Autophagy in healthy aging and disease

Repertoires of Autophagy in the Pathogenesis of Ocular Diseases

Li, Y., Jiang, Q. L., Cao, G.-F., Yao, J., & Yan, B. (2015) · Cellular Physiology and Biochemistry · doi:10.1159/000373980 · Cited by 16,351

The Hallmarks of Aging

López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013) · Cell · doi:10.1016/j.cell.2013.05.039 · Cited by 14,982

DNA methylation age of human tissues and cell types

Horvath, S. (2013) · Genome Biology · doi:10.1186/gb-2013-14-10-r115 · Cited by 7,075

Origin and physiological roles of inflammation

Medzhitov, R. (2008) · Nature · doi:10.1038/nature07201 · Cited by 6,618

Induction of the Vitamin D Receptor Attenuates Autophagy Dysfunction-Mediated Cell Death Following Traumatic Brain Injury

Cui, C., Cui, J., Jin, F., Cui, Y., Li, R., Jiang, X., Tian, Y., Wang, R. C., Jiang, P., & Gao, J. (2017) · Cellular Physiology and Biochemistry · doi:10.1159/000479571 · Cited by 5,214

The NLRP3 inflammasome: molecular activation and regulation to therapeutics

Swanson, K. V., Deng, M., & Ting, J. P.-Y. (2019) · Nature Reviews Immunology · doi:10.1038/s41577-019-0165-0 · Cited by 4,884

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

Pankiv, S., Clausen, T. H., Lamark, T., Brech, A., Bruun, J.-A., Outzen, H., Øvervatn, A., Bjørkøy, G., & Johansen, T. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m702824200 · Cited by 4,578

Autophagy and Viruses: Adversaries or Allies?

Dong, X., & Levine, B. (2013) · Journal of Innate Immunity · doi:10.1159/000346388 · Cited by 4,444

Resveratrol improves health and survival of mice on a high-calorie diet

Baur, J. A., Pearson, K. J., Price, N. L., Jamieson, H. A., Lerin, C., Kalra, A., Prabhu, V. V., Allard, J. S., Lopez-Lluch, G., Lewis, K., et al. (2006) · Nature · doi:10.1038/nature05354 · Cited by 4,290

CHIP: A Co-chaperone for Degradation by the Proteasome and Lysosome

Chakraborty, A., & Edkins, A. L. (2022) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-031-14740-1_12 · Cited by 24

Role of Microbiota-Modified Bile Acids in the Regulation of Intracellular Organelles and Neurodegenerative Diseases

Kiriyama, Y., & Nochi, H. (2023) · Genes · doi:10.3390/genes14040825 · Cited by 22

Oxidative stress and inflammation: the root causes of aging

Sobhon, P., Savedvanich, G., & Weerakiet, S. (2023) · Exploration of Medicine · doi:10.37349/emed.2023.00129 · Cited by 26

Post-translational modifications of ATG8 proteins – an emerging mechanism of autophagy control

Nieto-Torres, J. L., Zaretski, S., Liu, T., Adams, P. D., & Hansen, M. (2023) · Journal of Cell Science · doi:10.1242/jcs.259725 · Cited by 23

β-Hydroxybutyrate Administered at Reperfusion Reduces Infarct Size and Preserves Cardiac Function by Improving Mitochondrial Function Through Autophagy

Chu, Y., Hua, Y., He, L., He, J. H., Chen, Y., Yang, J., Mahmoud, I., Zeng, F., Zeng, X., Benavides, G. A., et al. (2023) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2023.11.001 · Cited by 23

Functional role of autophagy in testicular and ovarian steroidogenesis

Afzal, A., Zhang, Y., Afzal, H., Saddozai, U. A. K., Zhang, L., Ji, X., & Khawar, M. B. (2024) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2024.1384047 · Cited by 21

Heat-killed probiotic Levilactobacillus brevis MKAK9 and its exopolysaccharide promote longevity by modulating aging hallmarks and enhancing immune responses in Caenorhabditis elegans

Kumar, A., Saha, M. K., Kumar, V., Bhattacharya, A., Barge, S., Mukherjee, A. K., Kalita, M. C., & Khan, M. R. (2024) · Immunity & Ageing · doi:10.1186/s12979-024-00457-w · Cited by 24

The Role of Ginseng and Its Bioactive Compounds in Aging: Cells and Animal Studies

Lee, D., Hooten, N. N., O’Connell, J. F., Lee, B., & Kim, Y. (2025) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-111523-121753 · Cited by 22

Autophagy takes it all – autophagy inducers target immune aging

Zinecker, H., & Simon, A. K. (2022) · Disease Models & Mechanisms · doi:10.1242/dmm.049345 · Cited by 22

EEG/ERP evidence of possible hyperexcitability in older adults with elevated beta-amyloid

Devos, H., Gustafson, K. M., Liao, K., Ahmadnezhad, P., Estes, B. J., Martin, L. E., Mahnken, J. D., Brooks, W. M., & Burns, J. M. (2022) · Translational Neurodegeneration · doi:10.1186/s40035-022-00282-5 · Cited by 19

Cisplatin-induced cell death increases the degradation of the MRE11-RAD50-NBS1 complex through the autophagy/lysosomal pathway

Belmonte‐Fernández, A., Herrero‐Ruiz, J., Galindo‐Moreno, M., Limón‐Mortés, M. C., Mora‐Santos, M., Sáez, C., Japón, M. Á., Tortolero, M., & Romero, F. (2022) · Cell Death and Differentiation · doi:10.1038/s41418-022-01100-1 · Cited by 18

Molecular mechanisms of autophagy and implications in liver diseases

Wu, Y., Tan, H. W. S., Lin, J.-Y., Shen, H., Wang, H., & Lu, G. X. (2023) · Liver Research · doi:10.1016/j.livres.2023.02.002 · Cited by 24

Microbial–Immune Crosstalk in Elderly-Onset Inflammatory Bowel Disease: Unchartered Territory

Meng, G., Monaghan, T. M., Duggal, N. A., Tighe, P., & Peerani, F. (2023) · Journal of Crohn s and Colitis · doi:10.1093/ecco-jcc/jjad025 · Cited by 21

Use of Oleuropein and Hydroxytyrosol for Cancer Prevention and Treatment: Considerations about How Bioavailability and Metabolism Impact Their Adoption in Clinical Routine

Gervasi, F., & Pojero, F. (2024) · Biomedicines · doi:10.3390/biomedicines12030502 · Cited by 24

Lutein and the Underlying Neuroprotective Promise against Neurodegenerative Diseases

Iyer, S., Bhat, I., & Sheshappa, M. B. (2024) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202300409 · Cited by 22

Towards Healthy Longevity: Comprehensive Insights from Molecular Targets and Biomarkers to Biological Clocks

Yusri, K., Kumar, S., Fong, S., Gruber, J., & Sorrentino, V. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25126793 · Cited by 23

No energy, no autophagy—Mechanisms and therapeutic implications of autophagic response energy requirements

Mandić, M., Paunović, V., Vucicevic, L. M., Kosić, M., Mijatović, S., Trajković, V., & Harhaji-Trajkovic, L. M. (2024) · Journal of Cellular Physiology · doi:10.1002/jcp.31366 · Cited by 22

Dysfunction of astrocytic glycophagy exacerbates reperfusion injury in ischemic stroke

Guo, H., Li, Y., Wang, S., Yang, Y., Xu, T., Zhao, J., Wang, J., Zuo, W., Wang, P., Zhao, G., et al. (2024) · Redox Biology · doi:10.1016/j.redox.2024.103234 · Cited by 20

Dialogue between mitochondria and endoplasmic reticulum-potential therapeutic targets for age-related cardiovascular diseases

Chen, C., Dong, X., Zhang, W., Chang, X., & Gao, W. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1389202 · Cited by 22

Autophagy–Lysosome Pathway Dysfunction in Neurodegeneration and Cancer: Mechanisms and Therapeutic Opportunities

Du, M., Yu, Y., Wang, J., & Ji, C. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms27010366 · Cited by 22

Mitochondrial aconitase 1 regulates age‐related memory impairment via autophagy/mitophagy‐mediated neural plasticity in middle‐aged flies

Cho, Y., Kim, G., & Park, J. (2021) · Aging Cell · doi:10.1111/acel.13520 · Cited by 21

LC3-Mediated Mitophagy After CCCP or Vibrio splendidus Exposure in the Pacific Oyster Crassostrea gigas

Sun, J., Lv, X., Leng, J., Wang, L., & Song, L. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.885478 · Cited by 20

Citri Reticulatae Semen Extract Promotes Healthy Aging and Neuroprotection via Autophagy Induction in Caenorhabditis elegans

Long, T., Tang, Y., He, Y.-N., He, C., Chen, X., Guo, M., Wu, J., Yu, L., Yu, C., Law, B. Y. K., et al. (2022) · The Journals of Gerontology Series A · doi:10.1093/gerona/glac136 · Cited by 21

Prebiotic supplementation modulates selective effects of stress on behavior and brain metabolome in aged mice

Cruz-Pereira, J. S., Moloney, G. M., Bastiaanssen, T. F. S., Boscaini, S., Tofani, G. S. S., Borràs-Bisa, J., van de Wouw, M., Fitzgerald, P., Dinan, T. G., Clarke, G. A., et al. (2022) · Neurobiology of Stress · doi:10.1016/j.ynstr.2022.100501 · Cited by 20

Puerarin extends the lifespan of Drosophila melanogaster by activating autophagy

Kang, A.-W., Sun, C. C., Li, H., Zhong, K., Zeng, X., Gu, Z., Li, B., Zhang, X., Gao, J., & Chen, T. (2023) · Food & Function · doi:10.1039/d2fo02800j · Cited by 21

Rhythms in barriers and fluids: Circadian clock regulation in the aging neurovascular unit

Skapetze, L., Owino, S., Lo, E. H., Arai, K., Merrow, M. W., & Harrington, M. E. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106120 · Cited by 20

Hypoxic State of Cells and Immunosenescence: A Focus on the Role of the HIF Signaling Pathway

Troise, D. E., Infante, B., Mercuri, S., Netti, G. S., Ranieri, E., Gesualdo, L., Stallone, G., & Pontrelli, P. (2023) · Biomedicines · doi:10.3390/biomedicines11082163 · Cited by 22

Molecular mechanisms involved in doxorubicin-induced cardiotoxicity: A bibliometrics analysis by VOSviewer

Yarmohammadi, F., Hayes, A. W., & Karimi, G. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02773-2 · Cited by 21

The Janus face of HIF-1α in ischemic stroke and the possible associated pathways

Amin, N., Abbasi, I. N., Wu, F., Shi, Z., Sundus, J., Badry, A., Yuan, X., Zhao, B., Pan, J., Mi, X., et al. (2024) · Neurochemistry International · doi:10.1016/j.neuint.2024.105747 · Cited by 23

Theaflavin 3, 3 ′‐Digallate Delays Ovarian Aging by Improving Oocyte Quality and Regulating Granulosa Cell Function

He, J. H., Yao, G., He, Q., Zhang, T., Fan, H., Bai, Y., Zhang, J., Yang, G., Xu, Z., Hu, J., et al. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/7064179 · Cited by 20

c-MYC-dependent transcriptional inhibition of autophagy is implicated in cisplatin sensitivity in HPV-positive head and neck cancer

Medda, A., Compagnoni, M., Spini, G., Citro, S., Croci, O., Campaner, S., Tagliabue, M., Ansarin, M., & Chiocca, S. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-06248-3 · Cited by 20

Autophagy in Oligodendrocyte Lineage Cells Controls Oligodendrocyte Numbers and Myelin Integrity in an Age-dependent Manner

Chen, H., Yang, G., Xu, D.-E., Du, Y.-T., Zhu, C., Hu, H., Luo, L., Feng, L., Huang, W., Sun, Y., et al. (2024) · Neuroscience Bulletin · doi:10.1007/s12264-024-01292-1 · Cited by 19

Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27

Gallagher, E. R., Oloko, P. T., Fitch, T. C., Brown, E. M., Spruce, L. A., & Holzbaur, E. L. F. (2024) · Current Biology · doi:10.1016/j.cub.2024.10.061 · Cited by 20

USP30 inhibition augments mitophagy to prevent T cell exhaustion

Zhang, R., Gao, F., Li, J., Jin, J., Chen, K., Chaudhuri, S., Liao, Z., Xiao, T., Yang, X., Wen, H., et al. (2025) · Science Advances · doi:10.1126/sciadv.adv6902 · Cited by 21

Reproductive aging in biological females: mechanisms and immediate consequences

Muhammad, Y. A. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1658592 · Cited by 26

P. edulis Extract Protects Against Amyloid-β Toxicity in Alzheimer’s Disease Models Through Maintenance of Mitochondrial Homeostasis via the FOXO3/DAF-16 Pathway

Cao, S., Aman, Y., Fang, E. F., & Tencomnao, T. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-02904-5 · Cited by 21

Protein Quality Control at the Sarcomere: Titin Protection and Turnover and Implications for Disease Development

Kötter, S., & Krüger, M. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.914296 · Cited by 22

Dietary Methylglyoxal Exposure Induces Alzheimer’s Disease by Promoting Amyloid β Accumulation and Disrupting Autophagy in Caenorhabditis elegans

Wei, C., Li, S.-W., Wu, C., How, C. M., & Pan, M. (2022) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c03411 · Cited by 19

The role of phenothiazine derivatives in autophagy regulation: A systematic review

Otręba, M., Stojko, J., & Rzepecka‐Stojko, A. (2022) · Journal of Applied Toxicology · doi:10.1002/jat.4397 · Cited by 22

Rescue of Mitochondrial Function in Hutchinson-Gilford Progeria Syndrome by the Pharmacological Modulation of Exportin CRM1

Monterrubio-Ledezma, F., Navarro‐García, F., Massieu, L., Mondragón‐Flores, R., Soto-Ponce, L. A., Magaña, J. J., & Cisneros, B. (2023) · Cells · doi:10.3390/cells12020275 · Cited by 20

Autophagy mediates a direct synergistic interaction during co-transmission of two distinct arboviruses by insect vectors

Jia, D., Liang, Q., Chen, H., Liu, H., Li, G., Zhang, X., Chen, Q., Wang, A., & Wèi, T. (2023) · Science China Life Sciences · doi:10.1007/s11427-022-2228-y · Cited by 19

Chaperone-mediated autophagy dysregulation during aging impairs hepatic fatty acid oxidation via accumulation of NCoR1

Choi, Y., Yun, S. H., Yu, J., Mun, Y., Lee, W., Park, C. J., Han, B. W., & Lee, B. (2023) · Molecular Metabolism · doi:10.1016/j.molmet.2023.101784 · Cited by 20

Cardioprotective effect of naringin against the ischemia/reperfusion injury of aged rats

Shackebaei, D., Hesari, M., Ramezani-Aliakbari, S., Pashaei, M., Yarmohammadi, F., & Ramezani‐Aliakbari, F. (2023) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-023-02692-2 · Cited by 22

GAS-STING: a classical DNA recognition pathways to tumor therapy

Wang, X., Lin, M., Zhu, L., & Ye, Z. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1200245 · Cited by 22

ZNFX1 promotes AMPK-mediated autophagy against Mycobacterium tuberculosis by stabilizing Prkaa2 mRNA

Liu, H., Han, Z., Chen, L.-R., Zhang, J., Zhang, Z., Chen, Y., Liu, F., Wang, K., Liu, J., Sai, N., et al. (2023) · JCI Insight · doi:10.1172/jci.insight.171850 · Cited by 19

Microphysiological systems for human aging research

Park, S., Laskow, T. C., Chen, J., Guha, P., Dawn, B., & Kim, D. (2024) · Aging Cell · doi:10.1111/acel.14070 · Cited by 21

Protein Quality Control Systems and ER Stress as Key Players in SARS-CoV-2-Induced Neurodegeneration

Gavilán, E., Medina-Guzman, R., Bahatyrevich-Kharitonik, B., & Ruano, D. (2024) · Cells · doi:10.3390/cells13020123 · Cited by 20

Involvement of regulated cell deaths in aging and age-related pathologies

Torre, L. D., Beato, A., Capone, V., Carannante, D., Verrilli, G., Favale, G., Gaudio, N. D., Megchelenbrink, W., Benedetti, R., Altucci, L., et al. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102251 · Cited by 20

Phasic/tonic glial GABA differentially transduce for olfactory adaptation and neuronal aging

Cheng, H., Du, C., Li, X., Al-Sheikh, U., Duan, D., Fan, Y., Zhu, L., Zeng, W.-X., Hu, Z., Tong, X.-J., et al. (2024) · Neuron · doi:10.1016/j.neuron.2024.02.006 · Cited by 19

Propolis as an autophagy modulator in relation to its roles in redox balance and inflammation regulation

Lesmana, R., Tandean, S., Christoper, A., Suwantika, A. A., Wathoni, N., Abdulah, R., Fearnley, J., Bankova, V. S., & Zulhendri, F. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116745 · Cited by 19

Isorhapontigenin delays senescence and matrix degradation of nucleus pulposus cells via PI3K/AKT/mTOR-mediated autophagy pathway in vitro and alleviates intervertebral disc degeneration in vivo

Wang, Z., Ma, J., Sun, Y., Jin, Z., Zheng, R., Li, Y., Yu, H., Ye, H., Wu, Y., Ge, X., et al. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112717 · Cited by 19

Establishing network pharmacology between natural polyphenols and Alzheimer’s disease using bioinformatic tools – An advancement in Alzheimer’s research

Subramanian, A., Tamilanban, T., Subramaniyan, V., Sekar, M., Kumar, V., Janakiraman, A. K., & Kayarohanam, S. (2024) · Toxicology Reports · doi:10.1016/j.toxrep.2024.101715 · Cited by 19

Autophagy in Tissue Repair and Regeneration

Moreno-Blas, D., Adell, T., & González‐Estévez, C. (2025) · Cells · doi:10.3390/cells14040282 · Cited by 22

Systematic in vitro analysis of therapy resistance in glioblastoma cell lines by integration of clonogenic survival data with multi-level molecular data

Schnöller, L. E., Piehlmaier, D., Weber, P., Brix, N., Fleischmann, D. F., Nieto, A. E., Selmansberger, M., Heider, T., Heß, J., Niyazi, M., et al. (2023) · Radiation Oncology · doi:10.1186/s13014-023-02241-4 · Cited by 19

The emerging importance of lymphangiogenesis in aging and aging-associated diseases

Ji, R. (2024) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2024.111975 · Cited by 21

Nanomedicine Approaches for Autophagy Modulation in Cancer Therapy

Mahri, S., Villa, R., Shiau, Y., Tang, M., Racacho, K. J., Zong, Q., Chowdhury, S., Hua, T., Godinez, F., Birkeland, A. C., et al. (2025) · Small Science · doi:10.1002/smsc.202400607 · Cited by 20

Viral Infections in Elderly Individuals: A Comprehensive Overview of SARS-CoV-2 and Influenza Susceptibility, Pathogenesis, and Clinical Treatment Strategies

Huang, Y., Li, S., Ye, W., Wang, H., Su, J., Gao, L., Shi, R., Mou, X., Leng, S. X., Xiao, C., et al. (2025) · Vaccines · doi:10.3390/vaccines13040431 · Cited by 19

Chronic Inflammation as an Underlying Mechanism of Ageing and Ageing-Related Diseases

Chung, K. W., Kim, D. H., Jung, H. J., Arulkumar, R., Chung, H. Y., & Yu, B. P. (2023) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-031-26576-1_3 · Cited by 20

The platelet transcriptome and proteome in Alzheimer’s disease and aging: an exploratory cross-sectional study

de Sousa, D. M. B., Poupardin, R., Villeda, S., Schroer, A. B., Fröhlich, T., Frey, V., Staffen, W., Mrowetz, H., Altendorfer, B., Unger, M. S., et al. (2023) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2023.1196083 · Cited by 20

Role of NFE2L1 in the Regulation of Proteostasis: Implications for Aging and Neurodegenerative Diseases

Chandran, A., Oliver, H., & Rochet, J. (2023) · Biology · doi:10.3390/biology12091169 · Cited by 19

The SLC38A9–mTOR axis is involved in autophagy in the juvenile yellow catfish (Pelteobagrus fulvidraco) under ammonia stress

Li, X., Wang, S., Zhang, M., & Li, M. (2023) · Environmental Pollution · doi:10.1016/j.envpol.2023.123211 · Cited by 18

Molecular Insights into Aggrephagy: Their Cellular Functions in the Context of Neurodegenerative Diseases

Cóppola-Segovia, V., & Reggiori, F. (2024) · Journal of Molecular Biology · doi:10.1016/j.jmb.2024.168493 · Cited by 18

Autophagy and metabolic aging: Current understanding and future applications

Raza, S. (2024) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2024.119753 · Cited by 19

Old age alters inflammation and autophagy signaling in the brain, leading to exacerbated neurological outcomes after spinal cord injury in male mice

Lei, Z., Ritzel, R. M., Li, Y., Li, H., Faden, A. I., & Wu, J. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.06.023 · Cited by 19

Neoantigen sequestrated autophagosomes as therapeutic cancer vaccines

Zhang, J., Cao, J., Wang, L., Li, S., Meng, F., Liang, X., Jiang, H., Luo, R., Zhu, D., Zhang, F., et al. (2024) · Journal of Controlled Release · doi:10.1016/j.jconrel.2024.10.019 · Cited by 18

Golgiphagy: a novel selective autophagy to the fore

Chen, Y., Wu, Y., Tian, X., Shao, G., Lin, Q., & Sun, A. (2024) · Cell & Bioscience · doi:10.1186/s13578-024-01311-8 · Cited by 18

Diosmetin alleviates AFB1-induced endoplasmic reticulum stress, autophagy, and apoptosis via PI3K/AKT pathway in mice

Li, Z., Liu, M., Li, J., Yan, G., & Xu, X. (2025) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2025.117997 · Cited by 19

Aging and senescence: Key players in brain tumor progression and drug resistance

Zhang, C., Neha, N., Zhang, J., Dhaha, P., Li, X., Mishra, S. K., Fleishman, J. S., Parvez, S., Jha, S. K., & Huang, M. (2025) · Drug Resistance Updates · doi:10.1016/j.drup.2025.101228 · Cited by 17

Engineered Extracellular Vesicles Derived from Juvenile Mice Enhance Mitochondrial Function in the Aging Bone Microenvironment and Achieve Rejuvenation

Zheng, J., Ren, Y., Ke, J., Zhu, G., Wang, Z., Shi, X., & Wang, Y. (2025) · ACS Nano · doi:10.1021/acsnano.4c17989 · Cited by 18

Targeting the Electron Transport System for Enhanced Longevity

Radovic, M., Gartzke, L. P., Wink, S. E., van der Kleij, J. A., Politiek, F. A., & Krenning, G. (2025) · Biomolecules · doi:10.3390/biom15050614 · Cited by 17

Addressing osteoblast senescence: Molecular pathways and the frontier of anti‐ageing treatments

Zhang, Z., Liu, P., Song, Y., Ma, L., Xu, Y., Lei, J., Tong, B., Zhu, D., Liang, H., Wang, H., et al. (2025) · Clinical and Translational Medicine · doi:10.1002/ctm2.70417 · Cited by 20

The dual role of glycogen synthase kinase-3 beta (GSK3β) in neurodegenerative pathologies: interplay between autophagy and disease progression

Alhassan, H. H., Janiyani, K., Surti, M., Adnan, M., & Patel, M. B. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1693805 · Cited by 17

Microglia in Brain Aging and Age-Related Diseases: Friends or Foes?

Ishikawa, K., Fujikawa, R., Okita, K., Kimura, F., Watanabe, T., Katsurabayashi, S., & Iwasaki, K. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262311494 · Cited by 18

Molecular Mechanism Underlying the Regulatory Effect of Vine Tea on Metabolic Syndrome by Targeting Redox Balance and Gut Microbiota

Zhou, X., Song, Y., Zeng, C., Zhang, H., Lv, C., Shi, M., & Qin, S. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.802015 · Cited by 17

Traditional herbs: mechanisms to combat cellular senescence

Wang, L., Wang, J., Yang, Z., Wang, Y., Zhao, T., Luo, W., Liang, T., & Zheng, Y. (2023) · Aging · doi:10.18632/aging.205269 · Cited by 18

Cellular stress management by caspases

Baena-López, L. A., Wang, L., & Wendler, F. (2024) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2023.102314 · Cited by 17

Aryl hydrocarbon receptor: Linking environment to aging process in elderly patients with asthma

Yang, T., Wan, R., Tu, W., Avvaru, S. N., & Gao, P. (2024) · Chinese Medical Journal · doi:10.1097/cm9.0000000000002960 · Cited by 18

Driving autophagy – the role of molecular motors

Nambiar, A., & Manjithaya, R. R. (2024) · Journal of Cell Science · doi:10.1242/jcs.260481 · Cited by 17

Novel naphthoquinone-1H-1,2,3-triazole hybrids: Design, synthesis and evaluation as inductors of ROS-mediated apoptosis in the MCF-7 cells

de Souza, A. S., Dias, D. S., Ribeiro, R. C. B., Costa, D. C. S., de Moraes, M. G., Pinho, D. R., Masset, M. E. G., Marins, L. M., Valle, S. P., de Carvalho, C. J. C., et al. (2024) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2024.117671 · Cited by 17

Cellular Models of Aging and Senescence

Kim, B., Lee, D. I., Basisty, N., & Dai, D.-F. (2025) · Cells · doi:10.3390/cells14161278 · Cited by 16

MLKL-USP7-UBA52 signaling is indispensable for autophagy in brain through maintaining ubiquitin homeostasis

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