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Cited by 393

The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.

Cyclodextrin-based gene delivery systems

Open access
Mellet, Carmen Ortiz, Fernández, José M. García, Benito, Juan M.·2011·Chem. Soc. Rev.

Abstract

Cyclodextrin (CD) history has been largely dominated by their unique ability to form inclusion complexes with guests fitting in their hydrophobic cavity. Chemical funcionalization was soon recognized as a powerful mean for improving CD applications in a wide range of fields, including drug delivery, sensing or enzyme mimicking. However, 100 years after their discovery, CDs are still perceived as novel nanoobjects of undeveloped potential. This critical review provides an overview of different strategies to promote interactions between CD conjugates and genetic material by fully exploiting the inside-outside/upper-lower face anisotropy of the CD nanometric platform. Covalent modification, self-assembling and supramolecular ligation can be put forward with the ultimate goal to build artificial viruses for programmed and efficient gene therapy (222 references).

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Registry

Crossref · 10.1039/c0cs00019a

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Metadata

Authors
Mellet, C. O., Fernández, J. M. G., & Benito, J. M.
Venue
Chem. Soc. Rev.
Published
2011
Volume
40
Issue
3
Pages
1586-1608
ISSN
  • 0306-0012 (ISSN-L)
  • 1460-4744
OpenAlex
W2104349169
Cited by
393
References
9
FWCI
1.27
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Cyclodextrin-based gene delivery systems. https://app.cochat.ai/papers/10.1039/c0cs00019a
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Mellet, C. O., Fernández, J. M. G., & Benito, J. M. (2011). Cyclodextrin-based gene delivery systems. Chem. Soc. Rev. https://doi.org/10.1039/c0cs00019a

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.