for anterograde transport of Mbp mRNA in oligodendrocytes and for myelination in vivo

Herbert, A. L., Fu, M., Drerup, C. M., Gray, R. S., Harty, B. L., Ackerman, S. D., O’Reilly-Pol, T., Johnson, S. L., Nechiporuk, A. V., Barres, B. A., et al. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1711088114 · Cited by 67 · see citing works

The scales and tales of myelination: using zebrafish and mouse to study myelinating glia

Ackerman, S. D., & Monk, K. R. (2015) · Brain Research · doi:10.1016/j.brainres.2015.10.011 · Cited by 65 · see citing works

Contact-Mediated Inhibition Between Oligodendrocyte Progenitor Cells and Motor Exit Point Glia Establishes the Spinal Cord Transition Zone

Smith, C. J., Morris, A. D., Welsh, T. G., & Kucenas, S. (2014) · PLoS Biology · doi:10.1371/journal.pbio.1001961 · Cited by 64 · see citing works

Myelination of Neuronal Cell Bodies when Myelin Supply Exceeds Axonal Demand

Almeida, R., Pan, S., Marshall-Phelps, K. L., Williamson, J., Early, J. J., Czopka, T., Klingseisen, A., Chan, J. R., & Lyons, D. A. (2018) · Current Biology · doi:10.1016/j.cub.2018.02.068 · Cited by 58 · see citing works

Myelination of Axons Corresponds with Faster Transmission Speed in the Prefrontal Cortex of Developing Male Rats

McDougall, S., Riad, W. V., Silva-Gotay, A., Tavares, E. R., Harpalani, D., Li, G., & Richardson, H. N. (2018) · eNeuro · doi:10.1523/eneuro.0203-18.2018 · Cited by 54 · see citing works

The Initial Myelination in the Central Nervous System

Yu, Q., Guan, T., Guo, Y., & Kong, J. (2023) · ASN NEURO · doi:10.1177/17590914231163039 · Cited by 56 · see citing works

Insights into mechanisms of central nervous system myelination using zebrafish

Czopka, T. (2015) · Glia · doi:10.1002/glia.22897 · Cited by 50 · see citing works

Organization of the gravity-sensing system in zebrafish

Liu, Z., Hildebrand, D. G. C., Morgan, J. L., Jia, Y., Slimmon, N., & Bagnall, M. W. (2022) · Nature Communications · doi:10.1038/s41467-022-32824-w · Cited by 51 · see citing works

Drug discovery for remyelination and treatment of MS

Marshall-Phelps, K. L., Early, J. J., & Lyons, D. A. (2017) · Glia · doi:10.1002/glia.23166 · Cited by 48 · see citing works

Developmental pruning of early-stage myelin segments during CNS myelination in vivo

Liu, P., Du, J., & He, C. (2013) · Cell Research · doi:10.1038/cr.2013.62 · Cited by 49 · see citing works

Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43

Heo, D., Ling, J. P., Molina-Castro, G. C., Langseth, A. J., Waisman, A., Nave, K., Möbius, W., Wong, P. C., & Bergles, D. E. (2022) · eLife · doi:10.7554/elife.75230 · Cited by 47 · see citing works

A zebrafish model of X-linked adrenoleukodystrophy recapitulates key disease features and demonstrates a developmental requirement for abcd1 in oligodendrocyte patterning and myelination

Strachan, L. R., Stevenson, T. J., Freshner, B., Keefe, M. D., Miranda Bowles, D., & Bonkowsky, J. L. (2017) · Human Molecular Genetics · doi:10.1093/hmg/ddx249 · Cited by 46 · see citing works

Río‐Hortega's drawings revisited with fluorescent protein defines a cytoplasm‐filled channel system of CNS myelin

Edgar, J. M., McGowan, E., Chapple, K. J., Möbius, W., Lemgruber, L., Insall, R. H., Nave, K., & Boullerne, A. I. (2021) · Journal of Anatomy · doi:10.1111/joa.13577 · Cited by 46 · see citing works

Regulating Axonal Responses to Injury: The Intersection between Signaling Pathways Involved in Axon Myelination and The Inhibition of Axon Regeneration

Rao, S. N. R., & Pearse, D. D. (2016) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2016.00033 · Cited by 44 · see citing works

Regeneration of myelin sheaths of normal length and thickness in the zebrafish CNS correlates with growth of axons in caliber

Karttunen, M. J., Czopka, T., Goedhart, M., Early, J. J., & Lyons, D. A. (2017) · PLoS ONE · doi:10.1371/journal.pone.0178058 · Cited by 44 · see citing works

Oligodendrocyte Neurofascin Independently Regulates Both Myelin Targeting and Sheath Growth in the CNS

Klingseisen, A., Ristoiu, A.-M., Kegel, L., Sherman, D. L., Rubio-Brotons, M., Almeida, R., Koudelka, S., Benito-Kwiecinski, S. K., Poole, R. J., Brophy, P., et al. (2019) · Developmental Cell · doi:10.1016/j.devcel.2019.10.016 · Cited by 45 · see citing works

New Insights into Signaling During Myelination in Zebrafish

Raphael, A. R., & Talbot, W. S. (2011) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/b978-0-12-385975-4.00007-3 · Cited by 42 · see citing works

On the resemblance of synapse formation and CNS myelination

Almeida, R., & Lyons, D. A. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.08.062 · Cited by 41 · see citing works

Architecting the myelin landscape

Osso, L. A., & Chan, J. R. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.06.005 · Cited by 40 · see citing works

Oligodendrocyte Development in the Absence of Their Target Axons In Vivo

Almeida, R., & Lyons, D. A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0164432 · Cited by 39 · see citing works

Jmy regulates oligodendrocyte differentiation via modulation of actin cytoskeleton dynamics

Azevedo, M. M., Domingues, H. S., Cordelières, F. P., Sampaio, P., Seixas, A. I., & Relvas, J. B. (2018) · Glia · doi:10.1002/glia.23342 · Cited by 38 · see citing works

Fast, accurate, and versatile data analysis platform for the quantification of molecular spatiotemporal signals

Mi, X., Chen, A., Duarte, D., Carey, E. M., Taylor, C. R., Braaker, P. N., Bright, M., Almeida, R., Lim, J.-X., Ruetten, V. M. S., et al. (2025) · Cell · doi:10.1016/j.cell.2025.03.012 · Cited by 38 · see citing works

Diffusion tensor imaging of the corpus callosum in healthy aging: Investigating higher order polynomial regression modelling

Pietrasik, W., Cribben, I., Olsen, F., Huang, Y., & Malykhin, N. V. (2020) · NeuroImage · doi:10.1016/j.neuroimage.2020.116675 · Cited by 36 · see citing works

The Akt-mTOR Pathway Drives Myelin Sheath Growth by Regulating Cap-Dependent Translation

Fedder-Semmes, K. N., & Appel, B. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0783-21.2021 · Cited by 34 · see citing works

Intersectional Gene Expression in Zebrafish Using the Split KalTA4 System

Almeida, R., & Lyons, D. A. (2015) · Zebrafish · doi:10.1089/zeb.2015.1086 · Cited by 35 · see citing works

Light sheet microscopy with acoustic sample confinement

Yang, Z., Marshall-Phelps, K. L., Qiu, Y., Somorjai, I., Wijesinghe, P., Nylk, J., Cochran, S., Spalding, G. C., Lyons, D. A., & Dholakia, K. (2019) · Nature Communications · doi:10.1038/s41467-019-08514-5 · Cited by 33 · see citing works

Neuronal activity disrupts myelinated axon integrity in the absence of NKCC1b

Marshall-Phelps, K. L., Kegel, L., Baraban, M., Ruhwedel, T., Almeida, R., Rubio-Brotons, M., Klingseisen, A., Benito-Kwiecinski, S. K., Early, J. J., Bin, J. M., et al. (2020) · The Journal of Cell Biology · doi:10.1083/jcb.201909022 · Cited by 33 · see citing works

Integrin-Linked Kinase Regulates Process Extension in Oligodendrocytes via Control of Actin Cytoskeletal Dynamics

O’Meara, R. W., Michalski, J., Anderson, C., Bhanot, K., Rippstein, P. U., & Kothary, R. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.5582-12.2013 · Cited by 33 · see citing works

Neuronal labeling patterns in the spinal cord of adult transgenic Zebrafish

Stil, A., & Drapeau, P. (2015) · Developmental Neurobiology · doi:10.1002/dneu.22350 · Cited by 33 · see citing works

A retroviral link to vertebrate myelination through retrotransposon-RNA-mediated control of myelin gene expression

Ghosh, T., Almeida, R., Zhao, C., Mannioui, A., Martin, E., Fleet, A., Chen, C. Z.-Y., Assinck, P., Ellams, S., González, G. A., et al. (2024) · Cell · doi:10.1016/j.cell.2024.01.011 · Cited by 35 · see citing works

Developmental Neurotoxicity of the Harmful Algal Bloom Toxin Domoic Acid: Cellular and Molecular Mechanisms Underlying Altered Behavior in the Zebrafish Model

Panlilio, J. M., Aluru, N., & Hahn, M. E. (2020) · Environmental Health Perspectives · doi:10.1289/ehp6652 · Cited by 31 · see citing works

Analysis of myelinated axon formation in zebrafish

D’Rozario, M., Monk, K. R., & Petersen, S. C. (2016) · Methods in cell biology · doi:10.1016/bs.mcb.2016.08.001 · Cited by 32 · see citing works

In vivo imaging of Mauthner axon regeneration, remyelination and synapses re-establishment after laser axotomy in zebrafish larvae

Hu, B., Chen, M., Huang, Y., Huang, Y., Wu, Y., Yin, W., Li, L., & Hu, B. (2017) · Experimental Neurology · doi:10.1016/j.expneurol.2017.10.028 · Cited by 31 · see citing works

Identification of 3′ UTR motifs required for mRNA localization to myelin sheaths in vivo

Yergert, K. M., Doll, C. A., O’Rourke, R., Hines, J. H., & Appel, B. (2021) · PLoS Biology · doi:10.1371/journal.pbio.3001053 · Cited by 31 · see citing works

Imaging Myelination In Vivo Using Transparent Animal Models

Bin, J. M., & Lyons, D. A. (2016) · Brain Plasticity · doi:10.3233/bpl-160029 · Cited by 31 · see citing works

Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish

Brun, N. R., Panlilio, J. M., Zhang, K., Zhao, Y., Ivashkin, E. G., Stegeman, J. J., & Goldstone, J. V. (2021) · Communications Biology · doi:10.1038/s42003-021-02626-9 · Cited by 30 · see citing works

Developmental Changes in Oligodendrocyte Genesis, Myelination, and Associated Behavioral Dysfunction in a Rat Model of Intra-generational Protein Malnutrition

Patro, N., Naik, A. A., & Patro, I. K. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1065-1 · Cited by 30 · see citing works

Glutamate Signaling via the AMPAR Subunit GluR4 Regulates Oligodendrocyte Progenitor Cell Migration in the Developing Spinal Cord

Piller, M., Werkman, I. L., Brown, R. I., Latimer, A. J., & Kucenas, S. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.2562-20.2021 · Cited by 30 · see citing works

Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish

Wu, Y., & Hu, B. (2013) · Experimental Neurology · doi:10.1016/j.expneurol.2013.11.012 · Cited by 30 · see citing works

Bi‐allelic VPS16 variants limit HOPS/CORVET levels and cause a mucopolysaccharidosis‐like disease

Sofou, K., Meier, K., Sanderson, L. E., Kaminski, D., Montoliu‐Gaya, L., Samuelsson, E., Blomqvist, M., Agholme, L., Gärtner, J., Mühlhausen, C., et al. (2021) · EMBO Molecular Medicine · doi:10.15252/emmm.202013376 · Cited by 29 · see citing works

The Neuromodulator Adenosine Regulates Oligodendrocyte Migration at Motor Exit Point Transition Zones

Fontenas, L., Welsh, T. G., Piller, M., Coughenour, P., Gandhi, A. V., Prober, D. A., & Kucenas, S. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.03.013 · Cited by 28 · see citing works

The RNA binding protein fragile X mental retardation protein promotes myelin sheath growth

Doll, C. A., Yergert, K. M., & Appel, B. (2019) · Glia · doi:10.1002/glia.23731 · Cited by 27 · see citing works

A critical role for miR-184 in the fate determination of oligodendrocytes

Afrang, N., Tavakoli, R., Tasharrofi, N., Alian, A., Sohi, A. N., Kabiri, M., Fathi‐Roudsari, M., Zomorrod, M. S., Rajaei, F., Soleimani, M., et al. (2019) · Stem Cell Research & Therapy · doi:10.1186/s13287-019-1208-y · Cited by 27 · see citing works

In vivo identification of small molecules mediating Gpr126/Adgrg6 signaling during Schwann cell development

Bradley, E. C., Cunningham, R. L., Wilde, C., Morgan, R. K., Klug, E. A., Letcher, S. M., Schöneberg, T., Monk, K. R., Liebscher, I., & Petersen, S. C. (2019) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.14233 · Cited by 27 · see citing works

Motor Exit Point (MEP) Glia: Novel Myelinating Glia That Bridge CNS and PNS Myelin

Fontenas, L., & Kucenas, S. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00333 · Cited by 26 · see citing works

Thyroid hormone deficiency during zebrafish development impairs central nervous system myelination

Farías-Serratos, B. M., Lazcano, I., Villalobos, P., Darras, V., & Orozco, A. (2021) · PLoS ONE · doi:10.1371/journal.pone.0256207 · Cited by 26 · see citing works

A novel model of demyelination and remyelination in a GFP-transgenic zebrafish

Fang, Y., Lei, X., Li, X., Chen, Y., Xu, F., Feng, X., Wei, S., & Li, Y. (2014) · Biology Open · doi:10.1242/bio.201410736 · Cited by 26 · see citing works

N-Cadherin is Involved in Neuronal Activity-Dependent Regulation of Myelinating Capacity of Zebrafish Individual Oligodendrocytes In Vivo

Chen, M., Xu, Y., Huang, R., Huang, Y., Ge, S., & Hu, B. (2016) · Molecular Neurobiology · doi:10.1007/s12035-016-0233-4 · Cited by 26 · see citing works

Reactive oligodendrocyte progenitor cells (re-)myelinate the regenerating zebrafish spinal cord

Tsata, V., Kroehne, V., Wehner, D., Rost, F., Lange, C. M., Hoppe, C., Kurth, T., Reinhardt, S., Petzold, A., Dahl, A., et al. (2020) · Development · doi:10.1242/dev.193946 · Cited by 25 · see citing works

Proteome Profile of Myelin in the Zebrafish Brain

Siems, S. B., Jahn, O., Hoodless, L. J., Jung, R. B., Hesse, D., Möbius, W., Czopka, T., & Werner, H. B. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.640169 · Cited by 24 · see citing works

Early myelination involves the dynamic and repetitive ensheathment of axons which resolves through a low and consistent stabilization rate

Almeida, A. R., & Macklin, W. B. (2023) · eLife · doi:10.7554/elife.82111 · Cited by 24 · see citing works

Myelin basic protein mRNA levels affect myelin sheath dimensions, architecture, plasticity, and density of resident glial cells

Bagheri, H., Friedman, H. C., Hadwen, A., Jarweh, C., Cooper, E., Oprea, L., Guerrier, C., Khadra, A., Collin, A., Cohen‐Adad, J., et al. (2024) · Glia · doi:10.1002/glia.24589 · Cited by 23 · see citing works

Isolation and Culture of Oligodendrocytes

Weil, M., Schulz-Ëberlin, G., Mukherjee, C., Kuo, W. P., Schäfer, I., Müller, C., & Simons, M. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9072-6_5 · Cited by 23 · see citing works

Uncovering the biology of myelin with optical imaging of the live brain

Hill, R., & Grutzendler, J. (2019) · Glia · doi:10.1002/glia.23635 · Cited by 22 · see citing works

Emerging concepts in oligodendrocyte and myelin formation, inputs from the zebrafish model

Masson, M. L. P., & Nait‐Oumesmar, B. (2023) · Glia · doi:10.1002/glia.24336 · Cited by 22 · see citing works

Label-free adaptive optics single-molecule localization microscopy for whole zebrafish

Park, S., Jo, Y., Kang, M., Hong, J. H., Ko, S., Kim, S., Park, S., Park, H., Shim, S., & Choi, W. (2023) · Nature Communications · doi:10.1038/s41467-023-39896-2 · Cited by 22 · see citing works

A novel myelin protein zero transgenic zebrafish designed for rapid readout of in vivo myelination

Preston, M., Finseth, L. T., Bourne, J. N., & Macklin, W. B. (2019) · Glia · doi:10.1002/glia.23559 · Cited by 22 · see citing works

Individual neuronal subtypes control initial myelin sheath growth and stabilization

Nelson, H. N., Treichel, A. J., Dankert, E. N., Martell, M. R., Kaiser, A. J., Trudel, A. G., Gronseth, J. R., Maas, S. T., Bergen, S. R., & Hines, J. H. (2020) · Neural Development · doi:10.1186/s13064-020-00149-3 · Cited by 18 · see citing works

Axonal Regulation of Central Nervous System Myelination: Structure and Function

Klingseisen, A., & Lyons, D. A. (2017) · The Neuroscientist · doi:10.1177/1073858417703030 · Cited by 77 · see citing works

Investigating axon-oligodendrocyte interactions during myelinated axon formation in vivo

Mensch, S. (2015) · ERA

The relationship between developing oligodendrocyte units and maturing axons during myelinogenesis in the anterior medullary velum of neonatal rats

Butt, A. M., Ibrahim, M. A. A., & Berry, M. (1997) · Journal of Neurocytology · doi:10.1023/a:1018556702353 · Cited by 61 · see citing works

Neuronal activity biases axon selection for myelination in vivo

Hines, J. H., Ravanelli, A. M., Schwindt, R. K., Scott, E. K., & Appel, B. (2015) · Nature Neuroscience · doi:10.1038/nn.3992 · Cited by 453 · see citing works