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Cited by 521

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Biomedical applications of chemically-modified silk fibroin

Open access
Murphy, Amanda R., Kaplan, David L.·2009·Journal of Materials Chemistry

Abstract

Silk proteins belong to a class of unique, high molecular weight, block copolymer-like proteins that have found widespread use in biomaterials and regenerative medicine. The useful features of these proteins, including self-assembly, robust mechanical properties, biocompatibility and biodegradability can be enhanced through a variety of chemical modifications. These modifications provide chemical handles for the attachment of growth factors, cell binding domains and other polymers to silk, expanding the range of cell and tissue engineering applications attainable. This review focuses on the chemical reactions that have been used to modify the amino acids in silk proteins, and describes their utility in biomedical applications.

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Crossref · 10.1039/b905802h

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Metadata

Authors
Murphy, A. R., & Kaplan, D. L.
Venue
Journal of Materials Chemistry
Published
2009
Volume
19
Issue
36
Pages
6443
ISSN
  • 0959-9428 (ISSN-L)
  • 1364-5501
OpenAlex
W2028509138
Cited by
521
References
4
FWCI
4.51
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Biomedical applications of chemically-modified silk fibroin. https://app.cochat.ai/papers/10.1039/b905802h
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Murphy, A. R., & Kaplan, D. L. (2009). Biomedical applications of chemically-modified silk fibroin. Journal of Materials Chemistry. https://doi.org/10.1039/b905802h

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.