Cited by 448Birth, Development, and HealthStress Responses and CortisolMaternal Mental Health During Pregnancy and Postpartum

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The stress of being born

Lagercrantz, Hugo, Slotkin, Theodore A.·1986·Scientific American

DOI 10.1038/scientificamerican0486-100

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Varendi, H., Porter, R. H., & Winberg, J. (2002) · Behavioral Neuroscience · doi:10.1037/0735-7044.116.2.206 · Cited by 63
Congenital hypoventilation and impaired hypoxic response in Nurr1 mutant mice
Nsegbe, É., Wallén‐Mackenzie, Å., Dauger, S., et al. (2004) · The Journal of Physiology · doi:10.1113/jphysiol.2003.058560 · Cited by 60
“Furthermore, stress, e.g. during birth (Lagercrantz & Slotkin, 1986), rapidly induces Nurr1 (Honkaniemi et al. 2000) and increases the expression of tyrosine hydroxylase (Iwawaki et al. 2000).”
BackgroundSelf-citation
Prenatal nicotine exposure in rhesus monkeys compromises development of brainstem and cardiac monoamine pathways involved in perinatal adaptation and sudden infant death syndrome: Amelioration by Vitamin C
Slotkin, T. A., Seidler, F. J., & Spindel, E. R. (2011) · Neurotoxicology and Teratology · doi:10.1016/j.ntt.2011.02.001 · Cited by 60
“These adverse outcomes are directly related to each other, since vaginal delivery and SIDS both involve the ability to survive acute hypoxia, involving patterns of cardiorespiratory responses that are unique to the neonate (Kinney, 2009; Lagercrantz and Slotkin, 1986).”
Self-citation
Novel mechanism of human fetal growth regulation: A potential role of lanugo, vernix caseosa and a second tactile system of unmyelinated low-threshold C-afferents
Bystrova, K. (2008) · Medical Hypotheses · doi:10.1016/j.mehy.2008.09.033 · Cited by 59
Maternal contributions to sensory experience in the fetal and newborn rat (Rattus norvegicus).
Ronca, A. E., Lamkin, C. A., & Alberts, J. R. (1993) · Journal of comparative psychology · doi:10.1037/0735-7036.107.1.61 · Cited by 59
Caesarean section: impact on mother and child
Boutsikou, T., & Malamitsi‐Puchner, A. (2011) · Acta Paediatrica · doi:10.1111/j.1651-2227.2011.02477.x · Cited by 56
“for survival, during the hypoxic events of delivery (54).”
Background
Development of monoamine systems after neonatal anoxia in rats
Dell'Anna, M. E., Luthman, J., Lindqvist, E., & Olson, L. (1993) · Brain Research Bulletin · doi:10.1016/0361-9230(93)90070-r · Cited by 58
Mode of Delivery and Asthma at School Age in 9 European Birth Cohorts
Rusconi, F., Zugna, D., Annesi‐Maesano, I., Baïz, N., Barros, H., Correia, S., Duijts, L., Forastiere, F., Inskip, H. M., Kelleher, C. C., et al. (2017) · American Journal of Epidemiology · doi:10.1093/aje/kwx021 · Cited by 57
Developmental perspectives on interpersonal affective touch
Crucianelli, L., & Filippetti, M. L. (2020) · Topoi · doi:10.1007/s11245-018-9565-1 · Cited by 56
“These findings seem to suggest that bodily representation is highly malleable in AN or to use Legrand (2010) words, it is “dis-integrated”, in the sense that eating disorders are not only characterized by over-objectification of their physical body but also by weakened body-ownership (Legrand 2010).”
Background
Skin Conductance Changes During the First Year of Life in Full-Term Infants
HERNES, K. G., Mørkrid, L., Fremming, A., Ødegården, S., Martinsen, Ø. G., & Storm, H. (2002) · Pediatric Research · doi:10.1203/00006450-200212000-00005 · Cited by 58
Breastfeeding and infant‐mother interaction
Zetterström, R. H. (1999) · Acta Paediatrica · doi:10.1111/j.1651-2227.1999.tb01293.x · Cited by 57
“During delivery thefetusis subjectedto a severestress situation, which is mirrored by an extremely high concentrationof stresshormones,such as catecholamines, in cord blood, the concentrationof which is about40%higherthanin patientswith pheochromocytoma(15).”
Background
BREASTFEEDING, SKIN-TO-SKIN CONTACT, AND MOTHER-INFANT INTERACTIONS OVER INFANTS' FIRST THREE MONTHS
Bigelow, A. E., Power, M., Gillis, D. E., MacLellan‐Peters, J., Alex, M. R., & McDonald, C. (2013) · Infant Mental Health Journal · doi:10.1002/imhj.21424 · Cited by 63

Authors: Lagercrantz, H., & Slotkin, T. A.
ORCID: Lagercrantz, Hugo
Slotkin, Theodore A.
Venue: Scientific American
Publisher: Springer Science and Business Media LLC
Published: 1986-04
Volume: 254
Issue: 4
Pages: 100-107
ISSN: 0036-8733 (ISSN-L)
DOI: 10.1038/scientificamerican0486-100
OpenAlex: W2012602762
Cited by: 448
References: 0
Citations by year: 2026: 8 · 2025: 6 · 2024: 5 · 2023: 8 · 2022: 10 · 2021: 7 · 2020: 15 · 2019: 15 · 2018: 12 · 2017: 6 · 2016: 15 · 2015: 15 · 2014: 25 · 2013: 11 · 2012: 18
FWCI: 11.23
Type: journal article
Language: en
Open access: closed
Locations: Scientific American (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
Keywords: births, stress, childbirth, maternal stress
MeSH terms: Adrenal Medulla, Animals, Asphyxia Neonatorum, Catecholamines, Female, Fetal Hypoxia, Fetus, Gestational Age, Humans, Infant, Newborn, Labor, Obstetric, Pregnancy, Respiratory Physiological Phenomena, Sheep, Stress, Physiological, Rats

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