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Systematic review and meta-analysis of depression, anxiety, and suicidal ideation among Ph.D. students
Abstract
University administrators and mental health clinicians have raised concerns about depression and anxiety among Ph.D. students, yet no study has systematically synthesized the available evidence in this area. After searching the literature for studies reporting on depression, anxiety, and/or suicidal ideation among Ph.D. students, we included 32 articles. Among 16 studies reporting the prevalence of clinically significant symptoms of depression across 23,469 Ph.D. students, the pooled estimate of the proportion of students with depression was 0.24 (95% confidence interval [CI], 0.18–0.31; I 2 = 98.75%). In a meta-analysis of the nine studies reporting the prevalence of clinically significant symptoms of anxiety across 15,626 students, the estimated proportion of students with anxiety was 0.17 (95% CI, 0.12–0.23; I 2 = 98.05%). We conclude that depression and anxiety are highly prevalent among Ph.D. students. Data limitations precluded our ability to obtain a pooled estimate of suicidal ideation prevalence. Programs that systematically monitor and promote the mental health of Ph.D. students are urgently needed.
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“Average symptom severity typically falls in the mild range9–11.”
From Prevalence and severity of mental health problems in early-career researchers: a systematic review and meta-analysis (2026) · cites this paper as [11]
In the citing paper
“recent studies suggest that this population experiences a disproportionate degree of psychological distress, including clinically defined syndromes such as depression, generalized anxiety disorder (GAD) and burnout, or individual symptoms such as stress, poor sleep and suicidal ideation1,9–11.”
From Prevalence and severity of mental health problems in early-career researchers: a systematic review and meta-analysis (2026) · cites this paper as [11]
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“For example, the most recent estimates on depression include data up to November 201911.”
From Prevalence and severity of mental health problems in early-career researchers: a systematic review and meta-analysis (2026) · cites this paper as [11]
In the citing paper
“Our findings are broadly consistent with those of other meta-analyses, but they fall on the higher end of previously reported ranges of 21–24% for depressive symptoms and 17–30% for anxiety symptoms9–11.”
From Prevalence and severity of mental health problems in early-career researchers: a systematic review and meta-analysis (2026) · cites this paper as [11]
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“These findings are in line with those of previous meta-analyses, which found that low-quality primary studies or those using non-random sampling techniques reported higher prevalence rates for depressive10 and anxiety symptoms11.”
From Prevalence and severity of mental health problems in early-career researchers: a systematic review and meta-analysis (2026) · cites this paper as [11]
In the citing paper
“These findings are broadly consistent with those of other meta-analyses10,11, which also reported no consistent effect of gender, country income level or academic system.”
From Prevalence and severity of mental health problems in early-career researchers: a systematic review and meta-analysis (2026) · cites this paper as [11]
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Family and Academic Stress and Their Impact on Students' Depression Level and Academic Performance
Deng, Y., Cherian, J., Khan, N. U. N., Kumari, K., Sial, M. S., Comite, U., Gavurova, B., & Popp, J. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.869337 · Cited by 371
Dreisoerner, A., Goetz, V., Frohnmayer, D., Tran, U. S., Voracek, M., & Nater, U. M. (2026) · Nature Human Behaviour · doi:10.1038/s41562-026-02505-5 · Cited by 2
Long, F., Xu, Z., Ngah, A. H., & Wang, H. (2026) · International Journal of Mental Health Promotion · doi:10.32604/ijmhp.2026.089822
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- Satinsky, E. N., Kimura, T., Kiang, M. V., Abebe, R., Cunningham, S., Lee, H., Lin, X., Liu, C. H., Rudan, I., Sen, S., Tomlinson, M., Yaver, M., & Tsai, A. C.
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- Scientific Reports
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- 2021-07-13
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- 11
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- 2045-2322
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- PMC8277873
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