CoChat
Sign Up
Cited by 346Phytochemicals and Antioxidant ActivitiesGenomics, phytochemicals, and oxidative stressBioactive natural compounds

The DOI matches its Crossref record; 121 of the 121 references it cites were found in a registry or an index.

Chemopreventive effects of natural dietary compounds on cancer development

Pan, Min-Hsiung, Ho, Chi-Tang·2008·Chemical Society Reviews
DOI 10.1039/b801558a
Open this paper in CoChat — free account

Abstract

Chemoprevention, a relatively new and promising strategy to prevent cancer, is defined as the use of natural dietary compounds and/or synthetic substances to block, inhibit, reverse, or retard the process of carcinogenesis. The chemopreventive effects elicited by these natural dietary compounds are believed to include antioxidative, anti-inflammatory activity, induction of phase II enzymes, apoptosis, and cell cycle arrest. Many mechanisms have been shown to account for the anticarcinogenic actions of natural dietary compounds; attention has recently been focused on intracellular-signaling cascades as common molecular targets for various chemopreventive natural dietary compounds. In this critical review, we will summarize current knowledge on natural dietary compounds that act through the signaling pathways and modulate gene expression to induce detoxifying enzymes, programmed cell death, anti-inflammatory, and anti-proliferative effects, thus providing evidence for these substances in cancer chemopreventive action (128 references).

Overview

Integrity signals

Registry

Crossref · 10.1039/b801558a

Cites

121 of 121 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

2 retracted

Show all 121 references

Research works printed but not linked: 7

  1. Chew, 2003, Anticancer Res., 23, 3333
  2. McNally, 2007, Int. J. Mol. Med., 19, 165
  3. Aggarwal, 2004, Anticancer Res., 24, 2783
  4. Kode, 2008, Am. J. Physiol., 294, L478
  5. Ferrer, 2005, Neoplasia (Ann Arbor, MI, U. S.), 7, 37
  6. Lu, 2006, In Vivo, 20, 69
  7. Lin, 2005, Anticancer Res., 25, 2069

Cited by

Sorted by citations

Items 301–342 of 342

Related

See all

Metadata

Authors
Pan, M.-H., & Ho, C.-T.
Affiliations
  • National Kaohsiung Marine University (TW)
  • Rutgers, The State University of New Jersey (US)
Corresponding author
Ho, Chi-Tang
ORCID
Venue
Chemical Society Reviews
Publisher
Royal Society of Chemistry (RSC)
Published
2008
Volume
37
Issue
11
Pages
2558
ISSN
  • 0306-0012 (ISSN-L)
  • 1460-4744
DOI
10.1039/b801558a
OpenAlex
W2046704995
Cited by
346
References
121
Citations by year
2026: 4 · 2025: 5 · 2024: 11 · 2023: 11 · 2022: 13 · 2021: 13 · 2020: 19 · 2019: 18 · 2018: 17 · 2017: 25 · 2016: 19 · 2015: 31 · 2014: 35 · 2013: 38 · 2012: 27
FWCI
1.74
Type
journal article
Language
en
Open access
closed
Locations
  • Chemical Society Reviews (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics, phytochemicals, and oxidative stress
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Drug Discovery › Bioactive natural compounds
Keywords
chemoprevention, carcinogenesis, phase II enzymes, apoptosis, cell cycle arrest, anti-inflammatory activity, antioxidant activity, intracellular signaling, gene expression modulation, antiproliferative activity
MeSH terms
Animals, Antioxidants, Carotenoids, Cell Cycle, Diet, Enzyme Induction, Flavonoids, Humans, Neoplasms, Terpenes, Fatty Acids, Omega-3, Anticarcinogenic Agents, Apoptosis, Isothiocyanates, Proanthocyanidins, Flavonolignans

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review