QuPath: Open source software for digital pathology image analysis

Random Forests

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PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer

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Heat Shock Factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer

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An aberrant immune–epithelial progenitor niche drives viral lung sequelae

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A prenatal skin atlas reveals immune regulation of human skin morphogenesis

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Plasma cells are enriched in localized prostate cancer in Black men and are associated with improved outcomes

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MPS1 inhibition primes immunogenicity of KRAS-LKB1 mutant lung cancer

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Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition

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Deep-Learning–Based Characterization of Tumor-Infiltrating Lymphocytes in Breast Cancers From Histopathology Images and Multiomics Data

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Early-life inflammation primes a T helper 2 cell–fibroblast niche in skin

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Multi-scale integrative analyses identify THBS2+ cancer-associated fibroblasts as a key orchestrator promoting aggressiveness in early-stage lung adenocarcinoma

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Estrogen receptor positive breast cancers have patient specific hormone sensitivities and rely on progesterone receptor

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Combining CNN-based histologic whole slide image analysis and patient data to improve skin cancer classification

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Predicting Metastatic Potential in Pheochromocytoma and Paraganglioma: A Comparison of PASS and GAPP Scoring Systems

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Microplastic consumption induces inflammatory signatures in the colon and prolongs a viral arthritis

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Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad

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GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection

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Tissue morphology influences the temporal program of human brain organoid development

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An open source automated tumor infiltrating lymphocyte algorithm for prognosis in melanoma

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Integrative multi-omic cancer profiling reveals DNA methylation patterns associated with therapeutic vulnerability and cell-of-origin

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Delayed tumor-draining lymph node irradiation preserves the efficacy of combined radiotherapy and immune checkpoint blockade in models of metastatic disease

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Spatial immune scoring system predicts hepatocellular carcinoma recurrence

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Cross-Priming Dendritic Cells Exacerbate Immunopathology After Ischemic Tissue Damage in the Heart

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MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer

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The G protein signaling regulator RGS3 enhances the GTPase activity of KRAS

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Development and characterisation of acquired radioresistant breast cancer cell lines

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Molecular Features of Cancers Exhibiting Exceptional Responses to Treatment

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Single-cell Profiles and Prognostic Impact of Tumor-Infiltrating Lymphocytes Coexpressing CD39, CD103, and PD-1 in Ovarian Cancer

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Single-cell RNA-seq unravels alterations of the human spermatogonial stem cell compartment in patients with impaired spermatogenesis

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Artificial intelligence-assisted system for precision diagnosis of PD-L1 expression in non-small cell lung cancer

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Ex vivo organotypic culture system of precision-cut slices of human pancreatic ductal adenocarcinoma

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Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma

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Targeting stromal cell sialylation reverses T cell-mediated immunosuppression in the tumor microenvironment

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Best Practices for Spatial Profiling for Breast Cancer Research with the GeoMx® Digital Spatial Profiler

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BioImage Model Zoo: A Community-Driven Resource for Accessible Deep Learning in BioImage AnalysisPreprint

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GZMKhigh CD8+ T effector memory cells are associated with CD15high neutrophil abundance in non-metastatic colorectal tumors and predict poor clinical outcome

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Spatial signatures for predicting immunotherapy outcomes using multi-omics in non-small cell lung cancer

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Glycosphingolipid synthesis mediates immune evasion in KRAS-driven cancer

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Chemotherapy induces myeloid-driven spatially confined T cell exhaustion in ovarian cancer

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Identification of the skeletal progenitor cells forming osteophytes in osteoarthritis

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Spatial transcriptomics landscape of lesions from non-communicable inflammatory skin diseases

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The activity of tertiary lymphoid structures in high grade serous ovarian cancer is governed by site, stroma, and cellular interactions

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Integrative spatial analysis reveals tumor heterogeneity and immune colony niche related to clinical outcomes in small cell lung cancer

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Myeloid Cell-associated Resistance to PD-1/PD-L1 Blockade in Urothelial Cancer Revealed Through Bulk and Single-cell RNA Sequencing

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Characterization of immune cell populations in the tumor microenvironment of colorectal cancer using high definition spatial profiling

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A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection

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WNT11-FZD7-DAAM1 signalling supports tumour initiating abilities and melanoma amoeboid invasion

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C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress–Induced Ferroptosis in FLT3 -Mutant Leukemia

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Single cell and spatial transcriptomics highlight the interaction of club-like cells with immunosuppressive myeloid cells in prostate cancer

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Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition

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Spatial and Temporal Heterogeneity of Panel-Based Tumor Mutational Burden in Pulmonary Adenocarcinoma: Separating Biology From Technical Artifacts

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Local blood coagulation drives cancer cell arrest and brain metastasis in a mouse model

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Multiclass classification of breast cancer histopathology images using multilevel features of deep convolutional neural network

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Multiplex protein imaging in tumour biology

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First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses

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Spatially restricted and ontogenically distinct hepatic macrophages are required for tissue repair

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Mapping the cellular origin and early evolution of leukemia in Down syndrome

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The Effects of COVID-19 on the Placenta During Pregnancy

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Nanosensor-based monitoring of autophagy-associated lysosomal acidification in vivo

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Computational pathology in cancer diagnosis, prognosis, and prediction – present day and prospects

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Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms

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Combination immunotherapy and radiotherapy causes an abscopal treatment response in a mouse model of castration resistant prostate cancer

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Histological validation of in vivo assessment of cancer tissue inhomogeneity and automated morphological segmentation enabled by Optical Coherence Elastography

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