The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Fecal microbiota imbalance in Mexican children with type 1 diabetes
Open accessAbstract
Dysbiosis of the intestinal microbiota affecting the gut barrier could be triggering Type 1 Diabetes (T1D), the second most frequent autoimmune disease in childhood. This study compared the structure of the fecal microbiota in 29 mestizo children aged 7–18 years, including 8 T1D at onset, 13 T1D after 2 years treatment and 8 healthy controls. Clinical information was collected, predisposing haplotypes were determined; the fecal DNA was extracted, the V4 region of the 16S rRNA gene amplified and 454-pyrosequenced. The newly diagnosed T1D cases had high levels of the genus Bacteroides (p < 0.004), whereas the control group had a gut microbiota dominated by Prevotella. Children with T1D treated for ≥2 years had levels of Bacteroides and Prevotella compared to those of the control group. The gut microbiota of newly diagnosed T1D cases is altered, but whether it is involved in disease causation or is a consequence of host selection remains unclear.
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Cited by
RETRACTED ARTICLE: Role of the gut microbiome in chronic diseases: a narrative review
Vijay, A., & Valdes, A. M. (2022) · European Journal of Clinical Nutrition · doi:10.1038/s41430-021-00991-6 · Cited by 361
RetractedPrecup, G., & Vodnar, D.-C. (2019) · British Journal of Nutrition · doi:10.1017/s0007114519000680 · Cited by 378
Connecting the immune system, systemic chronic inflammation and the gut microbiome: the role of sex
Rizzetto, L., Fava, F., Tuohy, K. M., & Selmi, C. (2018) · Journal of Autoimmunity · doi:10.1016/j.jaut.2018.05.008 · Cited by 331
Codella, R., Luzi, L., & Terruzzi, I. (2018) · Digestive and Liver Disease · doi:10.1016/j.dld.2017.11.016 · Cited by 158
Metadata
- Authors
- Mejía-León, M. E., Petrosino, J. F., Ajami, N. J., Domínguez-Bello, M. G., & de la Barca, A. M. C.
- Venue
- Scientific Reports
- Published
- 2014-01-22
- Volume
- 4
- Issue
- 1
- Pages
- 3814-3814
- ISSN
- 2045-2322 (ISSN-L)
- OpenAlex
- W1989012476
- Cited by
- 235
- References
- 8
- FWCI
- 8.27
- Type
- journal article
- Language
- en
- Open access
- gold
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